amiodarone and Cardiac Diseases studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Research Excerpts

Excerpt	Relevance	Reference
"In Japan, intravenous nifekalant (NIF) was often used for direct current cardioversion-resistant ventricular fibrillation (VF), until the use of intravenous amiodarone (AMD) was approved in 2007."	9.14	Comparative study of nifekalant versus amiodarone for shock-resistant ventricular fibrillation in out-of-hospital cardiopulmonary arrest patients. ( Akieda, K; Amino, M; Fujibayashi, D; Fukushima, T; Hashida, T; Higami, S; Inokuchi, S; Kodama, I; Morita, S; Opthof, T; Otsuka, H; Shima, M; Tamura, K; Tanabe, T; Uemura, S; Yoshioka, K, 2010)
"EPS was performed 1 month after starting amiodarone, and Holter-monitoring was recorded before and 1 month after amiodarone in 188 patients with sustained VT/VF because of structural heart diseases."	9.13	Electrophysiologic study-guided amiodarone for sustained ventricular tachyarrhythmias associated with structural heart diseases. ( Aiba, T; Aihara, N; Kamakura, S; Kurita, T; Noda, T; Okamura, H; Satomi, K; Shimizu, W; Suyama, K; Taguchi, A; Yamagata, K, 2008)
"Ninety-two patients with persistent atrial fibrillation (>2 weeks duration) were prospectively randomized into three matched groups: A (n=31, oral amiodarone 400 mg."	9.09	Oral amiodarone increases the efficacy of direct-current cardioversion in restoration of sinus rhythm in patients with chronic atrial fibrillation. ( Aschieri, D; Capucci, A; Piepoli, MF; Rosi, A; Villani, GQ, 2000)
"The efficacy and safety of amiodarone for pharmacological cardioversion of recent-onset atrial fibrillation was examined by reviewing the trials on the subject identified through a comprehensive literature search."	8.82	Amiodarone for pharmacological cardioversion of recent-onset atrial fibrillation. ( Gowda, RM; Khan, IA; Mehta, NJ, 2003)
"Amiodarone is often prescribed in the management of atrial fibrillation (AF) but is known to cause significant end-organ toxicities."	7.81	Mortality risk of long-term amiodarone therapy for atrial fibrillation patients without structural heart disease. ( Adelstein, E; Alam, MB; Jain, SK; Khattak, F; Leef, G; Munir, MB; Patel, D; Qin, D; Rattan, R; Saba, S, 2015)
"Patients with amiodarone-induced thyrotoxicosis (AIT) and left ventricular (LV) systolic dysfunction have a high mortality rate."	7.78	Total thyroidectomy in patients with amiodarone-induced thyrotoxicosis and severe left ventricular systolic dysfunction. ( Bartalena, L; Bogazzi, F; De Napoli, L; Marchello, A; Mariotti, R; Martino, E; Materazzi, G; Miccoli, P; Moretti, M; Rossi, G; Tomisti, L, 2012)
"The aim of this study was to investigate the use of prophylactic magnesium sulphate and amiodarone in treating arrhythmias that may occur following coronary bypass grafting operations."	7.75	Magnesium sulphate and amiodarone prophylaxis for prevention of postoperative arrhythmia in coronary by-pass operations. ( Ari, H; Demirtas, S; Huysal, K; Ozyazicioglu, A; Selimoglu, O; Tiryakioglu, O; Tiryakioglu, SK, 2009)
"Amiodarone-induced thyrotoxicosis is a life-threatening condition."	7.74	Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007)
"Amiodarone, given as a single intravenous bolus through a peripheral vein rapidly reduced ventricular rate and was well tolerated in patients with atrial fibrillation, even in the presence of congestive heart failure and cardiogenic shock."	7.72	Intravenous amiodarone bolus for treatment of atrial fibrillation in patients with advanced congestive heart failure or cardiogenic shock. ( Hofmann, R; Kammler, J; Kypta, A; Leisch, F; Steinwender, C; Wimmer, G, 2004)
"Amioradone-induced hyperthyroidism is a common complication of amiodarone therapy."	7.72	[Prevention of recurrent amiodarone-induced hyperthyroidism by iodine-131]. ( Arlot, S; Hermida, JS; Jarry, G; Moullart, V; Rey, JL; Schvartz, C; Tcheng, E, 2004)
"The efficacy and safety of amiodarone in the management of atrial fibrillation (AF) or flutter in 108 Japanese patients with heart failure was retrospectively examined."	7.71	Effect of low-dose amiodarone on atrial fibrillation or flutter in Japanese patients with heart failure. ( Hagiwara, N; Hosaka, F; Imai, T; Kasanuki, H; Matsuda, N; Shiga, T; Shoda, M; Sugiura, R; Suzuki, T; Wakaumi, M; Yamada, Y, 2002)
"Amiodarone (AD) is an effective antidysrythmic drug, however, there can be serious side effects, such as hepatic and neurological alterations, as well as skin photosensitization, as seen in porphyrias."	7.70	Amiodarone is a pharmacologically safe drug for porphyrias. ( Batlle, A; Enríquez de Salamanca, R; Méndez, M; Parera, V, 1999)
"Amiodarone seems, in this study, to be a very effective antiarrhythmic drug for the treatment of supraventricular tachyarrhythmias."	7.68	[The effectiveness of amiodarone seems to depend highly on the pathology underlying the arrhythmia]. ( de Castro, JJ; Mota, E; Quadrado, C; Soares, Ade O, 1990)
"Amiodarone induces in patients "low T3-syndrome" characterized by normal T4."	7.66	[Amiodarone-induce "low T3-syndrome" (author's transl)]. ( Beckers, C; Jonckheer, MH; Smekens, L, 1978)
"Ventricular arrhythmias represented 13% of the rhythmic indications."	6.38	The value of oral amiodarone in the treatment of ventricular arrhythmias in heart disease. ( Levy, S, 1991)
"In Japan, intravenous nifekalant (NIF) was often used for direct current cardioversion-resistant ventricular fibrillation (VF), until the use of intravenous amiodarone (AMD) was approved in 2007."	5.14	Comparative study of nifekalant versus amiodarone for shock-resistant ventricular fibrillation in out-of-hospital cardiopulmonary arrest patients. ( Akieda, K; Amino, M; Fujibayashi, D; Fukushima, T; Hashida, T; Higami, S; Inokuchi, S; Kodama, I; Morita, S; Opthof, T; Otsuka, H; Shima, M; Tamura, K; Tanabe, T; Uemura, S; Yoshioka, K, 2010)
"EPS was performed 1 month after starting amiodarone, and Holter-monitoring was recorded before and 1 month after amiodarone in 188 patients with sustained VT/VF because of structural heart diseases."	5.13	Electrophysiologic study-guided amiodarone for sustained ventricular tachyarrhythmias associated with structural heart diseases. ( Aiba, T; Aihara, N; Kamakura, S; Kurita, T; Noda, T; Okamura, H; Satomi, K; Shimizu, W; Suyama, K; Taguchi, A; Yamagata, K, 2008)
"Ninety-two patients with persistent atrial fibrillation (>2 weeks duration) were prospectively randomized into three matched groups: A (n=31, oral amiodarone 400 mg."	5.09	Oral amiodarone increases the efficacy of direct-current cardioversion in restoration of sinus rhythm in patients with chronic atrial fibrillation. ( Aschieri, D; Capucci, A; Piepoli, MF; Rosi, A; Villani, GQ, 2000)
