Page last updated: 2024-09-05

aminopterin and Carcinoma, Epidermoid

aminopterin has been researched along with Carcinoma, Epidermoid in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's11 (57.89)18.2507
2000's0 (0.00)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elliott, RD; Montgomery, JA; Piper, JR; Roberts, EC; Shealy, YF; Temple, C1
Bader, H; Cucchi, CA; Forsch, RA; Frei, E; Freisheim, JH; Rosowsky, A; Susten, SS1
Apollo, A; Cox, L; Fury, MG; Haque, S; Ho, AL; Lipson, BL; Lyo, JK; Pfister, DG; Sales, R; Seetharamu, N; Sherman, EJ; Sima, CS; Xiao, H1
Azzoli, CG; Dunne, M; Ginsberg, M; Huntington, M; James, L; Kris, MG; Krug, LM; May, J; Miller, V; Patel, JD; Saunders, M; Sirotnak, FM; Subzwari, S; Tyson, L1
FREEMAN, RG; KNOX, JM; ROSSMAN, RE1
Ackerman, AB; Lantis, LR; Samitz, MH1
Braakhuis, BJ; Jansen, G; Kegel, A; Noordhuis, P; Peters, GJ1
Armand, JP; Cappelaere, P; Clavel, M; Cognetti, F; de Graeff, A; de Mulder, PH; Schornagel, JH; Vermorken, JB; Verweij, J; Wildiers, J1
Benner, SE; Dimery, IW; Esparaz, B; Frenning, D; Guillory-Perez, C; Hong, WK; Huber, MH; Lippman, SM; Shirinian, M1
Benedetti, J; Ensley, J; Grunberg, SM; Kuebler, JP; Marshall, ME; Muirhead, MJ; Richert-Boe, KE; Schuller, DE1
Braakhuis, BJ; Jansen, G; Peters, GJ1
Broun, ER; Iseminger, KA; Lentz, SL; Lincoln, S; Malfetano, JH; Mannel, R; Rose, PG1
Armand, JP; Cappelaere, P; Clavel, M; Cognetti, F; de Mulder, PH; Kirkpatrick, A; Schornagel, JH; Vermorken, JB; Verweij, J; Wildiers, J1
Green, MD; Sherman, P; Zalcberg, J1
Hordijk, GJ; Jansen, G; Kathmann, GA; Schornagel, JH; van der Laan, BF; Westerhof, GR1
Braakhuis, BJ; Brown, DH; Snow, GB; Van Dongen, GA1
Clavel, M; Cognetti, F; de Mulder, P; Henzen-Logmans, S; Schornagel, J; Vermorken, J; Verweij, J1
Banzet, P; De la Caffinière, JY; Dufourmentel, C1
Higgins, ML; Leach, FR; Leach, KK; Melnykovych, G; Tillman, MC1

Trials

9 trial(s) available for aminopterin and Carcinoma, Epidermoid

ArticleYear
A phase II study of pralatrexate with vitamin B12 and folic acid supplementation for previously treated recurrent and/or metastatic head and neck squamous cell cancer.
    Investigational new drugs, 2014, Volume: 32, Issue:3

    Topics: Adult; Aged; Aminopterin; Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck; Vitamin B 12; Vitamin B Complex; Young Adult

2014
Pralatrexate with vitamin supplementation in patients with previously treated, advanced non-small cell lung cancer: safety and efficacy in a phase 1 trial.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2011, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Tissue Distribution; Vitamin B 12; Vitamin B Complex

2011
Randomized phase III trial of edatrexate versus methotrexate in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck: a European Organization for Research and Treatment of Cancer Head and Neck Cancer Cooperative Group stu
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:7

    Topics: Agranulocytosis; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Lung; Male; Methotrexate; Respiratory Distress Syndrome; Thrombocytopenia

1995
Phase II study of carboplatin and edatrexate (10-EdAM) with leucovorin rescue for patients with recurrent squamous cell carcinoma of the head and neck.
    Investigational new drugs, 1994, Volume: 12, Issue:4

    Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local

1994
Phase II study of edatrexate in advanced head and neck cancer. A Southwest Oncology Group study.
    Investigational new drugs, 1994, Volume: 12, Issue:4

    Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local

1994
A phase II trial of edatrexate in previously treated squamous cell cervical cancer: a Gynecologic Oncology Group study.
    American journal of clinical oncology, 1997, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Fanconi Syndrome; Female; Folic Acid Antagonists; Humans; Middle Aged; Neoplasm Recurrence, Local; Uterine Cervical Neoplasms

1997
A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and/or recurrent squamous cell carcinoma of the head and neck. The EORTC Head and Neck Cancer Cooperative Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:3

    Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leukopenia; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Thrombocytopenia

1992
Phase II study of 10-EdAM in patients with squamous cell carcinoma of the head and neck, previously untreated with chemotherapy.
    Investigational new drugs, 1992, Volume: 10, Issue:1

    Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged

1992
Toxic dermatitis induced by 10-ethyl-10-deaza-aminopterin (10-EdAM), a novel antifolate.
    Cancer, 1990, Nov-01, Volume: 66, Issue:9

    Topics: Aged; Aminopterin; Carcinoma, Squamous Cell; Dermatitis, Contact; Drug Evaluation; Female; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Skin

1990

Other Studies

10 other study(ies) available for aminopterin and Carcinoma, Epidermoid

ArticleYear
Analogues of methotrexate.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Survival; Columbidae; Folic Acid Antagonists; Humans; In Vitro Techniques; Leukemia L1210; Liver; Methotrexate; Mice; Structure-Activity Relationship

1979
Methotrexate analogues. 25. Chemical and biological studies on the gamma-tert-butyl esters of methotrexate and aminopterin.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: Aminopterin; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Drug Resistance; Esterification; Folic Acid Antagonists; Humans; In Vitro Techniques; Leukemia; Leukemia L1210; Methotrexate; Mice; T-Lymphocytes

1985
MULTIPLE KERATOACANTHOMAS. A CASE STUDY OF THE ERUPTIVE TYPE WITH OBSERVATIONS ON PATHOGENESIS.
    Archives of dermatology, 1964, Volume: 89

    Topics: Aminopterin; Black People; Carcinoma; Carcinoma, Squamous Cell; Diagnosis, Differential; Foot Diseases; Hand Dermatoses; Histocytochemistry; Humans; Keratoacanthoma; Laryngeal Neoplasms; Methotrexate; Neoplasms; Pathology; Ultraviolet Rays

1964
Squamous cell carcinoma arising at the site of oral florid papillomatosis.
    Archives of dermatology, 1967, Volume: 96, Issue:3

    Topics: Aminopterin; Carcinoma, Squamous Cell; Follow-Up Studies; Iridium; Mouth Mucosa; Mouth Neoplasms; Papilloma; Radioisotopes

1967
Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Polyglutamic Acid; Tumor Cells, Cultured

1993
Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Cell Line; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tumor Cells, Cultured

1993
In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
    International journal of cancer, 1992, Jul-30, Volume: 51, Issue:6

    Topics: Aminopterin; Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tumor Cells, Cultured

1992
Comparative study of the sensitivity of head and neck cell lines to methotrexate (MTX) and the analog 10-ethyl, 10-deazaaminopterin (10-EdAM).
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1990, Volume: 102, Issue:1

    Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Line; Folic Acid Antagonists; Head and Neck Neoplasms; In Vitro Techniques; Methotrexate; Tumor Cells, Cultured

1990
[Apropos of 40 cases of malignant tumors treated by local-regional and general chemotherapy in a surgical department].
    Journal de chirurgie, 1969, Volume: 97, Issue:3

    Topics: Adolescent; Adult; Aminopterin; Back; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Facial Neoplasms; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Leg; Male; Melanoma; Middle Aged; Osteosarcoma; Sarcoma, Ewing; Vinblastine

1969
Studies on the variability of the KB cell line.
    Texas reports on biology and medicine, 1969,Winter, Volume: 27, Issue:4

    Topics: Alkaline Phosphatase; Aminopterin; Azaguanine; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Line; Chromosomes; Clone Cells; Culture Techniques; Enzyme Induction; Humans; Mercaptopurine; Mouth Neoplasms; Sulfhydryl Compounds

1969