amiodarone has been researched along with Acute Liver Injury, Drug-Induced in 155 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and hepatotoxicity." | 8.02 | The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats. ( Ibrahim Fouad, G; R Mousa, M, 2021) |
| "Amiodarone is a di-iodated benzofuran derivative that is commonly used to treat patients with various cardiac arrhythmias." | 7.79 | [A case of simultaneously occurred amiodarone-induced hepatitis and hypothyroidism]. ( Chae, HB; Cho, YS; Han, JH; Kang, KM; Kim, JS; Lim, JC; Park, SM, 2013) |
| "The aim of this work was to analyze the prevalence of level function disorder in patients with atrial fibrillation taking constantly amiodarone." | 7.77 | [Abnormal liver function during therapy with amiodarone in patients with persistent atrial fibrillation]. ( Buniatian, ND; Korsun, LV; Sviridenko, AV; Uteshev, DB; Voronkina, MV, 2011) |
| "to study the association between the presence of the metabolic syndrome or right-sided heart failure and the prevalence of amiodarone induced liver disease." | 7.75 | Amiodarone hepatotoxicity in the context of the metabolic syndrome and right-sided heart failure. ( Gradus-Pizlo, I; Juliar, B; Kwo, PY; Mattar, W, 2009) |
| "Amiodarone may still be safely prescribed for Chinese patients who have baseline liver dysfunction." | 7.73 | Prevalence of amiodarone-related hepatotoxicity in 720 Chinese patients with or without baseline liver dysfunction. ( Chan, WW; Fung, JW; Ho, SS; Hui, HH; Kum, LC; Sanderson, JE; Wong, GW; Yu, CM, 2006) |
| "An objective causal assessment suggests that rhabdomyolysis, renal failure, and possibly hepatotoxicity were probably related to an amiodarone-simvastatin interaction." | 7.73 | Simvastatin-amiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity. ( Guirguis, A; Ricaurte, B; Taylor, HC; Zabriskie, D, 2006) |
| "We describe a case of hepatotoxicity, pancreatitis and inappropriate ADH secretion syndrome developed in a patient receiving chronic amiodarone treatment, not related to other causes." | 7.69 | [Pancreatitis and inappropriate ADH secretion syndrome associated with amiodarone]. ( Calvo Elipe, A; Gilsanz Fernández, C; Gorgojo Martínez, JJ; Guerrero Vega, E; Muñoz Ruiz, AI; Vera López, E, 1996) |
| "We report, for the first time to our knowledge, heart failure and liver abnormalities which developed after 2 months of treatment with tocainide." | 7.67 | Heart failure and hepatitis in a patient taking tocainide. ( Hertzberger, DH; Nauta, IL; Rensing, JB; Ruland, CM, 1984) |
| "We report a case of amiodarone-induced hepatitis accompanied by hyperthyroidism in which estimations of amiodarone in blood and in the liver and histological examinations were performed at the start and end of a 3-month interval." | 7.67 | A case of amiodarone-induced hyperthyroidism and hepatitis: results of clinical laboratory and histological tests. ( Gay, G; Netter, P; Roche, JP; Tréchot, P; Zannad, F, 1986) |
| "Amiodarone is an antiarrhythmic drug that has been recognized to induce hepatotoxicity." | 5.62 | Fatal acute-on-chronic liver failure in amiodarone-related steatohepatitis: a case report. ( Ho, CM; Tsai, JH; Wu, IU, 2021) |
| "Hepatotoxicity due to intravenous amiodarone (HIVAD) is a rare side effect with a distinct pattern of enzyme disturbances compared to liver damage from oral amiodarone." | 5.37 | Acute amiodarone liver toxicity likely due to ischemic hepatitis. ( Fried, M; Gluck, N; Porat, R, 2011) |
| " Amiodarone can effectively prevent and control postoperative atrial and ventricular fibrillation." | 4.82 | Hepatotoxicity during rapid intravenous loading with amiodarone: Description of three cases and review of the literature. ( Drewe, J; Krähenbühl, S; Pargger, H; Rätz Bravo, AE; Schlienger, RG; Ummenhofer, W, 2005) |
| "Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and hepatotoxicity." | 4.02 | The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats. ( Ibrahim Fouad, G; R Mousa, M, 2021) |
| "Dronedarone, a non-iodinated derivative of amiodarone, has been approved for use as a second-line agent for atrial fibrillation (AF)." | 3.79 | The dronedarone shared-care clinical model and database: a coordinated paradigm to optimize management of evolving clinical recommendations. ( Cinnamond, N; Connolly, M; Damani, L; Hussey, S; Menown, IB, 2013) |
| "Amiodarone is a di-iodated benzofuran derivative that is commonly used to treat patients with various cardiac arrhythmias." | 3.79 | [A case of simultaneously occurred amiodarone-induced hepatitis and hypothyroidism]. ( Chae, HB; Cho, YS; Han, JH; Kang, KM; Kim, JS; Lim, JC; Park, SM, 2013) |
| "The aim of this work was to analyze the prevalence of level function disorder in patients with atrial fibrillation taking constantly amiodarone." | 3.77 | [Abnormal liver function during therapy with amiodarone in patients with persistent atrial fibrillation]. ( Buniatian, ND; Korsun, LV; Sviridenko, AV; Uteshev, DB; Voronkina, MV, 2011) |
| "Amiodarone is commonly used in the treatment of refractory paroxysmal atrial fibrillation." | 3.76 | Hepatic dysfunction and neurotoxicity in a patient receiving long-term low-dose amiodarone therapy. ( Arkun, A; Birkhahn, RH; Grau, T; Van Deusen, SK, 2010) |
| "to study the association between the presence of the metabolic syndrome or right-sided heart failure and the prevalence of amiodarone induced liver disease." | 3.75 | Amiodarone hepatotoxicity in the context of the metabolic syndrome and right-sided heart failure. ( Gradus-Pizlo, I; Juliar, B; Kwo, PY; Mattar, W, 2009) |
| "Amiodarone may still be safely prescribed for Chinese patients who have baseline liver dysfunction." | 3.73 | Prevalence of amiodarone-related hepatotoxicity in 720 Chinese patients with or without baseline liver dysfunction. ( Chan, WW; Fung, JW; Ho, SS; Hui, HH; Kum, LC; Sanderson, JE; Wong, GW; Yu, CM, 2006) |