"The efficacy and safety of amiodarone for pharmacological cardioversion of recent-onset atrial fibrillation was examined by reviewing the trials on the subject identified through a comprehensive literature search."	4.82	Amiodarone for pharmacological cardioversion of recent-onset atrial fibrillation. ( Gowda, RM; Khan, IA; Mehta, NJ, 2003)
"Amiodarone is one of the most commonly used and effective antiarrhythmic drugs to treat ventricular and supraventricular arrhythmias."	4.31	Amiodarone-induced blue man syndrome: a case report. ( Javanshir, N; Negaresh, M; Salimi, M; Samadi Takaldani, AH, 2023)
" Here, we present the HCV treatment challenges facing a patient with HIV coinfection, prior failure of both HIV-1 and HCV therapy, cirrhosis, end-stage renal failure on haemodialysis, as well as management of drug-drug interactions, especially given the need to receive long-term amiodarone therapy."	3.88	Cure of chronic hepatitis C virus infection in an HIV-coinfected patient with multiple comorbidities and drug interaction challenges. ( Álvarez, H; Bhagani, S; Khoo, S; Llibre, JM; Mariño, A; Schapiro, J; Valcarce, N, 2018)
" Dronedarone is an antiarrhythmic agent that was recently approved for the treatment of atrial fibrillation."	3.85	Dronedarone produces early regression of myocardial remodelling in structural heart disease. ( Delgado-Baeza, E; Delgado-Martos, MJ; Desco, M; Gomez de Diego, JJ; Muñoz-Valverde, D; Quintana-Villamandos, B; Soto-Montenegro, ML, 2017)
"Amiodarone is often prescribed in the management of atrial fibrillation (AF) but is known to cause significant end-organ toxicities."	3.81	Mortality risk of long-term amiodarone therapy for atrial fibrillation patients without structural heart disease. ( Adelstein, E; Alam, MB; Jain, SK; Khattak, F; Leef, G; Munir, MB; Patel, D; Qin, D; Rattan, R; Saba, S, 2015)
"We investigated the effect of amiodarone (AMD) administered intravenously for the treatment of post-operative atrial fibrillation( POAF) after cardiac surgery."	3.80	[Therapeutic use of amiodarone against postoperative fibrillation after cardiac surgery]. ( Araki, E; Kawaharada, N; Muraki, S; Nakashima, S; Osawa, H; Sakurada, T; Sasaki, J, 2014)
"Patients with amiodarone-induced thyrotoxicosis (AIT) and left ventricular (LV) systolic dysfunction have a high mortality rate."	3.78	Total thyroidectomy in patients with amiodarone-induced thyrotoxicosis and severe left ventricular systolic dysfunction. ( Bartalena, L; Bogazzi, F; De Napoli, L; Marchello, A; Mariotti, R; Martino, E; Materazzi, G; Miccoli, P; Moretti, M; Rossi, G; Tomisti, L, 2012)
"The aim of this study was to investigate the use of prophylactic magnesium sulphate and amiodarone in treating arrhythmias that may occur following coronary bypass grafting operations."	3.75	Magnesium sulphate and amiodarone prophylaxis for prevention of postoperative arrhythmia in coronary by-pass operations. ( Ari, H; Demirtas, S; Huysal, K; Ozyazicioglu, A; Selimoglu, O; Tiryakioglu, O; Tiryakioglu, SK, 2009)
"Amiodarone-induced thyrotoxicosis is a life-threatening condition."	3.74	Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007)
"Amiodarone, given as a single intravenous bolus through a peripheral vein rapidly reduced ventricular rate and was well tolerated in patients with atrial fibrillation, even in the presence of congestive heart failure and cardiogenic shock."	3.72	Intravenous amiodarone bolus for treatment of atrial fibrillation in patients with advanced congestive heart failure or cardiogenic shock. ( Hofmann, R; Kammler, J; Kypta, A; Leisch, F; Steinwender, C; Wimmer, G, 2004)
"Amioradone-induced hyperthyroidism is a common complication of amiodarone therapy."	3.72	[Prevention of recurrent amiodarone-induced hyperthyroidism by iodine-131]. ( Arlot, S; Hermida, JS; Jarry, G; Moullart, V; Rey, JL; Schvartz, C; Tcheng, E, 2004)
"The efficacy and safety of amiodarone in the management of atrial fibrillation (AF) or flutter in 108 Japanese patients with heart failure was retrospectively examined."	3.71	Effect of low-dose amiodarone on atrial fibrillation or flutter in Japanese patients with heart failure. ( Hagiwara, N; Hosaka, F; Imai, T; Kasanuki, H; Matsuda, N; Shiga, T; Shoda, M; Sugiura, R; Suzuki, T; Wakaumi, M; Yamada, Y, 2002)
"Amiodarone (AD) is an effective antidysrythmic drug, however, there can be serious side effects, such as hepatic and neurological alterations, as well as skin photosensitization, as seen in porphyrias."	3.70	Amiodarone is a pharmacologically safe drug for porphyrias. ( Batlle, A; Enríquez de Salamanca, R; Méndez, M; Parera, V, 1999)
"The effect of long-term treatment with propafenone, metoprolol and amiodarone was studied on the activity of Na,K-adenosine triphosphatase in lymphocytes and the plasma level of cAMP in patients with ventricular arrhythmias."	3.69	[The effect of treatment with propafenone, metoprolol and amiodarone on lymphocyte sodium efflux and level of cAMP in serum]. ( Kosmala, W, 1995)
"Amiodarone seems, in this study, to be a very effective antiarrhythmic drug for the treatment of supraventricular tachyarrhythmias."	3.68	[The effectiveness of amiodarone seems to depend highly on the pathology underlying the arrhythmia]. ( de Castro, JJ; Mota, E; Quadrado, C; Soares, Ade O, 1990)
"Amiodarone therapy for cardiac arrhythmias is increasingly being recognized to be associated with pulmonary toxicity."	3.67	Life-threatening postoperative pulmonary complications in patients with previous amiodarone pulmonary toxicity undergoing cardiothoracic operations. ( Fishbein, MC; Gang, ES; Kass, RM; Mandel, WJ; Nalos, PC; Peter, T, 1987)
"Amiodarone induces in patients "low T3-syndrome" characterized by normal T4."	3.66	[Amiodarone-induce "low T3-syndrome" (author's transl)]. ( Beckers, C; Jonckheer, MH; Smekens, L, 1978)
"Reports of dilated cardiomyopathy associated with Graves' disease and evidence for TSH-receptors in the human myocardium suggest a relationship between these two diseases."	2.41	[Hyperthyroidism and heart]. ( Weissel, M, 2001)
"Ventricular arrhythmias represented 13% of the rhythmic indications."	2.38	The value of oral amiodarone in the treatment of ventricular arrhythmias in heart disease. ( Levy, S, 1991)
"Amiodarone has been demonstrated to be an important and effective antiarrhythmic agent, as has sotalol."	2.38	Empiric use of amiodarone and sotalol. ( Nora, M; Zipes, DP, 1993)
