amiodarone has been researched along with Alveolitis, Fibrosing in 162 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to evaluate the pulmonary effects of amiodarone in patients with heart failure, in those with chronic obstructive pulmonary disease (COPD) and in those undergoing a surgical procedure." | 9.08 | Pulmonary effect of amiodarone in patients with heart failure. The Congestive Heart Failure-Survival Trial of Antiarrhythmic Therapy (CHF-STAT) Investigators (Veterans Affairs Cooperative Study No. 320). ( Deedwania, PC; Fisher, SG; Fletcher, RD; Rohatgi, P; Singh, BN; Singh, SN, 1997) |
| "Amiodarone (AMD), a medicine used to treat life-threatening arrhythmias, is frequently linked to pulmonary fibrosis (PF)." | 8.31 | Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin. ( Abdelhamid, WG; El Tabaa, MM; Elgharabawy, RM, 2023) |
| "Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and hepatotoxicity." | 8.02 | The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats. ( Ibrahim Fouad, G; R Mousa, M, 2021) |
| "In this case report, we present a successful case of en bloc heart-lung transplant in a patient with advanced cardiopulmonary respiratory failure from amiodarone-associated pulmonary fibrosis that occurred post-left ventricular assist device implantation." | 7.91 | Successful Heart-Lung Transplant for a Patient on Continuous-Flow Left Ventricular Assist Device Support Complicated With Amiodarone-Induced Pulmonary Fibrosis. ( Currie, ME; Mooney, J; Shudo, Y; Woo, YJ, 2019) |
| " We investigated the role of mast cells and macrophages on AM induced pulmonary fibrosis and the action of atorvastatin on this fibrosis." | 7.85 | The role of mast cells and macrophages in amiodarone induced pulmonary fibrosis and the possible attenuating role of atorvastatin. ( El-Mohandes, EM; Hassan, YF; Khalaf, HA; Moustafa, AM, 2017) |
| "The purpose of this study was to evaluate the effect of atorvastatin administration on amiodarone-induced pulmonary fibrosis in rats." | 7.83 | Coadministration of Atorvastatin and Amiodarone Increases the Risk of Pulmonary Fibrosis in Rats. ( Dabiri, S; Joukar, S; Kheradmand, H; Nasri, HR; Poursalehi, HR, 2016) |
| "Pulmonary opacities have many causes we are presenting a case of pulmonary opacity in a patient of breathlessness; who was on amiodarone for atrial fibrillation (AF)." | 7.80 | Amiodarone induced pulmonary toxicity in a case of atrial fibrillation. ( Deodhar, KY; Patil, AS; Ranpise, SM; Sirsikar, SS, 2014) |
| "The effects of neferine, a bisbenzylisoquinline alkaloid extracted from the Chinese traditional medicine seed embryo of Nelumbo nucifera Gaertn, on amiodarone-induced pulmonary fibrosis in mice were evaluated." | 7.79 | Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice. ( Liu, JD; Niu, CH; Wang, JL; Wang, Y; Xiao, JH, 2013) |
| "Amiodarone (AM) is an efficacious antidysrhythmic agent that can cause numerous adverse effects, including potentially life-threatening pulmonary fibrosis." | 7.72 | Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction. ( Brien, JF; Card, JW; Massey, TE; Racz, WJ, 2003) |
| "We report a case of pulmonary fibrosis in an infant receiving amiodarone for treatment of intractable atrioventricular reentrant tachycardia secondary to Wolff-Parkinson-White syndrome." | 7.70 | Amiodarone induced pulmonary fibrosis in infancy. ( Bowers, PN; Fields, J; Nehgme, R; Rosenfeld, LE; Schwartz, D, 1998) |
| "A 70-year-old woman suffering from atrial fibrillation was treated with amiodarone, but developed acute respiratory failure necessitating mechanical ventilation for four weeks." | 7.69 | [Respiratory insufficiency due to pulmonary toxicity of amiodarone]. ( Jukema, GJ; Kerkhof, SC; Strack van Schijndel, RJ; ter Maaten, JC, 1995) |
| "The most feared side-effect of long-term amiodarone therapy is progressive alveolitis/pneumonitis leading to pulmonary fibrosis." | 7.69 | [Amiodarone-induced pulmonary fibrosis]. ( Boros, I; Fazekas, T; Lengyel, C; Selmeczi, A; Várkonyi, T, 1996) |
| "Associated with amiodarone use is pneumonitis which may progress to life-threatening pulmonary fibrosis." | 7.67 | Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone. ( Brien, JF; Daniels, JM; Massey, TE, 1989) |
| " Amiodarone and desethylamiodarone concentration in serum (control group n = 33) and in erythrocyte haemolysate (control group n = 13) were determined in relapses of ventricular tachycardias (n = 7) and in pulmonary fibrosis as serious side effect (n = 3)." | 7.67 | [Control of anti-arrhythmia therapy with amiodarone. Value of the determination of blood levels]. ( Lüderitz, B; Nitsch, J, 1984) |
| "Amiodarone, a cardiac antiarrhythmic agent, has been associated with the development of interstitial pulmonary fibrosis in patients receiving prolonged therapy with the drug." | 7.67 | Amiodarone-induced pulmonary fibrosis in hamsters. ( Cantor, JO; Cerreta, JM; Mandl, I; Osman, M; Suarez, R; Turino, GM, 1984) |
| "A case of pulmonary fibrosis attributed to amiodarone was studied immunologically and morphologically." | 7.67 | Amiodarone-associated pulmonary fibrosis. Evidence of an immunologically mediated mechanism. ( Bell, R; Eudy, S; Fan, K; Fullenwider, J, 1987) |
| "Amiodarone-induced bilateral diffuse pulmonary fibrosis developed in a 47-year-old woman with idiopathic hypertrophic subvalvular aortic stenosis who had been treated with amiodarone (Cordarex), 300 mg daily for about 18 months." | 7.67 | [Steroid-refractory amiodarone-induced pulmonary fibrosis. Clinical features and morphology after an amiodarone-free interval of 3 months]. ( Esinger, W; Gröger, C; Hertrich, F; Köhler, G; Leinberger, H; Raute-Kreinsen, U; Schleiffer, T, 1988) |
| "Both synthesis and total content of lung elastin were measured after induction of interstitial pulmonary fibrosis in hamsters by a single intratracheal insufflation of amiodarone." | 7.67 | Increased synthesis of elastin in amiodarone-induced pulmonary fibrosis. ( Cantor, JO; Keller, S; Mandl, I; Turino, GM, 1987) |
| "Of 25 cases of idiopathic pulmonary fibrosis, confirmed by open chest lung biopsy between January 1979 and July 1981, 5 patients had been taking amiodarone in doses less than 600 mg daily for 1 to 6 years." | 7.66 | Amiodarone and pulmonary fibrosis. ( Bernadó, L; Laporte, JR; Morell, F; Morera, J; Ruiz, J; Vidal, R, 1983) |
| "Two cases of histologically proven pulmonary fibrosis resulting from amiodarone therapy but responding to corticosteroids are reported." | 7.66 | Pulmonary fibrosis--a serious side-effect of amiodarone therapy. ( Clarke, SW; Evans, TR; Ormerod, LP; Quyyumi, AA; Ward, RL, 1983) |
| "Amiodarone was used to treat cardiac arrhythmias that had been refractory to conventional medical therapy." | 7.66 | Toxic and therapeutic effects of amiodarone in the treatment of cardiac arrhythmias. ( Gorham, JP; Graham, EL; Greene, HL; Gross, BW; Kudenchuk, PJ; Sears, GK; Trobaugh, GB; Werner, JA, 1983) |
| "Six patients are presented who developed pulmonary infiltrates of undetermined origin while being treated for severe ventricular arrhythmias with amiodarone hydrochloride." | 7.66 | Pneumonitis and pulmonary fibrosis associated with amiodarone treatment: a possible complication of a new antiarrhythmic drug. ( Rakita, L; Sobol, SM, 1982) |
| "Pirfenidone is an antifibrotic agent potentially effective for IPF therapy, and preclinical and available clinical data support its use in IPF." | 6.43 | Pirfenidone for the treatment of idiopathic pulmonary fibrosis. ( Antoniu, SA, 2006) |
| "Amiodarone (AM) is an antidysrhythmic agent with a propensity to cause pulmonary toxicity, including potentially fatal fibrosis." | 5.31 | Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis. ( Bennett, BM; Brien, JF; Chung, WH; Massey, TE; Racz, WJ, 2001) |
| "The amiodarone-treated animals showed a significant reduction in the coefficient of diffusion (kCO) and a significant increase in lung hydroxyproline levels as compared to the control group." | 5.29 | Amiodarone-induced pulmonary fibrosis in Fischer 344 rats. ( Gairola, CG; Lai, YL; Reinhart, PG, 1996) |
| "To date, there have been three cases of pulmonary fibrosis in patients receiving mexiletine spontaneously reported to the manufacturer." | 5.28 | Possible association of pulmonary fibrosis with mexiletine. ( Bero, CJ; Rihn, TL, 1991) |