| "An objective causal assessment suggests that rhabdomyolysis, renal failure, and possibly hepatotoxicity were probably related to an amiodarone-simvastatin interaction." | 3.73 | Simvastatin-amiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity. ( Guirguis, A; Ricaurte, B; Taylor, HC; Zabriskie, D, 2006) |
| "We describe a case of hepatotoxicity, pancreatitis and inappropriate ADH secretion syndrome developed in a patient receiving chronic amiodarone treatment, not related to other causes." | 3.69 | [Pancreatitis and inappropriate ADH secretion syndrome associated with amiodarone]. ( Calvo Elipe, A; Gilsanz Fernández, C; Gorgojo Martínez, JJ; Guerrero Vega, E; Muñoz Ruiz, AI; Vera López, E, 1996) |
| "We report a case of amiodarone-induced hepatitis accompanied by hyperthyroidism in which estimations of amiodarone in blood and in the liver and histological examinations were performed at the start and end of a 3-month interval." | 3.67 | A case of amiodarone-induced hyperthyroidism and hepatitis: results of clinical laboratory and histological tests. ( Gay, G; Netter, P; Roche, JP; Tréchot, P; Zannad, F, 1986) |
| "We report, for the first time to our knowledge, heart failure and liver abnormalities which developed after 2 months of treatment with tocainide." | 3.67 | Heart failure and hepatitis in a patient taking tocainide. ( Hertzberger, DH; Nauta, IL; Rensing, JB; Ruland, CM, 1984) |
| "Drug-induced steatohepatitis is a rare form of liver injury known to be caused by only a handful of compounds." | 2.52 | Mechanistic review of drug-induced steatohepatitis. ( Guo, GL; Schumacher, JD, 2015) |
| " Despite the widespread use of amiodarone, prospective clinical studies have been sparse and there has been little consensus among experts in the field regarding optimum monitoring for adverse effects in patients receiving this drug." | 2.44 | Amiodarone hepatotoxicity. ( Babatin, M; Lee, SS; Pollak, PT, 2008) |
| "Amiodarone is an effective antiarrhythmic agent for preventing and treating atrial and ventricular arrhythmias." | 2.44 | Fatal amiodarone-induced hepatotoxicity: a case report and literature review. ( Chan, AL; Hsieh, HJ; Hsieh, YA; Lin, SJ, 2008) |
| "Amiodarone has been reported to cause asymptomatic increases in liver function tests in 15-55% of patients." | 2.38 | Hepatotoxicity associated with amiodarone therapy. ( Chase, SL; Flaharty, KK; Rubin, R; Yaghsezian, HM, 1989) |
| "Amiodarone is an antiarrhythmic drug that has been recognized to induce hepatotoxicity." | 1.62 | Fatal acute-on-chronic liver failure in amiodarone-related steatohepatitis: a case report. ( Ho, CM; Tsai, JH; Wu, IU, 2021) |
| "Amiodarone is a widely used antiarrhythmic drug that can cause the development of steatohepatitis as well as liver fibrosis and cirrhosis." | 1.56 | Autophagy alleviates amiodarone-induced hepatotoxicity. ( Bantel, H; Frangež, Ž; John, K; Liebig, S; Pfeffer, TJ; Schulze-Osthoff, K; Shibolet, O; Simon, HU; Veltmann, C; Vondran, F; Wandrer, F; Wedemeyer, H, 2020) |
| "Amiodarone is a highly effective treatment for supraventricular and ventricular tachyarrhythmia; however, it could be associated with several serious adverse effects, including liver injury." | 1.48 | Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports. ( Hayashi, K; Kawashiri, MA; Kurose, N; Nishida, N; Oyama, T; Sakata, K; Sasaki, M; Sawada, T; Tada, H; Tanaka, Y; Tsuda, T; Yamagishi, M; Yoshida, T, 2018) |
| "Amiodarone was then tested and simulations were performed under repeated exposure conditions in HepaRG." | 1.46 | Practical use of the Virtual Cell Based Assay: Simulation of repeated exposure experiments in liver cell lines. ( Gerloff, K; Horvat, T; Mennecozzi, M; Paini, A; Palosaari, T; Sala Benito, JV; Worth, A, 2017) |
| "Amiodarone is a widely used potent antiarrhythmic for the treatment of cardiac disease; however, its use is often discontinued due to numerous adverse effects, including hepatotoxicity." | 1.43 | The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity. ( Bryant, MS; Guo, L; Ning, B; Ren, Z; Wu, Q; Xuan, J, 2016) |
| "Amiodarone can cause severe elevation in liver enzymes." | 1.43 | Hepatic Dysfunction in Patients Receiving Intravenous Amiodarone. ( Graham, DY; Hashmi, A; Keswani, NR; Kim, S, 2016) |
| "Phospholipidosis (PLD), an abnormal accumulation of phospholipids within tissues, is observed during the preclinical testing of many pharmaceutical drugs." | 1.38 | Comparison of urinary and serum levels of di-22:6-bis(monoacylglycerol)phosphate as noninvasive biomarkers of phospholipidosis in rats. ( Colatsky, T; Mans, D; Rosenzweig, BA; Shea, K; Stewart, S; Thompson, KL; Zhang, J, 2012) |
| " The increase in ALT activity in AMD/LPS cotreatment showed a clear dose-response relationship with AMD as well as LPS." | 1.38 | Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha. ( Ganey, PE; Harkema, JR; Jones, AD; Lu, J; Roth, RA, 2012) |
| "Hepatotoxicity due to intravenous amiodarone (HIVAD) is a rare side effect with a distinct pattern of enzyme disturbances compared to liver damage from oral amiodarone." | 1.37 | Acute amiodarone liver toxicity likely due to ischemic hepatitis. ( Fried, M; Gluck, N; Porat, R, 2011) |
| " Although oral long-term use of the drug is frequently complicated by an asymptomatic rise in serum aminotransferase concentrations, acute hepatotoxicity during intravenous loading is much less frequent and potentially fatal." | 1.37 | Acute liver injury after intravenous amiodarone: a case report. ( Aprà, F; Elia, F; Ferrari, G; Riva, A; Verhovez, A, 2011) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| "Amiodarone is a lipophilic drug that concentrates in the liver and usually, over a period of time, leads to toxicity related to drug accumulation." | 1.35 | Drug-induced steatohepatitis leading to cirrhosis: long-term toxicity of amiodarone use. ( Chang, C; Fiel, MI; Raja, K; Thung, SN, 2009) |