"Despite advances in ablation of ventricular tachycardia (VT), recognized toxicity of amiodarone, and potential harm of implantable cardioverter defibrillator (ICD) shocks, there appears to be reluctance to pursue catheter ablation."	1.37	Ventricular tachycardia ablation remains treatment of last resort in structural heart disease: argument for earlier intervention. ( Callans, DJ; Frankel, DS; Marchlinski, FE; Mountantonakis, SE; Robinson, MR; Zado, ES, 2011)
"To assess the incidence, severity, and spectrum of neurologic toxic effects associated with administration of amiodarone hydrochloride."	1.35	Frequency, characteristics, and risk factors for amiodarone neurotoxicity. ( Ahlskog, JE; Orr, CF, 2009)
"To determine if amiodarone, highly lipophilic, accumulates in excess with respect to dose in fat tissue during long-term administration, and study if plasma and fat tissue concentrations are correlated with adverse effects."	1.35	Amiodarone concentrations in plasma and fat tissue during chronic treatment and related toxicity. ( Alvarez, JC; Bergmann, JF; Caulin, C; Extramiana, F; Funck-Brentano, C; Lafuente-Lafuente, C; Leenhardt, A; Mouly, S, 2009)
"Atrial thrombosis is a relatively rare event in children."	1.35	Resolution of atrial thrombosis with heparin in a newborn with atrial flutter. ( Angelini, A; Boriani, G; Bronzetti, G; D'Angelo, C; Picchio, FM, 2009)
"Stroke was more frequent in CD (15."	1.33	Chagas disease is an independent risk factor for stroke: baseline characteristics of a Chagas Disease cohort. ( Faiçal, F; Oliveira-Filho, J; Reis, FJ; Torreão, JA; Viana, LC; Vieira-de-Melo, RM; Villar, FA, 2005)
"To understand the bioavailability and mechanistic pathways of cytoprotection by IH636 grape seed proanthocyanidin extract (GSPE, commercially known as ActiVin) a series of in vitro and in vivo studies were conducted."	1.31	Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract. ( Bagchi, D; Bagchi, M; Preuss, HG; Ray, SD; Stohs, SJ, 2002)
"We report a case of arrhythmogenic right ventricular cardiomyopathy with a right ventricular thrombus located inside a single apical aneurysm in the presence of normal right ventricular systolic function."	1.31	[Right ventricular thrombosis in arrhythmogenic cardiomyopathy. A case report]. ( Antonini-Canterin, F; Nicolosi, GL; Pavan, D; Sandrini, R; Zardo, F, 2000)
" Patients received both amiodarone and warfarin for at least 1 year, and the dosage of warfarin was adjusted as clinically necessary to achieve an international normalized ratio of 2 to 3."	1.31	Clinical observations with the amiodarone/warfarin interaction: dosing relationships with long-term therapy. ( Bauman, JL; Sanoski, CA, 2002)
"In patients with ischemic heart disease, recurrences of VT or VF peaked in the morning."	1.31	Absence of a morning peak in ventricular tachycardia and fibrillation events in nonischemic heart disease: analysis of therapies by implantable cardioverter defibrillators. ( Aizawa, Y; Taneda, K, 2001)
"Junctional ectopic tachycardia is favored by high levels of sympathomimetic catecholamines after surgery."	1.31	[The treatment of postoperative junctional ectopic tachycardia]. ( Cabrera Duro, A; Galdeano Miranda, JM; Macua Biurrun, P; Martínez Corrales, P; Pastor Menchaca, E; Pilar Orive, J; Rodrigo Carbonero, D, 2002)
"Although syncope is a frequent clinical entity, the evaluation and treatment of patients with syncope without a clear etiology still remains undefined."	1.30	[Patients with structural heart disease, syncope of unknown etiology and inducible ventricular arrhythmias treated with implantable defibrillators]. ( Aguinaga, L; Anguera, I; Brugada, J; Matas, M; Mont, L; Valentino, M, 1998)
"At the time of the second study congestive heart failure was manifest in 19%, and there was a trend suggesting that congestive heart failure was more likely if the initial LVEF was less than or equal to 35% (p = 0."	1.27	Effect of amiodarone on ventricular function as measured by gated radionuclide angiography. ( Gorham, JR; Graham, EL; Greene, HL; Gross, BW; Kingston, E; Kudenchuk, PJ; Sears, GK; Trobaugh, GB; Tutt, RC; Werner, JA, 1984)
" On the other hand digitalis administered according to age, sex, weight, kidney function, together with amiodarone, can be given at full dosage in patients without cardiac failure."	1.27	[Pharmacological and clinical research on the interaction of digitalis and amiodarone in heart disease patients with varying degrees of cardiac insufficiency]. ( Aquili, C; Ferrari, M; Fornaro, G; Fortina, A; Padrini, R; Piovan, D; Rossi, P; Tomassini, G, 1984)
"Digoxin half-life was prolonged."	1.27	Digoxin toxicity associated with amiodarone therapy in children. ( Hesslein, PS; Koren, G; MacLeod, SM, 1984)
"In Amiodarone-treated euthyroid patients, mean T4, fT4 and rT3 values were significantly (p less than 0,01) higher than those of control subjects; TSH levels were normal in all the groups studied."	1.27	[Thyroid function in patients chronically treated with amiodarone]. ( Bassi, F; Borghi, A; Brocchi, A; Cappelli, G; Fazzini, PF; Gheri, RG; Marchi, F; Paladini, S; Pratesi, E; Pucci, P, 1983)
"Amiodarone has been reported to be a remarkably safe and effective drug in the European and South American experience but American investigators have published conflicting data."	1.27	Safety and efficacy of amiodarone. The low-dose perspective. ( Friehling, TD; Kowey, PR; Marinchak, RA; Stohler, JL; Sulpizi, AM, 1988)
"Hyperthyroidism was a more frequent (9."	1.27	Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy. ( Aghini-Lombardi, F; Aronin, N; Fay, M; Haffajee, C; Lenziardi, M; Macchia, E; Martino, E; Pacchiarotti, A; Rajatanavin, R; Safran, M, 1984)
"Amiodarone is a useful antiarrhythmic agent whose pharmacokinetics are incompletely characterised."	1.27	Plasma amiodarone concentrations during intravenous infusion. ( Hutchings, A; Routledge, PA; Stephens, MR; Watt, AH, 1986)

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (25.49)	18.7374
1990's	21 (20.59)	18.2507
2000's	36 (35.29)	29.6817
2010's	16 (15.69)	24.3611
2020's	3 (2.94)	2.80

Trial	Phase	Enrollment	Study Type	Start Date	Status
A Pharmaco-surgical Approach to Reduce Postoperative Atrial Fibrillation After Cardiac Surgery[NCT05780320]		242 participants (Anticipated)	Observational	2022-09-19	Active, not recruiting
Pragmatic Amiodarone Trial to Reduce Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery[NCT05543278]	Phase 4	242 participants (Anticipated)	Interventional	2023-12-01	Not yet recruiting
Endocardial-Epicardial Radiofrequency Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy[NCT04512911]	Early Phase 1	0 participants (Actual)	Interventional	2023-01-31	Withdrawn (stopped due to IRB approval expired 1/23/2023 and eclipsed the 6 month institutional window where study can be reinitiated via progress report. No enrollment has taken place.)
