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aminopterin and Experimental Leukemia

aminopterin has been researched along with Experimental Leukemia in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199018 (94.74)18.7374
1990's1 (5.26)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ensminger, WD; Lazarus, H; Rosowsky, A; Yu, CS1
Cohn, NK; Duch, DS; Edelstein, MP; Ferone, R; Hanlon, MH; Kelley, JL; McLean, EW; Smith, GK1
GOLDIN, A; GREENHOUSE, SW; HUMPHREYS, SR; MANTEL, N; VENDITTI, JM2
DENNIS, D; GOLDIN, A; GREENHOUSE, SW; HUMPHREYS, SR; MANTEL, N; VENDITTI, JM2
DENNIS, D; GOLDIN, A; HUMPHREYS, SR; MANTEL, N; VENDITTI, JM1
CUTTS, JH1
JIRASEK, A; JIRASEK, J; MOTYCKA, K; SLAVIK, K; SOUCEK, J1
MOTYCKA, K; SLAVIK, K; SOUCEK, J1
MORSE, E; OLIVERIO, VT; RALL, DP; RIESELBACH, RE1
McCormack, JJ1
Andreeva, NA; Ershova, IuA; Nemeriuk, MP; Riabokon', NA; Sokolova, AS1
Bailey, BD; Goldman, ID; Hill, BT; White, JC1
Goldin, A1
Avery, TL; Blakley, RL; Brixner, DI; Broom, AD; Kuehl, M1
Motycka, K1
Hutchison, DJ; Schmid, FA; Shimoyama, M1
Motycka, K; Pristoupilová, K; Slavík, K; Soucek, J1

Reviews

2 review(s) available for aminopterin and Experimental Leukemia

ArticleYear
Dihydrofolate reductase inhibitors as potential drugs.
    Medicinal research reviews, 1981,Fall, Volume: 1, Issue:3

    Topics: Aminopterin; Animals; Antimalarials; Bacterial Infections; Biological Transport; Drug Interactions; Folic Acid; Folic Acid Antagonists; Helminthiasis; Humans; Immunosuppressive Agents; Leukemia, Experimental; Liver; Methotrexate; Mice; Mycoses; Neoplasms; Protozoan Infections; Psoriasis; Quinazolines; Rats; Receptors, Drug; Trypanosoma cruzi

1981
Studies with high-dose methotrexate--historical background.
    Cancer treatment reports, 1978, Volume: 62, Issue:2

    Topics: Aminopterin; Animals; Folic Acid; History, 20th Century; Humans; Leucovorin; Leukemia, Experimental; Methotrexate; Mice; Neoplasms; Time Factors

1978

Other Studies

17 other study(ies) available for aminopterin and Experimental Leukemia

ArticleYear
Methotrexate analogues. 8. Synthesis and biological evaluation of bisamide derivatives as potential prodrugs.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:7

    Topics: Amides; Animals; Antineoplastic Agents; Cells, Cultured; Chromatography, Thin Layer; Folic Acid Antagonists; Humans; Lacticaseibacillus casei; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Liver; Methotrexate; Mice; Rats

1977
Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:2

    Topics: Acyltransferases; Animals; Antimetabolites, Antineoplastic; Cell Line; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Hydroxymethyl and Formyl Transferases; Leukemia, Experimental; Mice; Peptide Synthases; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase; Purines; Structure-Activity Relationship; Tetrahydrofolates

1990
Effect of delayed administration of citrovorum factor on the antileukemic effectiveness of aminopterin in mice.
    Cancer research, 1954, Volume: 14, Issue:1

    Topics: Aminopterin; Animals; Antimetabolites; Folic Acid; Leucovorin; Leukemia, Experimental; Mice

1954
Factors influencing the specificity of action of an antileukemic agent (aminopterin); time of treatment and dosage schedule.
    Cancer research, 1954, Volume: 14, Issue:4

    Topics: Aminopterin; Animals; Antineoplastic Agents; Leukemia, Experimental; Sensitivity and Specificity

1954
Factors influencing the specificity of action of an antileukemic agent (aminopterin); multiple treatment schedules plus delayed administration of citrovorum factor.
    Cancer research, 1955, Volume: 15, Issue:1

    Topics: Aminopterin; Animals; Antineoplastic Agents; Folic Acid; Leucovorin; Leukemia, Experimental

1955
Factors influencing the specificity of action of an antileukemic agent (aminopterin): host age and weight.
    Journal of the National Cancer Institute, 1955, Volume: 16, Issue:3

    Topics: Aging; Aminopterin; Animals; Body Weight; Leukemia, Experimental; Sensitivity and Specificity