| "Amiodarone is a class III antiarrhythmic agent with a long half-life which is used to control atrial and ventricular arrhythmias, including atrial flutter and fibrillation." | 1.35 | Hepatotoxicity after intravenous amiodarone. ( Buonocore, S; Cataldi, A; Gonella, D; Odetti, P; Robutti, N; Siri, M, 2008) |
| "Amiodarone chlorhydrate is a diiodated benzofuran derivative, and it is used to treat cardiac rhythm abnormalities." | 1.34 | Amiodarone-induced hepatitis and polyneuropathy. ( Kang, DY; Kang, HM; Kang, YS; Kim, SH; Lee, BS; Lee, HY; Seong, JK, 2007) |
| " The effect of the three least toxic amiodarone analogs on the human ether-a-go-go-related gene (hERG) channel was compared with amiodarone." | 1.33 | Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives. ( Brecht, K; Follath, F; Ha, HR; Konrad, D; Krähenbühl, S; Thomet, U; Török, M; Waldhauser, KM, 2006) |
| "Amiodarone induced hepatomegaly, hepatocyte microvesicular lipid accumulation, and a significant decrease in serum triglycerides and glucose." | 1.32 | Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation. ( Hanniman, EA; McCarthy, TC; Pollak, PT; Sinal, CJ, 2004) |
| "Amiodarone treatment increased significantly the liver-conjugated diene (P<0." | 1.32 | Silymarin and vitamin E reduce amiodarone-induced lysosomal phospholipidosis in rats. ( Agoston, M; Blázovics, A; Fehér, E; Fehér, J; Hagymási, K; Orosz, Z; Orsi, F; Vereckei, A, 2003) |
| "Amiodarone is an antiarrhythmic drug widely used to treat a variety of supraventricular and ventricular arrhythmias." | 1.30 | [Pseudo-alcoholic hepatitis and cirrhosis caused by amiodarone (Cordarone)]. ( Belaiche, J; Lamproye, A; Larrey, D; Ramos, J, 1998) |
| "Noncardiovascular adverse effects associated with amiodarone result in substantial morbidity." | 1.29 | Risk factors for the development of specific noncardiovascular adverse effects associated with amiodarone. ( Follin, SL; Ordelova, A; Tisdale, JE; Webb, CR, 1995) |
| "Amiodarone is an antiarrhythmic agent very often used in clinical practice in spite of its large array of adverse effects." | 1.29 | [Acute hepatitis caused by intravenous amiodarone]. ( Arcusa Gavalda, R; Goma Masip, F; Paniagua Clusells, J; Pons Masanes, S; Soler Masana, JM, 1996) |
| "Amiodarone was then reintroduced and four years later, the patient developed hepatomegaly, worsening liver biochemistry and histopathological changes consistent with early cirrhosis." | 1.28 | Hepatotoxicity of amiodarone. ( Jeyamalar, R; Kannan, P; Pathmanathan, R; Wong, D, 1992) |
| " The mode of administration and the dosage of the drug should be re-considered." | 1.28 | Acute amiodarone-induced hepatitis. ( Gabriel, P; Kalantzis, N; Mouzas, J; Tiniakos, D; Tiniakos, G; Tsigas, D, 1991) |
| " The mean maintenance dosage was 7." | 1.28 | Long-term follow-up of amiodarone therapy in the young: continued efficacy, unimpaired growth, moderate side effects. ( Garson, A; Guccione, P; Paul, T, 1990) |
| "In amiodarone-treated patients, the major findings were as follows: a 50% incidence of hepatic dysfunction with a tenfold increase in concentrations of serum glutamic-oxaloacetic transaminase and serum glutamic-pyruvic transaminase; a 25% incidence of pulmonary dysfunction necessitating a fourfold increase in the number of days of ventilator support; and a 19% incidence of low cardiac output syndrome with two deaths." | 1.28 | Amiodarone-induced complications after cardiac operation for obstructive hypertrophic cardiomyopathy. ( Clark, RE; Kupferschmid, JP; Leon, MB; McIntosh, CL; Rosengart, TK, 1989) |
| "The amiodarone was withdrawn." | 1.27 | Neuropathy and fatal hepatitis in a patient receiving amiodarone. ( Hole, DW; Lim, PK; Storey, GC; Trewby, PN, 1984) |
| "The antiarrhythmic agent amiodarone is associated with numerous adverse effects, but clinically significant liver disease is rare." | 1.27 | Fatal amiodarone hepatoxicity. ( Briscoe, GW; Gilinsky, NH; Kuo, CS, 1988) |
| " Daily dosage was 200 mg in 2 cases, 400 mg then 200 mg in the third one, and duration of therapy ranged between 36 and 60 months." | 1.27 | Chronic liver disease after low daily doses of amiodarone. Report of three cases. ( Babany, G; Carcone, B; Dhumeaux, D; Mallat, A; Saint-Marc Girardin, MF; Zafrani, ES, 1986) |
| " These findings suggest that both toxic and hypersensitivity liver injury can occur in response to amiodarone." | 1.27 | Amiodarone hepatotoxicity. A clinicopathologic study of five patients. ( Barwick, KW; Batsford, WP; Enriquez, R; Helzberg, J; Josephson, ME; Riely, CA; Rigas, B; Rosenfeld, LE, 1986) |
| "Amiodarone is a cardiac antiarrhythmic agent now undergoing clinical trials in the United States." | 1.27 | Dense liver in a 72-year-old woman with congestive heart failure. ( Duncan-Myers, J; Jones, WP; Shin, MS; Stanley, RJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (20.65) | 18.7374 |
| 1990's | 24 (15.48) | 18.2507 |
| 2000's | 29 (18.71) | 29.6817 |
| 2010's | 60 (38.71) | 24.3611 |
| 2020's | 10 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Chen, M | 2 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 3 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 1 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Wei, H | 1 |
| Li, AP | 1 |
| Huang, YL | 1 |
| De Gregorio, C | 1 |
| Silva, V | 1 |
| Elorza, ÁA | 1 |
| Léniz, P | 1 |
| Aliaga-Tobar, V | 1 |
| Maracaja-Coutinho, V | 1 |
| Budini, M | 1 |
| Ezquer, F | 1 |
| Ezquer, M | 1 |
| Nagai, H | 1 |
| Amemiya, T | 1 |
| Suzuki, H | 1 |
| Nagata, T | 1 |
| Takata, K | 1 |
| Shakado, S | 1 |
| Hirai, F | 1 |
| Kupnovytska, I | 1 |
| Virstiuk, N | 1 |
| Danyliuk, O | 1 |
| Luchko, O | 1 |
| Kocherzhat, O | 1 |
| Kim, G | 1 |
| Choi, HK | 1 |
| Lee, H | 1 |
| Moon, KS | 1 |
| Oh, JH | 1 |
| Lee, J | 1 |
| Shin, JG | 1 |
| Kim, DH | 1 |
| Wandrer, F | 1 |
| Frangež, Ž | 1 |
