amiodarone has been researched along with Cholestasis in 5 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacokinetic parameters were derived from plasma samples obtained over a 24-h period." | 1.27 | Effect of renal failure or biliary stasis on the pharmacokinetics of amiodarone in the rat. ( Bernhard, R; Ferguson, RK; Fruncillo, RJ; Marchion, C; Swanson, BN, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García Lobato, E | 1 |
| García Lobato, C | 1 |
| Briegas Morera, D | 1 |
| Rangel Mayoral, JF | 1 |
| Salti, Z | 1 |
| Cloche, P | 1 |
| Weber, P | 1 |
| Houssemand, G | 1 |
| Vollmer, F | 1 |
| Adler, M | 1 |
| Ros, P | 1 |
| Cremer, M | 1 |
| Quiriny, M | 1 |
| Henry, JP | 1 |
| Lecocq, E | 1 |
| Morse, RM | 1 |
| Valenzuela, GA | 1 |
| Greenwald, TP | 1 |
| Eulie, PJ | 1 |
| Wesley, RC | 1 |
| McCallum, RW | 1 |
| Fruncillo, RJ | 1 |
| Swanson, BN | 1 |
| Bernhard, R | 1 |
| Marchion, C | 1 |
| Ferguson, RK | 1 |
2 reviews available for amiodarone and Cholestasis
| Article | Year |
|---|---|
[A case of cholestatic hepatitis caused by amiodarone].
Topics: Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Male; Time Factors | 1989 |
[Drug-induced hepatic lesions].
Topics: Adenoma; Amiodarone; Amphetamines; Antineoplastic Agents; Budd-Chiari Syndrome; Carcinoma, Hepatocel | 1986 |
3 other studies available for amiodarone and Cholestasis
| Article | Year |
|---|---|
[Dissociated cholestasis secondary to methimazole in amiodaron-related hyperthyroidism].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Cholestasis; Humans; Hyperthyroidism; | 2016 |
Amiodarone-induced liver toxicity.
Topics: Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Hyperbilirubi | 1988 |
Effect of renal failure or biliary stasis on the pharmacokinetics of amiodarone in the rat.
Topics: Amiodarone; Animals; Benzofurans; Cholestasis; Dealkylation; Glucuronates; Kidney Failure, Chronic; | 1986 |