amiodarone has been researched along with Acute Hepatic Failure in 11 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe a challenging patient case in which dronedarone was selected for a patient with atrial fibrillation and heart failure; the drug may have been associated with worsening heart failure, leading to acute renal and hepatic failure." | 7.76 | Worsening heart failure in the setting of dronedarone initiation. ( Coons, JC; Plauger, KM; Seybert, AL; Sokos, GG, 2010) |
| "Acute hepatic failure is a rare and potentially lethal complication of propylthiouracil (PTU) use for hyperthyroidism." | 7.72 | Successful treatment of hyperthyroidism with amiodarone in a patient with propylthiouracil-induced acute hepatic failure. ( Arteaga, E; Brusco, F; González, G; Soto, N, 2004) |
| "To describe a challenging patient case in which dronedarone was selected for a patient with atrial fibrillation and heart failure; the drug may have been associated with worsening heart failure, leading to acute renal and hepatic failure." | 3.76 | Worsening heart failure in the setting of dronedarone initiation. ( Coons, JC; Plauger, KM; Seybert, AL; Sokos, GG, 2010) |
| "Acute hepatic failure is a rare and potentially lethal complication of propylthiouracil (PTU) use for hyperthyroidism." | 3.72 | Successful treatment of hyperthyroidism with amiodarone in a patient with propylthiouracil-induced acute hepatic failure. ( Arteaga, E; Brusco, F; González, G; Soto, N, 2004) |
| "Amiodarone was immediately withheld, and N-acetylcysteine (NAC) was initiated." | 2.58 | Acute liver failure with amiodarone infusion: A case report and systematic review. ( Attar, BM; Demetria, M; Devani, K; Jaiswal, P; Jaiswal, R; Patel, D; Szynkarek, R; Wang, Y; Yap, JE, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 9 (81.82) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Balint Ilie, C | 1 |
| Montón Dito, JM | 1 |
| Esteban Molina, A | 1 |
| Jaiswal, P | 1 |
| Attar, BM | 1 |
| Yap, JE | 1 |
| Devani, K | 1 |
| Jaiswal, R | 1 |
| Wang, Y | 1 |
| Szynkarek, R | 1 |
| Patel, D | 1 |
| Demetria, M | 1 |
| Nicot, F | 1 |
| Procopi, N | 1 |
| Nguyen, LS | 1 |
| Li, JG | 1 |
| Yang, TC | 1 |
| Yu, DM | 1 |
| Ren, TH | 1 |
| Coons, JC | 1 |
| Plauger, KM | 1 |
| Seybert, AL | 1 |
| Sokos, GG | 1 |
| Joghetaei, N | 1 |
| Weirich, G | 1 |
| Huber, W | 1 |
| Büchler, P | 1 |
| Estner, H | 1 |
| Akbal, E | 1 |
| Batgi, H | 1 |
| Koçak, E | 1 |
| Canatan, T | 1 |
| Köklü, S | 1 |
| Capucci, A | 1 |
| Guerra, F | 1 |
| Antenucci, C | 1 |
| Antonicelli, R | 1 |
| Bocconcelli, P | 1 |
| Boriani, G | 1 |
| Busacca, P | 1 |
| Ciampani, N | 1 |
| Della Casa, S | 1 |
| Gabrielli, D | 1 |
| Galvani, M | 1 |
| Margheri, M | 1 |
| Melandri, F | 1 |
| Modena, MG | 1 |
| Perna, GP | 1 |
| Pieri, P | 1 |
| Piovaccari, G | 1 |
| Pozzolini, A | 1 |
| Rapezzi, C | 1 |
| Villani, GQ | 1 |
| De Ponti, F | 1 |
| Mugelli, A | 1 |
| Grecian, R | 1 |
| Ainslie, M | 1 |
| Brusco, F | 1 |
| González, G | 1 |
| Soto, N | 1 |
| Arteaga, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients With Atrial Tachyarrhythmias[NCT03413150] | 80 participants (Actual) | Observational | 2007-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for amiodarone and Acute Hepatic Failure
| Article | Year |
|---|---|
Acute liver failure with amiodarone infusion: A case report and systematic review.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Female; Hospitalization; Humans; Infusions, Intravenous; L | 2018 |
[Dronedarone: a real innovation or a mere second-best choice? How to find the way among guidelines, regulatory agencies and daily clinical practice].
Topics: Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Heart Rate; Humans | 2012 |
9 other studies available for amiodarone and Acute Hepatic Failure
| Article | Year |
|---|---|
[Severe acute hepatic failure secondary to amiodarone overdose].
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiovascular Agents; Drug-Related Side Effects and Adverse Rea | 2023 |
Intravenous amiodarone-induced acute liver failure in cardiac surgery intensive care unit.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Critical | 2018 |
Fatal acute liver failure after intravenous amiodarone administration.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Fatal Outcome; Female; Humans; | 2015 |
Worsening heart failure in the setting of dronedarone initiation.
Topics: Acute Kidney Injury; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Progression; D | 2010 |
Acute liver failure associated with dronedarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Biopsy; Dronedarone; Female; Humans; | 2011 |
Low-dose amiodarone-induced fatal liver failure.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Dose- | 2013 |
[Between guidelines and regulatory decisions: the odyssey of dronedarone].
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Drug and Narcotic Control; Evi | 2012 |
Acute hepatic failure following intravenous amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Humans; Infusions, Intravenous; Liver Failure, Acute; Male | 2012 |
Successful treatment of hyperthyroidism with amiodarone in a patient with propylthiouracil-induced acute hepatic failure.
Topics: Adult; Amiodarone; Female; Humans; Hyperthyroidism; Liver Failure, Acute; Propylthiouracil; Triiodot | 2004 |