Page last updated: 2024-09-05

aminopterin and Sarcoma 180

aminopterin has been researched along with Sarcoma 180 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199010 (90.91)18.7374
1990's1 (9.09)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gaumont, Y; Kisliuk, RL; McCaleb, GS; Montgomery, JA; Piper, JR; Sirotnak, FM1
FISHER, J; GOLDBERG, B; SCHOENBACH, EB; WEISSMAN, N1
GOLDBERG, B; GOLDIN, A1
STOCK, CC; THIERSCH, JB1
Chello, PL; DeGraw, JI; Dorick, DM; Moccio, DM; Sirotnak, FM1
Chiao, JH; Roy, K; Sirotnak, FM; Tolner, B1
DeGraw, JI; Dorick, DM; Moccio, DM; Sirotnak, FM1
Donsback, RC; Sirotnak, FM1
Montgomery, JA; Otter, GM; Piper, JR; Schmid, FA; Sirotnak, FM1
Cihar, R; Hermanovã, E; Pristoupilovã, K; Slavĩk, K; Slavĩkovã, V; Soucek, J1
Hakala, MT1

Other Studies

11 other study(ies) available for aminopterin and Sarcoma 180

ArticleYear
10-Propargylaminopterin and alkyl homologues of methotrexate as inhibitors of folate metabolism.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:7

    Topics: Aminopterin; Animals; Antineoplastic Agents; Bacteria; Cells, Cultured; Folic Acid; Folic Acid Antagonists; Leukemia L1210; Membranes; Methotrexate; Mice; Neoplasms, Experimental; Sarcoma 180

1982
Nucleic acid changes in sarcoma 180 following administration of aminopterin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 80, Issue:3

    Topics: Aminopterin; Animals; Nucleic Acids; Sarcoma 180

1952
Reversal of aminopterin-induced inhibition of sarcoma 180 by folic acid.
    Cancer, 1949, Volume: 2, Issue:5

    Topics: Aminopterin; Animals; Folic Acid; Sarcoma 180; Sarcoma, Experimental

1949
Bone marrow of mice bearing sarcoma 180 treated with 4-amino-pteroylglutamic acid and with 4-amino-N10-methyl-pteroylglutaminic acid.
    Cancer, 1949, Volume: 2, Issue:5

    Topics: Aminopterin; Animals; Bone and Bones; Bone Marrow; Bone Neoplasms; Folic Acid; Mice; Neoplasms; Sarcoma 180; Sarcoma, Experimental

1949
Biochemical and pharmacologic properties of a new folate analog, 10-deaza-aminopterin, in mice.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: Aminopterin; Animals; Carcinoma, Ehrlich Tumor; Folic Acid Antagonists; Intestine, Small; Leukemia L1210; Membranes; Methotrexate; Mice; Sarcoma 180; Tetrahydrofolate Dehydrogenase

1982
A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues. Implications for intrinsic antifolate resistance and directional orientation of the transporter within
    The Journal of biological chemistry, 1998, Jan-30, Volume: 273, Issue:5

    Topics: Amino Acid Sequence; Aminopterin; Animals; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Cell Membrane; Drug Resistance, Neoplasm; Folic Acid Antagonists; Leukemia L1210; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mice; Models, Molecular; Molecular Sequence Data; Neoplasm Proteins; Protein Conformation; Sarcoma 180; Sequence Homology, Amino Acid; Tumor Cells, Cultured

1998
Antitumor properties of a new folate analog, 10-deaza-aminopterin, in mice.
    Cancer treatment reports, 1978, Volume: 62, Issue:7

    Topics: Aminopterin; Animals; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinical; Female; Folic Acid; Leukemia L1210; Liver Neoplasms; Male; Methotrexate; Mice; Neoplasms, Experimental; Plasmacytoma; Sarcoma 180

1978
Further evidence for a basis of selective activity and relative responsiveness during antifolate therapy of murine tumors.
    Cancer research, 1975, Volume: 35, Issue:7

    Topics: Aminopterin; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Chick Embryo; DNA, Neoplasm; Folic Acid Antagonists; Intestine, Small; Leukemia L1210; Liver; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Quinazolines; Sarcoma 180; Tetrahydrofolate Dehydrogenase; Time Factors

1975
Structural design, biochemical properties, and evidence for improved therapeutic activity of 5-alkyl derivatives of 5-deazaaminopterin and 5-deazamethotrexate compared to methotrexate in murine tumor models.
    Cancer research, 1988, Oct-15, Volume: 48, Issue:20

    Topics: Adenocarcinoma; Alkylation; Aminopterin; Animals; Drug Compounding; Epithelium; Intestine, Small; Kinetics; Mammary Neoplasms, Experimental; Methotrexate; Mice; Sarcoma 180; Structure-Activity Relationship

1988
Isohomoaminopterin and isohomofolic acid. Synthesis and basic biochemical and biological properties.
    Molecular pharmacology, 1972, Volume: 8, Issue:6

    Topics: Aminopterin; Animals; Chromatography, Paper; Columbidae; Esters; Folic Acid; Folic Acid Antagonists; HeLa Cells; Hydrogen-Ion Concentration; Hydrolysis; Lacticaseibacillus casei; Sarcoma 180; Spectrometry, Fluorescence; Spectrophotometry; Streptococcus; Time Factors

1972
On the role of drug penetration in amethopterin resistance of Sarcoma-180 cells in vitro.
    Biochimica et biophysica acta, 1965, May-25, Volume: 102, Issue:1

    Topics: Aminopterin; Animals; In Vitro Techniques; Methotrexate; Sarcoma 180; Tetrahydrofolate Dehydrogenase

1965