| "The purpose of this study was to evaluate the pulmonary effects of amiodarone in patients with heart failure, in those with chronic obstructive pulmonary disease (COPD) and in those undergoing a surgical procedure." | 5.08 | Pulmonary effect of amiodarone in patients with heart failure. The Congestive Heart Failure-Survival Trial of Antiarrhythmic Therapy (CHF-STAT) Investigators (Veterans Affairs Cooperative Study No. 320). ( Deedwania, PC; Fisher, SG; Fletcher, RD; Rohatgi, P; Singh, BN; Singh, SN, 1997) |
| "A case of amiodarone pulmonary toxicity (APT) is described following a low dosage of amiodarone (200 mg/day) with serious respiratory insufficiency in a patient after right pneumonectomy." | 4.78 | Low dose amiodarone pulmonary toxicity in a patient with a history of pneumonectomy. ( van der Zeyden, H; van Hengstum, M; Zandstra, D, 1992) |
| "Of the side effects that complicate amiodarone therapy, pulmonary fibrosis is potentially the most serious." | 4.76 | Amiodarone pulmonary toxicity. ( Mostow, N; Rakita, L; Sobol, SM; Vrobel, T, 1983) |
| "Amiodarone (AMD), a medicine used to treat life-threatening arrhythmias, is frequently linked to pulmonary fibrosis (PF)." | 4.31 | Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin. ( Abdelhamid, WG; El Tabaa, MM; Elgharabawy, RM, 2023) |
| "The therapeutic role of mesenchymal stem cells (MSCs) in cases of amiodarone (AD) induced pulmonary fibrosis (PF) has not been well studied." | 4.02 | Role of bone marrow-derived mesenchymal stem cells in alleviating pulmonary epithelium damage and extracellular matrix remodeling in a rat model of lung fibrosis induced by amiodarone. ( Abdel Halim, AS; Abdel Hamid, FF; Aglan, HA; Ahmed, HH; Mohamed, MR, 2021) |
| "Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and hepatotoxicity." | 4.02 | The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats. ( Ibrahim Fouad, G; R Mousa, M, 2021) |
| "Amiodarone is a high effectiveness anti-arrhythmia agent which is able to induce pulmonary fibrosis." | 3.96 | Amiodarone induces epithelial-mesenchymal transition in A549 cells via activation of TGF-β1. ( Chen, C; Chen, D; Chen, H; Tu, M; Wang, Z; Weng, J; Wu, H, 2020) |
| "In this case report, we present a successful case of en bloc heart-lung transplant in a patient with advanced cardiopulmonary respiratory failure from amiodarone-associated pulmonary fibrosis that occurred post-left ventricular assist device implantation." | 3.91 | Successful Heart-Lung Transplant for a Patient on Continuous-Flow Left Ventricular Assist Device Support Complicated With Amiodarone-Induced Pulmonary Fibrosis. ( Currie, ME; Mooney, J; Shudo, Y; Woo, YJ, 2019) |
| " We investigated the role of mast cells and macrophages on AM induced pulmonary fibrosis and the action of atorvastatin on this fibrosis." | 3.85 | The role of mast cells and macrophages in amiodarone induced pulmonary fibrosis and the possible attenuating role of atorvastatin. ( El-Mohandes, EM; Hassan, YF; Khalaf, HA; Moustafa, AM, 2017) |
| "The purpose of this study was to evaluate the effect of atorvastatin administration on amiodarone-induced pulmonary fibrosis in rats." | 3.83 | Coadministration of Atorvastatin and Amiodarone Increases the Risk of Pulmonary Fibrosis in Rats. ( Dabiri, S; Joukar, S; Kheradmand, H; Nasri, HR; Poursalehi, HR, 2016) |
| "Patients underwent amiodarone treatment for various reasons, most often atrial fibrillation, for more than 2 years, and those that received a cumulative dose > 100 g were enrolled." | 3.80 | The diagnostic utility of chest computed tomography scoring for the assessment of amiodarone-induced pulmonary toxicity. ( Kang, IS; Kim, KJ; Kim, Y; Park, SH, 2014) |
| "Pulmonary opacities have many causes we are presenting a case of pulmonary opacity in a patient of breathlessness; who was on amiodarone for atrial fibrillation (AF)." | 3.80 | Amiodarone induced pulmonary toxicity in a case of atrial fibrillation. ( Deodhar, KY; Patil, AS; Ranpise, SM; Sirsikar, SS, 2014) |
| "The effects of neferine, a bisbenzylisoquinline alkaloid extracted from the Chinese traditional medicine seed embryo of Nelumbo nucifera Gaertn, on amiodarone-induced pulmonary fibrosis in mice were evaluated." | 3.79 | Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice. ( Liu, JD; Niu, CH; Wang, JL; Wang, Y; Xiao, JH, 2013) |
| "Amiodarone (AM) is an efficacious antidysrhythmic agent that can cause numerous adverse effects, including potentially life-threatening pulmonary fibrosis." | 3.72 | Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction. ( Brien, JF; Card, JW; Massey, TE; Racz, WJ, 2003) |
| " Intratracheal AM administration resulted in pulmonary fibrosis 21 days posttreatment, as evidenced by an increased hydroxyproline content and histological damage." | 3.72 | Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity. ( Brien, JF; Card, JW; Margolin, SB; Massey, TE; Racz, WJ, 2003) |
| "This report deals with two cases of amiodarone induced pulmonary toxicity in dilated cardiomyopathy leading to respiratory insufficiency." | 3.71 | [Amiodarone induced pulmonary toxicity]. ( Alter, P; Grimm, W; Maisch, B, 2002) |
| "We report a case of pulmonary fibrosis in an infant receiving amiodarone for treatment of intractable atrioventricular reentrant tachycardia secondary to Wolff-Parkinson-White syndrome." | 3.70 | Amiodarone induced pulmonary fibrosis in infancy. ( Bowers, PN; Fields, J; Nehgme, R; Rosenfeld, LE; Schwartz, D, 1998) |
| "Associated with amiodarone (AM) therapy is pneumonitis, which may progress to life-threatening pulmonary fibrosis." | 3.69 | Investigation of the role of oxidative stress in amiodarone-induced pulmonary toxicity in the hamster. ( Brien, JF; Leeder, RG; Massey, TE, 1994) |
| "Amiodarone (AM) is an effective antidysrhythmic agent, the use of which is limited because of the drug's potential for causing life-threatening pulmonary fibrosis." | 3.69 | Comparison of the in vivo pulmonary toxicity of amiodarone and des-oxo-amiodarone in the hamster. ( Brien, JF; Chatla, N; Kabalka, GW; Leeder, RG; Massey, TE; Rafeiro, E, 1994) |
| "Intratracheal instillation of the antiarrhythmic drug amiodarone (AD) in hamsters is an established animal model of AD-induced pulmonary fibrosis." | 3.69 | Metabolism of amiodarone following intratracheal instillation in hamsters. ( Blake, TL; Reasor, MJ, 1995) |
| "The most feared side-effect of long-term amiodarone therapy is progressive alveolitis/pneumonitis leading to pulmonary fibrosis." | 3.69 | [Amiodarone-induced pulmonary fibrosis]. ( Boros, I; Fazekas, T; Lengyel, C; Selmeczi, A; Várkonyi, T, 1996) |
| "A 70-year-old woman suffering from atrial fibrillation was treated with amiodarone, but developed acute respiratory failure necessitating mechanical ventilation for four weeks." | 3.69 | [Respiratory insufficiency due to pulmonary toxicity of amiodarone]. ( Jukema, GJ; Kerkhof, SC; Strack van Schijndel, RJ; ter Maaten, JC, 1995) |
| "Amiodarone (AD) has been shown to produce a transient pulmonary fibrosis in hamsters after intratracheal (i." | 3.69 | Pulmonary responses to amiodarone in hamsters: comparison of intratracheal and oral administrations. ( Blake, TL; Reasor, MJ, 1995) |
| " Cells were obtained from patients with idiopathic pulmonary fibrosis (n = 10), patients with sarcoidosis (n = 20), and patients receiving amiodarone without evidence of clinical lung disease (n = 10) as well as from normal volunteers (n = 8)." | 3.68 | Alveolar macrophage surface carbohydrate expression is altered in interstitial lung disease as determined by lectin-binding profiles. ( Auerbach, R; Meyer, KC; Powers, C; Rosenthal, N, 1993) |
| "Amiodarone is a drug used to treat refractory tachyarrhythmias." | 3.68 | [Pneumopathy induced by amiodarone. Radiological data]. ( Balmaseda, C; Bordas, Y; Led, A; Mazas-Artasona, L, 1992) |
| " In five (idiopathic pulmonary fibrosis (IPF), allergic bronchopulmonary aspergillosis (ABPA), amiodarone-induced pneumonitis (AIP), chronic eosinophilic pneumonia (CEP), Churg-Strauss syndrome (CSS)) out of the thirteen groups we took into consideration, the level of eosinophils was greater than 4%." | 3.68 | Eosinophilic alveolitis in immunologic interstitial lung disorders. ( Bertorelli, G; Olivieri, D; Pesci, A, 1990) |
| "Two patients with coronary heart disease and previous myocardial infarction, treated with amiodarone for severe ventricular arrhythmias, developed pulmonary toxicity." | 3.68 | [Pulmonary toxicity due to amiodarone]. ( Ferrari, G; Galli, M; Politi, A, 1993) |