1955
EFFECTS OF OTHER AGENTS ON THE BIOLOGIC RESPONSES TO VINCALEUKOBLASTINE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: 2-Aminopurine; Aminopterin; Animals; Aspartic Acid; Azaguanine; Biological Products; Colchicine; Cortisone; Glutamates; Leukemia; Leukemia L1210; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Pharmacology; Purines; Research; Tryptophan; Vinblastine

1964
THE TREATMENT OF EXPERIMENTAL MOUSE HEMOBLASTOSIS. I. THE EFFECT OF SOME NEW FOLIC ACID ANTIMETABOLITES ON CELL TRANSPLANTED LEUKEMIA IN MICE OF THE AKR STRAIN.
    Neoplasma, 1964, Volume: 11

    Topics: Aminopterin; Animals; Antimetabolites; Antineoplastic Agents; Folic Acid; Leukemia; Leukemia, Experimental; Leukocyte Count; Methotrexate; Mice; Mice, Inbred AKR; Pharmacology; Research; Toxicology

1964
THE TREATMENT OF EXPERIMENTAL MOUSE HEMOBLASTOSIS. II. THE EFFECT OF LONG-TERM ADMINISTRATION OF SOME FOLIC ACID ANTAGONISTS ON MICE OF THE AKR STRAIN.
    Neoplasma, 1964, Volume: 11

    Topics: Aminopterin; Animals; Chemical and Drug Induced Liver Injury; Folic Acid Antagonists; Hepatitis; Leukemia; Leukemia, Experimental; Liver; Mice; Mice, Inbred AKR; Pharmacology; Research; Toxicology

1964
A quantitative comparison of the antileukemic effectiveness of two folic acid antagonists in mice.
    Journal of the National Cancer Institute, 1955, Volume: 15, Issue:6

    Topics: Aminopterin; Animals; Folic Acid Antagonists; Leukemia, Experimental; Mice

1955
Pharmacology of folic acid antagonists as related to brain and cerebrospinal fluid.
    Cancer chemotherapy reports, 1962, Volume: 16

    Topics: Aminopterin; Animals; Brain; Cerebrospinal Fluid; Folic Acid Antagonists; Humans; Leukemia, Experimental

1962
[Tomizine--a new inhibitor of folate metabolism enzymes possessing an antitumor activity].
    Voprosy onkologii, 1975, Volume: 21, Issue:11

    Topics: Aminopterin; Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Folic Acid Antagonists; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Lymphoma, Non-Hodgkin; Methotrexate; Mice; Neoplasms, Experimental; Rats; Sarcoma 37; Sarcoma, Experimental; Thiazines

1975
Characteristics of transport of 4-amino antifolates and folate compounds by two lines of L5178Y lymphoblasts, one with impaired transport of methotrexate.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: 4-Chloromercuribenzenesulfonate; Aminopterin; Animals; Azides; Biological Transport; Cell Line; Cell Membrane; Drug Resistance; Formyltetrahydrofolates; Leukemia, Experimental; Methotrexate; Mice; Tetrahydrofolates

1979
Cytotoxicity, uptake, polyglutamate formation, and antileukemic effects of 8-deaza analogues of methotrexate and aminopterin in mice.
    Cancer research, 1988, Mar-15, Volume: 48, Issue:6

    Topics: Aminopterin; Animals; Antineoplastic Agents; Cell Survival; Female; Folic Acid Antagonists; Humans; Hydroxylation; Leukemia, Experimental; Methotrexate; Mice; Mice, Inbred Strains; Peptides; Polyglutamic Acid; Rabbits; Tetrahydrofolate Dehydrogenase

1988
Studies on the effect of antifolics in mouse leukemia.
    National Cancer Institute monograph, 1971, Volume: 34

    Topics: Age Factors; Aminopterin; Animals; Antineoplastic Agents; Arylformamidase; Carcinoma, Ehrlich Tumor; Dactinomycin; Drug Resistance; Folic Acid Antagonists; Leukemia, Experimental; Liver; Methotrexate; Mice; Mitosis; Oxidoreductases; Spleen; Tetrahydrofolate Dehydrogenase; Vincristine

1971
Quinazoline antifolates: dosage schedules and toxicity.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:2

    Topics: Aminopterin; Animals; Antineoplastic Agents; Body Weight; Dosage Forms; Folic Acid Antagonists; Leucovorin; Leukemia, Experimental; Male; Methotrexate; Mice; Quinazolines

1971
The treatment of experimental mouse hemoblastosis. VI.
    Neoplasma, 1968, Volume: 15, Issue:1

    Topics: Aminopterin; Animals; Bromine; Coenzymes; Dactinomycin; Folic Acid; Leukemia, Experimental; Liver; Spleen

1968