Page last updated: 2024-11-02

aminosalicylic acid and Tuberculosis, Drug-Resistant

aminosalicylic acid has been researched along with Tuberculosis, Drug-Resistant in 56 studies

Aminosalicylic Acid: An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.
4-aminosalicylic acid : An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4.

Research Excerpts

ExcerptRelevanceReference
"Rifampin (RIF) mono-resistant tuberculosis (RMR-TB) is a rare disease."7.85Treatment outcomes of rifampin-sparing treatment in patients with pulmonary tuberculosis with rifampin-mono-resistance or rifampin adverse events: A retrospective cohort analysis. ( Jo, KW; Kim, WS; Lee, SD; Park, S; Shim, TS, 2017)
"Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism were reported."7.71[Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism]. ( Horiba, M; Kimura, T; Mizutani, H; Shindoh, J; Son, M; Wakahara, K, 2001)
" A PAS population pharmacokinetic model in two dosing regimens was developed; potential covariates affecting its pharmacokinetics were examined, and Monte Carlo simulations were conducted evaluating the pharmacokinetic-pharmacodynamic index."6.79Pharmacokinetics of para-aminosalicylic acid in HIV-uninfected and HIV-coinfected tuberculosis patients receiving antiretroviral therapy, managed for multidrug-resistant and extensively drug-resistant tuberculosis. ( de Kock, L; Derendorf, H; Diacon, AH; Donald, PR; Hernandez, KR; Prescott, K; Rosenkranz, B; Sy, SK; Yu, M, 2014)
"Rifampin (RIF) mono-resistant tuberculosis (RMR-TB) is a rare disease."3.85Treatment outcomes of rifampin-sparing treatment in patients with pulmonary tuberculosis with rifampin-mono-resistance or rifampin adverse events: A retrospective cohort analysis. ( Jo, KW; Kim, WS; Lee, SD; Park, S; Shim, TS, 2017)
" Hypothyroidism is a common AE associated with ethionamide, p-aminosalicylic acid (PAS), and stavudine."3.79High rate of hypothyroidism in multidrug-resistant tuberculosis patients co-infected with HIV in Mumbai, India. ( Andries, A; Dalal, A; Das, M; Desai, C; Fernandes, D; Isaakidis, P; Khan, S; Mansoor, H; Migliori, GB; Paryani, R; Saranchuk, P; Sotgiu, G; Verma, R, 2013)
"Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism were reported."3.71[Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism]. ( Horiba, M; Kimura, T; Mizutani, H; Shindoh, J; Son, M; Wakahara, K, 2001)
" A PAS population pharmacokinetic model in two dosing regimens was developed; potential covariates affecting its pharmacokinetics were examined, and Monte Carlo simulations were conducted evaluating the pharmacokinetic-pharmacodynamic index."2.79Pharmacokinetics of para-aminosalicylic acid in HIV-uninfected and HIV-coinfected tuberculosis patients receiving antiretroviral therapy, managed for multidrug-resistant and extensively drug-resistant tuberculosis. ( de Kock, L; Derendorf, H; Diacon, AH; Donald, PR; Hernandez, KR; Prescott, K; Rosenkranz, B; Sy, SK; Yu, M, 2014)
"After the completion of the treatment course, the negative sputum conversion rate in V+D+M treatment protocol group was 84%, significantly higher than that in the control group (42%); the former group showed a focal absorption rate and pulmonary cavity closure rate of 83% and 66%, which were 33% and 26% respectively in the latter."2.71[Short-term effect of treatment protocol utilizing levofloxacin, pasiniazide and M. Vaccae on multi- drug resistant pulmonary tuberculosis]. ( Li, SM; Xing, BC; Zheng, XM, 2004)
" These drugs are associated with numerous adverse events that can cause severe morbidity, such as deafness, and in some instances can lead to death."2.66Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis. ( Ahmad, N; Baghaei, P; Barkane, L; Benedetti, A; Brode, SK; Brust, JCM; Campbell, JR; Chang, VWL; Falzon, D; Guglielmetti, L; Isaakidis, P; Kempker, RR; Kipiani, M; Kuksa, L; Lan, Z; Lange, C; Laniado-Laborín, R; Menzies, D; Nahid, P; Rodrigues, D; Singla, R; Udwadia, ZF, 2020)
" The current PASER dosing regimen is based on recommendations derived from older studies using a variety of different PAS formulations and relegate PAS to a role as an exclusively bacteriostatic agent."2.66The pharmacokinetics of para-aminosalicylic acid and its relationship to efficacy and intolerance. ( Abulfathi, AA; Adams, K; Diacon, AH; Donald, PR; Reuter, H; Svensson, EM, 2020)