| " Amiodarone and desethylamiodarone concentration in serum (control group n = 33) and in erythrocyte haemolysate (control group n = 13) were determined in relapses of ventricular tachycardias (n = 7) and in pulmonary fibrosis as serious side effect (n = 3)." | 3.67 | [Control of anti-arrhythmia therapy with amiodarone. Value of the determination of blood levels]. ( Lüderitz, B; Nitsch, J, 1984) |
| "Both synthesis and total content of lung elastin were measured after induction of interstitial pulmonary fibrosis in hamsters by a single intratracheal insufflation of amiodarone." | 3.67 | Increased synthesis of elastin in amiodarone-induced pulmonary fibrosis. ( Cantor, JO; Keller, S; Mandl, I; Turino, GM, 1987) |
| "We describe a 59-year-old patient who was treated with amiodarone for severe ventricular arrhythmia." | 3.67 | [Lung changes in amiodarone therapy]. ( Frank, H; Hübsch, P; Prayer, L, 1989) |
| "A case of pneumonitis and pulmonary fibrosis occurring during long term treatment with amiodarone hydrochloride is described." | 3.67 | Lung disease associated with amiodarone treatment. ( Cosentino, G; De Vuono, T; Pesola, A; Vercillo, C, 1985) |
| "A covariate analysis was performed on the major lung function indices that are affected by pulmonary fibrosis in 29 patients who had recently started amiodarone therapy and compared with those of a group of 41 patients who had been treated for a mean of 19." | 3.67 | Amiodarone and chronic lung fibrosis. ( Faragher, EB; Finnegan, MJ, 1985) |
| "A case of pulmonary fibrosis attributed to amiodarone was studied immunologically and morphologically." | 3.67 | Amiodarone-associated pulmonary fibrosis. Evidence of an immunologically mediated mechanism. ( Bell, R; Eudy, S; Fan, K; Fullenwider, J, 1987) |
| "Amiodarone-induced bilateral diffuse pulmonary fibrosis developed in a 47-year-old woman with idiopathic hypertrophic subvalvular aortic stenosis who had been treated with amiodarone (Cordarex), 300 mg daily for about 18 months." | 3.67 | [Steroid-refractory amiodarone-induced pulmonary fibrosis. Clinical features and morphology after an amiodarone-free interval of 3 months]. ( Esinger, W; Gröger, C; Hertrich, F; Köhler, G; Leinberger, H; Raute-Kreinsen, U; Schleiffer, T, 1988) |
| "Amiodarone hydrochloride, an iodinated benzofuran derivative, is effective for treatment of supraventricular and ventricular arrhythmias." | 3.67 | Amiodarone toxicity: recurrence of interstitial pneumonitis after withdrawal of the drug. ( Morera, J; Navas, JJ; Ojanguren, I; Parra, O; Ruiz, J, 1989) |
| "Associated with amiodarone use is pneumonitis which may progress to life-threatening pulmonary fibrosis." | 3.67 | Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone. ( Brien, JF; Daniels, JM; Massey, TE, 1989) |
| "Amiodarone, a cardiac antiarrhythmic agent, has been associated with the development of interstitial pulmonary fibrosis in patients receiving prolonged therapy with the drug." | 3.67 | Amiodarone-induced pulmonary fibrosis in hamsters. ( Cantor, JO; Cerreta, JM; Mandl, I; Osman, M; Suarez, R; Turino, GM, 1984) |
| "Amiodarone was used to treat cardiac arrhythmias that had been refractory to conventional medical therapy." | 3.66 | Toxic and therapeutic effects of amiodarone in the treatment of cardiac arrhythmias. ( Gorham, JP; Graham, EL; Greene, HL; Gross, BW; Kudenchuk, PJ; Sears, GK; Trobaugh, GB; Werner, JA, 1983) |
| "Two cases of histologically proven pulmonary fibrosis resulting from amiodarone therapy but responding to corticosteroids are reported." | 3.66 | Pulmonary fibrosis--a serious side-effect of amiodarone therapy. ( Clarke, SW; Evans, TR; Ormerod, LP; Quyyumi, AA; Ward, RL, 1983) |
| "Of 25 cases of idiopathic pulmonary fibrosis, confirmed by open chest lung biopsy between January 1979 and July 1981, 5 patients had been taking amiodarone in doses less than 600 mg daily for 1 to 6 years." | 3.66 | Amiodarone and pulmonary fibrosis. ( Bernadó, L; Laporte, JR; Morell, F; Morera, J; Ruiz, J; Vidal, R, 1983) |
| "Amiodarone was administered to 80 patients with recurrent cardiac tachyarrhythmias previously resistant to drug treatment." | 3.66 | Adverse reactions during treatment with amiodarone hydrochloride. ( Garan, H; Kelly, E; McGovern, B; Ruskin, JN, 1983) |
| "Six patients are presented who developed pulmonary infiltrates of undetermined origin while being treated for severe ventricular arrhythmias with amiodarone hydrochloride." | 3.66 | Pneumonitis and pulmonary fibrosis associated with amiodarone treatment: a possible complication of a new antiarrhythmic drug. ( Rakita, L; Sobol, SM, 1982) |
| "We evaluated the effects of amiodarone in 45 patients with recurrent ventricular tachycardia or ventricular fibrillation." | 3.66 | Clinical efficacy and electrophysiology during long-term therapy for recurrent ventricular tachycardia or ventricular fibrillation. ( Heger, JJ; Jackman, WM; Naccarelli, GV; Prystowsky, EN; Rinkenberger, RL; Warfel, KA; Zipes, DP, 1981) |
| "Treatment of amiodarone pulmonary toxicity consists primarily of stopping amiodarone." | 2.46 | Amiodarone-induced pulmonary toxicity: an under-recognized and severe adverse effect? ( Berghaus, T; Haeckel, T; Schwaiblmair, M; von Scheidt, W; Wagner, T, 2010) |
| "Pirfenidone is an antifibrotic agent potentially effective for IPF therapy, and preclinical and available clinical data support its use in IPF." | 2.43 | Pirfenidone for the treatment of idiopathic pulmonary fibrosis. ( Antoniu, SA, 2006) |
| " The most serious adverse reaction is pulmonary toxicity." | 2.40 | [Amiodarone-induced pulmonary toxicity]. ( Berg, M; Heisel, A; Schieffer, H; Stopp, M; Ukena, D, 1997) |
| "Amiodarone, a drug that treats arrhythmias induces pulmonary toxicity through interplay between oxidative stress and inflammation." | 1.51 | Pulmonary Responses Following Quercetin Administration in Rats After Intratracheal Instillation of Amiodarone. ( Oka, VO; Okon, UE; Osim, EE, 2019) |
| "Amiodarone (AD) is a highly efficient antiarrhythmic drug with potentially serious side effects." | 1.40 | Altered surfactant homeostasis and alveolar epithelial cell stress in amiodarone-induced lung fibrosis. ( Chambers, RC; Guenther, A; Henneke, I; Knudsen, L; Korfei, M; Liebisch, G; Mahavadi, P; Ochs, M; Ruppert, C; Schmitz, G; Seeger, W; Vancheri, C; Venkatesan, S, 2014) |
| "Idiopathic pulmonary fibrosis (IPF), the most common and lethal of the idiopathic interstitial pneumonias, is defined by a radiological and/or pathological pattern of usual interstitial pneumonia (UIP)." | 1.40 | Differential diagnosis of usual interstitial pneumonia: when is it truly idiopathic? ( Bonella, F; Cavazza, A; Rossi, G; Spagnolo, P; Sverzellati, N; Wuyts, WA, 2014) |
| "Amiodarone was used because of paroxysmal atrial fibrillation in five patients and ventricular arrhythmia in one." | 1.33 | [The pulmonary toxicity of amiodarone: six-case report]. ( Ren, ZW, 2005) |
| "Amiodarone is a potent antiarrhythmic agent that is limited in clinical use by its adverse effects, including potentially life threatening amiodarone-induced pulmonary toxicity (AIPT)." | 1.32 | Value of technetium-99m diethyltriamine pentaaceticacid radioaerosol inhalation lung scintigraphy for the stage of amiodarone-induced pulmonary toxicity. ( Altaner, S; Altun, A; Berkada, S; Durmus-Altun, G; Ozbay, G; Sami Salihoglu, Y, 2004) |
| "Amiodarone is an amphiphilic, iodinated, benzofuran derivative that is known to be effective for refractory ventricular tachyarrhythmia." | 1.32 | [Analysis of increased hepatic density during chronic amiodarone therapy]. ( Abe, K; Ayabe, Y; Hirakawa, K; Nishimura, M, 2003) |
| " Male F344 rats were intratracheally dosed with AD (6." | 1.31 | Quantitative image analysis of drug-induced lung fibrosis using laser scanning confocal microscopy. ( Antonini, JM; Hubbs, AF; Reasor, MJ; Roberts, JR; Taylor, MD, 2002) |
| "Amiodarone (AM) is an antidysrhythmic agent with a propensity to cause pulmonary toxicity, including potentially fatal fibrosis." | 1.31 | Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis. ( Bennett, BM; Brien, JF; Chung, WH; Massey, TE; Racz, WJ, 2001) |