Using Time-dependent Intravenous Infusions of Amiodarone for Conversions to Sinus Rhythms in Patients With Paroxysmal Atrial Fibrillation[NCT03432663]	Phase 4	60 participants (Actual)	Interventional	2008-08-01	Completed
Effect of Levothyroxine on Serum Adiponectin, Insulin Resistance and Cardiovascular Risk in Patients With Hypothyroidism[NCT02467244]		120 participants (Actual)	Observational	2017-02-01	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Thyroid Disease and the Heart. Current problems in cardiology, 2016, Volume: 41, Issue:2 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Heart Diseases; Hemodynamics; Humans; Hydroxymethylglut	2016
Amiodarone-induced thyrotoxicosis: something new to refine the initial diagnosis? European journal of endocrinology, 2008, Volume: 159, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Heart Diseases; Humans; Thyrotoxicosis	2008
[Amiodaron: decades of administration]. Terapevticheskii arkhiv, 2011, Volume: 83, Issue:8 Topics: Amiodarone; Anti-Arrhythmia Agents; Heart Diseases; Heart Function Tests; Humans; Randomized Control	2011
Amiodarone for pharmacological cardioversion of recent-onset atrial fibrillation. International journal of cardiology, 2003, Volume: 89, Issue:2-3 Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as To	2003
[Drug treatment of atrial fibrillation]. MMW Fortschritte der Medizin, 2006, Apr-13, Volume: 148, Issue:15 Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti	2006
Empiric use of amiodarone and sotalol. The American journal of cardiology, 1993, Nov-26, Volume: 72, Issue:16 Topics: Amiodarone; Cardiomyopathy, Hypertrophic; Coronary Disease; Death, Sudden, Cardiac; Heart Diseases;	1993
Cardiology. Emergency medicine clinics of North America, 1997, Volume: 15, Issue:2 Topics: Amiodarone; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Cardiology; Diagnosis, Different	1997
Management of the older person with ventricular arrhythmias. Journal of the American Geriatrics Society, 1999, Volume: 47, Issue:7 Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors	1999
Thyroid disease and the heart. Heart (British Cardiac Society), 2000, Volume: 84, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Biomarkers; Heart Diseases; Humans; Hyperth	2000
Thyroid hormone and the cardiovascular system. The New England journal of medicine, 2001, Feb-15, Volume: 344, Issue:7 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Heart; Heart Diseases	2001
[Hyperthyroidism and heart]. Wiener klinische Wochenschrift, 2001, Mar-15, Volume: 113, Issue:5-6 Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomyopathy, Dilated; D	2001
The value of oral amiodarone in the treatment of ventricular arrhythmias in heart disease. Drugs, 1991, Volume: 41 Suppl 2 Topics: Administration, Oral; Amiodarone; Arrhythmias, Cardiac; Death, Sudden; Heart Diseases; Humans	1991
[Clinical pharmacology and therapeutic use of cordarone]. Kardiologiia, 1989, Volume: 29, Issue:4 Topics: Amiodarone; Drug Evaluation; Heart Diseases; Humans	1989
Amiodarone and the thyroid. The Quarterly journal of medicine, 1987, Volume: 62, Issue:238 Topics: Amiodarone; Heart; Heart Diseases; Humans; Thyroid Diseases; Thyroid Gland; Thyroid Hormones	1987

Article	Year
Comparative study of nifekalant versus amiodarone for shock-resistant ventricular fibrillation in out-of-hospital cardiopulmonary arrest patients. Journal of cardiovascular pharmacology, 2010, Volume: 55, Issue:4 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electric Countershock; Emergenc	2010
Electrophysiologic study-guided amiodarone for sustained ventricular tachyarrhythmias associated with structural heart diseases. Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:1 Topics: Aged; Amiodarone; Death; Electrocardiography, Ambulatory; Electrophysiologic Techniques, Cardiac; Fe	2008
Oral amiodarone increases the efficacy of direct-current cardioversion in restoration of sinus rhythm in patients with chronic atrial fibrillation. European heart journal, 2000, Volume: 21, Issue:1 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Electric Coun	2000
Prevention of atrial fibrillation after cardiac surgery: the significance of postoperative oral amiodarone. Chest, 2001, Volume: 120, Issue:6 Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiopulmonary	2001
Role of desethylamiodarone in the anticoagulant effect of concurrent amiodarone and warfarin therapy. Journal of cardiovascular pharmacology and therapeutics, 2001, Volume: 6, Issue:4 Topics: Adult; Aged; Amiodarone; Anticoagulants; Drug Interactions; Drug Therapy, Combination; Female; Heart	2001
Clinical characteristics and outcome of patients with high defibrillation thresholds. A multicenter study. Circulation, 1992, Volume: 86, Issue:4 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Coronary Disease; Death, Sudden; Differential Thres	1992
Effects of amiodarone versus quinidine and verapamil in patients with chronic atrial fibrillation: results of a comparative study and a 2-year follow-up. Journal of the American College of Cardiology, 1992, Volume: 19, Issue:5 Topics: Amiodarone; Atrial Fibrillation; Chronic Disease; Drug Therapy, Combination; Electrocardiography; Fe	1992

Article	Year
Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI). European journal of human genetics : EJHG, 2002, Volume: 10, Issue:1 Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; COS Cells; DNA; Heart Block; Heart	2002
Cardioprotective effects of amiodarone in a rat model of epilepsy-induced cardiac dysfunction. Clinical and experimental pharmacology & physiology, 2022, Volume: 49, Issue:3 Topics: Adjuvants, Immunologic; Amiodarone; Animals; Anti-Arrhythmia Agents; Biomarkers; Epilepsy; Glutathio	2022