" It is important to generate pharmacokinetic studies of drugs used to treat MDR TB in children in different settings, which would provide useful information on the adequacy of drug doses."2.61Pharmacokinetics of Second-Line Anti-Tubercular Drugs. ( Ramachandran, G, 2019)
"Ethionamide and PAS were the most frequently reported drugs that associated with the occurrence of hypothyroidism."2.61Is hypothyroidism rare in multidrug resistance tuberculosis patients on treatment? A systematic review and meta-analysis. ( Holakouie-Naieni, K; Lejisa, T; Mansournia, MA; Mola, M; Tesfaye, E; Tola, HH; Yaseri, M, 2019)
" para-Aminosalicylic acid (PAS), an important second-line agent for treating drug-resistant Mycobacterium tuberculosis, has moderate bioavailability and rapid clearance that necessitate high daily doses of up to 12 g per day, which in turn causes severe gastrointestinal disturbances presumably by disruption of gut microbiota and host epithelial cells."1.72Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS). ( Aldrich, CC; Baughn, AD; Boshoff, HIM; Dartois, V; Hegde, PV; Howe, MD; Jia, Z; Pan, Y; Remache, B; Sharma, S; Zimmerman, MD, 2022)
" A population pharmacokinetic model was developed describing PAS pharmacokinetics in children receiving routine RR-TB treatment."1.72Pharmacokinetics and Dose Optimization Strategies of Para-Aminosalicylic Acid in Children with Rifampicin-Resistant Tuberculosis. ( Chirehwa, M; Denti, P; Donald, PR; Draper, HR; Garcia-Prats, AJ; Hesseling, AC; Mao, J; McIlleron, H; Norman, J; Schaaf, HS; van der Laan, LE; Wiesner, L; Winckler, JL, 2022)
"The final optimized model included the addition of variability in bioavailability and allometric scaling with body weight on disposition parameters."1.56Probability of mycobactericidal activity of para-aminosalicylic acid with novel dosing regimens. ( Abulfathi, AA; Assawasuwannakit, P; Diacon, AH; Donald, PR; Reuter, H; Svensson, EM, 2020)
" Four grams of GSR-PAS twice daily but not 8 g once daily ensured concentrations exceeding the MIC (1 mg/liter) throughout the dosing interval; PAS intolerance was not related to maximum PAS concentrations over the doses studied and was not more frequent after once-daily dosing."1.42N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in patients with drug-resistant pulmonary tuberculosis. ( de Kock, L; Diacon, AH; Donald, PR; Rosenkranz, B; Sy, SK; van der Merwe, L; Werely, CJ; Xia, H, 2015)
" The present paper draws on these recent studies, synthesizes pharmacokinetic results from different population groups, and draws comparisons with in vitro data and the results of earlier pharmacokinetic studies in order to discuss the most appropriate dosing regimen for PAS-GR."1.40Dose regimen of para-aminosalicylic acid gastro-resistant formulation (PAS-GR) in multidrug-resistant tuberculosis. ( Brochart, H; Diacon, AH; Donald, PR; Kibleur, Y; Schaaf, HS, 2014)
" This case study presents the development of a granular dosing spoon pediatric delivery system for para-aminosalicylic acid."1.39Novel pediatric delivery systems for second-line anti-tuberculosis medications: a case study. ( Becerra, MC; Brigden, G; Furin, J; Lessem, E, 2013)
"MDR-TB can be successfully treated during pregnancy by using a regimen including effective second-line anti-tuberculosis drugs."1.33[Treatment outcome of patients with multidrug-resistant pulmonary tuberculosis during pregnancy]. ( Ano, H; Danno, K; Han, Y; Kawahara, K; Matsumoto, T; Nagai, T; Takashima, T; Tamura, Y; Tsuyuguchi, I; Yoshida, H, 2006)
"The study objective was to determine the minimum frequency of dosing for standard 4-g doses of p-aminosalicylic acid (PAS) granules."1.30Once-daily and twice-daily dosing of p-aminosalicylic acid granules. ( Berning, SE; Childs, JM; Huitt, GA; James, GT; Peloquin, CA; Singleton, MD, 1999)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19905 (8.93)18.7374
1990's5 (8.93)18.2507
2000's12 (21.43)29.6817
2010's23 (41.07)24.3611
2020's11 (19.64)2.80