| "Amiodarone (AM) is a potent antidysrhythmic agent that is limited in clinical use by its adverse effects, including potentially life-threatening AM-induced pulmonary toxicity (AIPT)." | 1.30 | Effects of dietary vitamin E supplementation on pulmonary morphology and collagen deposition in amiodarone- and vehicle-treated hamsters. ( Bray, TM; Brien, JF; Card, JW; Leeder, RG; Massey, TE; Racz, WJ, 1999) |
| "Amiodarone is an effective antidysrhythmic agent, restricted in use by the development of pulmonary toxicity." | 1.29 | Resistance of the hamster to amiodarone-induced pulmonary toxicity following repeated intraperitoneal administration. ( Brien, JF; Evans, CD; Leeder, RG; Massey, TE, 1994) |
| "The amiodarone-treated animals showed a significant reduction in the coefficient of diffusion (kCO) and a significant increase in lung hydroxyproline levels as compared to the control group." | 1.29 | Amiodarone-induced pulmonary fibrosis in Fischer 344 rats. ( Gairola, CG; Lai, YL; Reinhart, PG, 1996) |
| "Noncardiovascular adverse effects associated with amiodarone result in substantial morbidity." | 1.29 | Risk factors for the development of specific noncardiovascular adverse effects associated with amiodarone. ( Follin, SL; Ordelova, A; Tisdale, JE; Webb, CR, 1995) |
| "Amiodarone can cause pulmonary toxicity along with an increase in phospholipid in macrophages, lymphocytes, and other cell types." | 1.29 | Amiodarone causes decreased cell-mediated immune responses and inhibits the phospholipase C signaling pathway. ( Clarkson, CE; Lippmann, ML; Wilson, BD, 1993) |
| "To date, there have been three cases of pulmonary fibrosis in patients receiving mexiletine spontaneously reported to the manufacturer." | 1.28 | Possible association of pulmonary fibrosis with mexiletine. ( Bero, CJ; Rihn, TL, 1991) |
| "Amiodarone treated rats exhibited pathologic evidence of amiodarone-induced lung disease after one week of treatment and this injury was sustained and more extensive during the remainder of the study period." | 1.28 | Natural killer cell activity in a rat model of amiodarone-induced interstitial lung disease. ( Karpel, JP; Mitsudo, S; Norin, AJ, 1991) |
| "Amiodarone, an antiarrhythmic drug with predominantly class III effects, has demonstrated serious adverse drug reactions and interactions." | 1.28 | Amiodarone: a postmarketing evaluation of monitoring for drug-induced toxicity. ( Fitzsimons, BM; Luck, JC; Meute, MA; Murphy, JA; Wiley, SW; Wilkinson, WC, 1990) |
| "Amiodarone was discontinued in all patients and corticosteroids were introduced in thirteen." | 1.28 | [Pneumonitis induced by amiodarone]. ( Cukier, A; Pileggi, F; Pinto, RM; Teixeira, LR; Terra Filho, M; Vargas, FS, 1989) |
| "We report a patient with fibrosing alveolitis associated with amiodarone therapy." | 1.27 | Fibrosing alveolitis associated with amiodarone. ( Butland, RJ; Millard, FJ, 1984) |
| " Initial symptomatic response followed high dosage corticosteroid and immunosuppressant treatment, but reduction in the dosage of corticosteroids was achieved only by successive plasma exchange with concomitant reduction in plasma concentrations of both amiodarone and immune complexes." | 1.27 | Amiodarone associated alveolitis and polyarthropathy. Treatment by plasma exchange. ( Douglas, AC; Paton, L; Russell, DC, 1983) |
| " The mean cumulative dosage of amiodarone was 229 g; clinical symptoms were mainly weight loss, asthenia, dyspnea and dry cough." | 1.27 | [Interstitial pneumopathies during amiodarone treatment. Determination of serum amiodarone, typing of lymphocytes from bronchiolo-alveolar lavage]. ( Boita, F; Bouquet, S; Debacque, I; Meurice, JC; Patte, F; Preud'Homme, JL; Underner, M, 1986) |
| "An unusual case of recurrence of amiodarone pulmonary toxicity is described." | 1.27 | [Recurrent alveolitis caused by amiodarone]. ( Ciani, F; Padrini, R; Pandullo, C; Pivotti, F; Scardi, S, 1986) |
| "Amiodarone is a cardiac antiarrhythmic agent now undergoing clinical trials in the United States." | 1.27 | Dense liver in a 72-year-old woman with congestive heart failure. ( Duncan-Myers, J; Jones, WP; Shin, MS; Stanley, RJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 77 (47.53) | 18.7374 |
| 1990's | 44 (27.16) | 18.2507 |
| 2000's | 19 (11.73) | 29.6817 |
| 2010's | 16 (9.88) | 24.3611 |
| 2020's | 6 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| El Tabaa, MM | 2 |
| Elgharabawy, RM | 1 |
| Abdelhamid, WG | 1 |
| Oka, VO | 1 |
| Okon, UE | 1 |
| Osim, EE | 1 |
| Radwan, SM | 1 |
| Ghoneim, D | 1 |
| Salem, M | 1 |
| Saeed, M | 1 |
| Saleh, Y | 1 |
| Elhamy, M | 1 |
| Wael, K | 1 |
| Shokair, O | 1 |
| Wahdan, SA | 1 |
| Abdel Halim, AS | 1 |
| Ahmed, HH | 1 |
| Aglan, HA | 1 |
| Abdel Hamid, FF | 1 |
| Mohamed, MR | 1 |
| Ibrahim Fouad, G | 1 |
| R Mousa, M | 1 |
| El-Mohandes, EM | 1 |
| Moustafa, AM | 1 |
| Khalaf, HA | 1 |
| Hassan, YF | 1 |
| Liu, X | 1 |
| Khadtare, N | 1 |
| Patel, H | 1 |
| Stephani, R | 1 |
| Cantor, J | 1 |
| Weng, J | 1 |
| Chen, H | 1 |
| Wu, H | 1 |
| Tu, M | 1 |
| Wang, Z | 2 |
| Chen, D | 1 |
| Chen, C | 1 |
| Currie, ME | 1 |
| Shudo, Y | 1 |
| Mooney, J | 1 |
| Woo, YJ | 1 |
| Oliveira, M | 1 |
| Melo, N | 1 |
| Mota, PC | 1 |
| E Bastos, HN | 1 |
| Pereira, JM | 1 |
| Carvalho, A | 1 |
| Guimarães, S | 1 |
| Moura, CS | 1 |
| Morais, A | 1 |
| Niu, CH | 1 |
| Wang, Y | 1 |
| Liu, JD | 1 |
| Wang, JL | 1 |
| Xiao, JH | 1 |
| Lakatos, G | 1 |
| Nádházi, Z | 1 |
| Igaz, P | 1 |
| Rácz, K | 1 |
| Mahavadi, P | 1 |
| Henneke, I | 1 |
| Ruppert, C | 1 |
| Knudsen, L | 1 |
| Venkatesan, S | 1 |
| Liebisch, G | 1 |
| Chambers, RC | 1 |
| Ochs, M | 1 |
| Schmitz, G | 1 |
| Vancheri, C | 1 |
| Seeger, W | 1 |
| Korfei, M | 1 |
| Guenther, A | 1 |
| Wuyts, WA | 1 |
| Cavazza, A | 1 |
| Rossi, G | 1 |
| Bonella, F | 1 |
| Sverzellati, N | 1 |
| Spagnolo, P | 1 |
| Sirsikar, SS | 1 |
| Ranpise, SM | 1 |
| Patil, AS | 1 |
| Deodhar, KY | 1 |
| Kang, IS | 1 |
| Kim, KJ | 1 |
| Kim, Y | 1 |
| Park, SH | 1 |
| Nasri, HR | 1 |
| Joukar, S | 1 |
| Kheradmand, H | 1 |
| Poursalehi, HR | 1 |
| Dabiri, S | 1 |
| Stiefelhagen, P | 1 |
| Heisel, A | 1 |
| Berg, M | 1 |
| Stopp, M | 1 |
| Ukena, D | 1 |
| Schieffer, H | 1 |
| Schwaiblmair, M | 1 |
| Berghaus, T | 1 |
| Haeckel, T | 1 |
| Wagner, T | 1 |
| von Scheidt, W | 1 |
| Hsieh, YC | 1 |
| Huang, JL | 1 |
| Chin, CS | 1 |
| Lin, TC | 1 |
| Liao, YC | 1 |
| Ting, CT | 1 |
| Wu, TJ | 1 |
| Schreiber, J | 1 |
| Jackevicius, CA | 1 |
| Tom, A | 1 |
| Essebag, V | 1 |
| Eisenberg, MJ | 1 |
| Rahme, E | 1 |
| Tu, JV | 1 |
| Humphries, K | 1 |
| Behlouli, H | 1 |
| Pilote, L | 1 |
| Briassoulis, G | 1 |
| Stefanaki, K | 1 |
| Peristeri, I | 1 |
| Endoh, Y | 1 |
| Hatzis, T | 1 |
| Card, JW | 3 |
| Racz, WJ | 4 |
| Brien, JF | 8 |
| Massey, TE | 8 |
| Uhal, BD | 1 |
| Wang, R | 1 |
| Laukka, J | 1 |
| Zhuang, J | 1 |
| Soledad-Conrad, V | 1 |
| Filippatos, G | 1 |
| Hirakawa, K | 1 |
| Abe, K | 1 |
| Ayabe, Y | 1 |
| Nishimura, M | 1 |
| Margolin, SB | 1 |
| Punithavathi, D | 1 |
| Venkatesan, N | 1 |
| Babu, M | 1 |
| Durmus-Altun, G | 1 |
| Altun, A | 1 |
| Sami Salihoglu, Y | 1 |
| Altaner, S | 1 |
| Berkada, S | 1 |
| Ozbay, G | 1 |
| Ren, ZW | 1 |
| Antoniu, SA | 1 |
| Pannier, R | 1 |
| Hesselmann, J | 1 |
| Huep, WW | 1 |
| Schröder, E | 1 |
| Acar, J | 1 |
| Pernes, JM | 1 |
| Grimberg, D | 1 |
| Jaillon, P | 1 |
| Dezile, G | 1 |
| Roullier, A | 1 |
| Arbeille-Brassart, B | 1 |
| Lubbe, WF | 1 |
| Mercer, CJ | 1 |
| Waxman, HL | 1 |
| Groh, WC | 1 |
| Marchlinski, FE | 1 |
| Buxton, AE | 1 |
| Sadowski, LM | 1 |
| Horowitz, LN | 1 |
| Josephson, ME | 1 |
| Kastor, JA | 1 |
| Harris, L | 1 |
| McKenna, WJ | 1 |
| Rowland, E | 1 |
| Holt, DW | 1 |
| Storey, GC | 1 |
| Krikler, DM | 1 |
| Rakita, L | 2 |
| Sobol, SM | 2 |
| Mostow, N | 1 |
| Vrobel, T | 1 |
| Ruesch, C | 1 |
| Chabry, E | 1 |
| Joux, A | 1 |
| Bayon, M | 1 |
| Emonot, A | 1 |
| McGovern, B | 1 |
| Garan, H | 1 |
| Kelly, E | 1 |
| Ruskin, JN | 1 |
| Nitsch, J | 1 |
| Lüderitz, B | 1 |
| Vergnon, JM | 1 |
| Wiesendanger, T | 1 |
| Bellemin, JP | 1 |
| Brune, J | 1 |
| Arlet, P | 1 |
| Carré, P | 1 |
| Bismuth, JM | 1 |
| Larregain-Fournier, D | 1 |
| Le Tallec, Y | 1 |
| Fournier, JP | 1 |
| Palmier, B | 1 |
| Marsan, P | 1 |
| Dorne, R | 1 |
| Garrigue, G | 1 |
| Moura, A | 1 |
| Choma, L | 1 |
| Bendhack, LI | 1 |
| Koslin, DB | 1 |
| Chapman, P | 1 |
| Youker, JE | 1 |
| Troup, P | 1 |
| Manresa, F | 1 |
| Garau, J | 1 |
| Gausí, C | 1 |
| Juanmiquel Isern, L | 1 |
| Vidal Pla, R | 1 |
