amiodarone has been researched along with Colonic Neoplasms in 6 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fourteen patients with Adr-resistant tumors were treated with Adr and AM." | 1.28 | In vitro and in vivo modulation of multi-drug resistance with amiodarone. ( de Vries, EG; Meijer, C; Mulder, NH; Mulder, PO; Nanninga, AG; Uges, DR; van der Graaf, WT; Vellenga, E, 1991) |
| "previously with syngeneic colon cancer cells." | 1.27 | Amiodarone-induced enhancement of doxorubicin and 4'-deoxydoxorubicin cytotoxicity to rat colon cancer cells in vitro and in vivo. ( Chauffert, B; Hammann, A; Martin, F; Martin, M; Michel, MF, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schuetz, EG | 1 |
| Beck, WT | 1 |
| Schuetz, JD | 1 |
| Benoit, L | 1 |
| Duvillard, C | 1 |
| L'Helgouarc'h, JL | 1 |
| Chauffert, B | 3 |
| van der Graaf, WT | 1 |
| de Vries, EG | 1 |
| Uges, DR | 1 |
| Nanninga, AG | 1 |
| Meijer, C | 1 |
| Vellenga, E | 1 |
| Mulder, PO | 1 |
| Mulder, NH | 1 |
| Kopacz, DJ | 1 |
| Rey, D | 1 |
| Coudert, B | 1 |
| Dumas, M | 1 |
| Martin, F | 2 |
| Martin, M | 1 |
| Hammann, A | 1 |
| Michel, MF | 1 |
1 trial available for amiodarone and Colonic Neoplasms
| Article | Year |
|---|---|
Amiodarone is more efficient than verapamil in reversing resistance to anthracyclines in tumour cells.
Topics: Adenocarcinoma; Amiodarone; Animals; Antibiotics, Antineoplastic; Cell Line; Colonic Neoplasms; Dose | 1987 |
5 other studies available for amiodarone and Colonic Neoplasms
| Article | Year |
|---|---|
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, No | 1996 |
[Intratumoral chemotherapy in an experimental animal model: another therapeutic possibility in cancerology].
Topics: Amiodarone; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Ag | 1999 |
In vitro and in vivo modulation of multi-drug resistance with amiodarone.
Topics: Adult; Amiodarone; Biological Transport; Carcinoma, Small Cell; Cell Line; Cell Survival; Colonic Ne | 1991 |
Continuous spinal anaesthesia for abdominal surgery in a patient receiving amiodarone.
Topics: Adenocarcinoma; Amiodarone; Anesthesia, Spinal; Arrhythmias, Cardiac; Bupivacaine; Colon; Colonic Ne | 1991 |
Amiodarone-induced enhancement of doxorubicin and 4'-deoxydoxorubicin cytotoxicity to rat colon cancer cells in vitro and in vivo.
Topics: Adenocarcinoma; Amiodarone; Animals; Benzofurans; Cell Division; Cell Nucleus; Cells, Cultured; Colo | 1986 |