Experimental Combination Therapy with Amiodarone and Low-Dose Benznidazole in a Mouse Model of Trypanosoma cruzi Acute Infection. Microbiology spectrum, 2022, 02-23, Volume: 10, Issue:1 Topics: Amiodarone; Animals; Chagas Disease; Disease Models, Animal; Drug Therapy, Combination; Heart; Heart	2022
Amiodarone-induced blue man syndrome: a case report. Journal of medical case reports, 2023, Jun-09, Volume: 17, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Defibrillators, Implantable; Heart Disease	2023
Right ventricular tuberculous granuloma. European heart journal. Cardiovascular Imaging, 2017, 12-01, Volume: 18, Issue:12 Topics: Amiodarone; Antitubercular Agents; Arrhythmias, Cardiac; Granuloma; Heart Diseases; Heart Ventricles	2017
Dronedarone produces early regression of myocardial remodelling in structural heart disease. PloS one, 2017, Volume: 12, Issue:11 Topics: Amiodarone; Animals; Atrial Fibrillation; Atrial Remodeling; Dronedarone; Heart Diseases; Humans; Hy	2017
Cure of chronic hepatitis C virus infection in an HIV-coinfected patient with multiple comorbidities and drug interaction challenges. International journal of STD & AIDS, 2018, Volume: 29, Issue:9 Topics: Amiodarone; Antiviral Agents; Coinfection; Comorbidity; Drug Interactions; Female; Heart Diseases; H	2018
Mexiletine as an adjunctive therapy to amiodarone reduces the frequency of ventricular tachyarrhythmia events in patients with an implantable defibrillator. Journal of cardiovascular pharmacology, 2013, Volume: 62, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; Cohort Studies	2013
[Therapeutic use of amiodarone against postoperative fibrillation after cardiac surgery]. Kyobu geka. The Japanese journal of thoracic surgery, 2014, Volume: 67, Issue:5 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Heart Dise	2014
Mortality risk of long-term amiodarone therapy for atrial fibrillation patients without structural heart disease. Cardiology journal, 2015, Volume: 22, Issue:6 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dose-Response Relationship, Drug; Dru	2015
Magnesium sulphate and amiodarone prophylaxis for prevention of postoperative arrhythmia in coronary by-pass operations. Journal of cardiothoracic surgery, 2009, Feb-20, Volume: 4 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Artery Bypass; Creatine Kinase, M	2009
Resolution of atrial thrombosis with heparin in a newborn with atrial flutter. Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:7 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Digoxin; Electrocardiography; Fibrinolytic Agent	2009
Amiodarone concentrations in plasma and fat tissue during chronic treatment and related toxicity. British journal of clinical pharmacology, 2009, Volume: 67, Issue:5 Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Di	2009
Frequency, characteristics, and risk factors for amiodarone neurotoxicity. Archives of neurology, 2009, Volume: 66, Issue:7 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Diseases; Humans; Male; M	2009
Frequency, characteristics, and risk factors for amiodarone neurotoxicity. Archives of neurology, 2009, Volume: 66, Issue:7 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Diseases; Humans; Male; M	2009
Frequency, characteristics, and risk factors for amiodarone neurotoxicity. Archives of neurology, 2009, Volume: 66, Issue:7 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Diseases; Humans; Male; M	2009
Frequency, characteristics, and risk factors for amiodarone neurotoxicity. Archives of neurology, 2009, Volume: 66, Issue:7 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Diseases; Humans; Male; M	2009
Relationship between oral amiodarone and inappropriate therapy from an implantable cardioverter defibrillator. Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:7 Topics: Aged; Amiodarone; Atrial Fibrillation; Defibrillators, Implantable; Female; Heart Diseases; Humans;	2010
Ventricular tachycardia ablation remains treatment of last resort in structural heart disease: argument for earlier intervention. Journal of cardiovascular electrophysiology, 2011, Volume: 22, Issue:10 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Catheter Ablation; Chi-Square Distribution; Defibrillators	2011
Dronedarone: liver damage and cardiac disorders. Negative harm-benefit balance. Prescrire international, 2011, Volume: 20, Issue:120 Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Dronedarone; Heart Disea	2011
[Who protects physicians and patients from guidelines?]. Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:49 Topics: Adenosine; Aged; Amiodarone; Anti-Arrhythmia Agents; Consensus Development Conferences as Topic; Dro	2011
Images in endocrine pathology: thyrotoxicosis associated with destructive thyroiditis. Endocrine pathology, 2012, Volume: 23, Issue:3 Topics: Amiodarone; Heart Diseases; Humans; Male; Middle Aged; Thyroidectomy; Thyroiditis; Thyrotoxicosis; T	2012
Total thyroidectomy in patients with amiodarone-induced thyrotoxicosis and severe left ventricular systolic dysfunction. The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:10 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Diseases; Humans; Male; Middle Aged; Postope	2012
[Optimum heart rate - the current goal of cardiovascular therapy. Position statement of the Polish Cardiac Society Working Group on Cardiovascular Drug Therapy]. Kardiologia polska, 2012, Volume: 70, Issue:10 Topics: Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Di	2012
Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract. Indian journal of experimental biology, 2002, Volume: 40, Issue:6 Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Amiodarone; Analgesics, Non-Narcotic; Ani	2002
A simplified amiodarone regimen to prevent postoperative atrial fibrillation. The Annals of thoracic surgery, 2003, Volume: 75, Issue:6 Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiopulmonary Bypas	2003