| de Gracia Roldán, X | 1 |
| Morera Prat, J | 2 |
| Butland, RJ | 1 |
| Millard, FJ | 1 |
| Pozzi, E | 1 |
| Sada, E | 1 |
| Luisetti, M | 1 |
| De Rose, V | 1 |
| Scelsi, M | 1 |
| van Rooij, WJ | 1 |
| van der Meer, SC | 2 |
| van Royen, EA | 2 |
| van Zandwijk, N | 2 |
| Darmanata, JI | 1 |
| Akoun, GM | 2 |
| Gauthier-Rahman, S | 1 |
| Milleron, BJ | 2 |
| Perrot, JY | 1 |
| Mayaud, CM | 2 |
| Quyyumi, AA | 1 |
| Ormerod, LP | 1 |
| Clarke, SW | 1 |
| Evans, TR | 1 |
| Ward, RL | 1 |
| Russell, DC | 1 |
| Paton, L | 1 |
| Douglas, AC | 1 |
| Schrijver, G | 1 |
| Allison, SN | 1 |
| Meinders, AE | 1 |
| Chaillet, JL | 1 |
| Dantas, JC | 1 |
| Pinheiro Neto, J | 1 |
| Sampaio, WP | 1 |
| Greene, HL | 1 |
| Graham, EL | 1 |
| Werner, JA | 1 |
| Sears, GK | 1 |
| Gross, BW | 1 |
| Gorham, JP | 1 |
| Kudenchuk, PJ | 1 |
| Trobaugh, GB | 1 |
| van Rooy, WJ | 1 |
| Darmanata, JL | 1 |
| Cantor, JO | 2 |
| Osman, M | 1 |
| Cerreta, JM | 1 |
| Suarez, R | 1 |
| Mandl, I | 2 |
| Turino, GM | 2 |
| Heger, JJ | 1 |
| Prystowsky, EN | 1 |
| Jackman, WM | 1 |
| Naccarelli, GV | 1 |
| Warfel, KA | 1 |
| Rinkenberger, RL | 1 |
| Zipes, DP | 1 |
| Morera, J | 3 |
| Vidal, R | 2 |
| Morell, F | 2 |
| Ruiz, J | 3 |
| Bernadó, LL | 1 |
| Laporte, JR | 2 |
| Zaher, C | 1 |
| Hamer, A | 1 |
| Peter, T | 1 |
| Mandel, W | 1 |
| Bernadó, L | 1 |
| Antolin, J | 1 |
| Cabrera, P | 1 |
| Amerigo, MJ | 1 |
| Gordo, P | 1 |
| Pitton, MB | 1 |
| Schweden, F | 1 |
| Lenci, G | 1 |
| ter Maaten, JC | 1 |
| Strack van Schijndel, RJ | 1 |
| Jukema, GJ | 1 |
| Kerkhof, SC | 1 |
| Tisdale, JE | 1 |
| Follin, SL | 1 |
| Ordelova, A | 1 |
| Webb, CR | 1 |
| Blake, TL | 2 |
| Reasor, MJ | 5 |
| Agnant, RA | 1 |
| Louis, R | 1 |
| Bury, T | 1 |
| Radermecker, MF | 1 |
| Leeder, RG | 4 |
| Rafeiro, E | 1 |
| Kabalka, GW | 1 |
| Chatla, N | 1 |
| Evans, CD | 1 |
| Voshaar, T | 1 |
| Chai, JL | 1 |
| Patz, EF | 1 |
| Meyer, KC | 1 |
| Powers, C | 1 |
| Rosenthal, N | 1 |
| Auerbach, R | 1 |
| Politi, A | 1 |
| Galli, M | 1 |
| Ferrari, G | 1 |
| Wilson, BD | 2 |
| Clarkson, CE | 2 |
| Lippmann, ML | 2 |
| Reinhart, PG | 1 |
| Lai, YL | 1 |
| Gairola, CG | 1 |
| Hargreaves, MR | 1 |
| Benson, MK | 1 |
| Lengyel, C | 1 |
| Boros, I | 1 |
| Várkonyi, T | 1 |
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| Fazekas, T | 1 |
| Leipner, N | 1 |
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| Liesenfeld, H | 1 |
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| Károlyi, A | 1 |
| Singh, SN | 1 |
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| Deedwania, PC | 1 |
| Rohatgi, P | 1 |
| Singh, BN | 1 |
| Fletcher, RD | 1 |
| Drent, M | 1 |
| Cobben, NA | 1 |
| Van Dieijen-Visser, MP | 1 |
| Braat, SH | 1 |
| Wouters, EF | 1 |
| Bowers, PN | 1 |
| Fields, J | 1 |
| Schwartz, D | 1 |
| Rosenfeld, LE | 1 |
| Nehgme, R | 1 |
| Bray, TM | 1 |
| Carrión Valero, F | 1 |
| Marín Pardo, J | 1 |
| Taylor, MD | 2 |
| Van Dyke, K | 1 |
| Bowman, LL | 1 |
| Miles, PR | 1 |
| Hubbs, AF | 2 |
| Mason, RJ | 1 |
| Shannon, K | 1 |
| Iliopoulou, A | 1 |
| Pagou, H | 1 |
| Giannakopoulos, G | 1 |
| Spiropoulos, T | 1 |
| Vernhet, H | 1 |
| Bousquet, C | 1 |
| Durand, G | 1 |
| Giron, J | 1 |
| Senac, JP | 1 |
| Chung, WH | 1 |
| Bennett, BM | 1 |
| Hiranniramol, S | 1 |
| Braman, S | 1 |
| O'Brien, A | 1 |
| Alter, P | 1 |
| Grimm, W | 1 |
| Maisch, B | 1 |
| Kharabsheh, S | 1 |
| Abendroth, CS | 1 |
| Kozak, M | 1 |
| Roberts, JR | 1 |
| Antonini, JM | 1 |
| Mazas-Artasona, L | 1 |
| Led, A | 1 |
| Balmaseda, C | 1 |
| Bordas, Y | 1 |
| Giri, SN | 2 |
| Wang, Q | 2 |
| Coudert, B | 1 |
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| Lombard, JN | 1 |
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| Dettenmeier, PA | 1 |
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| Luck, JC | 1 |
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| Fraioli, P | 1 |
| Barberis, M | 1 |
| Montemurro, L | 1 |
| White, JP | 1 |
| Ward, MJ | 1 |
| Tatti, V | 1 |
| Ramelli, G | 1 |
| Brett, W | 1 |
| Cooper, JA | 1 |
| Zitnik, RJ | 1 |
| Matthay, RA | 1 |
| Terra Filho, M | 2 |
| Vargas, FS | 2 |
| Cukier, A | 2 |
| Teixeira, LR | 1 |
| Pinto, RM | 1 |
| Pileggi, F | 1 |
| Foresti, V | 1 |
| Pepe, R | 1 |
| Parisio, E | 1 |
| De Filippi, G | 1 |
| Scolari, N | 1 |
| Frigerio, C | 1 |
| Prayer, L | 1 |
| Hübsch, P | 1 |
| Frank, H | 1 |
| Sevillano Martín, C | 1 |
| Callol Sánchez, L | 1 |
| Calderón Alvarez, J | 1 |
| Moreno Muro, M | 1 |
| Gómez de Terreros, FJ | 1 |
| Friedrich, M | 1 |
| Hoffmann, E | 1 |
| Mitlehner, W | 1 |
| Daniels, JM | 1 |
| Parra, O | 1 |
| Ojanguren, I | 1 |
| Navas, JJ | 1 |
| Keller, S | 1 |
| Esinger, W | 1 |
| Schleiffer, T | 1 |
| Leinberger, H | 1 |
| Hertrich, F | 1 |
| Köhler, G | 1 |
| Gröger, C | 1 |
| Raute-Kreinsen, U | 1 |
| De Carvalho, CR | 1 |
| Saldiva, PH | 1 |
| Barbas, CS | 1 |
| Kairalla, RA | 1 |
| Barbas Filho, JV | 1 |
| Romeiro Neto, MM | 1 |
| Lecklitner, ML | 1 |
| Johnson, DR | 1 |
| Hughes, JJ | 1 |
| Fan, K | 1 |
| Bell, R | 1 |
| Eudy, S | 1 |
| Fullenwider, J | 1 |
| Defrance, P | 1 |
| Van Cang, G | 1 |
| Laurent, K | 1 |
| Labenne, P | 1 |
| De Jonghe, M | 1 |
| Xaubet, A | 1 |
| Roca, J | 1 |
| Rodriguez-Roisin, R | 1 |
| Herranz, J | 1 |
| Marin, A | 1 |
| Lomeña, F | 1 |
| Montserrat, JM | 1 |
| Agustí-Vidal, A | 1 |
| Paredes, R | 2 |
| Ruiz Manzano, J | 1 |
| Michel, FB | 1 |
| Godard, P | 1 |
| Aubas, P | 1 |
| Vic, P | 1 |
| Meurice, JC | 1 |
| Debacque, I | 1 |
| Boita, F | 1 |
| Underner, M | 1 |
| Bouquet, S | 1 |
| Preud'Homme, JL | 1 |
| Patte, F | 1 |
| Myers, JL | 1 |
| Kennedy, JI | 1 |
| Plumb, VJ | 1 |
| Huet, C | 1 |
| Ortoli, JM | 1 |
| Gerber, F | 1 |
| Abelanet, R | 1 |
| Hirsch, A | 1 |
| López, AM | 1 |
| Sánchez, C | 1 |
| Palazzo, JP | 1 |
| Visconti, RJ | 1 |
| Lunardi, W | 1 |
| Lopes, EA | 1 |
| Kehde, E | 1 |
| Pereira Júnior, W | 1 |
| Uip, DE | 1 |
| Hernández, EA | 1 |
| Duarte, MI | 1 |
| Bensaid, J | 1 |
| Guéret, P | 1 |
| Blanc, P | 1 |
| Doumeix, JJ | 1 |
| Virot, P | 1 |
| Pinaud, D | 1 |
| Bontemps, T | 1 |
| Vergnoux, H | 1 |
| Leymarie, JL | 1 |
| Melloni, B | 1 |
| Bolognesi, R | 1 |
| Vasini, P | 1 |
| Manca, C | 1 |
| Cimicchi, MC | 1 |
| Pezzarossa, A | 1 |
| Scardi, S | 1 |
| Ciani, F | 1 |
| Pandullo, C | 1 |
| Padrini, R | 1 |
| Pivotti, F | 1 |
| Adams, PC | 1 |
| Gibson, GJ | 1 |
| Morley, AR | 1 |
| Wright, AJ | 1 |
| Corris, PA | 1 |
| Reid, DS | 1 |
| Campbell, RW | 1 |
| Moreau, X | 1 |
| Quilichini, R | 1 |
| Aubert, L | 1 |
| Chagnon, A | 1 |
| Ducoloné, A | 1 |
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| Braggio, P | 1 |
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| Ganassini, A | 1 |
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| Vercillo, C | 1 |
| De Vuono, T | 1 |
| Jones, WP | 1 |
| Shin, MS | 1 |
| Stanley, RJ | 1 |
| Duncan-Myers, J | 1 |
| Atienza, A | 1 |
| Micó, L | 1 |
| Bonora, V | 1 |
| Caballero, M | 1 |
| Llanos, R | 1 |
| Pacheco, S | 1 |
| Escobar, L | 1 |
15 reviews available for amiodarone and Alveolitis, Fibrosing
| Article | Year |
|---|---|
[Amiodarone-induced pulmonary toxicity].
Topics: Amiodarone; Anti-Arrhythmia Agents; Bronchial Spasm; Controlled Clinical Trials as Topic; Cryptogeni | 1997 |
Amiodarone-induced pulmonary toxicity: an under-recognized and severe adverse effect?
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug-Related Side Effects and Adverse Reac | 2010 |
[Drug-induced lung diseases].
Topics: Amiodarone; Anti-Arrhythmia Agents; Antineoplastic Agents; Bronchial Diseases; Diagnosis, Differenti | 2011 |
Pirfenidone for the treatment of idiopathic pulmonary fibrosis.
Topics: Administration, Oral; Amiodarone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Cell | 2006 |
Amiodarone pulmonary toxicity.
Topics: Adrenal Cortex Hormones; Adult; Aged; Amiodarone; Benzofurans; Dose-Response Relationship, Drug; Fem | 1983 |
[Diffuse interstitial pneumonitis. Possible responsibility of amiodarone. Apropos of a case and review of the literature].
Topics: Adrenal Cortex Hormones; Aged; Amiodarone; Benzofurans; Female; Humans; Pulmonary Fibrosis; Radiogra | 1983 |
[Pulmonary toxicity caused by drugs].
Topics: Acute Disease; Amiodarone; Anti-Arrhythmia Agents; Anti-Infective Agents, Urinary; Anti-Inflammatory | 1999 |
Amiodarone pneumonitis. Bronchoalveolar lavage findings in 15 patients and review of the literature.
