Page last updated: 2024-10-22

amiodarone and Arteriosclerosis, Coronary

amiodarone has been researched along with Arteriosclerosis, Coronary in 25 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Research Excerpts

ExcerptRelevanceReference
"Sotalol is a commonly prescribed antiarrhythmic drug (AAD) used for maintaining sinus rhythm in patients with atrial fibrillation (AF)."9.19Comparison of safety of sotalol versus amiodarone in patients with atrial fibrillation and coronary artery disease. ( Al-Khatib, SM; Allen-LaPointe, N; Anstrom, KJ; Daubert, JP; DeWald, T; Horton, JR; Lokhnygina, Y; Peterson, ED; Piccini, JP; Shaw, LK; Steinberg, BA; Thomas, K; Wojdyla, DM, 2014)
"We studied the use of perioperative IV and oral administration of amiodarone for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass graft surgery (CABG)."9.11Giving IV and oral amiodarone perioperatively for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery: the GAP study. ( Hollander, G; Kerstein, J; Lichstein, E; Majid, M; Qamar, M; Shani, J; Soodan, A, 2004)
"Amiodarone is one of the most efficient and safe antiarrhythmic drugs in the treatment of atrial fibrillation (AF)."7.73"Torsade de pointes" in patients with structural heart disease and atrial fibrillation treated with amiodarone, beta-blockers, and digitalis. ( Bitzen, A; Lewalter, T; Lüderitz, B; Schrickel, JW; Schwab, JO; Yang, A, 2006)
"Although amiodarone appears to have few pro-arrhythmic effects, torsade de pointes (TdP) has been observed during long-term drug administration, usually in conjunction with electrolyte disturbances, a change in drug dosage, or concomitant drug therapy."7.73Torsade de pointes induced by short-term oral amiodarone therapy. ( Ahn, JC; Kim, YH; Lim, HE; Pak, HN; Song, WH, 2006)
"No sustained ventricular tachycardia, ventricular fibrillation, sudden cardiac death, or cardiovascular mortality were observed."5.72Propafenone use in coronary artery disease patients undergoing atrial fibrillation ablation. ( Aksu, T; Aras, D; Cay, S; Kara, M; Ozcan, F; Ozeke, O; Topaloglu, S, 2022)
"Sotalol is a commonly prescribed antiarrhythmic drug (AAD) used for maintaining sinus rhythm in patients with atrial fibrillation (AF)."5.19Comparison of safety of sotalol versus amiodarone in patients with atrial fibrillation and coronary artery disease. ( Al-Khatib, SM; Allen-LaPointe, N; Anstrom, KJ; Daubert, JP; DeWald, T; Horton, JR; Lokhnygina, Y; Peterson, ED; Piccini, JP; Shaw, LK; Steinberg, BA; Thomas, K; Wojdyla, DM, 2014)
"We studied the use of perioperative IV and oral administration of amiodarone for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass graft surgery (CABG)."5.11Giving IV and oral amiodarone perioperatively for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery: the GAP study. ( Hollander, G; Kerstein, J; Lichstein, E; Majid, M; Qamar, M; Shani, J; Soodan, A, 2004)
"We enrolled all consecutive patients with unsuccessful/not feasible catheter ablation and ineffective/contraindicated amiodarone or beta-blockers, which started the mexiletine treatment for refractory ventricular tachycardia (VT) or ventricular fibrillation (VF) between January 2010 and January 2020."4.12Mexiletine for ventricular arrhythmias in patients with chronic coronary syndrome: a cohort study. ( Bilato, C; Cavedon, S; Mecenero, A; Mugnai, G; Paolini, C; Perrone, C, 2022)
