Page last updated: 2024-10-22

amiodarone and Agranulocytosis

amiodarone has been researched along with Agranulocytosis in 5 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
" The objectives of this study were to evaluate the risk of ATD-related agranulocytosis in patients with amiodarone-induced thyrotoxicosis (AIT), and to compare it with the agranulocytosis risk in patients with thyrotoxicosis due to other etiologies treated with ATDs."7.91Increased Risk of Antithyroid Drug Agranulocytosis Associated with Amiodarone-Induced Thyrotoxicosis: A Population-Based Cohort Study. ( Gershinsky, M; Gronich, N; Lavi, I; Saliba, W; Shapira, C, 2019)
" The objectives of this study were to evaluate the risk of ATD-related agranulocytosis in patients with amiodarone-induced thyrotoxicosis (AIT), and to compare it with the agranulocytosis risk in patients with thyrotoxicosis due to other etiologies treated with ATDs."3.91Increased Risk of Antithyroid Drug Agranulocytosis Associated with Amiodarone-Induced Thyrotoxicosis: A Population-Based Cohort Study. ( Gershinsky, M; Gronich, N; Lavi, I; Saliba, W; Shapira, C, 2019)
"Thyrotoxicosis is a common disorder, especially in women."2.48Thyrotoxicosis. ( Boelaert, K; Franklyn, JA, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gershinsky, M1
Saliba, W1
Lavi, I1
Shapira, C1
Gronich, N1
Jamieson, A1
Seymour, M1
Morton, A1
Franklyn, JA1
Boelaert, K1
Camarero, V1
Llata, L1
Ruiz, E1
Torres, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Open-label, Parallel-group Study to Explore the Efficacy of High-intensity Focused Ultrasound (HIFU) Versus Fixed-dose Radioiodine-131 in the Treatment of Relapsed Graves' Disease[NCT03013257]240 participants (Actual)Interventional2017-04-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for amiodarone and Agranulocytosis

ArticleYear
Thyrotoxicosis.
    Lancet (London, England), 2012, Mar-24, Volume: 379, Issue:9821

    Topics: Agranulocytosis; Amiodarone; Antithyroid Agents; Atrial Fibrillation; Autoimmune Diseases; Child; Ex

2012

Other Studies

4 other studies available for amiodarone and Agranulocytosis

ArticleYear
Increased Risk of Antithyroid Drug Agranulocytosis Associated with Amiodarone-Induced Thyrotoxicosis: A Population-Based Cohort Study.
    Thyroid : official journal of the American Thyroid Association, 2019, Volume: 29, Issue:2

    Topics: Adult; Aged; Agranulocytosis; Amiodarone; Antithyroid Agents; Female; Humans; Male; Methimazole; Mid

2019
Drugs, the Thyroid, and the Heart: A Lethal Cocktail.
    The American journal of medicine, 2019, Volume: 132, Issue:3

    Topics: Agranulocytosis; Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Atrial Fibrillation; Carbim

2019
Unilateral facial swelling in a thyrotoxic patient.
    BMJ (Clinical research ed.), 2017, Feb-09, Volume: 356

    Topics: Aged; Agranulocytosis; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Edema; Face; Fev

2017
[Plasmapheresis in amiodarone-induced hyperthyroidism].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2006, Volume: 26, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Agranulocytosis; Amiodarone; Anti-Arrhythmia Agents; Antithyroid

2006