| Liebig, S | 1 |
| John, K | 1 |
| Vondran, F | 1 |
| Wedemeyer, H | 2 |
| Veltmann, C | 1 |
| Pfeffer, TJ | 1 |
| Shibolet, O | 1 |
| Schulze-Osthoff, K | 1 |
| Simon, HU | 1 |
| Bantel, H | 1 |
| El-Khatib, L | 1 |
| Alrayes, H | 1 |
| Sallam, O | 1 |
| Elbanna, A | 1 |
| Brecklinghaus, T | 1 |
| Wu, IU | 1 |
| Tsai, JH | 1 |
| Ho, CM | 1 |
| Ibrahim Fouad, G | 1 |
| R Mousa, M | 1 |
| Tsuda, T | 1 |
| Tada, H | 1 |
| Tanaka, Y | 1 |
| Nishida, N | 1 |
| Yoshida, T | 1 |
| Sawada, T | 1 |
| Sakata, K | 1 |
| Hayashi, K | 1 |
| Kawashiri, MA | 1 |
| Oyama, T | 1 |
| Sasaki, M | 1 |
| Kurose, N | 1 |
| Yamagishi, M | 1 |
| Keng, LT | 1 |
| Liao, MT | 1 |
| Grimaldi-Bensouda, L | 1 |
| Wiegand, J | 1 |
| Lohse, AW | 1 |
| Benichou, J | 1 |
| Rossignol, M | 1 |
| Larrey, D | 2 |
| Abenhaim, L | 1 |
| Poynard, T | 1 |
| Schott, E | 1 |
| Ye, JH | 1 |
| Ho, YF | 2 |
| On, AW | 1 |
| Chen, WW | 1 |
| Huang, YM | 1 |
| Huang, WI | 1 |
| Tang, YW | 1 |
| Chou, HY | 1 |
| Chu, JS | 1 |
| Lee, PI | 1 |
| Haddad, FG | 1 |
| Mulrooney, S | 1 |
| Cherchi, M | 1 |
| Salmón, Z | 1 |
| Ortiz, F | 1 |
| Riancho, JA | 1 |
| Xu, Q | 1 |
| Liu, L | 1 |
| Vu, H | 1 |
| Kuhls, M | 1 |
| Aslamkhan, AG | 1 |
| Liaw, A | 1 |
| Yu, Y | 1 |
| Kaczor, A | 1 |
| Ruth, M | 1 |
| Wei, C | 1 |
| Imredy, J | 1 |
| Lebron, J | 1 |
| Pearson, K | 1 |
| Gonzalez, R | 1 |
| Mitra, K | 1 |
| Sistare, FD | 1 |
| Connolly, M | 1 |
| Menown, IB | 1 |
| Hussey, S | 1 |
| Cinnamond, N | 1 |
| Damani, L | 1 |
| Lu, J | 2 |
| Roth, RA | 2 |
| Malle, E | 1 |
| Ganey, PE | 2 |
| Cho, YS | 1 |
| Han, JH | 1 |
| Chae, HB | 1 |
| Kim, JS | 1 |
| Kang, KM | 1 |
| Park, SM | 1 |
| Lim, JC | 1 |
| Kim, BB | 1 |
| Kim, DM | 1 |
| Choi, DH | 1 |
| Chung, JW | 1 |
| Koh, YY | 1 |
| Chang, KS | 1 |
| Hong, SP | 1 |
| Ul Rehman, S | 1 |
| Siddiqui, N | 1 |
| Khan, NS | 1 |
| Sobia, R | 1 |
| Assaly, R | 1 |
| Vitins, AP | 2 |
| Kienhuis, AS | 2 |
| Speksnijder, EN | 1 |
| Roodbergen, M | 1 |
| Luijten, M | 1 |
| van der Ven, LT | 2 |
| Borlak, J | 1 |
| Chougule, A | 1 |
| Singh, PK | 1 |
| Driessen, M | 1 |
| Pennings, JL | 1 |
| Water, Bv | 1 |
| Mudalel, ML | 1 |
| Dave, KP | 1 |
| Hummel, JP | 1 |
| Solga, SF | 1 |
| Takai, S | 1 |
| Oda, S | 1 |
| Tsuneyama, K | 1 |
| Fukami, T | 2 |
| Nakajima, M | 2 |
| Yokoi, T | 2 |
| Prill, S | 1 |
| Bavli, D | 1 |
| Levy, G | 1 |
| Ezra, E | 1 |
| Schmälzlin, E | 1 |
| Jaeger, MS | 1 |
| Schwarz, M | 1 |
| Duschl, C | 1 |
| Cohen, M | 1 |
| Nahmias, Y | 1 |
| Stratton, A | 1 |
| Fenderson, J | 1 |
| Kenny, P | 1 |
| Helman, DL | 1 |
| Schumacher, JD | 1 |
| Guo, GL | 1 |
| Kenzaka, T | 1 |
| Arif, SA | 1 |
| Drury, R | 1 |
| Ader, P | 1 |
| Xuan, J | 2 |
| Chen, S | 1 |
| Ning, B | 2 |
| Tolleson, WH | 1 |
| Guo, L | 2 |
| Hashmi, A | 1 |
| Keswani, NR | 1 |
| Kim, S | 1 |
| Graham, DY | 1 |
| Wu, Q | 1 |
| Ren, Z | 1 |
| Bryant, MS | 1 |
| Paini, A | 1 |
| Mennecozzi, M | 1 |
| Horvat, T | 1 |
| Gerloff, K | 1 |
| Palosaari, T | 1 |
| Sala Benito, JV | 1 |
| Worth, A | 1 |
| Ali, I | 1 |
| Welch, MA | 1 |
| Lu, Y | 1 |
| Swaan, PW | 1 |
| Brouwer, KLR | 1 |
| Rankin, S | 1 |
| Elder, DH | 1 |
| Ogston, S | 1 |
| George, J | 1 |
| Lang, CC | 1 |
| Choy, AM | 1 |
| Babatin, M | 1 |
| Lee, SS | 1 |
| Pollak, PT | 6 |
| Arkun, A | 1 |
| Van Deusen, SK | 1 |
| Grau, T | 1 |
| Birkhahn, RH | 1 |
| Jamshidzadeh, A | 1 |
| Baghban, M | 1 |
| Azarpira, N | 1 |
| Mohammadi Bardbori, A | 1 |
| Niknahad, H | 1 |
| Li, L | 1 |
| Yang, J | 1 |
| Ding, JW | 1 |
| Llanos, L | 1 |
| Moreu, R | 1 |
| Peiró, AM | 1 |
| Pascual, S | 1 |
| Francés, R | 1 |
| Such, J | 1 |
| Horga, JF | 1 |
| Pérez-Mateo, M | 1 |
| Zapater, P | 1 |
| Cataldi, A | 1 |
| Gonella, D | 1 |
| Robutti, N | 1 |
| Siri, M | 1 |
| Buonocore, S | 1 |
| Odetti, P | 1 |
| Raja, K | 1 |
| Thung, SN | 1 |
| Fiel, MI | 1 |
| Chang, C | 1 |
| Mattar, W | 1 |
| Juliar, B | 1 |
| Gradus-Pizlo, I | 1 |
| Kwo, PY | 1 |
| Gassanov, N | 1 |
| Caglayan, E | 1 |
| Erdmann, E | 1 |
| Er, F | 1 |
| Verhovez, A | 1 |
| Elia, F | 1 |
| Riva, A | 1 |
| Ferrari, G | 1 |
| Aprà, F | 1 |
| Van Summeren, A | 1 |
| Renes, J | 1 |
| Bouwman, FG | 1 |
| Noben, JP | 1 |
| van Delft, JH | 1 |
| Kleinjans, JC | 1 |
| Mariman, EC | 1 |
| Jaeschke, H | 1 |
| McGill, MR | 1 |
| Ramachandran, A | 1 |
| von Vital, JM | 1 |
| Karachristos, A | 1 |
| Singhal, A | 1 |
| Thomas, R | 1 |
| Jain, A | 1 |
| Sung, PS | 1 |
| Yoon, SK | 1 |
| Serviddio, G | 1 |
| Bellanti, F | 1 |
| Giudetti, AM | 1 |
| Gnoni, GV | 1 |
| Capitanio, N | 1 |
| Tamborra, R | 1 |
| Romano, AD | 1 |
| Quinto, M | 1 |
| Blonda, M | 1 |
| Vendemiale, G | 1 |
| Altomare, E | 1 |
| Jones, AD | 1 |
| Harkema, JR | 1 |
| Rao, U | 1 |
| Agarwal, A | 1 |
| Gluck, N | 1 |
| Fried, M | 1 |
| Porat, R | 1 |
| Akbal, E | 1 |
| Batgi, H | 1 |
| Koçak, E | 1 |
| Canatan, T | 1 |
| Köklü, S | 1 |
| Sviridenko, AV | 1 |
| Buniatian, ND | 1 |
| Korsun, LV | 1 |
| Uteshev, DB | 1 |
| Voronkina, MV | 1 |
| Ben Chaabane, N | 1 |
| Hellara, O | 1 |
| Safer, L | 1 |
| Melki, W | 1 |
| Bdioui, F | 1 |
| Zakhama, A | 1 |
| Saffar, H | 1 |
| Endo, S | 1 |
| Toyoda, Y | 1 |
| Thompson, KL | 1 |
| Zhang, J | 1 |
| Stewart, S | 1 |
| Rosenzweig, BA | 1 |
| Shea, K | 1 |
| Mans, D | 1 |
| Colatsky, T | 1 |
| Guglin, M | 2 |
| Gregory, SA | 1 |
| Webster, JB | 1 |
| Chapman, GD | 1 |
| Perings, C | 1 |
| Agozzino, F | 1 |
| Picca, M | 1 |
| Pelosi, G | 1 |
| You, YD | 1 |
| Olsson, R | 1 |
| Agoston, M | 1 |
| Orsi, F | 1 |
| Fehér, E | 2 |
| Hagymási, K | 1 |
| Orosz, Z | 1 |
| Blázovics, A | 1 |
| Fehér, J | 2 |
| Vereckei, A | 2 |
| MacFadyen, RJ | 1 |
| Palmer, TJ | 1 |
| Hisamuddin, K | 1 |
| Shafer, SL | 1 |
| Iba-Ba, J | 1 |
| Tilea, M | 1 |
| Balligand, JL | 1 |
| Lefebvre, C | 1 |
| McCarthy, TC | 1 |
| Hanniman, EA | 1 |
| Sinal, CJ | 1 |
| Rätz Bravo, AE | 1 |
| Drewe, J | 1 |
| Schlienger, RG | 1 |
| Krähenbühl, S | 2 |
