amiodarone has been researched along with Cardiomegaly in 15 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Randomized clinical trials of prophylactic amiodarone in patients with congestive heart failure and nonsustained ventricular tachycardia have produced conflicting results." | 4.79 | Evaluation and treatment of nonsustained ventricular tachycardia. ( Wilber, DJ, 1996) |
| "In the adult, Amiodarone is a very effective drug in the treatment of ventricular and supraventricular arrhythmias." | 3.67 | [Amiodarone therapy in childhood: efficacy and side effects]. ( Austoni, P; Danzi, GB; Fancini, P; Figini, A; Mascarello, M; Vignati, G, 1985) |
| "Amiodarone has also been reported to improve symptoms dramatically in some patients with HCM but to cause functional deterioration in others." | 2.38 | Effects of amiodarone on erect and supine exercise haemodynamics and exercise capacity in patients with hypertrophic cardiomyopathy. ( Counihan, PJ; Frenneaux, MP; Lipkin, DP; McKenna, WJ; Porter, A, 1992) |
| "This article discusses arrhythmias in hypertrophic and dilated cardiomyopathy in relation to clinical significance and treatment; when possible, the authors comment on etiology." | 2.37 | Arrhythmias in dilated and hypertrophic cardiomyopathy. ( Goodwin, JF; Krikler, DM; McKenna, WJ, 1984) |
| "Amlodipine did not affect cardiac hypertrophy." | 1.32 | Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system. ( Allen, TJ; Burrell, LM; Cao, Z; Cooper, ME; Davis, BJ; Lassila, M, 2003) |
| "Amiodarone treatment caused a significant rise in pulmonary capillary wedge pressure from 22 +/- 8 to 37 +/- 9 mm Hg (p less than ." | 1.27 | Effects of long-term treatment with amiodarone on exercise hemodynamics and left ventricular relaxation in patients with hypertrophic cardiomyopathy. ( Andries, E; Heyndrickx, GR; Nellens, P; Paulus, WJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rao, DA | 1 |
| Lakdawala, NK | 1 |
| Miller, AL | 1 |
| Loscalzo, J | 1 |
| Onorati, F | 1 |
| Rubino, AS | 1 |
| Mariscalco, G | 1 |
| Serraino, F | 1 |
| Sala, A | 1 |
| Renzulli, A | 1 |
| Vogler, J | 1 |
| Eckardt, L | 1 |
| Lassila, M | 1 |
| Davis, BJ | 1 |
| Allen, TJ | 1 |
| Burrell, LM | 1 |
| Cooper, ME | 1 |
| Cao, Z | 1 |
| Wang, L | 2 |
| Lü, J | 1 |
| Zhang, F | 1 |
| Bai, R | 1 |
| McKenna, WJ | 2 |
| Krikler, DM | 1 |
| Goodwin, JF | 1 |
| Ward, DE | 1 |
| Camm, AJ | 1 |
| Wang, R | 1 |
| Dymond, D | 1 |
| Spurrell, RA | 1 |
| Rutitzky, B | 1 |
| Girotti, AL | 1 |
| Rosenbaum, MB | 1 |
| Williams, MJ | 1 |
| Low, CJ | 1 |
| Restieaux, NJ | 1 |
| Wilber, DJ | 1 |
| López-Mínguez, JR | 1 |
| Merchán Herrera, A | 1 |
| Cimboria Ortega, A | 1 |
| Millán Núñez, V | 1 |
| García-Andoain, JM | 1 |
| Alvarez Suárez-Bárcenas, JM | 1 |
| Martínez de la Concha, L | 1 |
| Fernández de la Concha, J | 1 |
| Alonso Ruiz, F | 1 |
| Frenneaux, MP | 1 |
| Counihan, PJ | 1 |
| Porter, A | 1 |
| Lipkin, DP | 1 |
| Karlson, JA | 1 |
| Hopkins, RW | 1 |
| Moran, JM | 1 |
| Karlson, KE | 1 |
| Vignati, G | 1 |
| Danzi, GB | 1 |
| Austoni, P | 1 |
| Fancini, P | 1 |
| Mascarello, M | 1 |
| Figini, A | 1 |
| Paulus, WJ | 1 |
| Nellens, P | 1 |
| Heyndrickx, GR | 1 |
| Andries, E | 1 |
4 reviews available for amiodarone and Cardiomegaly
| Article | Year |
|---|---|
Pharmacology of myocardial calcium-handling.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Calcium; Calcium Chan | 2012 |
Arrhythmias in dilated and hypertrophic cardiomyopathy.
Topics: Amiodarone; Arrhythmias, Cardiac; Cardiomegaly; Cardiomyopathy, Hypertrophic; Death, Sudden; Electro | 1984 |
Evaluation and treatment of nonsustained ventricular tachycardia.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomegaly; Cardiomyopathy, Dilated; Electrocardiography; Hear | 1996 |
Effects of amiodarone on erect and supine exercise haemodynamics and exercise capacity in patients with hypertrophic cardiomyopathy.
Topics: Adult; Aged; Amiodarone; Cardiomegaly; Cardiomyopathy, Hypertrophic; Exercise; Exercise Test; Female | 1992 |
11 other studies available for amiodarone and Cardiomegaly
| Article | Year |
|---|---|
Clinical problem-solving. In the thick of it.
Topics: alpha-Galactosidase; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomegaly; Codon, N | 2013 |
Results of atrial fibrillation ablation during mitral surgery in patients with poor electro-anatomical substrate.
Topics: Ablation Techniques; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillatio | 2009 |
Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system.
Topics: Alanine; Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Ani | 2003 |
Effects of amiodarone on transmural dispersion of ventricular effective refractory periods across myocardial layers in the normal and hypertrophic canine heart.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cardiomegaly; Dogs; Female; Male; Myocardium; Rats; Ref | 2006 |
Suppression of long-standing incessant ventricular tachycardia by amiodarone.
Topics: Adult; Amiodarone; Benzofurans; Cardiomegaly; Electrocardiography; Humans; Male; Radiography; Tachyc | 1980 |
Efficacy of chronic amiodarone therapy in patients with variant angina pectoris and inhibition of ergonovine coronary constriction.
Topics: Administration, Oral; Adult; Amiodarone; Angina Pectoris, Variant; Benzofurans; Bundle-Branch Block; | 1982 |
Tachycardia and cardiomyopathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomegaly; Child; Chronic Disease; Electrocardiography; Femal | 1996 |
[Ventricular tachycardia in a patient with mid-ventricular hypertrophic myocardiopathy and apical aneurysm].
Topics: Aged; Amiodarone; Atrial Fibrillation; Cardiomegaly; Echocardiography, Transesophageal; Electrocardi | 1997 |
Long-term amiodarone administration protects against global myocardial ischemia.
Topics: Amiodarone; Animals; Cardiomegaly; Heart; Heart Arrest, Induced; Male; Myocardial Reperfusion Injury | 1990 |
[Amiodarone therapy in childhood: efficacy and side effects].
Topics: Administration, Oral; Adolescent; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Cardiomegaly; Child | 1985 |
Effects of long-term treatment with amiodarone on exercise hemodynamics and left ventricular relaxation in patients with hypertrophic cardiomyopathy.
Topics: Adult; Aged; Amiodarone; Benzofurans; Cardiomegaly; Electrocardiography; Female; Hemodynamics; Human | 1986 |