amiodarone has been researched along with Cardiac Hypertrophy in 15 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Randomized clinical trials of prophylactic amiodarone in patients with congestive heart failure and nonsustained ventricular tachycardia have produced conflicting results." | 4.79 | Evaluation and treatment of nonsustained ventricular tachycardia. ( Wilber, DJ, 1996) |
| "In the adult, Amiodarone is a very effective drug in the treatment of ventricular and supraventricular arrhythmias." | 3.67 | [Amiodarone therapy in childhood: efficacy and side effects]. ( Austoni, P; Danzi, GB; Fancini, P; Figini, A; Mascarello, M; Vignati, G, 1985) |
| "Amiodarone has also been reported to improve symptoms dramatically in some patients with HCM but to cause functional deterioration in others." | 2.38 | Effects of amiodarone on erect and supine exercise haemodynamics and exercise capacity in patients with hypertrophic cardiomyopathy. ( Counihan, PJ; Frenneaux, MP; Lipkin, DP; McKenna, WJ; Porter, A, 1992) |
| "This article discusses arrhythmias in hypertrophic and dilated cardiomyopathy in relation to clinical significance and treatment; when possible, the authors comment on etiology." | 2.37 | Arrhythmias in dilated and hypertrophic cardiomyopathy. ( Goodwin, JF; Krikler, DM; McKenna, WJ, 1984) |
| "Amlodipine did not affect cardiac hypertrophy." | 1.32 | Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system. ( Allen, TJ; Burrell, LM; Cao, Z; Cooper, ME; Davis, BJ; Lassila, M, 2003) |
| "Amiodarone treatment caused a significant rise in pulmonary capillary wedge pressure from 22 +/- 8 to 37 +/- 9 mm Hg (p less than ." | 1.27 | Effects of long-term treatment with amiodarone on exercise hemodynamics and left ventricular relaxation in patients with hypertrophic cardiomyopathy. ( Andries, E; Heyndrickx, GR; Nellens, P; Paulus, WJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rao, DA | 1 |
| Lakdawala, NK | 1 |
| Miller, AL | 1 |
| Loscalzo, J | 1 |
| Onorati, F | 1 |
| Rubino, AS | 1 |
| Mariscalco, G | 1 |
| Serraino, F | 1 |
| Sala, A | 1 |
| Renzulli, A | 1 |
| Vogler, J | 1 |
| Eckardt, L | 1 |
| Lassila, M | 1 |
| Davis, BJ | 1 |
| Allen, TJ | 1 |
| Burrell, LM | 1 |
| Cooper, ME | 1 |
| Cao, Z | 1 |
| Wang, L | 2 |
| Lü, J | 1 |
| Zhang, F | 1 |
| Bai, R | 1 |
| McKenna, WJ | 2 |
| Krikler, DM | 1 |
| Goodwin, JF | 1 |
| Ward, DE | 1 |
| Camm, AJ | 1 |
| Wang, R | 1 |
| Dymond, D | 1 |
| Spurrell, RA | 1 |
| Rutitzky, B | 1 |
| Girotti, AL | 1 |
| Rosenbaum, MB | 1 |
| Williams, MJ | 1 |
| Low, CJ | 1 |
| Restieaux, NJ | 1 |
| Wilber, DJ | 1 |
| López-Mínguez, JR | 1 |
| Merchán Herrera, A | 1 |
| Cimboria Ortega, A | 1 |
| Millán Núñez, V | 1 |
| García-Andoain, JM | 1 |
| Alvarez Suárez-Bárcenas, JM | 1 |
| Martínez de la Concha, L | 1 |
| Fernández de la Concha, J | 1 |
| Alonso Ruiz, F | 1 |
| Frenneaux, MP | 1 |
| Counihan, PJ | 1 |
| Porter, A | 1 |
| Lipkin, DP | 1 |
| Karlson, JA | 1 |
| Hopkins, RW | 1 |
| Moran, JM | 1 |
| Karlson, KE | 1 |
| Vignati, G | 1 |
| Danzi, GB | 1 |
| Austoni, P | 1 |
| Fancini, P | 1 |
| Mascarello, M | 1 |
| Figini, A | 1 |
| Paulus, WJ | 1 |
| Nellens, P | 1 |
| Heyndrickx, GR | 1 |
| Andries, E | 1 |
4 reviews available for amiodarone and Cardiac Hypertrophy
| Article | Year |
|---|---|
Pharmacology of myocardial calcium-handling.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Calcium; Calcium Chan | 2012 |
Arrhythmias in dilated and hypertrophic cardiomyopathy.
Topics: Amiodarone; Arrhythmias, Cardiac; Cardiomegaly; Cardiomyopathy, Hypertrophic; Death, Sudden; Electro | 1984 |
Evaluation and treatment of nonsustained ventricular tachycardia.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomegaly; Cardiomyopathy, Dilated; Electrocardiography; Hear | 1996 |
Effects of amiodarone on erect and supine exercise haemodynamics and exercise capacity in patients with hypertrophic cardiomyopathy.
Topics: Adult; Aged; Amiodarone; Cardiomegaly; Cardiomyopathy, Hypertrophic; Exercise; Exercise Test; Female | 1992 |
11 other studies available for amiodarone and Cardiac Hypertrophy
| Article | Year |
|---|---|
Clinical problem-solving. In the thick of it.
Topics: alpha-Galactosidase; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomegaly; Codon, N | 2013 |
Results of atrial fibrillation ablation during mitral surgery in patients with poor electro-anatomical substrate.
Topics: Ablation Techniques; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillatio | 2009 |
Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system.
Topics: Alanine; Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Ani | 2003 |
Effects of amiodarone on transmural dispersion of ventricular effective refractory periods across myocardial layers in the normal and hypertrophic canine heart.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cardiomegaly; Dogs; Female; Male; Myocardium; Rats; Ref | 2006 |
Suppression of long-standing incessant ventricular tachycardia by amiodarone.
Topics: Adult; Amiodarone; Benzofurans; Cardiomegaly; Electrocardiography; Humans; Male; Radiography; Tachyc | 1980 |
Efficacy of chronic amiodarone therapy in patients with variant angina pectoris and inhibition of ergonovine coronary constriction.
Topics: Administration, Oral; Adult; Amiodarone; Angina Pectoris, Variant; Benzofurans; Bundle-Branch Block; | 1982 |
Tachycardia and cardiomyopathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomegaly; Child; Chronic Disease; Electrocardiography; Femal | 1996 |
[Ventricular tachycardia in a patient with mid-ventricular hypertrophic myocardiopathy and apical aneurysm].
Topics: Aged; Amiodarone; Atrial Fibrillation; Cardiomegaly; Echocardiography, Transesophageal; Electrocardi | 1997 |
Long-term amiodarone administration protects against global myocardial ischemia.
Topics: Amiodarone; Animals; Cardiomegaly; Heart; Heart Arrest, Induced; Male; Myocardial Reperfusion Injury | 1990 |
[Amiodarone therapy in childhood: efficacy and side effects].
Topics: Administration, Oral; Adolescent; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Cardiomegaly; Child | 1985 |
Effects of long-term treatment with amiodarone on exercise hemodynamics and left ventricular relaxation in patients with hypertrophic cardiomyopathy.
Topics: Adult; Aged; Amiodarone; Benzofurans; Cardiomegaly; Electrocardiography; Female; Hemodynamics; Human | 1986 |