aminopterin has been researched along with Cancer of Head in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (84.62) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Apollo, A; Cox, L; Fury, MG; Haque, S; Ho, AL; Lipson, BL; Lyo, JK; Pfister, DG; Sales, R; Seetharamu, N; Sherman, EJ; Sima, CS; Xiao, H | 1 |
| Braakhuis, BJ; Jansen, G; Kegel, A; Noordhuis, P; Peters, GJ | 1 |
| Armand, JP; Cappelaere, P; Clavel, M; Cognetti, F; de Graeff, A; de Mulder, PH; Schornagel, JH; Vermorken, JB; Verweij, J; Wildiers, J | 1 |
| Benner, SE; Dimery, IW; Esparaz, B; Frenning, D; Guillory-Perez, C; Hong, WK; Huber, MH; Lippman, SM; Shirinian, M | 1 |
| Benedetti, J; Ensley, J; Grunberg, SM; Kuebler, JP; Marshall, ME; Muirhead, MJ; Richert-Boe, KE; Schuller, DE | 1 |
| Braakhuis, BJ; Jansen, G; Peters, GJ | 1 |
| Perez, EA | 1 |
| Chronowski, G; Heelan, RT; Kris, MG; Laurie, SA; Pfister, DG; Pisters, KM; Sirotnak, FM; Tong, WP | 1 |
| Armand, JP; Cappelaere, P; Clavel, M; Cognetti, F; de Mulder, PH; Kirkpatrick, A; Schornagel, JH; Vermorken, JB; Verweij, J; Wildiers, J | 1 |
| Green, MD; Sherman, P; Zalcberg, J | 1 |
| Hordijk, GJ; Jansen, G; Kathmann, GA; Schornagel, JH; van der Laan, BF; Westerhof, GR | 1 |
| Braakhuis, BJ; Brown, DH; Snow, GB; Van Dongen, GA | 1 |
| Clavel, M; Cognetti, F; de Mulder, P; Henzen-Logmans, S; Schornagel, J; Vermorken, J; Verweij, J | 1 |
8 trial(s) available for aminopterin and Cancer of Head
| Article | Year |
|---|---|
A phase II study of pralatrexate with vitamin B12 and folic acid supplementation for previously treated recurrent and/or metastatic head and neck squamous cell cancer.
Topics: Adult; Aged; Aminopterin; Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck; Vitamin B 12; Vitamin B Complex; Young Adult | 2014 |
Randomized phase III trial of edatrexate versus methotrexate in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck: a European Organization for Research and Treatment of Cancer Head and Neck Cancer Cooperative Group stu
Topics: Agranulocytosis; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Lung; Male; Methotrexate; Respiratory Distress Syndrome; Thrombocytopenia | 1995 |
Phase II study of carboplatin and edatrexate (10-EdAM) with leucovorin rescue for patients with recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local | 1994 |
Phase II study of edatrexate in advanced head and neck cancer. A Southwest Oncology Group study.
Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local | 1994 |
Phase I and pharmacological study of two schedules of the antifolate edatrexate in combination with cisplatin.
Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dose-Response Relationship, Drug; Female; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Time Factors; Treatment Outcome | 2001 |
A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and/or recurrent squamous cell carcinoma of the head and neck. The EORTC Head and Neck Cancer Cooperative Group.
Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leukopenia; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Thrombocytopenia | 1992 |
Phase II study of 10-EdAM in patients with squamous cell carcinoma of the head and neck, previously untreated with chemotherapy.
Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged | 1992 |
Toxic dermatitis induced by 10-ethyl-10-deaza-aminopterin (10-EdAM), a novel antifolate.
Topics: Aged; Aminopterin; Carcinoma, Squamous Cell; Dermatitis, Contact; Drug Evaluation; Female; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Skin | 1990 |
5 other study(ies) available for aminopterin and Cancer of Head
| Article | Year |
|---|---|
Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Polyglutamic Acid; Tumor Cells, Cultured | 1993 |
Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck.
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Division; Cell Line; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tumor Cells, Cultured | 1993 |
Schedule-dependent edatrexate toxicity.
Topics: Aminopterin; Antineoplastic Agents; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Mouth Mucosa; Palliative Care; Stomatitis | 1996 |
In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
Topics: Aminopterin; Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tumor Cells, Cultured | 1992 |
Comparative study of the sensitivity of head and neck cell lines to methotrexate (MTX) and the analog 10-ethyl, 10-deazaaminopterin (10-EdAM).
Topics: Aminopterin; Carcinoma, Squamous Cell; Cell Line; Folic Acid Antagonists; Head and Neck Neoplasms; In Vitro Techniques; Methotrexate; Tumor Cells, Cultured | 1990 |