| Pargger, H | 1 |
| Ummenhofer, W | 1 |
| Desai, KR | 1 |
| Ricaurte, B | 1 |
| Guirguis, A | 1 |
| Taylor, HC | 1 |
| Zabriskie, D | 1 |
| Kum, LC | 1 |
| Chan, WW | 1 |
| Hui, HH | 1 |
| Wong, GW | 1 |
| Ho, SS | 1 |
| Sanderson, JE | 1 |
| Yu, CM | 1 |
| Fung, JW | 1 |
| Waldhauser, KM | 1 |
| Török, M | 1 |
| Ha, HR | 1 |
| Thomet, U | 1 |
| Konrad, D | 1 |
| Brecht, K | 1 |
| Follath, F | 1 |
| Kang, HM | 1 |
| Kang, YS | 1 |
| Kim, SH | 1 |
| Seong, JK | 1 |
| Kang, DY | 1 |
| Lee, HY | 1 |
| Lee, BS | 1 |
| Rizzioli, E | 1 |
| Incasa, E | 1 |
| Gamberini, S | 1 |
| Savelli, S | 1 |
| Zangirolami, A | 1 |
| Tampieri, M | 1 |
| Manfredini, R | 1 |
| Chan, AL | 1 |
| Hsieh, HJ | 1 |
| Hsieh, YA | 1 |
| Lin, SJ | 1 |
| Waxman, HL | 1 |
| Groh, WC | 1 |
| Marchlinski, FE | 1 |
| Buxton, AE | 1 |
| Sadowski, LM | 1 |
| Horowitz, LN | 1 |
| Josephson, ME | 2 |
| Kastor, JA | 1 |
| Lim, PK | 1 |
| Trewby, PN | 1 |
| Storey, GC | 1 |
| Hole, DW | 1 |
| Nauta, IL | 1 |
| Ruland, CM | 1 |
| Hertzberger, DH | 1 |
| Rensing, JB | 1 |
| Poucell, S | 1 |
| Ireton, J | 1 |
| Valencia-Mayoral, P | 1 |
| Downar, E | 1 |
| Larratt, L | 1 |
| Patterson, J | 1 |
| Blendis, L | 1 |
| Phillips, MJ | 1 |
| Simon, JB | 1 |
| Manley, PN | 1 |
| Brien, JF | 1 |
| Armstrong, PW | 1 |
| Tosetti, C | 1 |
| Ongari, M | 1 |
| Evangelisti, A | 1 |
| Lolli, R | 1 |
| Napoli, A | 1 |
| Tisdale, JE | 1 |
| Follin, SL | 1 |
| Ordelova, A | 1 |
| Webb, CR | 1 |
| Richer, M | 1 |
| Robert, S | 1 |
| Rhodes, A | 1 |
| Eastwood, JB | 1 |
| Smith, SA | 1 |
| Muñoz Ruiz, AI | 1 |
| Calvo Elipe, A | 1 |
| Guerrero Vega, E | 1 |
| Gorgojo Martínez, JJ | 1 |
| Vera López, E | 1 |
| Gilsanz Fernández, C | 1 |
| Paniagua Clusells, J | 1 |
| Arcusa Gavalda, R | 1 |
| Goma Masip, F | 1 |
| Pons Masanes, S | 1 |
| Soler Masana, JM | 1 |
| James, PR | 2 |
| Hardman, SM | 1 |
| Tagliamonte, E | 1 |
| Cice, G | 1 |
| Ducceschi, V | 1 |
| Mayer, MS | 1 |
| Iacono, A | 1 |
| Cole, TJ | 1 |
| Proto, AV | 1 |
| Lamproye, A | 1 |
| Ramos, J | 1 |
| Belaiche, J | 1 |
| Breuer, HW | 1 |
| Bossek, W | 1 |
| Haferland, C | 1 |
| Schmidt, M | 1 |
| Neumann, H | 1 |
| Gruszka, J | 1 |
| López-Gómez, D | 1 |
| Nicolás, J | 1 |
| Frigola, JM | 1 |
| Manito, N | 1 |
| Esplugas, E | 1 |
| Jain, D | 1 |
| Bowlus, CL | 1 |
| Anderson, JM | 1 |
| Robert, ME | 1 |
| Luengo, O | 1 |
| Montero, J | 1 |
| Alegre, J | 1 |
| Fernández Sevilla, T | 1 |
| Barrera Groba, C | 1 |
| Jeyamalar, R | 1 |
| Pathmanathan, R | 1 |
| Wong, D | 1 |
| Kannan, P | 1 |
| Fornaciari, G | 1 |
| Monducci, I | 1 |
| Barone, A | 1 |
| Bassi, C | 1 |
| Beltrami, M | 1 |
| Tomasi, C | 1 |
| Sastri, SV | 1 |
| Diaz-Arias, AA | 1 |
| Marshall, JB | 1 |
| Benbassat, C | 1 |
| Shahar, A | 1 |
| György, I | 1 |
| Fóldiák, G | 1 |
| Tóth, M | 1 |
| Toncsev, H | 1 |
| Morelli, S | 1 |
| Guido, V | 1 |
| De Marzio, P | 1 |
| Aguglia, F | 1 |
| Balsano, F | 1 |
| Kalantzis, N | 1 |
| Gabriel, P | 1 |
| Mouzas, J | 1 |
| Tiniakos, D | 1 |
| Tsigas, D | 1 |
| Tiniakos, G | 1 |
| Simon, JP | 1 |
| Zannad, F | 3 |
| Trechot, P | 2 |
| Thisse, JY | 1 |
| Houplon, M | 1 |
| Aliot, E | 1 |
| Kolarski, V | 1 |
| Vladov, V | 1 |
| Guccione, P | 1 |
| Paul, T | 1 |
| Garson, A | 1 |
| Sharma, AD | 1 |
| Carruthers, SG | 1 |
| Lewis, JH | 2 |
| Mullick, F | 2 |
| Ishak, KG | 2 |
| Ranard, RC | 2 |
| Ragsdale, B | 1 |
| Perse, RM | 1 |
| Rusnock, EJ | 1 |
| Wolke, A | 1 |
| Benjamin, SB | 1 |
| Seeff, LB | 2 |
| Stevenson, RN | 1 |
| Nayani, TH | 1 |
| Davies, JR | 1 |
| Young, RA | 1 |
| Mehendale, HM | 1 |
| Flaharty, KK | 1 |
| Chase, SL | 1 |
| Yaghsezian, HM | 1 |
| Rubin, R | 1 |
| Salti, Z | 1 |
| Cloche, P | 1 |
| Weber, P | 1 |
| Houssemand, G | 1 |
| Vollmer, F | 1 |
| Genève, J | 1 |
| Zafrani, ES | 2 |
| Dhumeaux, D | 2 |
| Rigas, B | 2 |
| Kupferschmid, JP | 1 |
| Rosengart, TK | 1 |
| McIntosh, CL | 1 |
| Leon, MB | 1 |
| Clark, RE | 1 |
| Caruso, A | 1 |
| Jackson, LK | 1 |
| Zimmerman, HJ | 1 |
| Willems, AR | 1 |
| Schöttelndreiër, MA | 1 |
| Fossati, C | 1 |
| Adler, M | 1 |
| Ros, P | 1 |
| Cremer, M | 1 |
| Quiriny, M | 1 |
| Henry, JP | 1 |
| Lecocq, E | 1 |
| Morse, RM | 1 |
| Valenzuela, GA | 1 |
| Greenwald, TP | 1 |
| Eulie, PJ | 1 |
| Wesley, RC | 1 |
| McCallum, RW | 1 |
| Giordano, G | 1 |
| Franciosini, MF | 1 |
| Zuanetti, G | 1 |
| Latini, R | 1 |
| Gilinsky, NH | 1 |
| Briscoe, GW | 1 |
| Kuo, CS | 1 |
| Pye, M | 1 |
| Northcote, RJ | 1 |
| Cobbe, SM | 1 |
| Shepherd, NA | 1 |
| Dawson, AM | 1 |
| Crocker, PR | 1 |
| Levison, DA | 1 |
| Aldershvile, J | 1 |
| Hansen, PF | 1 |
| Lupon-Rosés, J | 1 |
| Simó-Canonge, R | 1 |
| Lu-Cortez, L | 1 |
| Permanyer-Miralda, G | 1 |
| Allende-Monclús, H | 1 |
| Gay, G | 1 |
| Netter, P | 1 |
| Roche, JP | 1 |
| de Korwin, JD | 1 |
| Gagey, S | 1 |
| Paille, F | 1 |
| Schmitt, J | 1 |
| Coste, T | 1 |
| Merrouche, Y | 1 |
| Duchatelle, V | 1 |
| Huc, D | 1 |
| Rautureau, J | 1 |
| Babany, G | 1 |
| Mallat, A | 1 |
| Saint-Marc Girardin, MF | 1 |
| Carcone, B | 1 |
| Elving, LD | 1 |
| Hoefnagels, WH | 1 |
| Van Haelst, UJ | 1 |
| Griffioen, G | 1 |
| Janssens, AR | 1 |
| Ruiter, DJ | 1 |
| Rumessen, JJ | 1 |
| Andreasen, PB | 1 |
| Lauterburg, BH | 1 |
| Rosenfeld, LE | 1 |
| Barwick, KW | 1 |
| Enriquez, R | 1 |
| Helzberg, J | 1 |
| Batsford, WP | 1 |
| Riely, CA | 1 |
| Jones, WP | 1 |
| Shin, MS | 1 |
| Stanley, RJ | 1 |
| Duncan-Myers, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients With Atrial Tachyarrhythmias[NCT03413150] | 80 participants (Actual) | Observational | 2007-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 reviews available for amiodarone and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Severe acute hepatitis following intravenous amiodarone : a case report and review of the literature.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Human | 2015 |
Mechanistic review of drug-induced steatohepatitis.