"We evaluated the hypothesis that a relationship exists between inflammation and the outcome of pharmaceutical cardioversion with amiodarone in recent onset atrial fibrillation."3.74Interleukin-2 serum levels variations in recent onset atrial fibrillation are related with cardioversion outcome. ( Dragomanovits, S; Kalogeropoulos, AS; Kremastinos, DT; Papathanasiou, S; Rigopoulos, AG; Rizos, I; Sakadakis, EA; Tsiodras, S, 2007)
"Amiodarone is one of the most efficient and safe antiarrhythmic drugs in the treatment of atrial fibrillation (AF)."3.73"Torsade de pointes" in patients with structural heart disease and atrial fibrillation treated with amiodarone, beta-blockers, and digitalis. ( Bitzen, A; Lewalter, T; Lüderitz, B; Schrickel, JW; Schwab, JO; Yang, A, 2006)
"Although amiodarone appears to have few pro-arrhythmic effects, torsade de pointes (TdP) has been observed during long-term drug administration, usually in conjunction with electrolyte disturbances, a change in drug dosage, or concomitant drug therapy."3.73Torsade de pointes induced by short-term oral amiodarone therapy. ( Ahn, JC; Kim, YH; Lim, HE; Pak, HN; Song, WH, 2006)
"Amiodarone is a class III antiarrhythmic drug containing 37% iodine by weight, with a structure similar to that of thyroid hormones."2.72Evaluation and Treatment of Amiodarone-Induced Thyroid Disorders. ( Burman, KD; Wartofsky, L; Ylli, D, 2021)
"No sustained ventricular tachycardia, ventricular fibrillation, sudden cardiac death, or cardiovascular mortality were observed."1.72Propafenone use in coronary artery disease patients undergoing atrial fibrillation ablation. ( Aksu, T; Aras, D; Cay, S; Kara, M; Ozcan, F; Ozeke, O; Topaloglu, S, 2022)
"Polymorphic ventricular tachycardia (VT) without QT prolongation is well described in patients without structural heart disease (mainly idiopathic ventricular fibrillation and Brugada syndrome) and in patients with acute ST-elevation myocardial infarction."1.51Quinidine-Responsive Polymorphic Ventricular Tachycardia in Patients With Coronary Heart Disease. ( Amit, G; Asher, E; Belhassen, B; Chorin, E; Halkin, A; Havakuk, O; Hochstadt, A; Laish-Farkash, A; Lee, JK; Rosso, R; Tovia-Brodie, O; Viskin, D; Viskin, S, 2019)
"Amiodarone is a widely used and very potent antiarrhythmic substance."1.39Amiodarone-induced pulmonary toxicity--a fatal case report and literature review. ( Breithardt, G; Buerke, B; Hilker, E; Lebiedz, P; Range, FT, 2013)
"Bidirectional ventricular tachycardia (BVT) is an uncommon type of polymorphic ventricular tachycardia (PVT) with alternating polarity of the QRS complex most commonly described digitalis toxicity."1.38Bidirectional ventricular tachycardia due to coronary allograft vasculopathy a unique presentation. ( Bhavnani, SP; Clyne, CA, 2012)
"As the population ages, recurrent ventricular tachycardia (VT) is increasingly encountered in elderly patients with ischemic heart disease."1.36Mortality and safety of catheter ablation for antiarrhythmic drug-refractory ventricular tachycardia in elderly patients with coronary artery disease. ( Inada, K; Koplan, BA; Roberts-Thomson, KC; Seiler, J; Steven, D; Stevenson, WG; Tedrow, UB, 2010)