Restoring cardiac function without missing a beat. Nursing management, 2001, Volume: 32, Issue:5 Topics: Amiodarone; Anti-Arrhythmia Agents; Brachytherapy; Heart Diseases; Humans; Laser Therapy; Myocardial	2001
[Prevention of recurrent amiodarone-induced hyperthyroidism by iodine-131]. Archives des maladies du coeur et des vaisseaux, 2004, Volume: 97, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Hea	2004
[The cardiologist should suspect more thyroid dysfunction!]. Arquivos brasileiros de cardiologia, 2004, Volume: 82, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Female; Heart Diseases; Humans; Male; Risk Factors; Thyroid Dise	2004
Thyroid dysfunction and cardiological management in patients receiving amiodarone. Arquivos brasileiros de cardiologia, 2004, Volume: 82, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Brazil; Female; Heart Diseases; Humans; Male; Middle Aged; Preva	2004
Left atrial thrombus formation early after mitral valve replacement. Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:5 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Cardiac Output, Low; Echoca	2004
Intravenous amiodarone bolus for treatment of atrial fibrillation in patients with advanced congestive heart failure or cardiogenic shock. Wiener klinische Wochenschrift, 2004, Nov-30, Volume: 116, Issue:21-22 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiograph	2004
Intravenous amiodarone: offender or bystander? Critical care medicine, 2005, Volume: 33, Issue:1 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Critical Care; Dia	2005
Chagas disease is an independent risk factor for stroke: baseline characteristics of a Chagas Disease cohort. Stroke, 2005, Volume: 36, Issue:9 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Chagas Disease; Cohort Studies; Fem	2005
Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. Langenbeck's archives of surgery, 2007, Volume: 392, Issue:6 Topics: Aged; Amiodarone; Anesthesia, Local; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nerve B	2007
Selective prophylaxis of atrial fibrillation with amiodarone after cardiac surgery. Minerva chirurgica, 2006, Volume: 61, Issue:5 Topics: Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Fe	2006
[Prospects for drug therapy in the rehabilitation of the cardiac patient]. Bollettino della Societa italiana di cardiologia, 1980, Volume: 25, Issue:12 Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Benzofurans; Heart Diseases; Humans; Male; Middle Ag	1980
Peripheral neuropathy induced by amiodarone chlorhydrate. A clinicopathological study. Journal of the neurological sciences, 1984, Volume: 63, Issue:2 Topics: Adult; Aged; Amiodarone; Axons; Benzofurans; Heart Diseases; Humans; Inclusion Bodies; Male; Microsc	1984
Can amiodarone induce hyperglycaemia and hypertriglyceridaemia? British medical journal (Clinical research ed.), 1984, Jan-28, Volume: 288, Issue:6413 Topics: Aged; Amiodarone; Benzofurans; Cholesterol; Female; Heart Diseases; Humans; Hyperglycemia; Male; Mid	1984
Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy. Annals of internal medicine, 1984, Volume: 101, Issue:1 Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Goiter; Heart Diseases; Humans; Hyperthyroidism; Hypot	1984
[The effect of amiodarone on thyroid gland function]. Zeitschrift fur Kardiologie, 1984, Volume: 73, Issue:6 Topics: Adolescent; Adult; Aged; Amiodarone; Benzofurans; Female; Heart Diseases; Humans; Male; Middle Aged;	1984
Effect of amiodarone on ventricular function as measured by gated radionuclide angiography. The American journal of cardiology, 1984, Dec-01, Volume: 54, Issue:10 Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Cardiac Output; Female; Heart; Heart Diseases;	1984
[Pharmacological and clinical research on the interaction of digitalis and amiodarone in heart disease patients with varying degrees of cardiac insufficiency]. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:12 Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Digitalis Glycosides; Digoxin; Drug Inte	1984
[Amiodarone in the acute treatment of hyperkinetic arrhythmias in cardiosurgery]. Cardiologia (Rome, Italy), 1983, Volume: 28, Issue:5 Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Drug Evaluation; Female; Heart Diseases;	1983
Digoxin toxicity associated with amiodarone therapy in children. The Journal of pediatrics, 1984, Volume: 104, Issue:3 Topics: Adolescent; Amiodarone; Benzofurans; Cardiomyopathy, Dilated; Child; Child, Preschool; Creatinine; D	1984
[Thyroid function in patients chronically treated with amiodarone]. Giornale italiano di cardiologia, 1983, Volume: 13, Issue:3 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Benzofurans; Female; Heart Diseases; Humans; Hyperthyroidi	1983
[Hyperthyroidism following amiodarone treatment]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Apr-26, Volume: 37, Issue:8 Topics: Adult; Amiodarone; Benzofurans; Female; Graves Disease; Heart Diseases; Humans	1982
[Corneal involvement due to amiodarone therapy]. Harefuah, 1980, Oct-01, Volume: 99, Issue:7 Topics: Adolescent; Adult; Aged; Amiodarone; Benzofurans; Blinking; Corneal Diseases; Female; Heart Diseases	1980
Amiodarone keratopathy. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1980, Volume: 180, Issue:5 Topics: Adolescent; Adult; Aged; Amiodarone; Benzofurans; Corneal Diseases; Female; Heart Diseases; Humans;	1980
[Digoxin-quinidine and digoxin-amiodarone interactions. Effects on blood levels of the cardioactive glycoside]. Giornale italiano di cardiologia, 1981, Volume: 11, Issue:7 Topics: Adult; Aged; Amiodarone; Benzofurans; Coronary Disease; Digoxin; Drug Interactions; Female; Heart Di	1981
Antiarrhythmic drugs and polyneuropathy. The Collaborative Group for the Study of Polyneuropathy. Journal of neurology, neurosurgery, and psychiatry, 1994, Volume: 57, Issue:3 Topics: Adolescent; Adult; Aged; Ambulatory Care; Amiodarone; Anti-Arrhythmia Agents; Electrophysiology; Fem	1994
