amiodarone has been researched along with Cancer of Lung in 28 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our aim was to estimate the costs and health benefits of routinely administered postoperative amiodarone as a prophylactic agent in reducing the risk of atrial fibrillation in patients undergoing surgery for lung cancer." | 9.19 | Amiodarone is a cost-neutral way of preventing atrial fibrillation after surgery for lung cancer. ( Christensen, TD; Pilegaard, HK; Riber, LP, 2014) |
| "The patients in the amiodarone prophylaxis group had a reduction in the risk of atrial fibrillation of 23% (12 to 31); number needed to treat was 4." | 9.16 | Amiodarone significantly decreases atrial fibrillation in patients undergoing surgery for lung cancer. ( Christensen, TD; Hoejsgaard, A; Jensen, HK; Pilegaard, HK; Riber, LP, 2012) |
| "Our aim was to estimate the costs and health benefits of routinely administered postoperative amiodarone as a prophylactic agent in reducing the risk of atrial fibrillation in patients undergoing surgery for lung cancer." | 5.19 | Amiodarone is a cost-neutral way of preventing atrial fibrillation after surgery for lung cancer. ( Christensen, TD; Pilegaard, HK; Riber, LP, 2014) |
| "The patients in the amiodarone prophylaxis group had a reduction in the risk of atrial fibrillation of 23% (12 to 31); number needed to treat was 4." | 5.16 | Amiodarone significantly decreases atrial fibrillation in patients undergoing surgery for lung cancer. ( Christensen, TD; Hoejsgaard, A; Jensen, HK; Pilegaard, HK; Riber, LP, 2012) |
| "Atypical manifestations of pulmonary toxicity and previously unreported autonomic nervous system dysfunction complicating amiodarone therapy were observed in a patient being treated for sustained ventricular tachycardia." | 4.77 | Atypical pulmonary and neurologic complications of amiodarone in the same patient. Report of a case and review of the literature. ( Estes, NA; Mack, KD; Manolis, AS; Tordjman, T, 1987) |
| "Amiodarone is an effective agent in the treatment of life-threatening ventricular arrhythmias." | 3.67 | Amiodarone-induced pulmonary mass. ( Faber, LP; Piccione, W; Rosenberg, MS, 1989) |
| " Amiodarone is both safe and effective in establishing sinus rhythm." | 2.71 | Is amiodarone a safe antiarrhythmic to use in supraventricular tachyarrhythmias after lung cancer surgery? ( Barbetakis, N; Vassiliadis, M, 2004) |
| "A radiograph demonstrated pulmonary edema; echocardiography revealed an ostium secundum atrial septal defect with increased flow to the lung and severe pulmonary hypertension." | 1.37 | [Postoperative management of postpneumonectomy pulmonary edema in a patient with ostium secundum atrial septal defect]. ( Barberá, M; Marchante, M; Navarro, JL; Ramos, F; Vicente, R, 2011) |
| "Based on this case amiodarone-related pneumonitis will be discussed, which due to a lack of pathognomonic symptoms is often difficult to diagnose and for which there are few treatment options available." | 1.35 | [Amiodarone-induced pneumonitis. Lethal complication in a patient after thoracic surgery]. ( Fisseler-Eckhoff, A; Ghezel-Ahmadi, V; Kürschner, VC; Obenhaus, T; Schirren, J; Schmitz, JE, 2008) |
| "Amiodarone is an anti-arrhythmic drug for life-threatening tachycardia, but various adverse effects have been reported." | 1.35 | Amiodarone-related pulmonary mass and unique membranous glomerulonephritis in a patient with valvular heart disease: Diagnostic pitfall and new findings. ( Katayama, T; Kimura, T; Kuramochi, S; Okada, Y; Ueda, Y; Yamada, T; Yoshikawa, T, 2008) |
