Page last updated: 2024-10-22

amiodarone and Cirrhosis

amiodarone has been researched along with Cirrhosis in 10 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone (AMD), a medicine used to treat life-threatening arrhythmias, is frequently linked to pulmonary fibrosis (PF)."8.31Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin. ( Abdelhamid, WG; El Tabaa, MM; Elgharabawy, RM, 2023)
"Amiodarone is a di-iodated benzofuran derivative that is commonly used to treat patients with various cardiac arrhythmias."7.79[A case of simultaneously occurred amiodarone-induced hepatitis and hypothyroidism]. ( Chae, HB; Cho, YS; Han, JH; Kang, KM; Kim, JS; Lim, JC; Park, SM, 2013)
"By preventing isoprenaline induced myocardial injury and fibrosis, amiodarone may have a cardioprotective role."7.69Amiodarone protection against myocardial injury and fibrosis induced by isoprenaline is abolished by thyroid hormone. ( Cespedes, C; Dussaillant, G; Jalil, JE, 1994)
"Amiodarone is effective in treating persistent atrial fibrillation compared with other antiarrhythmic drugs."5.33Effects of amiodarone on electrical and structural remodeling induced in a canine rapid pacing-induced persistent atrial fibrillation model. ( Ashikaga, K; Furukawa, K; Iwasa, A; Kimura, M; Kobayashi, T; Motomura, S; Okumura, K; Owada, S; Sasaki, S, 2006)
"Amiodarone (AMD), a medicine used to treat life-threatening arrhythmias, is frequently linked to pulmonary fibrosis (PF)."4.31Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin. ( Abdelhamid, WG; El Tabaa, MM; Elgharabawy, RM, 2023)
"Amiodarone is a di-iodated benzofuran derivative that is commonly used to treat patients with various cardiac arrhythmias."3.79[A case of simultaneously occurred amiodarone-induced hepatitis and hypothyroidism]. ( Chae, HB; Cho, YS; Han, JH; Kang, KM; Kim, JS; Lim, JC; Park, SM, 2013)
"By preventing isoprenaline induced myocardial injury and fibrosis, amiodarone may have a cardioprotective role."3.69Amiodarone protection against myocardial injury and fibrosis induced by isoprenaline is abolished by thyroid hormone. ( Cespedes, C; Dussaillant, G; Jalil, JE, 1994)
"Amiodarone is a potent and efficacious antiarrhythmic agent, yet associated with its use are life-threatening pulmonary fibrosis and hepatotoxicity."3.68Repeated amiodarone exposure in the rat: toxicity and effects on hepatic and extrahepatic monooxygenase activities. ( Brien, JF; Daniels, JM; Leeder, RG; Massey, TE, 1990)
"Based on this case amiodarone-related pneumonitis will be discussed, which due to a lack of pathognomonic symptoms is often difficult to diagnose and for which there are few treatment options available."1.35[Amiodarone-induced pneumonitis. Lethal complication in a patient after thoracic surgery]. ( Fisseler-Eckhoff, A; Ghezel-Ahmadi, V; Kürschner, VC; Obenhaus, T; Schirren, J; Schmitz, JE, 2008)
"Amiodarone is effective in treating persistent atrial fibrillation compared with other antiarrhythmic drugs."1.33Effects of amiodarone on electrical and structural remodeling induced in a canine rapid pacing-induced persistent atrial fibrillation model. ( Ashikaga, K; Furukawa, K; Iwasa, A; Kimura, M; Kobayashi, T; Motomura, S; Okumura, K; Owada, S; Sasaki, S, 2006)
"Amiodarone, 150 mg, was injected over 15 seconds intravenously into 9 patients, 52 +/- 9 years of age, weighing between 65 and 98 kg (mean = 81 +/- 15."1.30Amiodarone concentration in human myocardium after rapid intravenous administration. ( Agapitos, E; Alexopoulos, G; Anastasiou-Nana, MI; Karli, JN; Margari, ZJ; Nanas, JN; Patsi, EN; Stamatelopoulos, SF, 1999)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Harb, I1
Ashour, H1
Rashed, LA1
Mostafa, A1
Samir, M1
Aboulhoda, BE1
El-Hanbuli, H1
Rashwan, E1
Mahmoud, H1
El Tabaa, MM2
Elgharabawy, RM1
Abdelhamid, WG1
Arunachalam, K1
Maan, A1
Chu, A1
Cho, YS1
Han, JH1
Chae, HB1
Kim, JS1
Kang, KM1
Park, SM1
Lim, JC1
Hori, Y1
Nakahara, S1
Mine, S1
Anjo, N1
Fujii, A1
Ueda, Y1
Taguchi, I1
Ghezel-Ahmadi, V1
Kürschner, VC1
Fisseler-Eckhoff, A1
Schirren, J1
Schmitz, JE1
Obenhaus, T1
Ashikaga, K1
Kobayashi, T1
Kimura, M1
Owada, S1
Sasaki, S1
Iwasa, A1
Furukawa, K1
Motomura, S1
Okumura, K1
Dussaillant, G1
Jalil, JE1
Cespedes, C1
Anastasiou-Nana, MI1
Nanas, JN1
Alexopoulos, G1
Karli, JN1
Margari, ZJ1
Agapitos, E1
Patsi, EN1
Stamatelopoulos, SF1
Daniels, JM1
Leeder, RG1
Brien, JF1
Massey, TE1