[The effect of treatment with propafenone, metoprolol and amiodarone on lymphocyte sodium efflux and level of cAMP in serum]. Polskie Archiwum Medycyny Wewnetrznej, 1995, Volume: 94, Issue:1 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cyclic AMP; Female; Heart Dis	1995
Determinants of nonthoracotomy biphasic defibrillation. Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:1 Pt 1 Topics: Age Factors; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Body Surface Area; Defibrilla	1997
[Influence of anti-arrhythmia agents on heart rate variability]. Annales de cardiologie et d'angeiologie, 1997, Volume: 46, Issue:3 Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Ele	1997
Assessment of the cardiac patient for fitness to drive: 1996 update. The Canadian journal of cardiology, 1996, Volume: 12, Issue:11 Topics: Amiodarone; Arrhythmias, Cardiac; Automobile Driving; Defibrillators, Implantable; Electrocardiograp	1996
A pulse of 27 in a man with chronic heart disease. Hospital practice (1995), 1997, Oct-15, Volume: 32, Issue:10 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Drug Overdose; Drug Thera	1997
Right bundle-branch block and ST-segment elevation in leads V1 through V3: a marker for sudden death in patients without demonstrable structural heart disease. Circulation, 1998, Feb-10, Volume: 97, Issue:5 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Bundle-Branch Bl	1998
[Patients with structural heart disease, syncope of unknown etiology and inducible ventricular arrhythmias treated with implantable defibrillators]. Revista espanola de cardiologia, 1998, Volume: 51, Issue:7 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia	1998
Amiodarone is a pharmacologically safe drug for porphyrias. General pharmacology, 1999, Volume: 32, Issue:2 Topics: 5-Aminolevulinate Synthetase; Amiodarone; Ammonia-Lyases; Animals; Anti-Arrhythmia Agents; Feces; He	1999
The placebo effect is alive and well. Health news (Waltham, Mass.), 1999, Oct-01, Volume: 5, Issue:12 Topics: Amiodarone; Heart Diseases; Humans; Patient Compliance; Placebo Effect; Social Behavior	1999
Oral amiodarone reduces incidence of postoperative atrial fibrillation. The Annals of thoracic surgery, 1999, Volume: 68, Issue:5 Topics: Administration, Oral; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiopu	1999
[Right ventricular thrombosis in arrhythmogenic cardiomyopathy. A case report]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2000, Volume: 1, Issue:3 Topics: Acenocoumarol; Adult; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Arrhythmogenic Right Ventr	2000
What is structural heart disease? Clinical cardiology, 2000, Volume: 23, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Flecainide; Heart Diseases; Humans; Practice Patterns, Physician	2000
Hydatid cyst of heart presenting as ventricular tachycardia. The Journal of the Association of Physicians of India, 1999, Volume: 47, Issue:3 Topics: Adolescent; Albendazole; Amiodarone; Anthelmintics; Anti-Arrhythmia Agents; Diagnosis, Differential;	1999
In vivo protection of dna damage associated apoptotic and necrotic cell deaths during acetaminophen-induced nephrotoxicity, amiodarone-induced lung toxicity and doxorubicin-induced cardiotoxicity by a novel IH636 grape seed proanthocyanidin extract. Research communications in molecular pathology and pharmacology, 2000, Volume: 107, Issue:1-2 Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Amiodarone; Animals; Antioxidants; Apopto	2000
Comparison of defibrillation thresholds using monodirectional electrical vector versus bidirectional electrical vector. Italian heart journal : official journal of the Italian Federation of Cardiology, 2001, Volume: 2, Issue:6 Topics: Adult; Aged; Amiodarone; Defibrillators, Implantable; Electric Countershock; Extremities; Female; He	2001
Clinical observations with the amiodarone/warfarin interaction: dosing relationships with long-term therapy. Chest, 2002, Volume: 121, Issue:1 Topics: Aged; Amiodarone; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Fe	2002
Absence of a morning peak in ventricular tachycardia and fibrillation events in nonischemic heart disease: analysis of therapies by implantable cardioverter defibrillators. Pacing and clinical electrophysiology : PACE, 2001, Volume: 24, Issue:11 Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Circadian Rhythm; Defibrillators, Implantable; Female	2001
Long-term efficacy of empirical chronic amiodarone therapy in patients with sustained ventricular tachyarrhythmia and structural heart disease. Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Female; Follow-Up Studies; Heart Diseases; Humans; Male; Middle	2002
[The treatment of postoperative junctional ectopic tachycardia]. Anales espanoles de pediatria, 2002, Volume: 56, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Combined Modality Therapy; Female;	2002
Effect of low-dose amiodarone on atrial fibrillation or flutter in Japanese patients with heart failure. Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:6 Topics: Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Atrial Fibrillation; A	2002
[Amiodarone-induce "low T3-syndrome" (author's transl)]. Annales d'endocrinologie, 1978, Volume: 39, Issue:2 Topics: Amiodarone; Benzofurans; Heart Diseases; Humans; Syndrome; Triiodothyronine	1978
Amiodarone, nifedipine, sodium cromoglycate. British heart journal, 1991, Volume: 65, Issue:1 Topics: Amiodarone; Cromolyn Sodium; Heart Diseases; Humans; Nifedipine; Plants, Medicinal	1991
[The effectiveness of amiodarone seems to depend highly on the pathology underlying the arrhythmia]. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1990, Volume: 9, Issue:5 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amiodarone; Arrhythmias, Cardiac; Female; Heart Disea	1990