Topics: Amiodarone; Animals; Camptothecin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; F | 2015 |
Amiodarone hepatotoxicity.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Humans; Liver; | 2008 |
[Amiodarone liver toxicity about two cases and review of literature].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Fatal Outcome; Fem | 2004 |
Hepatotoxicity during rapid intravenous loading with amiodarone: Description of three cases and review of the literature.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injur | 2005 |
Fatal amiodarone-induced hepatotoxicity: a case report and literature review.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injur | 2008 |
[Acute hepatotoxicity from amiodarone].
Topics: Acute Disease; Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Necros | 1995 |
[Acute hepatitis following amiodarone administration].
Topics: Acute Disease; Amiodarone; Chemical and Drug Induced Liver Injury; Electrocardiography; Humans; Male | 1997 |
[The use of oral amiodarone as a chronic treatment in a patient with prior fulminant hepatitis due to intravenous amiodarone].
Topics: Acute Disease; Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced L | 1999 |
[Possibilities of antioxidant therapy in the prevention of side effects of amiodarone].
Topics: Amiodarone; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclini | 1991 |
[Amiodarone and the liver].
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Humans; Liver; | 1990 |
Histopathologic analysis of suspected amiodarone hepatotoxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Chemical and Drug Induced Liver Injury; Diag | 1990 |
Hepatotoxicity associated with amiodarone therapy.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Biopsy; Chemical and Drug Induced Liver Injury; Half-Life; H | 1989 |
[A case of cholestatic hepatitis caused by amiodarone].
Topics: Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Male; Time Factors | 1989 |
Amiodarone-induced liver disease.
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Humans | 1989 |
[Amiodarone and its side effects].
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Corneal Diseases; Humans; Lung Diseases; Periphe | 1988 |
[Collateral effects of an anti-arrhythmic agent: amiodarone].
Topics: Amiodarone; Benzofurans; Chemical and Drug Induced Liver Injury; Eye Diseases; Humans; Hyperthyroidi | 1985 |
[Drug-induced hepatic lesions].
Topics: Adenoma; Amiodarone; Amphetamines; Antineoplastic Agents; Budd-Chiari Syndrome; Carcinoma, Hepatocel | 1986 |
[Drug damage to the liver: role of reactive metabolites and pharmacokinetics].
Topics: Acetaminophen; Amiodarone; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adv | 1985 |
135 other studies available for amiodarone and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Permeabilized Cryopreserved Human Hepatocytes as an Exogenous Metabolic System in a Novel Metabolism-Dependent Cytotoxicity Assay for the Evaluation of Metabolic Activation and Detoxification of Drugs Associated with Drug-Induced Liver Injuries: Results w
Topics: Acetaminophen; Activation, Metabolic; Amiodarone; Chemical and Drug Induced Liver Injury; Cyclophosp | 2022 |
Administration of Secretome Derived from Human Mesenchymal Stem Cells Induces Hepatoprotective Effects in Models of Idiosyncratic Drug-Induced Liver Injury Caused by Amiodarone or Tamoxifen.
Topics: Amiodarone; Animals; Chemical and Drug Induced Liver Injury; Fatty Liver; Humans; Immunologic Factor | 2023 |
Risk factors for amiodarone-induced liver injury: A retrospective analysis of medical records.
Topics: Amiodarone; C-Reactive Protein; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Li | 2023 |
Amiodarone-induced hepatotoxicity.
Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Humans | 2023 |
[HEPATOCELLULAR TOXICITY IN THE BACKGROUND OF AMIODARON-INDUCED THYROID DYSFUNCTION IN PATIENTS WITH ATRIAL FIBRILLATION].
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injury; Hum | 2019 |
Increased hepatic acylcarnitines after oral administration of amiodarone in rats.
Topics: Administration, Oral; Amiodarone; Animals; Biomarkers; Carnitine; Chemical and Drug Induced Liver In | 2020 |
Autophagy alleviates amiodarone-induced hepatotoxicity.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Apoptosis; Autophagy; Cell Survival; Cells, Cultured; Chem | 2020 |
Quinidine hypersensitivity: a side effect of a forgotten antiarrhythmic.
Topics: Acute Disease; Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Dru | 2020 |
Role of autophagy in drug induced liver injury.
Topics: Amiodarone; Autophagy; Chemical and Drug Induced Liver Injury; Humans | 2020 |
Fatal acute-on-chronic liver failure in amiodarone-related steatohepatitis: a case report.
Topics: Acute-On-Chronic Liver Failure; Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced | 2021 |
The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats.
Topics: Alanine Transaminase; Amiodarone; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cyt | 2021 |
Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports.
Topics: Aged; Alanine Transaminase; Amiodarone; Anti-Arrhythmia Agents; Aspartate Aminotransferases; Chemica | 2018 |
Amiodarone-induced hepatic and pulmonary toxicity.
Topics: Aged, 80 and over; Amiodarone; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Fata | 2018 |
Dronedarone, amiodarone and other antiarrhythmic drugs, and acute liver injuries: a case-referent study.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Case-Control Studies; Chemical and Drug Induced Liver Inju | 2018 |
Trends in reporting drug-associated liver injuries in Taiwan: a focus on amiodarone.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Amiodarone; An | 2018 |
Comedication with interacting drugs predisposes amiodarone users in cardiac and surgical intensive care units to acute liver injury: A retrospective analysis.
Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; | 2018 |
A Shiny Liver!
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induce | 2019 |
Severe liver toxicity by intravenous amiodarone.
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Infusions, Intravenous; Male; Middle Age | 2019 |
Can Galactose Be Converted to Glucose in HepG2 Cells? Improving the
Topics: Amiodarone; Benzbromarone; Chemical and Drug Induced Liver Injury; Galactose; Glucose; Hep G2 Cells; | 2019 |
The dronedarone shared-care clinical model and database: a coordinated paradigm to optimize management of evolving clinical recommendations.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical an | 2013 |
Roles of the hemostatic system and neutrophils in liver injury from co-exposure to amiodarone and lipopolysaccharide.
Topics: Amiodarone; Animals; Anticoagulants; Blood Coagulation; Chemical and Drug Induced Liver Injury; Fibr | 2013 |
[A case of simultaneously occurred amiodarone-induced hepatitis and hypothyroidism].
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Female; Fibrosis; Hu | 2013 |
Amiodarone toxicity showing high liver density on CT scan with normal liver function and plasma amiodarone levels in a long-term amiodarone user.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injur | 2014 |
Multisystem side effects of amiodarone.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injury; Fac | 2015 |
Mechanisms of amiodarone and valproic acid induced liver steatosis in mouse in vivo act as a template for other hepatotoxicity models.
Topics: Amiodarone; Animals; Binding Sites; Cell Line; Chemical and Drug Induced Liver Injury; Disease Model | 2014 |
How useful are clinical liver function tests in in vitro human hepatotoxicity assays?
