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amiodarone and Cholestasis, Intrahepatic

amiodarone has been researched along with Cholestasis, Intrahepatic in 4 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Cholestasis, Intrahepatic: Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).

Research Excerpts

ExcerptRelevanceReference
" Because of ischemic cardiomyopathy with paroxysmal atrial fibrillation as well as recurrent ventricular tachycardias and fibrillation he was treated with phenprocoumon and amiodarone (200 mg per day) for 2 years."3.73[Severe intrahepatic cholestasis in a 66-year old male patient with medically treated atrial fibrillation]. ( Brennenstuhl, M; Gundling, F; Nerlich, A; Schepp, W; Schmidt, O; Tillmann, HL, 2005)
"Amiodarone has proved very effective in the treatment of otherwise resistant cardiac tachyarrhythmias."3.67Hepatotoxicity of amiodarone. ( Rumessen, JJ, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gundling, F1
Tillmann, HL1
Schmidt, O1
Brennenstuhl, M1
Nerlich, A1
Schepp, W1
Reshef, R1
Cohen, I1
Shiller, M1
Szvalb, S1
Loberant, N1
Chang, CC1
Petrelli, M1
Tomashefski, JF1
McCullough, AJ1
Rumessen, JJ1

Reviews

1 review available for amiodarone and Cholestasis, Intrahepatic

ArticleYear
Severe intrahepatic cholestasis caused by amiodarone toxicity after withdrawal of the drug: a case report and review of the literature.
    Archives of pathology & laboratory medicine, 1999, Volume: 123, Issue:3

    Topics: Aged; Aged, 80 and over; Amiodarone; Cholestasis, Intrahepatic; Female; Humans; Liver; Microscopy, E

1999

Other Studies

3 other studies available for amiodarone and Cholestasis, Intrahepatic

ArticleYear
[Severe intrahepatic cholestasis in a 66-year old male patient with medically treated atrial fibrillation].
    Der Internist, 2005, Volume: 46, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cholestasis, Intrahepatic; Humans; Ma

2005
Does ursodeoxycholic acid have a place in the treatment of amiodarone-induced cholestasis?
    Journal of clinical gastroenterology, 1994, Volume: 18, Issue:2

    Topics: Aged; Amiodarone; Cardiac Complexes, Premature; Cholestasis, Intrahepatic; Humans; Male; Ursodeoxych

1994
Hepatotoxicity of amiodarone.
    Acta medica Scandinavica, 1986, Volume: 219, Issue:2

    Topics: Aged; Amiodarone; Benzofurans; Cholestasis, Intrahepatic; Humans; Liver Function Tests; Male; Tachyc

1986