amiodarone has been researched along with Alzheimer Disease in 1 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In addition to Alzheimer's disease, compounds with dual properties may also be useful for drug development targeting other membrane proteins." | 1.36 | Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms. ( Ha, HR; Haass, C; Hamid, R; Herms, J; Hopson, J; Kamp, F; Lichtenthaler, SF; Mayer, TU; Mitterreiter, S; Nelson, DJ; Page, RM; Rossner, S; Stahl, T; Steiner, H; Winkler, E; Zeitschel, U, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitterreiter, S | 1 |
| Page, RM | 1 |
| Kamp, F | 1 |
| Hopson, J | 1 |
| Winkler, E | 1 |
| Ha, HR | 1 |
| Hamid, R | 1 |
| Herms, J | 1 |
| Mayer, TU | 1 |
| Nelson, DJ | 1 |
| Steiner, H | 1 |
| Stahl, T | 1 |
| Zeitschel, U | 1 |
| Rossner, S | 1 |
| Haass, C | 1 |
| Lichtenthaler, SF | 1 |
1 other study available for amiodarone and Alzheimer Disease
| Article | Year |
|---|---|
Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms.
Topics: Alzheimer Disease; Amiodarone; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precur | 2010 |