Is amiodarone good for heartburn? Archives of internal medicine, 1990, Volume: 150, Issue:6 Topics: Aged; Amiodarone; Heart Diseases; Heartburn; Humans; Male; Middle Aged	1990
PVCs in the elderly: when to start worrying. Geriatrics, 1985, Volume: 40, Issue:8 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Death, Sudden; Electrocardio	1985
Use of drugs in cardiac rehabilitation. Bibliotheca cardiologica, 1986, Issue:40 Topics: Adrenergic beta-Antagonists; Amiodarone; Diltiazem; Drug Therapy, Combination; Electrocardiography;	1986
The place of amiodarone in cardiology today. Proceedings of a symposium. Heathrow, London, 24-25 October 1985. British journal of clinical practice. Supplement, 1986, Volume: 44 Topics: Amiodarone; Benzofurans; Heart Diseases; Humans	1986
Safety and efficacy of amiodarone. The low-dose perspective. Chest, 1988, Volume: 93, Issue:1 Topics: Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; E	1988
Life-threatening postoperative pulmonary complications in patients with previous amiodarone pulmonary toxicity undergoing cardiothoracic operations. The Journal of thoracic and cardiovascular surgery, 1987, Volume: 93, Issue:6 Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Female; Heart Diseases; Humans; Male; Middle Aged; Postopera	1987
Amiodarone. The Medical letter on drugs and therapeutics, 1986, May-09, Volume: 28, Issue:713 Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Drug Interactions; Heart Diseases; Heart Ventricles;	1986
Plasma amiodarone concentrations during intravenous infusion. British journal of clinical pharmacology, 1986, Volume: 21, Issue:5 Topics: Aged; Amiodarone; Benzofurans; Female; Heart Diseases; Humans; Infusions, Parenteral; Kinetics; Male	1986
Amiodarone. New approaches in the treatment of damaged myocardium. Proceedings of a symposium. Düsseldorf, 11 July, 1984. Drugs, 1985, Volume: 29 Suppl 3 Topics: Amiodarone; Benzofurans; Heart Diseases; Humans	1985
[Electrocardiogram and carotid sphygmogram in prolonged treatment with amiodarone]. Bollettino della Societa italiana di cardiologia, 1973, Volume: 18, Issue:7 Topics: Action Potentials; Adult; Aged; Amiodarone; Benzofurans; Carotid Arteries; Electrocardiography; Fema	1973

amiodarone and Cardiac Diseases

Research Excerpts

Research

Studies (102)

Authors

Clinical Trials (5)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Bardien-Kruger, S	1
Wulff, H	1
Arieff, Z	1
Brink, P	1
Chandy, KG	1
Corfield, V	1
Harb, IA	1
Ashour, H	1
Mostafa, A	1
El Hanbuli, HM	1
Nadwa, EH	1
Barbosa, JMC	1
Pedra Rezende, Y	1
de Melo, TG	1
de Oliveira, G	1
Cascabulho, CM	1
Pereira, ENGDS	1
Daliry, A	1
Salem, KS	1
Samadi Takaldani, AH	1
Negaresh, M	1
Salimi, M	1
Javanshir, N	1
Bachani, N	1
Bera, D	1
Jankharia, B	1
Panicker, GK	1
Lokhandwala, Y	1
Quintana-Villamandos, B	1
Gomez de Diego, JJ	1
Delgado-Martos, MJ	1
Muñoz-Valverde, D	1
Soto-Montenegro, ML	1
Desco, M	1
Delgado-Baeza, E	1
Álvarez, H	1
Mariño, A	1
Valcarce, N	1
Khoo, S	1
Bhagani, S	1
Schapiro, J	1
Llibre, JM	1
Gao, D	1
Van Herendael, H	1
Alshengeiti, L	1
Dorian, P	1
Mangat, I	1
Korley, V	1
Ahmad, K	1
Golovchiner, G	1
Aves, T	1
Pinter, A	1
Osawa, H	1
Muraki, S	1
Sakurada, T	1
Kawaharada, N	1
Sasaki, J	1
Araki, E	1
Nakashima, S	1
Qin, D	1
Leef, G	1
Alam, MB	1
Rattan, R	1
Munir, MB	1
Patel, D	2
Khattak, F	1
Adelstein, E	1
Jain, SK	1
Saba, S	1
Klein, I	2
Danzi, S	1
Tanda, ML	1
Bogazzi, F	3
Martino, E	4
Bartalena, L	2
Tiryakioglu, O	1
Demirtas, S	1
Ari, H	1
Tiryakioglu, SK	1
Huysal, K	1
Selimoglu, O	1
Ozyazicioglu, A	1
Bronzetti, G	1
D'Angelo, C	1
Angelini, A	1
Picchio, FM	1
Boriani, G	1
Lafuente-Lafuente, C	1
Alvarez, JC	1
Leenhardt, A	1
Mouly, S	1
Extramiana, F	1
Caulin, C	1
Funck-Brentano, C	1
Bergmann, JF	1
Orr, CF	1
Ahlskog, JE	1
Amino, M	1
Yoshioka, K	1
Opthof, T	1
Morita, S	1
Uemura, S	1
Tamura, K	1
Fukushima, T	1
Higami, S	1
Otsuka, H	1
Akieda, K	1
Shima, M	1
Fujibayashi, D	1
Hashida, T	1
Inokuchi, S	1
Kodama, I	1
Tanabe, T	1
Nagai, T	1
Satomi, K	2
Noda, T	2
Okamura, H	2
Yamada, Y	2
Shimizu, W	3
Suyama, K	3
Aihara, N	3
Kamakura, S	3
Kurita, T	3
Frankel, DS	1
Mountantonakis, SE	1
Robinson, MR	1
Zado, ES	1
Callans, DJ	1
Marchlinski, FE	1
Golitsyn, SP	1
Wehling, M	1
Mete, O	1
Asa, SL	1
Tomisti, L	1
Materazzi, G	2
Rossi, G	1
Marchello, A	1
Moretti, M	1
De Napoli, L	1
Mariotti, R	1
Miccoli, P	2
Kasprzak, JD	1
Stępińska, J	1
Wożakowska Kapłon, B	1
Drożdż, J	1
Grajek, S	1
Opolski, G	1
Rynkiewicz, A	1
Tykarski, A	1
Filipiak, KJ	1
Bagchi, D	2
Ray, SD	2
Bagchi, M	1
Preuss, HG	1
Stohs, SJ	1
Khan, IA	1
Mehta, NJ	1
Gowda, RM	1
Drucker, MH	1
Smith, I	1
Miracle, VA	1
Hermida, JS	1
Jarry, G	1
Tcheng, E	1
Moullart, V	1
Arlot, S	1
Rey, JL	1
Schvartz, C	1
de Paola, AV	1
Cirenza, C	1
Maciel, RM	1
Fuks, AG	1
Vaisman, M	1
Buescu, A	1
Canivet, JL	1
Yans, T	1
Roediger, L	1
Radermecker, MA	1
Hofmann, R	1
Steinwender, C	1
Kammler, J	1
Kypta, A	1
Wimmer, G	1
Leisch, F	1
Guglin, M	1
Oliveira-Filho, J	1
Viana, LC	1
Vieira-de-Melo, RM	1
Faiçal, F	1
Torreão, JA	1
Villar, FA	1
Reis, FJ	1
Janko, S	1
Hoffmann, E	1
Berti, P	1
Ambrosini, CE	1
Carrió, ML	1
Fortià, C	1
Javierre, C	1
Rodríguez, D	1
Farrero, E	1
Castells, E	1
Ventura, JL	1
Aiba, T	2
Yamagata, K	1
Taguchi, A	2
Giorgetti, C	1
Danisi, M	1
Viti, V	1
Barsotti, GP	1
Pratali, MC	1
Pellissier, JF	1
Pouget, J	1
Cros, D	1
De Victor, B	1
Serratrice, G	1
Toga, M	1
Politi, A	1
Poggio, G	1
Margiotta, A	1
Safran, M	1
Aghini-Lombardi, F	1
Rajatanavin, R	1
Lenziardi, M	1
Fay, M	1
Pacchiarotti, A	1
Aronin, N	1
Macchia, E	1
Haffajee, C	1
Goedel-Meinen, L	1
Schmidt, G	1
Wirtzfeld, A	1
Jahns, G	1
Klein, G	1
Böttger, I	1
Ulm, K	1
Baedeker, W	1
Trobaugh, GB	1
Kudenchuk, PJ	1
Greene, HL	1
Tutt, RC	1
Kingston, E	1
Gorham, JR	1
Gross, BW	1
Graham, EL	1
Sears, GK	1
Werner, JA	1
Fornaro, G	1
Rossi, P	1
Padrini, R	1
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de Castro, JJ	1
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Ferrero, C	1