Topics: Aged; Aged, 80 and over; Amiodarone; Bronchoalveolar Lavage Fluid; Cell Count; Humans; Male; Middle | 1992 |
Low dose amiodarone pulmonary toxicity in a patient with a history of pneumonectomy.
Topics: Aged; Amiodarone; Angina Pectoris; Humans; Male; Pneumonectomy; Pulmonary Fibrosis; Respiration, Art | 1992 |
The histopathology of pulmonary reactions to drugs.
Topics: Amiodarone; Antirheumatic Agents; Biopsy; Bleomycin; Cyclophosphamide; Diagnosis, Differential; Eosi | 1990 |
Amiodarone pulmonary toxicity: morphologic and biochemical features.
Topics: Amiodarone; Animals; Cricetinae; Humans; Lung; Pulmonary Fibrosis; Rats | 1991 |
Drug-induced adverse pulmonary reactions.
Topics: Amiodarone; Asthma; Bleomycin; Carmustine; Drug-Related Side Effects and Adverse Reactions; Gold; Hu | 1985 |
Mechanisms of drug-induced pulmonary disease.
Topics: Alveolitis, Extrinsic Allergic; Amiodarone; Bleomycin; Bronchial Spasm; Humans; Lung Diseases; Pulmo | 1988 |
[Amiodarone-induced segmental lung infiltration. Radiologic and computed tomographic aspects].
Topics: Amiodarone; Humans; Male; Middle Aged; Pulmonary Fibrosis; Radionuclide Imaging; Tomography, X-Ray C | 1989 |
[Pulmonary toxicity caused by amiodarone].
Topics: Amiodarone; Benzofurans; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Lung Disea | 1986 |
1 trial available for amiodarone and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Pulmonary effect of amiodarone in patients with heart failure. The Congestive Heart Failure-Survival Trial of Antiarrhythmic Therapy (CHF-STAT) Investigators (Veterans Affairs Cooperative Study No. 320).
Topics: Aged; Amiodarone; Carbon Monoxide; Heart Failure; Humans; Lung; Lung Diseases, Obstructive; Prospect | 1997 |
146 other studies available for amiodarone and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin.
Topics: Amiodarone; Animals; Fibrosis; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphatidylinositol 3 | 2023 |
Pulmonary Responses Following Quercetin Administration in Rats After Intratracheal Instillation of Amiodarone.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antioxidants; Bronchoalveolar Lavage Fluid; Female; Inj | 2019 |
Adipose Tissue-Derived Mesenchymal Stem Cells Protect Against Amiodarone-Induced Lung Injury in Rats.
Topics: Actins; Adipose Tissue; Amiodarone; Animals; Cell Proliferation; Fibroblast Growth Factor 7; Flow Cy | 2020 |
Role of bone marrow-derived mesenchymal stem cells in alleviating pulmonary epithelium damage and extracellular matrix remodeling in a rat model of lung fibrosis induced by amiodarone.
Topics: Amiodarone; Animals; Bone Marrow; Bone Marrow Cells; Epithelium; Extracellular Matrix; Mesenchymal S | 2021 |
The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats.
Topics: Alanine Transaminase; Amiodarone; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cyt | 2021 |
The role of mast cells and macrophages in amiodarone induced pulmonary fibrosis and the possible attenuating role of atorvastatin.
Topics: Amiodarone; Animals; Atorvastatin; Immunohistochemistry; Macrophages; Male; Mast Cells; Pulmonary Fi | 2017 |
Transient Blockade of Endothelin-1 Mitigates Amiodarone-Induced Pulmonary Fibrosis.
Topics: Amiodarone; Animals; Apoptosis; Becaplermin; Bronchoalveolar Lavage Fluid; Chemokine CXCL12; Collage | 2018 |
Amiodarone induces epithelial-mesenchymal transition in A549 cells via activation of TGF-β1.
Topics: A549 Cells; Actins; Amiodarone; Anti-Arrhythmia Agents; Cadherins; Epithelial-Mesenchymal Transition | 2020 |
Successful Heart-Lung Transplant for a Patient on Continuous-Flow Left Ventricular Assist Device Support Complicated With Amiodarone-Induced Pulmonary Fibrosis.
Topics: Amiodarone; Anti-Arrhythmia Agents; Heart Failure; Heart-Assist Devices; Heart-Lung Transplantation; | 2019 |
Pleuroparenchymal Fibroelastosis as Another Potential Lung Toxicity Pattern Induced by Amiodarone.
Topics: Amiodarone; Humans; Lung; Pulmonary Fibrosis | 2020 |
Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice.
Topics: Amiodarone; Animals; Benzylisoquinolines; Body Weight; Cell Count; Hydroxyproline; Interleukin-2 Rec | 2013 |
[The "blue man"].
Topics: Amiodarone; Anti-Arrhythmia Agents; Eye; Humans; Hyperthyroidism; Hypothyroidism; Lung; Male; Middle | 2013 |
Altered surfactant homeostasis and alveolar epithelial cell stress in amiodarone-induced lung fibrosis.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Apoptosis; Cathepsin D; Cell Culture Techniques; Cell L | 2014 |
Differential diagnosis of usual interstitial pneumonia: when is it truly idiopathic?
Topics: Alveolitis, Extrinsic Allergic; Amiodarone; Arthritis, Rheumatoid; Diagnosis, Differential; Humans; | 2014 |
Amiodarone induced pulmonary toxicity in a case of atrial fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Male; Middle Aged; Pulmonary Fibros | 2014 |
The diagnostic utility of chest computed tomography scoring for the assessment of amiodarone-induced pulmonary toxicity.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cross-Sectional Studies; Cryptogenic | 2014 |
Coadministration of Atorvastatin and Amiodarone Increases the Risk of Pulmonary Fibrosis in Rats.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Lung; Male; Pulmonary Alveoli; | 2016 |
Drug-induced interstitial pneumonia.
Topics: Amiodarone; Cytotoxins; Drug-Related Side Effects and Adverse Reactions; Humans; Imidazolidines; Lun | 2008 |
[A hypertensive patient with atrial fibrillation has increasing dyspnea. Cardiac or pulmonary etiology?].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dyspnea; Electric Countershock; Femal | 2009 |
Pre-clinical detection of amiodarone-induced acute fibrosing alveolitis by intra-thoracic impedance monitor of an implantable cardioverter-defibrillator.
Topics: Acute Disease; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; Defibrillators, Implantab | 2011 |
Population-level incidence and risk factors for pulmonary toxicity associated with amiodarone.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Comorbidity; Femal | 2011 |
Occasionally, I have atrial fibrillation. I hate it, but I hate taking medications, too. My doctor wants me to go on amiodarone. Can you tell me if it has any side effects? I need to decide which is worse--the problem or the medication?
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Lung Injury; Pneumonia; Pulmonary F | 2010 |
Is KL-6 a serum indicator of early pulmonary fibrosis in childhood cancer patients?
Topics: Amiodarone; Anti-Arrhythmia Agents; Antigens; Antigens, Neoplasm; Biomarkers; Biopsy; Bone Marrow Tr | 2003 |
Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antioxidants; Cricetinae; Diet; DNA Probes; Gene Expres | 2003 |
Inhibition of amiodarone-induced lung fibrosis but not alveolitis by angiotensin system antagonists.
Topics: Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Ant | 2003 |
[Analysis of increased hepatic density during chronic amiodarone therapy].
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Liver; Male; Mid | 2003 |
Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity.
Topics: Acute Disease; Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2003 |
Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats.
Topics: Amiodarone; Animals; Bronchoalveolar Lavage Fluid; Collagen Type I; Curcumin; Dose-Response Relation | 2003 |
Value of technetium-99m diethyltriamine pentaaceticacid radioaerosol inhalation lung scintigraphy for the stage of amiodarone-induced pulmonary toxicity.
Topics: Aerosols; Amiodarone; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Diagnosis, Differential | 2004 |
[The pulmonary toxicity of amiodarone: six-case report].
Topics: Aged; Amiodarone; Female; Humans; Male; Middle Aged; Prognosis; Pulmonary Fibrosis; Radiography | 2005 |
Drug induced lung disease.
Topics: Alveolitis, Extrinsic Allergic; Amiodarone; Antineoplastic Agents; Asthma; Drug Hypersensitivity; Hu | 1983 |
[Life threatening alveolitis and hemolysis following amiodarone].
Topics: Amiodarone; Anemia, Hemolytic; Benzofurans; Cardiac Complexes, Premature; Heart Failure; Humans; Mal | 1983 |
[Pulmonary fibrosis during a treatment with amiodarone. A possible side-effect].
Topics: Amiodarone; Benzofurans; Female; Humans; Middle Aged; Pulmonary Fibrosis | 1983 |
[Interstitial pneumopathy in subjects treated with amiodarone].
Topics: Adult; Aged; Amiodarone; Benzofurans; Humans; Hyperplasia; Lung; Male; Pulmonary Fibrosis | 1983 |
Amiodarone: its side effects, adverse reactions and dosage schedules.
Topics: Amiodarone; Benzofurans; Central Nervous System Diseases; Drug Administration Schedule; Eye Diseases | 1982 |
Amiodarone for control of sustained ventricular tachyarrhythmia: clinical and electrophysiologic effects in 51 patients.
Topics: Adolescent; Adult; Aged; Amiodarone; Benzofurans; Cardiac Pacing, Artificial; Chemical and Drug Indu | 1982 |
Side effects of long-term amiodarone therapy.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Corneal Diseases; Dose-Response Relation | 1983 |
Adverse reactions during treatment with amiodarone hydrochloride.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Digoxin; Drug Interactions; Female; Huma | 1983 |
[Control of anti-arrhythmia therapy with amiodarone. Value of the determination of blood levels].
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Erythrocytes; Humans; Long-Term Care; Mi | 1984 |
[Amiodarone: a new etiology of diffuse interstitial pneumopathy? Apropos of 2 personal cases and 10 cases from the literature].
Topics: Aged; Amiodarone; Benzofurans; Female; Humans; Lung; Male; Middle Aged; Pulmonary Fibrosis | 1984 |
[Amiodarone: a new cause of hypersensitivity pneumopathy?].
Topics: Aged; Amiodarone; Benzofurans; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Pneumonia; | 1984 |
[Pulmonary fibrosis during treatment involving amiodarone].
Topics: Aged; Amiodarone; Benzofurans; Humans; Male; Pulmonary Fibrosis; Tachycardia | 1984 |
[Amiodarone and diffuse alveolar-interstitial pulmonary infiltrate. A case report].