Reviews

1 review available for amiodarone and Cirrhosis

ArticleYear
Atrial Fibrillation in Hypertrophic Cardiomyopathy: Evidence-based Review About Mechanism, Complications and Management.
    Critical pathways in cardiology, 2020, Volume: 19, Issue:2

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomyopathy

2020

Other Studies

9 other studies available for amiodarone and Cirrhosis

ArticleYear
Nicorandil mitigates amiodarone-induced pulmonary toxicity and fibrosis in association with the inhibition of lung TGF-β1/PI3K/Akt1-p/mTOR axis in rats.
    Clinical and experimental pharmacology & physiology, 2023, Volume: 50, Issue:1

    Topics: Amiodarone; Animals; Fibrosis; Lung; Mammals; Nicorandil; Phosphatidylinositol 3-Kinase; Phosphatidy

2023
Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin.
    Inflammopharmacology, 2023, Volume: 31, Issue:3

    Topics: Amiodarone; Animals; Fibrosis; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphatidylinositol 3

2023
[A case of simultaneously occurred amiodarone-induced hepatitis and hypothyroidism].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2013, Volume: 62, Issue:1

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Female; Fibrosis; Hu

2013
Pathological autopsy of a patient that underwent a successful ablation of an electrical storm from the left ventricular summit.
    Heart and vessels, 2016, Volume: 31, Issue:12

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Autopsy; Catheter Ablation; Electrocardiography; Electroph

2016
[Amiodarone-induced pneumonitis. Lethal complication in a patient after thoracic surgery].
    Der Anaesthesist, 2008, Volume: 57, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Carcinoma, Non-Small-Cell Lung; Diagnosis, Differential; F

2008
Effects of amiodarone on electrical and structural remodeling induced in a canine rapid pacing-induced persistent atrial fibrillation model.
    European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2

    Topics: Action Potentials; Administration, Oral; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrill

2006
Amiodarone protection against myocardial injury and fibrosis induced by isoprenaline is abolished by thyroid hormone.
    Cardiovascular research, 1994, Volume: 28, Issue:7

    Topics: Amiodarone; Animals; Fibrosis; Fluorescent Antibody Technique; Heart; Isoproterenol; Male; Myocardiu

1994
Amiodarone concentration in human myocardium after rapid intravenous administration.
    Cardiovascular drugs and therapy, 1999, Volume: 13, Issue:3

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Body Weight; Cardiomyopathy, Dilated; Female; Fibro

1999
Repeated amiodarone exposure in the rat: toxicity and effects on hepatic and extrahepatic monooxygenase activities.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:9

    Topics: Amiodarone; Animals; Biotransformation; Body Weight; Drug Administration Schedule; Fibrosis; Injecti

1990