Authors

AuthorsStudies
Krátký, M3
Vinšová, J4
Buchta, V1
Horvati, K2
Bösze, S3
Stolaříková, J4
Vavříková, E1
Polanc, S1
Kočevar, M1
Vávrová, K1
Baranyai, Z1
Szabó, I1
Paraskevopoulos, G2
Monteiro, S1
Vosátka, R1
Navrátilová, L1
Trejtnar, F1
Hegde, PV1
Howe, MD1
Zimmerman, MD1
Boshoff, HIM1
Sharma, S1
Remache, B1
Jia, Z1
Pan, Y1
Baughn, AD2
Dartois, V1
Aldrich, CC1
Wu, X1
Tan, G1
Sha, W1
Liu, H1
Yang, J1
Guo, Y1
Shen, X1
Wu, Z1
Shen, H1
Yu, F1
van der Laan, LE1
Garcia-Prats, AJ1
Schaaf, HS2
Chirehwa, M1
Winckler, JL1
Mao, J1
Draper, HR1
Wiesner, L1
Norman, J1
McIlleron, H1
Donald, PR6
Hesseling, AC1
Denti, P1
Li, Z1
Liu, F1
Chen, H1
Han, Y2
You, Y1
Xie, Y1
Zhao, Y1
Tan, J1
Guo, X1
Cheng, Y1
Wang, Y2
Li, J1
Cheng, M1
Xia, S1
Niu, X1
Wei, L1
Wang, W2
Li, S1
Ge, Q1
Guo, H1
Shang, Y1
Ren, W1
Xue, Z1
Lu, J1
Pang, Y1
Pietersen, E1
Anderson, K1
Cox, H1
Dheda, K1
Bian, A1
Shepherd, BE1
Sterling, TR1
Warren, RM1
van der Heijden, YF1
Dokladda, K1
Billamas, P1
Jaitrong, S1
Suwanakitti, N1
Phornsiricharoenphant, W1
Viratyosin, W1
Prammananan, T1
Lan, Z1
Ahmad, N1
Baghaei, P1
Barkane, L1
Benedetti, A1
Brode, SK1
Brust, JCM1
Campbell, JR1
Chang, VWL1
Falzon, D1
Guglielmetti, L1
Isaakidis, P2
Kempker, RR1
Kipiani, M1
Kuksa, L1
Lange, C1
Laniado-Laborín, R1
Nahid, P1
Rodrigues, D1
Singla, R1
Udwadia, ZF1
Menzies, D1
Abulfathi, AA2
Adams, K1
Svensson, EM2
Diacon, AH5
Reuter, H2
Assawasuwannakit, P1
Jain, AK1
Sharma, P1
Caminero, JA1
Piubello, A1
Scardigli, A1
Migliori, GB2
Park, S2
Jo, KW1
Lee, SD1
Kim, WS1
Shim, TS1
Fan, YM1
Ding, SP1
Bao, ZJ1
Wu, LM1
Zhen, LB1
Xia, Q1
Zhu, M1
Ramachandran, G1
Tola, HH1
Holakouie-Naieni, K1
Lejisa, T1
Mansournia, MA1
Yaseri, M1
Tesfaye, E1
Mola, M1
Mpagama, SG1
Heysell, SK1
Ndusilo, ND1
Kumburu, HH1
Lekule, IA1
Kisonga, RM1
Gratz, J1