| "Amiodarone was administered to those who developed SA with a loading dose of 5 mg/kg in 30 min and a maintenance dose of 15 mg/kg in 24 h." | 1.31 | Supraventricular arrhythmia following lung resection for non-small cell lung cancer and its treatment with amiodarone. ( Canneto, B; Ciriaco, P; Mazzone, P; Zannini, P, 2000) |
| " However, in this patient, effective control of the arrhythmia was achieved with a moderate dosage of oral amiodarone (600 mg daily for 4 weeks, then 400 mg daily), and he had no further episodes of presyncope." | 1.30 | Amiodarone for control of recurrent ventricular tachycardia secondary to cardiac metastasis. ( Leak, D, 1998) |
| "Fourteen patients with Adr-resistant tumors were treated with Adr and AM." | 1.28 | In vitro and in vivo modulation of multi-drug resistance with amiodarone. ( de Vries, EG; Meijer, C; Mulder, NH; Mulder, PO; Nanninga, AG; Uges, DR; van der Graaf, WT; Vellenga, E, 1991) |
| "The authors studied 13 cases of arrhythmia following pneumonectomy in a series of 94 pneumonectomies performed in the Thoracic Surgery Unit." | 1.27 | [Cardiac rhythm disorders after pneumonectomy]. ( Debesse, B; Dumouchel, A; Hubsch, JP; Zukerman, C, 1985) |
| "Amiodarone may cause pulmonary toxicity mimicking metastatic lung disease." | 1.27 | Amiodarone-induced pulmonary toxicity mimicking metastatic lung disease. ( Honeybourne, D; Patel, P; Watson, RD, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.86) | 18.7374 |
| 1990's | 5 (17.86) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 9 (32.14) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Bognar, Z | 1 |
| Cseh, AM | 1 |
| Fekete, K | 1 |
| Antus, C | 1 |
| Bognar, R | 1 |
| Tapodi, A | 1 |
| Ramadan, FHJ | 1 |
| Sumegi, B | 1 |
| Gallyas, F | 1 |
| López Brunsó, M | 1 |
| Toro Blanch, C | 1 |
| Sais Girona, E | 1 |
| Roa García, D | 1 |
| Hernández Martínez, A | 1 |
| Izquierdo Font, A | 1 |
| Guerra Prió, S | 1 |
| Mas Pueyo, HG | 1 |
| Bosch-Barrera, J | 1 |
| Haraldsdottir, S | 1 |
| Li, Q | 1 |
| Villalona-Calero, MA | 1 |
| Olencki, TE | 1 |
| Kendra, K | 1 |
| Ing, SW | 1 |
| Riber, LP | 3 |
| Christensen, TD | 3 |
| Pilegaard, HK | 3 |
| Patel, AJ | 1 |
| Hunt, I | 1 |
| Mitrakas, AG | 1 |
| Kalamida, D | 1 |
| Koukourakis, MI | 1 |
| Ghezel-Ahmadi, V | 1 |
| Kürschner, VC | 1 |
| Fisseler-Eckhoff, A | 1 |
| Schirren, J | 1 |
| Schmitz, JE | 1 |
| Obenhaus, T | 1 |
| Kimura, T | 1 |
| Kuramochi, S | 1 |
| Katayama, T | 1 |
| Yoshikawa, T | 1 |
| Yamada, T | 1 |
| Ueda, Y | 1 |
| Okada, Y | 1 |
| Tisdale, JE | 1 |
| Wroblewski, HA | 1 |
| Wall, DS | 1 |
| Rieger, KM | 1 |
| Hammoud, ZT | 1 |
| Young, JV | 1 |
| Kesler, KA | 1 |
| Marchante, M | 1 |
| Ramos, F | 1 |
| Vicente, R | 1 |
| Navarro, JL | 1 |
| Barberá, M | 1 |
| Liyanage, UA | 1 |
| Rajapakse, T | 1 |
| Somaratne, SC | 1 |
| Gunaratne, PS | 1 |
| Jensen, HK | 1 |
| Hoejsgaard, A | 1 |
| Barbetakis, N | 1 |
| Vassiliadis, M | 1 |
| Uhal, BD | 2 |
| Zhang, H | 1 |
| Abdul-Hafez, A | 1 |
| Shu, R | 1 |
| Li, X | 1 |
| Jarand, J | 1 |
| Lee, A | 1 |
| Leigh, R | 1 |
| Costa-Jussà, FR | 1 |
| Corrin, B | 1 |
| Jacobs, JM | 1 |
| van der Graaf, WT | 2 |
| de Vries, EG | 2 |
| Timmer-Bosscha, H | 1 |
| Meersma, GJ | 1 |
| Mesander, G | 1 |
| Vellenga, E | 2 |
| Mulder, NH | 2 |