"Amiodarone is a very effective antiarrhytmic drug."1.34Hyperglobulinemia in amiodarone-induced pneumonitis. ( Antipov, N; Farfel, Z; Mayan, H; Mouallem, M; Sela, BA, 2007)
"Amiodarone tissue uptake was quantified by high-performance liquid chromatography, and xanthine oxidase-dependent superoxide anion formation was investigated in vitro in presence or absence of amiodarone."1.34Antioxidant activity and sex differences of acute vascular effects of amiodarone in advanced atherosclerosis. ( Barton, M; Bhattacharya, I; Fojtu, E; Ha, HR; Jochum, W; Keller, M; Lang, M; Mundy, AL; Traupe, T, 2007)
"Amiodarone or sotalol was used in all postoperative patients for 6 months, except in 8 who had bradycardia."1.33Ablation of atrial fibrillation using microwave energy--early experience. ( Hamzeh, K; Jamil, H; Kabbani, SS; Murad, G; Sabbagh, A, 2005)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's1 (4.00)18.2507
2000's10 (40.00)29.6817
2010's10 (40.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Cay, S1
Kara, M1
Ozcan, F1
Ozeke, O1
Aksu, T1
Aras, D1
Topaloglu, S1
Ylli, D1
Wartofsky, L1
Burman, KD1
Mugnai, G1
Paolini, C1
Cavedon, S1
Mecenero, A1
Perrone, C1
Bilato, C1
Elnaggar, MN1
Jbeili, K1
Nik-Hussin, N1
Kozhippally, M1
Pappachan, JM1
Viskin, S1
Chorin, E1
Viskin, D1
Hochstadt, A1
Halkin, A1
Tovia-Brodie, O1
Lee, JK1
Asher, E1
Laish-Farkash, A1
Amit, G1
Havakuk, O1
Belhassen, B1
Rosso, R1
Plechev, VV1
Zagidullin, ShZ1
Iunusov, VM1
Zubareva, IG1
Nikolaeva, IE1
Passaloglou, IT1
Sabashnikov, A1
Zeriouh, M1
Reutter, S1
Fatullayev, J1
Choi, YH1
Wahlers, T1
Piccini, JP1
Al-Khatib, SM1
Wojdyla, DM1
Shaw, LK1
Horton, JR1
Lokhnygina, Y1
Anstrom, KJ1
DeWald, T1
Allen-LaPointe, N1
Steinberg, BA1
Thomas, K1
Daubert, JP1
Peterson, ED1
Nouri, SN1
Block, BL1
Zebis, LR1
Christensen, TD1
Thomsen, HF1
Hjortdal, VE1
Inada, K1
Roberts-Thomson, KC1
Seiler, J1
Steven, D1
Tedrow, UB1
Koplan, BA1
Stevenson, WG1
Bhavnani, SP1
Clyne, CA1
Farooq, V1
Serruys, PW1
Bourantas, C1
Vranckx, P1
Diletti, R1
Garcia Garcia, HM1
Holmes, DR1
Kappetein, AP1
Mack, M1
Feldman, T1
Morice, MC1
Colombo, A1
Morel, MA1
de Vries, T1
van Es, GA1
Steyerberg, EW1
Dawkins, KD1
Mohr, FW1
James, S1
Ståhle, E1
Range, FT1
Hilker, E1
Breithardt, G1
Buerke, B1
Lebiedz, P1
Kerstein, J1
Soodan, A1
Qamar, M1
Majid, M1
Lichstein, E1
Hollander, G1
Shani, J1
Kabbani, SS1
Murad, G1
Jamil, H1
Sabbagh, A1
Hamzeh, K1
Schrickel, JW1
Schwab, JO1
Yang, A1
Bitzen, A1
Lüderitz, B1
Lewalter, T1
Lim, HE1
Pak, HN1
Ahn, JC1
Song, WH1
Kim, YH1
Minhaj, MM1
Zvara, DA1
Nayyar, P1
Maslow, A1
Mouallem, M1
Antipov, N1
Mayan, H1
Sela, BA1
Farfel, Z1
Rizos, I1
Tsiodras, S1
Rigopoulos, AG1
Dragomanovits, S1
Kalogeropoulos, AS1
Papathanasiou, S1
Sakadakis, EA1
Kremastinos, DT1
Traupe, T1
Keller, M1
Fojtu, E1
Bhattacharya, I1
Lang, M1
Ha, HR1
Jochum, W1
Mundy, AL1
Barton, M1
Nägele, H1
Behrens, S1
Castel, A1
Tanttula, K1
Pappinen, H1
Hämäläinen, P1
Lupanov, VP1
Sidorenko, BA1
Nekrutman, EA1
Kulikova, TV1
Podinovskaia, IaA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Synergy Between PCI With TAXUS and Cardiac Surgery: SYNTAX Extended Survival[NCT03417050]2,636 participants (Actual)Observational2016-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amiodarone and Arteriosclerosis, Coronary