Boeree, MJ1
Houpt, ER1
Kibiki, GS1
Furin, J1
Brigden, G1
Lessem, E1
Becerra, MC1
Andries, A1
Das, M1
Khan, S1
Paryani, R1
Desai, C1
Dalal, A1
Mansoor, H1
Verma, R1
Fernandes, D1
Sotgiu, G1
Saranchuk, P1
Kibleur, Y1
Brochart, H1
de Kock, L2
Sy, SK2
Rosenkranz, B2
Prescott, K1
Hernandez, KR1
Yu, M1
Derendorf, H1
Werely, CJ1
Xia, H1
van der Merwe, L1
Minato, Y1
Thiede, JM1
Kordus, SL1
McKlveen, EJ1
Turman, BJ1
Nguyen, L1
Zhao, W1
Zheng, M1
Wang, B1
Mu, X1
Li, P1
Fu, L1
Liu, S1
Guo, Z1
McNaughton, A1
Blackmore, T1
McNaughton, H1
Lai, CC1
Tan, CK1
Huang, YT1
Liao, CH1
Hsueh, PR1
Vesenbeckh, SM1
Becker, J1
Huhnt, C1
Karras, B1
Bauer, TT1
Mauch, H1
Rüssmann, H1
Schönfeld, N1
Yano, S1
Kobayashi, K1
Ikeda, T1
Kim, JH1
Jang, SH1
Kim, DH1
Kim, DG1
Jung, KS1
Wilson, JW1
Kelkar, P1
Frigas, E1
BRUN, J1
VIALLIER, J1
DUMONT, R1
SHIGEMATSU, T1
CORPE, RF1
BLALOCK, FA1
GROSS, JH1
GOLDHAMMER, EJ1
SCHLESS, JM1
ALLISON, RF1
INGLIS, RM1
WHITE, EF1
TOPPERMAN, S1
Novozhylova, IO1
Park, SK1
Lee, WC1
Lee, DH1
Mitnick, CD1
Han, L1
Seung, KJ1
Zheng, XM1
Li, SM1
Xing, BC1
Rengarajan, J1
Sassetti, CM1
Naroditskaya, V1
Sloutsky, A1
Bloom, BR1
Rubin, EJ1
Takashima, T1
Danno, K1
Tamura, Y1
Nagai, T1
Matsumoto, T1
Ano, H1
Yoshida, H1
Kawahara, K1
Tsuyuguchi, I1
Steiner, M1
Cosio, A1
Dhingra, VK1
Rajpal, S1
Mittal, A1
Hanif, M1
Kruijshaar, ME1
Watson, JM1
Drobniewski, F1
Anderson, C1
Brown, TJ1
Magee, JG1
Smith, EG1
Story, A1
Abubakar, I1
Ruggiero, SL1
Hilton, E1
Braun, TW1
Aoyagi, T1
Soumakis, SA1
Berg, D1
Harris, HW1
Peloquin, CA2
Berning, SE1
Huitt, GA1
Childs, JM1
Singleton, MD1
James, GT1
Ye, Z1
Pei, X1
Yang, Y1
Fodor, T1
Pataki, G1
Schrettner, M1
Mizutani, H1
Horiba, M1
Shindoh, J1
Kimura, T1
Son, M1
Wakahara, K1
Reid, J1
Marciniuk, D1
Hoeppner, V1
Petryszyn, K1
LeLacheur, S1

