aminosalicylic acid has been researched along with Colitis in 15 studies
Aminosalicylic Acid: An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.
4-aminosalicylic acid : An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-five of 47 patients with distal ulcerative colitis completed a two-week double-blind, randomized, controlled trial to determine if 4-aminosalicylic acid (4-ASA) enemas, 1 g bid or 2 g bid, were therapeutically effective compared to placebo." | 9.06 | 4-Aminosalicylic acid retention enemas in treatment of distal colitis. ( Berman, P; Eagen, K; Farthing, M; Gandolfo, J; Goldberg, M; Kaplan, M; Powers, G, 1987) |
| "4-Aminosalicylic acid seems to be a suitable drug for improving the clinical symptoms of ulcerative proctitis." | 5.28 | Experience with topical administration of 4-aminosalicylic acid in ulcerative colitis. ( Karacsony, G; Nagy, F; Varro, V, 1989) |
| " We report here synthesis, in vitro release kinetics of macromolecular prodrug of 4-aminosalicylic acid (4-ASA) with β-cyclodextrin and its extensive pharmacological evaluation in 2, 4, 6- trinitrobenzenesulphonic acid - induced colitis in rats." | 3.79 | Macromolecular prodrug of 4-aminosalicylic acid for targeted delivery to inflamed colon. ( Dhaneshwar, S; Vadnerkar, G, 2013) |
| " The prodrugs exhibited comparable ameliorating effect as that of sulfasalazine on trinitrobenzenesulfonic acid-induced experimental colitis in rats with a better safety profile." | 3.75 | Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease. ( Bhatt, L; Dhaneshwar, SS; Gairola, N; Kadam, SS; Kandpal, M; Rathi, B; Vadnerkar, G, 2009) |
| "4-Aminosalicylic acid seems to be a suitable drug for improving the clinical symptoms of ulcerative proctitis." | 1.28 | Experience with topical administration of 4-aminosalicylic acid in ulcerative colitis. ( Karacsony, G; Nagy, F; Varro, V, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Dhaneshwar, SS | 2 |
| Chail, M | 1 |
| Patil, M | 1 |
| Naqvi, S | 1 |
| Vadnerkar, G | 3 |
| Gairola, N | 1 |
| Kandpal, M | 1 |
| Bhatt, L | 1 |
| Rathi, B | 1 |
| Kadam, SS | 1 |
| Otkur, W | 1 |
| Wang, J | 1 |
| Hou, T | 1 |
| Liu, F | 1 |
| Yang, R | 1 |
| Li, Y | 1 |
| Xiang, K | 1 |
| Pei, S | 1 |
| Qi, H | 1 |
| Lin, H | 1 |
| Zhou, H | 1 |
| Zhang, X | 1 |
| Piao, HL | 1 |
| Liang, X | 1 |
| Moreira, TG | 1 |
| Horta, LS | 1 |
| Gomes-Santos, AC | 1 |
| Oliveira, RP | 1 |
| Queiroz, NMGP | 1 |
| Mangani, D | 1 |
| Daniel, B | 1 |
| Vieira, AT | 1 |
| Liu, S | 1 |
| Rodrigues, AM | 1 |
| Gomes, DA | 1 |
| Gabriely, G | 1 |
| Ferreira, E | 1 |
| Weiner, HL | 1 |
| Rezende, RM | 1 |
| Nagy, L | 1 |
| Faria, AMC | 1 |
| Ning, L | 1 |
| Lou, X | 1 |
| Zhang, F | 1 |
| Xu, G | 1 |
| Suneela, D | 2 |
| Gaurav, V | 2 |
| Himanshu, R | 1 |
| Samuel, S | 1 |
| Dhaneshwar, S | 1 |
| KON, II | 1 |
| LAMBLING, A | 1 |
| GOUGIS, M | 1 |
| BERNIER, JJ | 1 |
| Zijlstra, FJ | 1 |
| Van Dijk, JP | 1 |
| Wilson, JH | 1 |
| Simmonds, NJ | 1 |
| Millar, AD | 1 |
| Blake, DR | 1 |
| Rampton, DS | 1 |
| Rachmilewitz, D | 1 |
| Karmeli, F | 1 |
| Schwartz, LW | 1 |
| Simon, PL | 1 |
| Nagy, F | 1 |
| Karacsony, G | 1 |
| Varro, V | 1 |
| Gandolfo, J | 1 |
| Farthing, M | 1 |
| Powers, G | 1 |
| Eagen, K | 1 |
| Goldberg, M | 1 |
| Berman, P | 1 |
| Kaplan, M | 1 |
1 review available for aminosalicylic acid and Colitis
| Article | Year |
|---|---|
Nuclear Receptors in the Pathogenesis and Management of Inflammatory Bowel Disease.