Topics: Acetaminophen; Alanine Transaminase; Albumins; Alkaline Phosphatase; Amiodarone; Aspartate Aminotran | 2014 |
A transcriptomics-based hepatotoxicity comparison between the zebrafish embryo and established human and rodent in vitro and in vivo models using cyclosporine A, amiodarone and acetaminophen.
Topics: Acetaminophen; Amiodarone; Analgesics, Non-Narcotic; Animals; Anti-Arrhythmia Agents; Chemical and D | 2015 |
N-acetylcysteine treats intravenous amiodarone induced liver injury.
Topics: Acetylcysteine; Aged; Amiodarone; Anti-Arrhythmia Agents; Antioxidants; Biomarkers; Chemical and Dru | 2015 |
Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism.
Topics: Alanine Transaminase; Amiodarone; Animals; Chemical and Drug Induced Liver Injury; Dexamethasone; Ga | 2016 |
Real-time monitoring of oxygen uptake in hepatic bioreactor shows CYP450-independent mitochondrial toxicity of acetaminophen and amiodarone.
Topics: Acetaminophen; Activation, Metabolic; Amiodarone; Analgesics, Non-Narcotic; Anti-Arrhythmia Agents; | 2016 |
Hepatic computed tomography changes caused by amiodarone.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induce | 2015 |
Impact of Food and Drug Administration hepatotoxicity warning on prescribing and monitoring of dronedarone in a tertiary teaching hospital.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver | 2015 |
Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity.
Topics: Amiodarone; Antimalarials; Antipsychotic Agents; Cell Line; Chemical and Drug Induced Liver Injury; | 2016 |
Hepatic Dysfunction in Patients Receiving Intravenous Amiodarone.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver | 2016 |
The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.
Topics: Activation, Metabolic; Amiodarone; Anti-Arrhythmia Agents; Benzoflavones; Cell Survival; Chemical an | 2016 |
Practical use of the Virtual Cell Based Assay: Simulation of repeated exposure experiments in liver cell lines.
Topics: Amiodarone; Animal Testing Alternatives; Caffeine; Cell Line; Cell Survival; Chemical and Drug Induc | 2017 |
Identification of novel MRP3 inhibitors based on computational models and validation using an in vitro membrane vesicle assay.
Topics: Aminoglycosides; Amiodarone; Bayes Theorem; Biological Transport; Cell Survival; Chemical and Drug I | 2017 |
Population-level incidence and monitoring of adverse drug reactions with long-term amiodarone therapy.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; | 2017 |
Hepatic dysfunction and neurotoxicity in a patient receiving long-term low-dose amiodarone therapy.
Topics: Aged, 80 and over; Amiodarone; Ammonia; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Dr | 2010 |
Effects of tomato extract on oxidative stress induced toxicity in different organs of rats.
Topics: Acetaminophen; Amiodarone; Analgesics, Non-Narcotic; Animals; Anti-Arrhythmia Agents; Chemical and D | 2008 |
[Acute amiodarone-induced hepatotoxicity in a patient].
Topics: Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reac | 2008 |
Causality assessment of liver injury after chronic oral amiodarone intake.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Bayes Theo | 2009 |
Hepatotoxicity after intravenous amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injur | 2008 |
Drug-induced steatohepatitis leading to cirrhosis: long-term toxicity of amiodarone use.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Biopsy; Chemical and Drug Induced Liver Injury; Diagnosis, | 2009 |
Amiodarone hepatotoxicity in the context of the metabolic syndrome and right-sided heart failure.
Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Amiodarone; Anti-Arrhythmia Agents; Aspartate | 2009 |
How toxic is amiodarone to the liver?
Topics: Alanine Transaminase; Amiodarone; Anti-Arrhythmia Agents; Aspartate Aminotransferases; Chemical and | 2010 |
[Amiodarone-induced liver dysfunctions].
Topics: Alanine Transaminase; Amiodarone; Anti-Arrhythmia Agents; Aspartate Aminotransferases; Atrial Fibril | 2010 |
Acute liver injury after intravenous amiodarone: a case report.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induce | 2011 |
Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells.
Topics: Acetaminophen; Amiodarone; Blotting, Western; Cell Survival; Chemical and Drug Induced Liver Injury; | 2011 |
In brief: FDA warning on dronedarone (Multaq).
Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Dronedarone; Drug Labeli | 2011 |
Pathophysiological relevance of proteomics investigations of drug-induced hepatotoxicity in HepG2 cells.
Topics: Acetaminophen; Amiodarone; Chemical and Drug Induced Liver Injury; Cyclosporine; Gene Expression Reg | 2011 |
Acute amiodarone hepatotoxicity after liver transplantation.
Topics: Acute Disease; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Carcinoma, Hepatocellular; C | 2011 |
Amiodarone hepatotoxicity.
Topics: Acute Disease; Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Hypertension; Male; | 2012 |
Dronedarone: liver damage and cardiac disorders. Negative harm-benefit balance.
Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Dronedarone; Heart Disea | 2011 |
Mitochondrial oxidative stress and respiratory chain dysfunction account for liver toxicity during amiodarone but not dronedarone administration.
Topics: Amiodarone; Animals; Chemical and Drug Induced Liver Injury; Dronedarone; Hydrogen Peroxide; Liver; | 2011 |
Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cell Line, Tumor; Cell Survival; Chemical and Drug Indu | 2012 |
Amiodarone-induced acute hepatotoxicity.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Amiodarone; Anti-Arrhythmia Agents; Bilirubin; Ch | 2012 |
Acute amiodarone liver toxicity likely due to ischemic hepatitis.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Biopsy; Chemical and Drug Induced Liver Injury; Female; He | 2011 |
Low-dose amiodarone-induced fatal liver failure.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Dose- | 2013 |
[Abnormal liver function during therapy with amiodarone in patients with persistent atrial fibrillation].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injur | 2011 |
Cirrhosis with increased density of the liver: amiodarone-induced hepatotoxicity.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Li | 2012 |
Stimulation of human monocytic THP-1 cells by metabolic activation of hepatotoxic drugs.
Topics: Albendazole; Amiodarone; B7-2 Antigen; Biotransformation; Cell Line, Tumor; Chemical and Drug Induce | 2012 |
Comparison of urinary and serum levels of di-22:6-bis(monoacylglycerol)phosphate as noninvasive biomarkers of phospholipidosis in rats.
Topics: Acetaminophen; Amiodarone; Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Histocytoche | 2012 |
Occam's razor and ischemic hepatitis.
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Female; Hepatitis; Humans; Hypotension; Ischemia | 2012 |
Acute hepatitis induced by parenteral amiodarone.
Topics: Acute Disease; Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Dos | 2002 |
[Anti-arrhythmic drug therapy in impaired liver function].
Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Contraindications; Human | 2002 |
Acute hepatitis complicating intravenous amiodarone treatment.
Topics: Acute Disease; Acute Kidney Injury; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; C | 2002 |
Monitoring of hepatic function during amiodarone therapy.
Topics: Administration, Oral; Aged; Amiodarone; Analysis of Variance; Chemical and Drug Induced Liver Injury | 2003 |
Acute hepatitis after parenteral amiodarone.
Topics: Acute Disease; Acute Kidney Injury; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemica | 2003 |
Silymarin and vitamin E reduce amiodarone-induced lysosomal phospholipidosis in rats.
Topics: Amiodarone; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Hepatocytes; Liver Diseas | 2003 |
Rapidly fatal acute amiodarone hepatitis occurring in the context of multiple organ failure.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomyopathy, Dilated; Chemical and Drug | 2003 |
Use of population modeling to define rational monitoring of amiodarone hepatic effects.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biomarkers; Chemical and Drug Induce | 2004 |
Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Blood Glucose; Blotting, Northern; Body Weight; Cell Li | 2004 |
Intravenous amiodarone: offender or bystander?