Topics: Amiodarone; Benzofurans; Dexamethasone; Female; Humans; Lung; Middle Aged; Oxygen Inhalation Therapy | 1984 |
Amiodarone-induced pulmonary toxicity.
Topics: Aged; Amiodarone; Autopsy; Benzofurans; Biopsy; Follow-Up Studies; Glucocorticoids; Humans; Lung; Ma | 1984 |
[Interstitial pneumonitis and amiodarone].
Topics: Aged; Amiodarone; Benzofurans; Coronary Disease; Humans; Male; Middle Aged; Prednisone; Pulmonary Fi | 1984 |
[Pulmonary disease caused by amiodarone].
Topics: Aged; Amiodarone; Benzofurans; Humans; Male; Pulmonary Fibrosis | 1984 |
Fibrosing alveolitis associated with amiodarone.
Topics: Aged; Amiodarone; Benzofurans; Humans; Male; Pulmonary Fibrosis; Tachycardia; Time Factors | 1984 |
Interstitial pneumopathy and low-dosage amiodarone.
Topics: Amiodarone; Atrial Fibrillation; Benzofurans; Biopsy; Humans; Lung; Male; Middle Aged; Pulmonary Fib | 1984 |
Pulmonary gallium-67 uptake in amiodarone pneumonitis.
Topics: Aged; Amiodarone; Benzofurans; Gallium Radioisotopes; Humans; Lung; Male; Middle Aged; Pulmonary Fib | 1984 |
Amiodarone-induced hypersensitivity pneumonitis. Evidence of an immunological cell-mediated mechanism.
Topics: Aged; Alveolitis, Extrinsic Allergic; Amiodarone; Benzofurans; Cell Migration Inhibition; Drug Hyper | 1984 |
Pulmonary fibrosis--a serious side-effect of amiodarone therapy.
Topics: Adult; Amiodarone; Benzofurans; Biopsy; Humans; Lung; Male; Middle Aged; Prednisolone; Pulmonary Fib | 1983 |
Amiodarone associated alveolitis and polyarthropathy. Treatment by plasma exchange.
Topics: Amiodarone; Benzofurans; Female; Humans; Joint Diseases; Middle Aged; Plasma Exchange; Pneumonia; Pr | 1983 |
[Interstitial and alveolar lung changes following treatment with amiodarone].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Benzofurans; Female; Humans; Myocardial Infarction; Pulmon | 1983 |
[Interstitial pneumonia associated with the use of amiodarone. Report of a case].
Topics: Aged; Amiodarone; Benzofurans; Humans; Male; Pulmonary Fibrosis; Radiography | 1983 |
Toxic and therapeutic effects of amiodarone in the treatment of cardiac arrhythmias.
Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Corneal Diseases; Digitalis Glycosides; Drug Interact | 1983 |
[Lung abnormalities in interstitium and alveoli following treatment with amiodarone].
Topics: Amiodarone; Benzofurans; Gallium Radioisotopes; Humans; Pulmonary Fibrosis; Radionuclide Imaging | 1984 |
Amiodarone-induced pulmonary fibrosis in hamsters.
Topics: Amiodarone; Animals; Benzofurans; Cricetinae; Hemorrhage; Inflammation; Lung; Lung Diseases; Mesocri | 1984 |
Clinical efficacy and electrophysiology during long-term therapy for recurrent ventricular tachycardia or ventricular fibrillation.
Topics: Adult; Aged; Amiodarone; Benzofurans; Drug Evaluation; Electric Stimulation; Electrophysiology; Fema | 1981 |
Pulmonary fibrosis and amiodarone.
Topics: Aged; Amiodarone; Benzofurans; Humans; Middle Aged; Pulmonary Fibrosis | 1982 |
Low-dose steroid therapy for prophylaxis of amiodarone-induced pulmonary infiltrates.
Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Humans; Male; Middle Aged; Pneumonia; Prednisone; Pul | 1983 |
Amiodarone and pulmonary fibrosis.
Topics: Aged; Amiodarone; Benzofurans; Female; Humans; Male; Middle Aged; Pulmonary Fibrosis | 1983 |
Amiodarone and the lung.
Topics: Amiodarone; Benzofurans; Humans; Pulmonary Fibrosis | 1983 |
Pneumonitis and pulmonary fibrosis associated with amiodarone treatment: a possible complication of a new antiarrhythmic drug.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Coronary Disease; Female; Heart Failure; | 1982 |
[Computerized tomography aspects of amiodarone poisoning].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Coronary Disease; Dose-Response Relationship, Drug; Female | 1995 |
[Respiratory insufficiency due to pulmonary toxicity of amiodarone].
Topics: Aged; Amiodarone; Atrial Fibrillation; Dyspnea; Female; Humans; Pulmonary Fibrosis; Respiratory Insu | 1995 |
Risk factors for the development of specific noncardiovascular adverse effects associated with amiodarone.
Topics: Adult; Age Factors; Aged; Amiodarone; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; | 1995 |
Pulmonary responses to amiodarone in hamsters: comparison of intratracheal and oral administrations.
Topics: Administration, Oral; Amiodarone; Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Hydroxyproline; | 1995 |
[Clinical case of the month. Apropos of a case of amiodarone-induced lung disease].
Topics: Amiodarone; Humans; Male; Middle Aged; Pulmonary Fibrosis; Tomography, X-Ray Computed; Wolff-Parkins | 1995 |
Investigation of the role of oxidative stress in amiodarone-induced pulmonary toxicity in the hamster.
Topics: Acetylcysteine; Allyl Compounds; Amiodarone; Animals; Antioxidants; Butylated Hydroxyanisole; Cricet | 1994 |
Comparison of the in vivo pulmonary toxicity of amiodarone and des-oxo-amiodarone in the hamster.
Topics: Amiodarone; Animals; Cricetinae; Hydroxyproline; Lung; Male; Mesocricetus; Organ Size; Pulmonary Fib | 1994 |
Resistance of the hamster to amiodarone-induced pulmonary toxicity following repeated intraperitoneal administration.
Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Cricetinae; Disease Models, Animal; Hydro | 1994 |
[Comments on the contribution by B.-D. Gonska (drug therapy). Amiodarone].
Topics: Amiodarone; Bronchial Hyperreactivity; Humans; Lung Diseases, Obstructive; Pulmonary Fibrosis; Risk | 1994 |
CT of the lung: patterns of calcification and other high-attenuation abnormalities.
Topics: Amiodarone; Calcinosis; Contrast Media; Humans; Lung Diseases; Lung Neoplasms; Pulmonary Fibrosis; T | 1994 |
Alveolar macrophage surface carbohydrate expression is altered in interstitial lung disease as determined by lectin-binding profiles.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Binding, Competitive; Bronchoalveolar Lavage | 1993 |
[Pulmonary toxicity due to amiodarone].
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Humans; Lung; Male; Middle Aged; Myocardial Infarction; Myoc | 1993 |
Amiodarone causes decreased cell-mediated immune responses and inhibits the phospholipase C signaling pathway.
Topics: Amiodarone; Animals; Dose-Response Relationship, Drug; Hypersensitivity, Delayed; Immune Tolerance; | 1993 |
Metabolism of amiodarone following intratracheal instillation in hamsters.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cricetinae; Disease Models, Animal; Intubation, Intratr | 1995 |
Amiodarone-induced pulmonary fibrosis in Fischer 344 rats.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Carbon Monoxide; Diffusion; Disease Models, Animal; Fem | 1996 |
Amiodarone pneumonitis: no safe dose.
Topics: Aged; Amiodarone; Humans; Male; Pulmonary Fibrosis; Vasodilator Agents | 1996 |
[Amiodarone-induced pulmonary fibrosis].
Topics: Amiodarone; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Pulmonary Fibrosis; Radio | 1996 |
[Early pulmonary changes caused by amiodarone].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Coronary Disease; Dose-Response Relationship, Drug; Drug A | 1996 |
[Amiodarone-induced pulmonary fibrosis].
Topics: Amiodarone; Glucocorticoids; Humans; Male; Methylprednisolone Hemisuccinate; Middle Aged; Pulmonary | 1997 |
Serum lactate dehydrogenase activity: indicator of the development of pneumonitis induced by amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Biomarkers; Female; Humans; L-Lactate | 1998 |
Amiodarone induced pulmonary fibrosis in infancy.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Electrocardiography, Ambulatory; Fo | 1998 |
Effects of dietary vitamin E supplementation on pulmonary morphology and collagen deposition in amiodarone- and vehicle-treated hamsters.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Collagen; Cricetinae; Dietary Supplements; Hydroxyproli | 1999 |
A characterization of amiodarone-induced pulmonary toxicity in F344 rats and identification of surfactant protein-D as a potential biomarker for the development of the toxicity.
Topics: Albumins; Amiodarone; Animals; Anti-Arrhythmia Agents; Biomarkers; Bronchoalveolar Lavage Fluid; Cel | 2000 |
Amiodarone-induced pulmonary interstitial fibrosis.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Humans; Male; Pulmonary Fibrosis | 2000 |
Reversible amiodarone-induced lung disease: HRCT findings.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Male; Middle Aged; Pulmonary Fibrosis; Rad | 2001 |
Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis.
Topics: Amiodarone; Animals; Gene Expression Regulation; Humans; Hydroxyproline; Immunohistochemistry; Lung; | 2001 |
Cracking a dyspnea mystery. Drug-induced pulmonary fibrosis.
Topics: Aged; Amiodarone; Dyspnea; Humans; Male; Pulmonary Fibrosis | 2001 |
[Amiodarone induced pulmonary toxicity].
Topics: Adult; Aged; Amiodarone; Cardiomyopathy, Dilated; Humans; Long-Term Care; Male; Pneumonia; Pulmonary | 2002 |
Fatal pulmonary toxicity occurring within two weeks of initiation of amiodarone.
Topics: Acute Disease; Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Administration Schedule; Fatal Outcome | 2002 |
Quantitative image analysis of drug-induced lung fibrosis using laser scanning confocal microscopy.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Bleomycin; Disease Models, | 2002 |
[Pneumopathy induced by amiodarone. Radiological data].
Topics: Adrenal Cortex Hormones; Aged; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Male; Middle Aged; | 1992 |
Taurine and niacin offer a novel therapeutic modality in prevention of chemically-induced pulmonary fibrosis in hamsters.
Topics: Amiodarone; Animals; Bleomycin; Cricetinae; Drug Therapy, Combination; Niacin; Pulmonary Fibrosis; T | 1992 |
Bronchoalveolar lavage cell count and differential are not reliable indicators of amiodarone-induced pneumonitis.
Topics: Aged; Amiodarone; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count; Humans; Middle Aged; Predi | 1992 |
[Pulmonary toxicity of amiodarone].
