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aminosalicylic acid and Extensively Drug-Resistant Tuberculosis

aminosalicylic acid has been researched along with Extensively Drug-Resistant Tuberculosis in 13 studies

Aminosalicylic Acid: An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.
4-aminosalicylic acid : An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4.

Extensively Drug-Resistant Tuberculosis: Tuberculosis resistant to ISONIAZID and RIFAMPIN and at least three of the six main classes of second-line drugs (AMINOGLYCOSIDES; polypeptide agents; FLUOROQUINOLONES; THIOAMIDES; CYCLOSERINE; and PARA-AMINOSALICYLIC ACID) as defined by the CDC.

Research Excerpts

ExcerptRelevanceReference
" A PAS population pharmacokinetic model in two dosing regimens was developed; potential covariates affecting its pharmacokinetics were examined, and Monte Carlo simulations were conducted evaluating the pharmacokinetic-pharmacodynamic index."6.79Pharmacokinetics of para-aminosalicylic acid in HIV-uninfected and HIV-coinfected tuberculosis patients receiving antiretroviral therapy, managed for multidrug-resistant and extensively drug-resistant tuberculosis. ( de Kock, L; Derendorf, H; Diacon, AH; Donald, PR; Hernandez, KR; Prescott, K; Rosenkranz, B; Sy, SK; Yu, M, 2014)
"Para-aminosalicylic acid (PAS) is again needed for the treatment of multidrug and extensively drug-resistant tuberculosis (M/XDR-TB)."3.80French Nationwide Cohort Temporary Utilization Authorization Survey of GranuPAS(®) in MDR-TB patients. ( Kibleur, Y; Veziris, N, 2014)
" A PAS population pharmacokinetic model in two dosing regimens was developed; potential covariates affecting its pharmacokinetics were examined, and Monte Carlo simulations were conducted evaluating the pharmacokinetic-pharmacodynamic index."2.79Pharmacokinetics of para-aminosalicylic acid in HIV-uninfected and HIV-coinfected tuberculosis patients receiving antiretroviral therapy, managed for multidrug-resistant and extensively drug-resistant tuberculosis. ( de Kock, L; Derendorf, H; Diacon, AH; Donald, PR; Hernandez, KR; Prescott, K; Rosenkranz, B; Sy, SK; Yu, M, 2014)
" In this Review, we assess published work regarding recommendations for PAS dosing in relation to efficacy and tolerance."2.52Para-aminosalicylic acid: the return of an old friend. ( Diacon, AH; Donald, PR, 2015)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's10 (76.92)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Krátký, M1
Vinšová, J1
Buchta, V1
Horvati, K1
Bösze, S1
Stolaříková, J1
Li, Z1
Liu, F1
Chen, H1
Han, Y1
You, Y1
Xie, Y1
Zhao, Y1
Tan, J1
Guo, X1
Cheng, Y1
Wang, Y1
Li, J1
Cheng, M1
Xia, S1
Niu, X1
Wei, L1
Wang, W1
Saroha, D1
Garg, D1
Singh, AK1
Dhamija, RK1
Caminero, JA1
Piubello, A1
Scardigli, A1
Migliori, GB1
Kuo, CY1
Wang, WH1
Huang, CH1
Chen, YH1
Lu, PL1
de Kock, L1
Sy, SK1
Rosenkranz, B1
Diacon, AH2
Prescott, K1
Hernandez, KR1
Yu, M1
Derendorf, H1
Donald, PR2
Li, N1
Liao, X1
Chen, L1
Wang, J1
Liu, M1
Zhang, H1
Kibleur, Y1
Veziris, N1
Shean, K1
Siwendu, S1
van der Walt, M1
McNaughton, A1
Blackmore, T1
McNaughton, H1
Jain, NK1
Agnihotri, SP1
Sharma, KK1
Gupta, S1
Gupta, P1
Goh, TL1
Towns, CR1
Jones, KL1
Freeman, JT1
Wong, CS1

Reviews

1 review available for aminosalicylic acid and Extensively Drug-Resistant Tuberculosis