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Critical Care; Dia | 2005 |
Amiodarone versus sotalol for atrial fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injury; Hum | 2005 |
Simvastatin-amiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity.
Topics: Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Drug Interactions; Humans; Male; Rhabdomyo | 2006 |
Prevalence of amiodarone-related hepatotoxicity in 720 Chinese patients with or without baseline liver dysfunction.
Topics: Alanine Transaminase; Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Fl | 2006 |
Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives.
Topics: Adenosine Triphosphate; Amiodarone; Animals; Annexin A5; Anti-Arrhythmia Agents; Apoptosis; Cell Lin | 2006 |
Amiodarone-induced hepatitis and polyneuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Humans; Liver Cirr | 2007 |
Acute toxic hepatitis after amiodarone intravenous loading.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Electrocardiograph | 2007 |
Amiodarone for control of sustained ventricular tachyarrhythmia: clinical and electrophysiologic effects in 51 patients.
Topics: Adolescent; Adult; Aged; Amiodarone; Benzofurans; Cardiac Pacing, Artificial; Chemical and Drug Indu | 1982 |
Neuropathy and fatal hepatitis in a patient receiving amiodarone.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Chemical and Drug Induced Liver Injury; Humans; | 1984 |
Heart failure and hepatitis in a patient taking tocainide.
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Heart Failure; Humans; Lidocaine; Liver Function | 1984 |
Amiodarone-associated phospholipidosis and fibrosis of the liver. Light, immunohistochemical, and electron microscopic studies.
Topics: Amiodarone; Benzofurans; Biopsy; Chemical and Drug Induced Liver Injury; Cholangitis; Female; Humans | 1984 |
Amiodarone hepatotoxicity simulating alcoholic liver disease.
Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Chemical and Drug Induced Liver Injury; Diagno | 1984 |
Risk factors for the development of specific noncardiovascular adverse effects associated with amiodarone.
Topics: Adult; Age Factors; Aged; Amiodarone; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; | 1995 |
Fatal hepatotoxicity following oral administration of amiodarone.
Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Amiodarone; Aspartate Aminotransfe | 1995 |
Early acute hepatitis with parenteral amiodarone: a toxic effect of the vehicle?
Topics: Acute Disease; Acute Kidney Injury; Administration, Oral; Aged; Amiodarone; Chemical and Drug Induce | 1993 |
[Pancreatitis and inappropriate ADH secretion syndrome associated with amiodarone].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injur | 1996 |
[Acute hepatitis caused by intravenous amiodarone].
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug | 1996 |
Acute hepatitis complicating parenteral amiodarone does not preclude subsequent oral therapy.
Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Ind | 1997 |
[Amiodarone toxicity in a patient with at-risk ventricular arrhythmia].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; He | 1997 |
[Pseudo-alcoholic hepatitis and cirrhosis caused by amiodarone (Cordarone)].
Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Humans; Liver Cirrhosis; | 1998 |
Amiodarone-induced severe hepatitis mediated by immunological mechanisms.
Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Heart Failure; Humans; M | 1998 |
Granular cells as a marker of early amiodarone hepatotoxicity.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Biopsy, Needle; Chemical and Drug Induced Liver Injury; H | 2000 |
[Toxic hepatitis caused by intravenous amiodarone].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Female; Humans; In | 2000 |
Intravenous amiodarone in intensive care: time for a reappraisal?
Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Humans; Intensive Care U | 2001 |
Hepatotoxicity of amiodarone.
Topics: Aged; Amiodarone; Biopsy; Chemical and Drug Induced Liver Injury; Coronary Disease; Follow-Up Studie | 1992 |
Amiodarone-induced acute hepatitis: case report.
Topics: Acute Disease; Amiodarone; Chemical and Drug Induced Liver Injury; Female; Humans; Middle Aged | 1992 |
Can pancreatitis be associated with amiodarone hepatotoxicity?
Topics: Aged; Amiodarone; Amylases; Chemical and Drug Induced Liver Injury; Humans; Lipase; Liver Cirrhosis; | 1990 |
[Acute fulminant hepatic failure after short-term amiodarone].
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Male; Middle Aged | 1991 |
Early hepatitis during intravenous amiodarone administration.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Humans; Infusions, I | 1991 |
Acute amiodarone-induced hepatitis.
Topics: Adult; Amiodarone; Atrial Fibrillation; Biopsy; Chemical and Drug Induced Liver Injury; Humans; Live | 1991 |
Acute hepatitis after a loading dose of intravenous amiodarone.
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Infusions, Intravenous; Male; Middle Age | 1990 |
Long-term follow-up of amiodarone therapy in the young: continued efficacy, unimpaired growth, moderate side effects.
Topics: Adolescent; Adult; Amiodarone; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Child; | 1990 |
Relation of amiodarone hepatic and pulmonary toxicity to serum drug concentrations and superoxide dismutase activity.
Topics: Alanine Transaminase; Amiodarone; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injur | 1990 |
Acute hepatic dysfunction following parenteral amiodarone administration.
Topics: Acute Disease; Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Infusions, Intravenous; M | 1989 |
Effects of short-term and long-term administration of amiodarone on hepatobiliary function in male rats.
Topics: Amiodarone; Animals; Bile; Body Weight; Chemical and Drug Induced Liver Injury; Diet; Enzymes; Male; | 1989 |
The evolving spectrum of amiodarone hepatotoxicity.
Topics: Acute Disease; Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Injections, Intravenous | 1989 |
Amiodarone-induced complications after cardiac operation for obstructive hypertrophic cardiomyopathy.
Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Cardiac Output, Low; Cardiomyopathy, Hypertrophic; Chemical | 1989 |
Amiodarone hepatotoxicity: prevalence and clinicopathologic correlations among 104 patients.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amiodarone; Aspartate Aminotransferases; Chemical and Dr | 1989 |
Amiodarone-induced liver toxicity.
Topics: Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Hyperbilirubi | 1988 |
[Digitalis intoxication in the presence of amiodarone-induced acute hepatitis].
Topics: Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Digoxin; Drug Interactions; Humans; Liver; | 1988 |
Fatal amiodarone hepatoxicity.
Topics: Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Radiography | 1988 |
Acute hepatitis after parenteral amiodarone administration.
Topics: Acute Disease; Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Female; Humans; Infusions, | 1988 |
Granular cells as a marker of early amiodarone hepatotoxicity: a pathological and analytical study.
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Cytoplasmic Granules; Female; Humans; Iodine; Li | 1987 |
[Amiodarone and liver damage].
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Humans | 1987 |
Probable early acute hepatitis with parenteral amiodarone.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Biopsy; Chemical and Drug Induced Liver Injury; | 1986 |
A case of amiodarone-induced hyperthyroidism and hepatitis: results of clinical laboratory and histological tests.
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Hyperthyroidism; Liver; Male; Middle Age | 1986 |
[Acute hepatitis attributed to amiodarone].
Topics: Acute Disease; Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Male; Middle Aged | 1986 |
[Chronic hepatitis associated with the intake of amiodarone].
Topics: Aged; Aged, 80 and over; Amiodarone; Chemical and Drug Induced Liver Injury; Chronic Disease; Female | 1986 |
Chronic liver disease after low daily doses of amiodarone. Report of three cases.
Topics: Aged; Aged, 80 and over; Amiodarone; Angina Pectoris; Chemical and Drug Induced Liver Injury; Chroni | 1986 |
Amiodarone hepatotoxicity.
Topics: Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Female; Humans; Lipidoses; Liver; Male; Mi | 1986 |
[Amiodarone (Cordarone) induced liver damage].
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Humans | 1986 |
Amiodarone hepatotoxicity. A clinicopathologic study of five patients.
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Amiodarone; Aspartate Aminotransferases; Benzofura | 1986 |
Dense liver in a 72-year-old woman with congestive heart failure.
Topics: Aged; Amiodarone; Benzofurans; Chemical and Drug Induced Liver Injury; Female; Heart Failure; Humans | 1985 |