Topics: Aged; Aged, 80 and over; Amiodarone; Female; Humans; Pulmonary Fibrosis | 1992 |
[Pneumonitis from amiodarone].
Topics: Aged; Amiodarone; Humans; Male; Pulmonary Fibrosis | 1992 |
Ga-67 imaging of amiodarone pulmonary toxicity with pseudocavitary lung lesion.
Topics: Aged; Amiodarone; Gallium Radioisotopes; Humans; Lung; Male; Pulmonary Fibrosis; Radionuclide Imagin | 1992 |
Attenuation of amiodarone-induced lung fibrosis and phospholipidosis in hamsters by taurine and/or niacin treatment.
Topics: Administration, Oral; Amiodarone; Animals; Collagen; Cricetinae; Drug Combinations; Hydroxyproline; | 1992 |
Bronchoalveolar lavage cell data in amiodarone-associated pneumonitis. Evaluation in 22 patients.
Topics: Aged; Amiodarone; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; Cell Count; Female; Huma | 1991 |
Pharmacologic and other chemical causes of interstitial lung disease.
Topics: Amiodarone; Bleomycin; Humans; Nitrofurantoin; Pulmonary Fibrosis | 1991 |
Possible association of pulmonary fibrosis with mexiletine.
Topics: Aged; Amiodarone; Humans; Male; Mexiletine; Pulmonary Fibrosis; Tachycardia; Tomography, X-Ray Compu | 1991 |
Natural killer cell activity in a rat model of amiodarone-induced interstitial lung disease.
Topics: Amiodarone; Animals; Killer Cells, Natural; Lung; Lymphocyte Activation; Male; Pulmonary Fibrosis; R | 1991 |
Amiodarone-induced pulmonary inflammation. Correlation with drug dose and lung levels of drug, metabolite, and phospholipid.
Topics: Amiodarone; Animals; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Dose-Respon | 1991 |
Eosinophilic alveolitis in immunologic interstitial lung disorders.
Topics: Adult; Aged; Amiodarone; Aspergillosis, Allergic Bronchopulmonary; Bronchoalveolar Lavage Fluid; Chu | 1990 |
Amiodarone: a postmarketing evaluation of monitoring for drug-induced toxicity.
Topics: Amiodarone; Drug Interactions; Humans; Monitoring, Physiologic; Product Surveillance, Postmarketing; | 1990 |
Spontaneous regression of amiodarone pulmonary toxicity.
Topics: Aged; Amiodarone; Female; Humans; Lung; Male; Middle Aged; Pulmonary Fibrosis; Radiography; Remissio | 1990 |
[Interstitial pneumopathy and amiodarone].
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Cardiac Complexes, Premature; Humans; Male; Pul | 1986 |
Drug induced lung disease.
Topics: Amiodarone; Bleomycin; Bronchial Spasm; Contraceptives, Oral; Female; Humans; Hypertension, Pulmonar | 1986 |
[Pneumonitis induced by amiodarone].
Topics: Aged; Aged, 80 and over; Amiodarone; Cardiac Complexes, Premature; Female; Humans; Male; Middle Aged | 1989 |
Angiotensin-converting enzyme as a possible marker for lung toxicity in amiodarone-treated patients.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Biomarkers; Female; Humans; Lung | 1989 |
[Lung changes in amiodarone therapy].
Topics: Amiodarone; Arrhythmias, Cardiac; Humans; Male; Middle Aged; Pulmonary Fibrosis | 1989 |
[Pulmonary toxicity of amiodarone].
Topics: Aged; Amiodarone; Bronchoalveolar Lavage Fluid; Humans; Male; Microscopy, Electron; Pulmonary Fibros | 1989 |
Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone.
Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Cricetinae; Disease Models, Animal; Histo | 1989 |
Amiodarone toxicity: recurrence of interstitial pneumonitis after withdrawal of the drug.
Topics: Amiodarone; Arrhythmias, Cardiac; Humans; Male; Methylprednisolone; Middle Aged; Pulmonary Fibrosis; | 1989 |
Increased synthesis of elastin in amiodarone-induced pulmonary fibrosis.
Topics: Amiodarone; Animals; Cricetinae; Elastin; Female; Lung; Lysine; Mesocricetus; Pulmonary Fibrosis | 1987 |
[Steroid-refractory amiodarone-induced pulmonary fibrosis. Clinical features and morphology after an amiodarone-free interval of 3 months].
Topics: Adipose Tissue; Amiodarone; Cortisone; Drug Resistance; Female; Humans; Liver; Lung; Middle Aged; Pu | 1988 |
[Pneumonitis due to amiodarone: fibrosis and/or phospholipidosis. Report of 2 cases].
Topics: Amiodarone; Female; Gallium Radioisotopes; Humans; Lung; Middle Aged; Phospholipids; Pulmonary Fibro | 1988 |
Gallium-67 and pulmonary complications of amiodarone.
Topics: Aged; Amiodarone; Diagnosis, Differential; Gallium Radioisotopes; Heart Failure; Humans; Male; Pulmo | 1988 |
Amiodarone-associated pulmonary fibrosis. Evidence of an immunologically mediated mechanism.
Topics: Amiodarone; Coronary Disease; Drug Therapy, Combination; Electrophoresis, Polyacrylamide Gel; Fluore | 1987 |
[Pulmonary toxicity of amiodarone].
Topics: Amiodarone; Humans; Lung; Male; Middle Aged; Pulmonary Diffusing Capacity; Pulmonary Fibrosis; Radio | 1987 |
Bronchoalveolar lavage cellular analysis and gallium lung scan in the assessment of patients with amiodarone-induced pneumonitis.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Bronchoalveolar Lavage Fluid; Coronary Disease; Follo | 1987 |
[Pulmonary damage by drugs].
Topics: Amiodarone; Amphotericin B; Humans; Lung; Pleural Effusion; Pulmonary Edema; Pulmonary Fibrosis | 1987 |
[Lung, mirror of iatrogenic diseases. Example of amiodarone].
Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Humans; Lipidoses; Lung Diseases; Male; Middle Aged; P | 1986 |
[Interstitial pneumopathies during amiodarone treatment. Determination of serum amiodarone, typing of lymphocytes from bronchiolo-alveolar lavage].
Topics: Aged; Amiodarone; Bronchi; Female; Humans; Lymphocytes; Male; Pulmonary Alveoli; Pulmonary Fibrosis; | 1986 |
Amiodarone lung: pathologic findings in clinically toxic patients.
Topics: Aged; Amiodarone; Female; Humans; Lung; Macrophages; Male; Microscopy, Electron; Middle Aged; Pulmon | 1987 |
[Intralysosomal granules in bronchial cells and ingestion of amiodarone. Apropos of a case of interstitial pneumonia].
Topics: Aged; Amiodarone; Bronchi; Female; Humans; Pulmonary Fibrosis | 1986 |
[Pulmonary toxicity associated with the use of amiodarone].
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Lung; Male; Middle Aged; Pulmonary Fibrosis; | 1986 |
[Pneumonitis and pulmonary fibrosis due to amiodarone. Report of 2 cases with optic and electronic microscopy].
Topics: Aged; Amiodarone; Humans; Lung; Male; Middle Aged; Pulmonary Fibrosis | 1986 |
[Pneumopathy caused by amiodarone. An often unrecognized iatrogenic entity].
Topics: Aged; Amiodarone; Humans; Male; Middle Aged; Pulmonary Fibrosis | 1987 |
[Pneumonitis caused by amiodarone. Description of a case and review of the literature].
Topics: Aged; Aged, 80 and over; Amiodarone; Female; Humans; Pulmonary Fibrosis; Radiography; Radionuclide I | 1987 |
Amiodarone.
Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Drug Interactions; Heart Diseases; Heart Ventricles; | 1986 |
[Recurrent alveolitis caused by amiodarone].
Topics: Amiodarone; Benzofurans; Eye Diseases; Female; Humans; Hyperthyroidism; Hypothyroidism; Middle Aged; | 1986 |
Amiodarone pulmonary toxicity: clinical and subclinical features.
Topics: Adult; Aged; Amiodarone; Female; Forced Expiratory Volume; Humans; Lung; Lung Diseases; Male; Middle | 1986 |
[Nephrotic syndrome and multivisceral manifestations in a patient treated with amiodarone].
Topics: Amiodarone; Arthritis; Humans; Male; Middle Aged; Nephrotic Syndrome; Pulmonary Fibrosis | 1986 |
[Interstitial pneumopathy caused by amiodarone].
Topics: Amiodarone; Benzofurans; Humans; Male; Middle Aged; Pulmonary Fibrosis | 1985 |
Amiodarone-induced pulmonary toxicity.
Topics: Amiodarone; Benzofurans; Cough; Dyspnea; Female; Humans; Middle Aged; Pulmonary Fibrosis; Respirator | 1986 |
[Spectrometric and ultrastructural study of pneumopathy induced by amiodarone].
Topics: Aged; Amiodarone; Benzofurans; Humans; Lung; Male; Pulmonary Fibrosis; Spectrometry, X-Ray Emission | 1985 |
Amiodarone and chronic lung fibrosis.
Topics: Amiodarone; Benzofurans; Blood Gas Analysis; Female; Forced Expiratory Volume; Humans; Lung Volume M | 1985 |
[Amiodarone pulmonary toxicity].
Topics: Amiodarone; Benzofurans; Humans; Lung Diseases; Pneumonia; Pulmonary Fibrosis | 1985 |
[Pneumopathies caused by hypersensitivity to amiodarone and associated nephropathies. Study by alveolar lavage].
Topics: Acute Kidney Injury; Aged; Amiodarone; Benzofurans; Drug Hypersensitivity; Female; Humans; Kidney Di | 1985 |
Lung disease associated with amiodarone treatment.
Topics: Aged; Amiodarone; Benzofurans; Coronary Disease; Female; Humans; Pneumonia; Pulmonary Fibrosis; Radi | 1985 |
Dense liver in a 72-year-old woman with congestive heart failure.
Topics: Aged; Amiodarone; Benzofurans; Chemical and Drug Induced Liver Injury; Female; Heart Failure; Humans | 1985 |
[Fibrosing pulmonary alveolitis induced by amiodarone].
Topics: Aged; Amiodarone; Benzofurans; Humans; Male; Pulmonary Fibrosis | 1985 |
[Pulmonary fibrosis induced by amiodarone].
Topics: Amiodarone; Benzofurans; Female; Humans; Lung; Middle Aged; Pulmonary Fibrosis; Radiography; Respira | 1985 |