Reviews

7 reviews available for aminosalicylic acid and Tuberculosis, Drug-Resistant

ArticleYear
Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis.
    The Lancet. Respiratory medicine, 2020, Volume: 8, Issue:4

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Canada; Clofazimine; Diarylquinolines; Drug-Relat

2020
The pharmacokinetics of para-aminosalicylic acid and its relationship to efficacy and intolerance.
    British journal of clinical pharmacology, 2020, Volume: 86, Issue:11

    Topics: Aminosalicylic Acid; Antitubercular Agents; Delayed-Action Preparations; Humans; Microbial Sensitivi

2020
Pharmacokinetics of Second-Line Anti-Tubercular Drugs.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:8

    Topics: Aminoglycosides; Aminosalicylic Acid; Antitubercular Agents; Child; Cycloserine; Ethionamide; Fluoro

2019
Is hypothyroidism rare in multidrug resistance tuberculosis patients on treatment? A systematic review and meta-analysis.
    PloS one, 2019, Volume: 14, Issue:6

    Topics: Aminosalicylic Acid; Antitubercular Agents; Cross-Sectional Studies; Drug-Related Side Effects and A

2019
Mycobacterium tuberculosis folate metabolism and the mechanistic basis for para-aminosalicylic acid susceptibility and resistance.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:9

    Topics: Aminosalicylic Acid; Antitubercular Agents; Folic Acid; Microbial Sensitivity Tests; Mycobacterium t

2015
Antibiotic resistance mechanisms in M. tuberculosis: an update.
    Archives of toxicology, 2016, Volume: 90, Issue:7

    Topics: Aminosalicylic Acid; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Multiple,

2016
[Chemotherapy for tuberculosis; yesterday, today, and tomorrow--basic and clinical studies].
    Kekkaku : [Tuberculosis], 1998, Volume: 73, Issue:7

    Topics: Aminosalicylic Acid; Antitubercular Agents; Controlled Clinical Trials as Topic; Drug Delivery Syste

1998

Trials

3 trials available for aminosalicylic acid and Tuberculosis, Drug-Resistant

ArticleYear
Pharmacokinetics of para-aminosalicylic acid in HIV-uninfected and HIV-coinfected tuberculosis patients receiving antiretroviral therapy, managed for multidrug-resistant and extensively drug-resistant tuberculosis.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10

    Topics: Adult; Alkynes; Aminosalicylic Acid; Anti-Retroviral Agents; Antitubercular Agents; Benzoxazines; Cr

2014
[Short-term effect of treatment protocol utilizing levofloxacin, pasiniazide and M. Vaccae on multi- drug resistant pulmonary tuberculosis].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2004, Volume: 24, Issue:5

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aminosalicylic Acid; Aminosalicylic Acids; Clinical

2004
[Analysis of causes of drug resistance and therapeutic effects on 27 multi-drug resistant pulmonary tuberculosis patients].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1997, Volume: 20, Issue:4

    Topics: Adult; Aminosalicylic Acid; Anti-Infective Agents; Antitubercular Agents; Drug Resistance, Multiple;

1997

Other Studies

46 other studies available for aminosalicylic acid and Tuberculosis, Drug-Resistant

ArticleYear
New amino acid esters of salicylanilides active against MDR-TB and other microbes.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:12

    Topics: Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Dose-Response Relationship, Drug; D

2010
New fluorine-containing hydrazones active against MDR-tuberculosis.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Animals; Antitubercular Agents; Cell Line; Fluorine; Humans; Hydrazones; Microbial Sensitivity Tests

2011
Synthesis and in vitro biological evaluation of 2-(phenylcarbamoyl)phenyl 4-substituted benzoates.
    Bioorganic & medicinal chemistry, 2015, Feb-15, Volume: 23, Issue:4

    Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Bacterial Infections; Benzoates; Fungi; Humans;

2015
Novel salicylanilides from 4,5-dihalogenated salicylic acids: Synthesis, antimicrobial activity and cytotoxicity.
    Bioorganic & medicinal chemistry, 2017, 02-15, Volume: 25, Issue:4

    Topics: Antitubercular Agents; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Microb

2017
Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS).
    European journal of medicinal chemistry, 2022, Mar-15, Volume: 232

    Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Biological Availability; Mice; Prodrugs; Tuberc

2022
Use of Whole-Genome Sequencing to Predict
    Microbiology spectrum, 2022, 04-27, Volume: 10, Issue:2

    Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Drug Resistance; Ethambuto

2022
Pharmacokinetics and Dose Optimization Strategies of Para-Aminosalicylic Acid in Children with Rifampicin-Resistant Tuberculosis.
    Antimicrobial agents and chemotherapy, 2022, 06-21, Volume: 66, Issue:6

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Child; Drug Administration Schedule; HIV Infectio

2022
A five-year review of prevalence and treatment outcomes of pre-extensively drug-resistant plus additional drug-resistant tuberculosis in the Henan Provincial Tuberculosis Clinical Medicine Research Centre.
    Journal of global antimicrobial resistance, 2022, Volume: 31

    Topics: Aminosalicylic Acid; Antitubercular Agents; Clinical Medicine; COVID-19; Extensively Drug-Resistant

2022
Determination of critical concentration for drug susceptibility testing of Mycobacterium tuberculosis against para-aminosalicylic acid with clinical isolates with thyA, folC and dfrA mutations.
    Annals of clinical microbiology and antimicrobials, 2022, Nov-05, Volume: 21, Issue:1

    Topics: Aminosalicylic Acid; Antitubercular Agents; Drug Resistance, Bacterial; Humans; Microbial Sensitivit

2022
Variation in missed doses and reasons for discontinuation of anti-tuberculosis drugs during hospital treatment for drug-resistant tuberculosis in South Africa.
    PloS one, 2023, Volume: 18, Issue:2

    Topics: Adult; Amikacin; Aminosalicylic Acid; Antitubercular Agents; Ethionamide; Female; HIV Infections; Ho

2023
Whole genome sequencing reveals candidate genes involving in PAS resistance in M. Tuberculosis isolated from patients in Thailand.
    World journal of microbiology & biotechnology, 2023, Dec-07, Volume: 40, Issue:1

    Topics: Aminosalicylic Acid; Antitubercular Agents; DNA, Intergenic; Drug Resistance, Bacterial; Folic Acid;

2023
Probability of mycobactericidal activity of para-aminosalicylic acid with novel dosing regimens.
    European journal of clinical pharmacology, 2020, Volume: 76, Issue:11

    Topics: Aminosalicylic Acid; Antitubercular Agents; Drug Administration Schedule; Humans; Microbial Sensitiv

2020
Ethionamide induced blue vision (cyanopsia): Case report.
    The Indian journal of tuberculosis, 2020, Volume: 67, Issue:3

    Topics: Aminosalicylic Acid; Antitubercular Agents; Color Vision Defects; Cycloserine; Ethionamide; Female;

2020
Proposal for a standardised treatment regimen to manage pre- and extensively drug-resistant tuberculosis cases.
    The European respiratory journal, 2017, Volume: 50, Issue:1

    Topics: Aminosalicylic Acid; Antitubercular Agents; Carbapenems; Clofazimine; Communicable Disease Control;

2017
Treatment outcomes of rifampin-sparing treatment in patients with pulmonary tuberculosis with rifampin-mono-resistance or rifampin adverse events: A retrospective cohort analysis.
    Respiratory medicine, 2017, Volume: 131

    Topics: Adult; Age Distribution; Aged; Alcohol Drinking; Aminosalicylic Acid; Antitubercular Agents; Cohort