Topics: Aminosalicylic Acid; Animals; Colitis; Humans; Inflammatory Bowel Diseases; PPAR gamma; Pregnane X R | 2019 |
1 trial available for aminosalicylic acid and Colitis
| Article | Year |
|---|---|
4-Aminosalicylic acid retention enemas in treatment of distal colitis.
Topics: Adult; Aged; Aminosalicylic Acid; Aminosalicylic Acids; Clinical Trials as Topic; Colitis; Double-Bl | 1987 |
13 other studies available for aminosalicylic acid and Colitis
| Article | Year |
|---|---|
Colon-specific mutual amide prodrugs of 4-aminosalicylic acid for their mitigating effect on experimental colitis in rats.
Topics: Aminosalicylic Acids; Animals; Colitis; Colon; Drug Delivery Systems; Drug Stability; Drug-Related S | 2009 |
Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease.
Topics: Aminosalicylic Acids; Animals; Arthritis; Colitis; Colon; Female; Inflammatory Bowel Diseases; Male; | 2009 |
Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Colitis; Colon; Dextran Sulfate; Disease Models, | 2023 |
CLA-supplemented diet accelerates experimental colorectal cancer by inducing TGF-β-producing macrophages and T cells.
Topics: Aminosalicylic Acid; Animals; Carcinogenesis; Cells, Cultured; Colitis; Colorectal Neoplasms; Dextra | 2019 |
Design and development of novel azo prodrugs using various permutations and combinations of 5- and 4-aminosalicylic acids for inflammatory bowel disease: a colon-targeted approach.
Topics: Aminosalicylic Acid; Animals; Azo Compounds; Colitis; Colon; Drug Design; Female; Humans; Inflammato | 2013 |
Azo reductase- activated colon- targeting prodrugs of aminosalicylates for inflammatory bowel disease: preparation, pharmacokinetic and pharmacodynamic profile.
Topics: Aminosalicylic Acid; Animals; Azo Compounds; Colitis; Colon; Drug Delivery Systems; Humans; Hydropho | 2013 |
Macromolecular prodrug of 4-aminosalicylic acid for targeted delivery to inflamed colon.
Topics: 1-Octanol; Aminosalicylic Acid; Animals; Anti-Inflammatory Agents; beta-Cyclodextrins; Colitis; Drug | 2013 |
[Comparative evaluation of tuberculous colitis treated and not treated with streptomycin and PAS].
Topics: Aminosalicylic Acid; Colitis; Streptomycin; Tuberculosis | 1956 |
[The treatment of hemorrhagic rectocolitis (ulcerative colitis) by isoniazid with or without streptomycin and PAS].
Topics: Aminosalicylic Acid; Colitis; Colitis, Ulcerative; Isoniazid; Proctocolitis; Streptomycin | 1959 |
Increased platelet activating factor synthesis in experimental colitis after diclofenac and 5-amino-salicylic acid.
Topics: Aminosalicylic Acid; Animals; Colitis; Dextrans; Diclofenac; Diterpenes; Female; Ginkgolides; Lacton | 1993 |
Antioxidant effects of aminosalicylates and potential new drugs for inflammatory bowel disease: assessment in cell-free systems and inflamed human colorectal biopsies.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aminosalicylic Acid; Aminosalicylic Acids; Anti-Infective Agen | 1999 |
Effect of aminophenols (5-ASA and 4-ASA) on colonic interleukin-1 generation.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Colitis; Colon; Disease Models, Animal; Humans; | 1992 |
Experience with topical administration of 4-aminosalicylic acid in ulcerative colitis.
Topics: Administration, Topical; Aminosalicylic Acid; Aminosalicylic Acids; Colitis; Colon; Enema; Humans; I | 1989 |