| Chai, JL | 1 |
| Patz, EF | 1 |
| Douchet, MP | 1 |
| Barsotti, P | 1 |
| Schneeberger, M | 1 |
| Bauer, C | 1 |
| Massard, G | 1 |
| Brechenmacher, C | 1 |
| Wihlm, JM | 1 |
| Leak, D | 1 |
| Bargout, R | 1 |
| Jankov, A | 1 |
| Dincer, E | 1 |
| Wang, R | 1 |
| Komodromos, T | 1 |
| Ibarra-Sunga, O | 1 |
| Filippatos, G | 1 |
| Ciriaco, P | 1 |
| Mazzone, P | 1 |
| Canneto, B | 1 |
| Zannini, P | 1 |
| Uges, DR | 1 |
| Nanninga, AG | 1 |
| Meijer, C | 1 |
| Mulder, PO | 1 |
| Zukerman, C | 1 |
| Hubsch, JP | 1 |
| Dumouchel, A | 1 |
| Debesse, B | 1 |
| Piccione, W | 1 |
| Faber, LP | 1 |
| Rosenberg, MS | 1 |
| Manolis, AS | 1 |
| Tordjman, T | 1 |
| Mack, KD | 1 |
| Estes, NA | 1 |
| Patel, P | 1 |
| Honeybourne, D | 1 |
| Watson, RD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevention of Atrial Fibrillation Following Noncardiac Thoracic Surgery[NCT00127712] | Phase 4 | 130 participants (Actual) | Interventional | 2004-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00127712)
Timeframe: 7 days
| Intervention | Participants (Number) |
|---|---|
| Amiodarone | 9 |
| Control | 22 |
(NCT00127712)
Timeframe: 7 days
| Intervention | participants (Number) |
|---|---|
| Amiodarone | 9 |
| Control | 21 |
(NCT00127712)
Timeframe: Duration of hospitalization
| Intervention | Days (Median) |
|---|---|
| Amiodarone | 7 |
| Control | 8 |
(NCT00127712)
Timeframe: Duration of hospitalization
| Intervention | Hours (Median) |
|---|---|
| Amiodarone | 46 |
| Control | 84 |
2 reviews available for amiodarone and Cancer of Lung
| Article | Year |
|---|---|
[Supraventricular arrhythmia after pneumonectomy. Apropos of 100 cases and review of the literature].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Lung Neoplasms; Male; | 1998 |
Atypical pulmonary and neurologic complications of amiodarone in the same patient. Report of a case and review of the literature.
Topics: Aged; Amiodarone; Autonomic Nervous System Diseases; Diagnosis, Differential; Female; Humans; Hypote | 1987 |
4 trials available for amiodarone and Cancer of Lung
| Article | Year |
|---|---|
Amiodarone is a cost-neutral way of preventing atrial fibrillation after surgery for lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Denmark; Fe | 2014 |
A randomized trial evaluating amiodarone for prevention of atrial fibrillation after pulmonary resection.
Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Carcinoma, Non- | 2009 |
Amiodarone significantly decreases atrial fibrillation in patients undergoing surgery for lung cancer.
Topics: Aged; Aged, 80 and over; Amiodarone; Atrial Fibrillation; Double-Blind Method; Female; Humans; Lung | 2012 |
Is amiodarone a safe antiarrhythmic to use in supraventricular tachyarrhythmias after lung cancer surgery?
Topics: Adult; Age Distribution; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Huma | 2004 |
22 other studies available for amiodarone and Cancer of Lung
| Article | Year |
|---|---|
Amiodarone's major metabolite, desethylamiodarone inhibits proliferation of B16-F10 melanoma cells and limits lung metastasis formation in an in vivo experimental model.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cel | 2020 |
Probable drug-drug interaction between erlotinib and amiodarone causes severe neurotoxicity in a patient with advanced lung cancer.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Non-Small-Cell Lung; | 2018 |
Case of sorafenib-induced thyroid storm.
