Page last updated: 2024-10-22

amiodarone and Brugada Syndrome

amiodarone has been researched along with Brugada Syndrome in 10 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Brugada Syndrome: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.

Research Excerpts

ExcerptRelevanceReference
"Cardiac disorders caused by sofosbuvir are liable to be worsened by concomitant use of one of the many drugs that provoke cardiac arrhythmia."7.81Sofosbuvir + amiodarone: bradycardia and conduction disturbances. ( , 2015)
"Cardiac disorders caused by sofosbuvir are liable to be worsened by concomitant use of one of the many drugs that provoke cardiac arrhythmia."3.81Sofosbuvir + amiodarone: bradycardia and conduction disturbances. ( , 2015)
"Although amiodarone appears to have few pro-arrhythmic effects, torsade de pointes (TdP) has been observed after administration of a low dose and short term use of oral amiodarone, in the absence of predisposing factors."3.80Intermittent QT prolongation induced by short-term oral amiodarone therapy. ( Amasyalı, B; Astarcioglu, MA; Durmuş, HI; Sen, T, 2014)
"The amiodarone was stopped 3 weeks later as she was pregnant."1.38Oral amiodarone provoking inferior ST elevation and unmasking Brugada-like electrocardiogram feature. ( Braganza, D; Jassam, Y; Lee, CW; Virdee, M, 2012)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Aleksandrowicz, D1
Robinson, D1
Hand, G1
Ausman, J1
Hackett, A1
Astarcioglu, MA1
Durmuş, HI1
Sen, T1
Amasyalı, B1
Zhang, X1
Beebe, T1
Jen, N1
Lee, CA1
Tai, Y1
Hsiai, TK1
Lee, CW1
Jassam, Y1
Braganza, D1
Virdee, M1
Yaşar Bilge, NS1
Gönüllü, E1
Kaşifoğlu, T1
Korkmaz, C1
Joshi, S1
Raiszadeh, F1
Pierce, W1
Steinberg, JS1
Tsukada, YT1
Kishida, H1
Nägele, H1
Behrens, S1
Castel, A1

Reviews

1 review available for amiodarone and Brugada Syndrome

ArticleYear
[Adverse effects of cardiovascular agents].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Brugada Syndrome; Drug Interactions; Fibrinolyti

2007

Other Studies

9 other studies available for amiodarone and Brugada Syndrome

ArticleYear
Amiodarone or lidocaine, that is the question - Pharmacological therapy of refractory ventricular fibrillation associated with Brugada syndrome.
    Resuscitation, 2021, Volume: 169

    Topics: Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Humans; Lidocaine; Ventricular Fibrillation

2021
Brugada pattern exposed with administration of amiodarone during emergent treatment of ventricular tachycardia.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:2

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Defibrillators, Implantable; Electrocar

2019
Intermittent QT prolongation induced by short-term oral amiodarone therapy.
    Kardiologia polska, 2014, Volume: 72, Issue:2

    Topics: Administration, Oral; Adult; Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Cardiac Conductio

2014
Flexible and waterproof micro-sensors to uncover zebrafish circadian rhythms: The next generation of cardiac monitoring for drug screening.
    Biosensors & bioelectronics, 2015, Sep-15, Volume: 71

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biosensing Techniques; Brugada Sy

2015
Sofosbuvir + amiodarone: bradycardia and conduction disturbances.
    Prescrire international, 2015, Volume: 24, Issue:166

    Topics: Amiodarone; Anti-Arrhythmia Agents; Antiviral Agents; Arrhythmias, Cardiac; Bradycardia; Brugada Syn

2015
Oral amiodarone provoking inferior ST elevation and unmasking Brugada-like electrocardiogram feature.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2012, Volume: 14, Issue:7

    Topics: Administration, Oral; Adult; Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiograp

2012
Amiodarone-induced pleural fluid is not always accompanied by a risk factor.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2012, Volume: 12, Issue:3

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Defibrillators, Implantable; Humans; Ma

2012
Antiarrhythmic induced electrical storm in Brugada syndrome: a case report.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2007, Volume: 12, Issue:3

    Topics: Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Defibrillators, Impl

2007
Ventricular tachycardia and aggravation of Brugada ECG pattern in a patient with coronary artery disease and combined amiodarone and betablocker therapy.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2008, Volume: 97, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Coronary Ar

2008