ArticleYear
Evaluation and Treatment of Amiodarone-Induced Thyroid Disorders.
    The Journal of clinical endocrinology and metabolism, 2021, 01-01, Volume: 106, Issue:1

    Topics: Albania; Amiodarone; Arrhythmias, Cardiac; Coronary Artery Disease; Humans; Male; Middle Aged; Myoca

2021
Amiodarone-Induced Thyroid Dysfunction: A Clinical Update.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2018, Volume: 126, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Chest Pain; Coronary Artery Disease; Humans; Male; Middle Aged;

2018

Trials

4 trials available for amiodarone and Arteriosclerosis, Coronary

ArticleYear
Comparison of safety of sotalol versus amiodarone in patients with atrial fibrillation and coronary artery disease.
    The American journal of cardiology, 2014, Sep-01, Volume: 114, Issue:5

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cause of Death; Coronary Artery Disea

2014
Amiodarone protects diabetics and non-diabetics undergoing coronary artery bypass grafting equally.
    Scandinavian cardiovascular journal : SCJ, 2008, Volume: 42, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Coronary Arte

2008
Incidence and multivariable correlates of long-term mortality in patients treated with surgical or percutaneous revascularization in the synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) trial.
    European heart journal, 2012, Volume: 33, Issue:24

    Topics: Aged; Amiodarone; Coronary Artery Bypass; Coronary Artery Disease; Female; Gastrointestinal Hemorrha

2012
Giving IV and oral amiodarone perioperatively for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery: the GAP study.
    Chest, 2004, Volume: 126, Issue:3

    Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Case-Control St

2004

Other Studies

19 other studies available for amiodarone and Arteriosclerosis, Coronary

ArticleYear
Propafenone use in coronary artery disease patients undergoing atrial fibrillation ablation.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022, Volume: 65, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Disease; Death, Sudden, Car

2022
Mexiletine for ventricular arrhythmias in patients with chronic coronary syndrome: a cohort study.
    Acta cardiologica, 2022, Volume: 77, Issue:3

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Cohort Studies; Coronary Artery Disease

2022
Quinidine-Responsive Polymorphic Ventricular Tachycardia in Patients With Coronary Heart Disease.
    Circulation, 2019, 05-14, Volume: 139, Issue:20

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Disease; Drug Evaluation; Drug Resistance;

2019
[Prophylactic use of VFS in patients with coronary artery disease in the perioperative coronary artery bypass grafting].
    Kardiologiia, 2013, Volume: 53, Issue:8

    Topics: Aconitine; Amiodarone; Anti-Arrhythmia Agents; Chemoprevention; Comparative Effectiveness Research;

2013
Rapid diagnostics and treatment of early complications after CABG surgery: a life saver.
    The heart surgery forum, 2013, Volume: 16, Issue:6

    Topics: Aged; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Bypass; Coronary Artery Disease;

2013
Triple Oral Antithrombotic Therapy: A Teachable Moment.
    JAMA internal medicine, 2016, 10-01, Volume: 176, Issue:10

    Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chest Pain; Coronary Artery Disease; Drug-Elu

2016
Mortality and safety of catheter ablation for antiarrhythmic drug-refractory ventricular tachycardia in elderly patients with coronary artery disease.
    Heart rhythm, 2010, Volume: 7, Issue:6

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Amiodarone; Anti-Arrhythmia Agents; Body Surface Pot

2010
Bidirectional ventricular tachycardia due to coronary allograft vasculopathy a unique presentation.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2012, Volume: 17, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Disease; Defibrillators, Implantable; Drug-Eluti

2012
Amiodarone-induced pulmonary toxicity--a fatal case report and literature review.
    Cardiovascular drugs and therapy, 2013, Volume: 27, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Disease; Drug Overdose; Fatal Outcome; Hal

2013
Ablation of atrial fibrillation using microwave energy--early experience.
    Asian cardiovascular & thoracic annals, 2005, Volume: 13, Issue:3

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Coronary Ar

2005
"Torsade de pointes" in patients with structural heart disease and atrial fibrillation treated with amiodarone, beta-blockers, and digitalis.
    Pacing and clinical electrophysiology : PACE, 2006, Volume: 29, Issue:4

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Arter

2006
Torsade de pointes induced by short-term oral amiodarone therapy.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2006, Volume: 8, Issue:12

    Topics: Administration, Oral; Adult; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillat

2006
Case 1-2007 morbidly obese patient undergoing cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 2007, Volume: 21, Issue:1

    Topics: Amiodarone; Anesthesia, General; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Catheterizatio

2007
Hyperglobulinemia in amiodarone-induced pneumonitis.
    Cardiovascular drugs and therapy, 2007, Volume: 21, Issue:1

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Disease; Female; Humans

2007
Interleukin-2 serum levels variations in recent onset atrial fibrillation are related with cardioversion outcome.
    Cytokine, 2007, Volume: 40, Issue:3

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; C-Reactive Protein

2007
Antioxidant activity and sex differences of acute vascular effects of amiodarone in advanced atherosclerosis.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:5

    Topics: Acetylcholine; Amiodarone; Animals; Antioxidants; Aorta; Apolipoproteins E; Coronary Artery Disease;

2007
Ventricular tachycardia and aggravation of Brugada ECG pattern in a patient with coronary artery disease and combined amiodarone and betablocker therapy.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2008, Volume: 97, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Coronary Ar

2008
[Pain attacks causing muscle cramps].
    Duodecim; laaketieteellinen aikakauskirja, 1999, Volume: 115, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Disease; Defibrillators, Implantable; Elec

1999
[Experience with 5 years of drug therapy of ischemic heart disease patients with stable angina and stenosing atherosclerosis of the coronary arteries].
    Kardiologiia, 1987, Volume: 27, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Angina Pectoris; Calcium Channel Blockers; Cardiac G

1987