2017
Prognostic factors for treatment success in patients with multidrug-resistant tuberculosis in China.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 03-01, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aged; Aminosalicylic Acid; Antitubercular Agents; Child; China; Cycloserine; Drug

2018
Diagnosis and interim treatment outcomes from the first cohort of multidrug-resistant tuberculosis patients in Tanzania.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adult; Aminoglycosides; Aminosalicylic Acid; Antitubercular Agents; Comorbidity; Drug Resistance, Mu

2013
Novel pediatric delivery systems for second-line anti-tuberculosis medications: a case study.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2013, Volume: 17, Issue:9

    Topics: Administration, Oral; Age Factors; Aminosalicylic Acid; Antitubercular Agents; Chemistry, Pharmaceut

2013
High rate of hypothyroidism in multidrug-resistant tuberculosis patients co-infected with HIV in Mumbai, India.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adult; Aminosalicylic Acid; Cohort Studies; Coinfection; Ethionamide; Female; HIV Infections; Humans

2013
Dose regimen of para-aminosalicylic acid gastro-resistant formulation (PAS-GR) in multidrug-resistant tuberculosis.
    Clinical drug investigation, 2014, Volume: 34, Issue:4

    Topics: Adolescent; Adult; Aminosalicylic Acid; Chemistry, Pharmaceutical; Child; Child, Preschool; Clinical

2014
N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in patients with drug-resistant pulmonary tuberculosis.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:7

    Topics: Acetyltransferases; Adolescent; Adult; Alleles; Aminosalicylic Acid; Antitubercular Agents; Arylamin

2015
Interactions of linezolid and second-line anti-tuberculosis agents against multidrug-resistant Mycobacterium tuberculosis in vitro and in vivo.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2016, Volume: 52

    Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Capreomycin; Drug Combinations; Drug Interactio

2016
Comprehensive cost of treating one patient with MDR/pre-XDR-TB in Wellington, New Zealand.
    The European respiratory journal, 2016, Volume: 48, Issue:4

    Topics: Adult; Amikacin; Aminosalicylic Acid; Anti-Bacterial Agents; Antitubercular Agents; Bronchoscopy; Cl

2016
Fluoroquinolone-resistant tuberculosis at a medical centre in Taiwan, 2005-10.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Antitubercular Agents; Drug Resistance, Bacteri

2011
Successful oral desensitization to i.v. para-aminosalicylic acid (PAS) using encapsulated PAS dry substance.
    Infection, 2012, Volume: 40, Issue:2

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Capsules; Desensitization, Immunologic; Dose-Resp

2012
Multidrug-resistant tuberculosis that required 2 years for diagnosis.
    BMJ case reports, 2012, Mar-27, Volume: 2012

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Diagnosis, Differential; Humans; Male; Ofloxacin;

2012
A case of DRESS syndrome induced by the antituberculosis drugs, prothionamide, and para-aminosalycilic acid.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2013, Volume: 110, Issue:2

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Drug Eruptions; Eosinophilia; Humans; Male; Proth

2013
Para-aminosalicylic acid (PAS) desensitization review in a case of multidrug-resistant pulmonary tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2003, Volume: 7, Issue:5

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Desensitization, Immunologic; Female; Humans; Tub

2003
[Evolution of streptomycin-resistant tuberculosis].
    Lyon medical, 1952, Aug-03, Volume: 187, Issue:31

    Topics: Aminosalicylic Acid; Biological Evolution; Streptomycin; Tuberculosis; Tuberculosis, Multidrug-Resis

1952
[THE PROBLEM OF INFECTION WITH DRUG-RESISTANT MICROORGANISMS-TUBERCULOSIS].
    [Sogo rinsho] Clinic all-round, 1963, Volume: 12

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Drug Resistance; Drug Resistance, Microbial; Isoniazid; J

1963
RE-TREATMENT OF DRUG-RESISTANT PULMONARY TUBERCULOSIS AT BATTEY STATE HOSPITAL.
    The American review of respiratory disease, 1964, Volume: 90

