amiodarone has been researched along with Abnormalities, Autosome in 3 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiodarone treatment caused a significant increase in the percentage of chromosomal aberrations, decreased the mitotic index and increased DNA damage." | 1.39 | Ameliorative effect of grapefruit juice on amiodarone-induced cytogenetic and testicular damage in albino rats. ( El-Shafey, SS; Sakr, SA; Zoil, Mel-S, 2013) |
| "In amiodarone-treated groups, the most frequent chromosomal aberration was chromatid breaks." | 1.35 | Genotoxic studies in hypertensive and normotensive rats treated with amiodarone. ( Almeida, MR; Antunes, LM; Campos, MG; da Silva, VJ; de Oliveira Lima, E; Dias, FL; Salman, AK, 2008) |
| "Fetal cardiac arrhythmias are usually first suspected on the basis of auscultatory findings during routine examination in pregnancy." | 1.27 | Treatment of fetal cardiac arrhythmias. ( Stewart, PA; Wladimiroff, JW, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sakr, SA | 1 |
| Zoil, Mel-S | 1 |
| El-Shafey, SS | 1 |
| Almeida, MR | 1 |
| de Oliveira Lima, E | 1 |
| da Silva, VJ | 1 |
| Campos, MG | 1 |
| Antunes, LM | 1 |
| Salman, AK | 1 |
| Dias, FL | 1 |
| Wladimiroff, JW | 1 |
| Stewart, PA | 1 |
3 other studies available for amiodarone and Abnormalities, Autosome
| Article | Year |
|---|---|
Ameliorative effect of grapefruit juice on amiodarone-induced cytogenetic and testicular damage in albino rats.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antioxidants; Chromosome Aberrations; Citrus paradisi; | 2013 |
Genotoxic studies in hypertensive and normotensive rats treated with amiodarone.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Blood Pressure; Bone Marrow Cells; Chromosome Aberratio | 2008 |
Treatment of fetal cardiac arrhythmias.
Topics: Amiodarone; Arrhythmia, Sinus; Arrhythmias, Cardiac; Chromosome Aberrations; Chromosome Disorders; D | 1985 |