ArticleYear
Para-aminosalicylic acid: the return of an old friend.
    The Lancet. Infectious diseases, 2015, Volume: 15, Issue:9

    Topics: Aminosalicylic Acid; Antitubercular Agents; Chemistry, Pharmaceutical; Drug Discovery; Extensively D

2015

Trials

1 trial available for aminosalicylic acid and Extensively Drug-Resistant Tuberculosis

ArticleYear
Pharmacokinetics of para-aminosalicylic acid in HIV-uninfected and HIV-coinfected tuberculosis patients receiving antiretroviral therapy, managed for multidrug-resistant and extensively drug-resistant tuberculosis.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10

    Topics: Adult; Alkynes; Aminosalicylic Acid; Anti-Retroviral Agents; Antitubercular Agents; Benzoxazines; Cr

2014

Other Studies

11 other studies available for aminosalicylic acid and Extensively Drug-Resistant Tuberculosis

ArticleYear
New amino acid esters of salicylanilides active against MDR-TB and other microbes.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:12

    Topics: Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Dose-Response Relationship, Drug; D

2010
A five-year review of prevalence and treatment outcomes of pre-extensively drug-resistant plus additional drug-resistant tuberculosis in the Henan Provincial Tuberculosis Clinical Medicine Research Centre.
    Journal of global antimicrobial resistance, 2022, Volume: 31

    Topics: Aminosalicylic Acid; Antitubercular Agents; Clinical Medicine; COVID-19; Extensively Drug-Resistant

2022
Irreversible neuropathy in extremely-drug resistant tuberculosis: An unfortunate clinical conundrum.
    The Indian journal of tuberculosis, 2020, Volume: 67, Issue:3

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Clofazimine; Cycloserine; Deprescriptions; Diaryl

2020
Proposal for a standardised treatment regimen to manage pre- and extensively drug-resistant tuberculosis cases.
    The European respiratory journal, 2017, Volume: 50, Issue:1

    Topics: Aminosalicylic Acid; Antitubercular Agents; Carbapenems; Clofazimine; Communicable Disease Control;

2017
Resistance to first- and second-line antituberculosis drugs in Southern Taiwan: Implications for empirical treatment.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:1

    Topics: Aminosalicylic Acid; Antitubercular Agents; Ethambutol; Extensively Drug-Resistant Tuberculosis; Flu

2018
Antibiotic Susceptibility Patterns of Mycobacterium tuberculosis Isolates from Guizhou Province of China Against 13 Antituberculosis Drugs.
    Microbial drug resistance (Larchmont, N.Y.), 2015, Volume: 21, Issue:3

    Topics: Aminoglycosides; Aminosalicylic Acid; Antitubercular Agents; Capreomycin; China; Drug Resistance, Mu

2015
French Nationwide Cohort Temporary Utilization Authorization Survey of GranuPAS(®) in MDR-TB patients.
    Chemotherapy, 2014, Volume: 60, Issue:3

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Female;

2014
Early culture conversion and cure for extensively drug-resistant tuberculosis is possible with appropriate treatment: lessons learnt from a case study in South Africa.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2015, Volume: 40

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Capreomycin; Drug Therapy, Combination; Extensive

2015
Comprehensive cost of treating one patient with MDR/pre-XDR-TB in Wellington, New Zealand.
    The European respiratory journal, 2016, Volume: 48, Issue:4

    Topics: Adult; Amikacin; Aminosalicylic Acid; Anti-Bacterial Agents; Antitubercular Agents; Bronchoscopy; Cl

2016
Extensively drug resistance (XDR) tb is not always fatal.
    The Indian journal of tuberculosis, 2009, Volume: 56, Issue:1

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Aza Compounds; Capreomycin; Clarithromycin; Clofa

2009
Extensively drug-resistant tuberculosis: New Zealand's first case and the challenges of management in a low-prevalence country.
    The Medical journal of Australia, 2011, Jun-06, Volume: 194, Issue:11

    Topics: Acetamides; Adult; Aminosalicylic Acid; Antitubercular Agents; Aza Compounds; Cycloserine; Emigrants

2011