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Drug Resistance; Drug Resistance, Microbial;

1964
THE USE OF ETHIONAMIDE IN COMBINED DRUG REGIMENS IN THE RE-TREATMENT OF ISONIAZID-RESISTANT PULMONARY TUBERCULOSIS.
    The American review of respiratory disease, 1965, Volume: 91

    Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Resi

1965
[M. tuberculosis drug resistance and occurrence in patients with pulmonary tuberculosis].
    Likars'ka sprava, 2003, Issue:8

    Topics: Aminosalicylic Acid; Antitubercular Agents; Drug Resistance, Bacterial; Humans; Incidence; Kanamycin

2003
Self-administered, standardized regimens for multidrug-resistant tuberculosis in South Korea.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2004, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Antitubercular Agents; Cohort Studi

2004
The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria.
    Molecular microbiology, 2004, Volume: 53, Issue:1

    Topics: Aminosalicylic Acid; Drug Resistance, Bacterial; Drug Resistance, Multiple; Folic Acid; Folic Acid A

2004
[Treatment outcome of patients with multidrug-resistant pulmonary tuberculosis during pregnancy].
    Kekkaku : [Tuberculosis], 2006, Volume: 81, Issue:6

    Topics: Adult; Aminosalicylic Acid; Amoxicillin-Potassium Clavulanate Combination; Antitubercular Agents; Cy

2006
Primary tuberculosis in children. 1. Incidence of primary drug-resistant disease in 332 children observed between the years 1961 and 1964 at the Kings County Medical Center of Brooklyn.
    The New England journal of medicine, 1966, Apr-07, Volume: 274, Issue:14

    Topics: Aminosalicylic Acid; Antitubercular Agents; Child; Child, Preschool; Drug Resistance, Bacterial; Fem

1966
Outcome of multi-drug resistant tuberculosis cases treated by individualized regimens at a tertiary level clinic.
    The Indian journal of tuberculosis, 2008, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Aminoglycosides; Aminosalicylic Acid; Antitubercular Agents; Child; Cycloserine;

2008
Increasing antituberculosis drug resistance in the United Kingdom: analysis of National Surveillance Data.
    BMJ (Clinical research ed.), 2008, May-31, Volume: 336, Issue:7655

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Disease Susceptibility; Epidemiologic Methods; Et

2008
Trismus and preauricular swelling in a 20-year-old black woman.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1996, Volume: 54, Issue:10

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Capreomycin; Diagnosis, Differential; Edema; Etha

1996
Hypothyroidism in a patient receiving treatment for multidrug-resistant tuberculosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:4

    Topics: Aminosalicylic Acid; Antitubercular Agents; Humans; Hypothyroidism; Male; Middle Aged; Tuberculosis,

1998
Once-daily and twice-daily dosing of p-aminosalicylic acid granules.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Antitubercular Agents; Chromatograp

1999
PAS infusion in treatment of multidrug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2000, Volume: 4, Issue:2

    Topics: Aminosalicylic Acid; Antitubercular Agents; Drug Therapy, Combination; Evaluation Studies as Topic;

2000
[Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism].
    Kekkaku : [Tuberculosis], 2001, Volume: 76, Issue:10

    Topics: Adult; Aged; Aminosalicylic Acid; Antitubercular Agents; Drug Therapy, Combination; Female; Humans;

2001
Pharmacokinetics of antituberculosis medications delivered via percutaneous gastrojejunostomy tube.
    Chest, 2002, Volume: 121, Issue:1

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Female; Gastrostomy; Humans; Jejunostomy; Levoflo

2002
MDR-TB: a challenge for the 21st century.
    JAAPA : official journal of the American Academy of Physician Assistants, 2002, Volume: 15, Issue:4

    Topics: Aminosalicylic Acid; Drug Resistance, Bacterial; Drug Therapy, Combination; Forecasting; Humans; Iso

2002