Topics: Adrenal Gland Neoplasms; Aged; Amiodarone; Anti-Arrhythmia Agents; Antineoplastic Agents; Atrial Fib | 2013 |
Reply to Patel and Hunt.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Lung Neoplasms; Male | 2015 |
The evidence for routine anti-arrhythmic prophylaxis in patients undergoing pulmonary resection surgery.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Lung Neoplasms; Male | 2015 |
Effect of mitochondrial metabolism-interfering agents on cancer cell mitochondrial function and radio/chemosensitivity.
Topics: Amiodarone; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Docetaxel; Drug Resis | 2014 |
[Amiodarone-induced pneumonitis. Lethal complication in a patient after thoracic surgery].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Carcinoma, Non-Small-Cell Lung; Diagnosis, Differential; F | 2008 |
Amiodarone-related pulmonary mass and unique membranous glomerulonephritis in a patient with valvular heart disease: Diagnostic pitfall and new findings.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cytoplasm; Diagnostic Errors; Fatal Outcome; Foam Cells; G | 2008 |
[Postoperative management of postpneumonectomy pulmonary edema in a patient with ostium secundum atrial septal defect].
Topics: Adenocarcinoma; Amiodarone; Bundle-Branch Block; Combined Modality Therapy; Diuretics; Electric Coun | 2011 |
An unusual manifestation of amiodarone toxicity: lung mass mimicking a lung carcinoma.
Topics: Aged; Amiodarone; Biopsy, Fine-Needle; Humans; Lung; Lung Diseases; Lung Neoplasms; Male; Myocardial | 2011 |
Amiodarone induces angiotensinogen gene expression in lung alveolar epithelial cells through activation protein-1.
Topics: Adenocarcinoma; Amiodarone; Angiotensins; Anti-Arrhythmia Agents; Base Sequence; Binding Sites; Cell | 2007 |
Amiodaronoma: an unusual form of amiodarone-induced pulmonary toxicity.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Female; Humans; Lung Diseases; Lu | 2007 |
Amiodarone lung toxicity: a human and experimental study.
Topics: Adult; Amiodarone; Animals; Benzofurans; Humans; Lung; Lung Neoplasms; Lymphatic Diseases; Male; Mic | 1984 |
Effects of amiodarone, cyclosporin A, and PSC 833 on the cytotoxicity of mitoxantrone, doxorubicin, and vincristine in non-P-glycoprotein human small cell lung cancer cell lines.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cyclospo | 1994 |
CT of the lung: patterns of calcification and other high-attenuation abnormalities.
Topics: Amiodarone; Calcinosis; Contrast Media; Humans; Lung Diseases; Lung Neoplasms; Pulmonary Fibrosis; T | 1994 |
Amiodarone for control of recurrent ventricular tachycardia secondary to cardiac metastasis.
Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Carcinoma, Squamous Cell; Heart Neop | 1998 |
Amiodarone induces apoptosis of human and rat alveolar epithelial cells in vitro.
Topics: Adenocarcinoma; Amino Acid Chloromethyl Ketones; Amiodarone; Angiotensin-Converting Enzyme Inhibitor | 2000 |
Supraventricular arrhythmia following lung resection for non-small cell lung cancer and its treatment with amiodarone.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Carcinoma, Non-Small-Cell Lung; | 2000 |
In vitro and in vivo modulation of multi-drug resistance with amiodarone.
Topics: Adult; Amiodarone; Biological Transport; Carcinoma, Small Cell; Cell Line; Cell Survival; Colonic Ne | 1991 |
[Cardiac rhythm disorders after pneumonectomy].
Topics: Adenocarcinoma; Adult; Aged; Aging; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Carcinoma | 1985 |
Amiodarone-induced pulmonary mass.
Topics: Amiodarone; Arrhythmias, Cardiac; Diagnosis, Differential; Humans; Lung Diseases; Lung Neoplasms; Ma | 1989 |
Amiodarone-induced pulmonary toxicity mimicking metastatic lung disease.
Topics: Aged; Amiodarone; Diagnosis, Differential; Humans; Lung Diseases; Lung Neoplasms; Male; Radiography | 1987 |