Page last updated: 2024-09-05

aminopterin and Breast Neoplasms

aminopterin has been researched along with Breast Neoplasms in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's10 (71.43)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beinart, GA; Booser, D; Broglio, K; Dhingra, K; Frye, D; Gonzalez-Angulo, AM; Gunale, S; Holmes, FA; Hortobagyi, GN; Rosenthal, J; Walters, R; Young, JA1
HIGGINS, GM; WOODS, KA1
Campbell, DL; Perez, EA; Ryu, JK1
Buckman, RA; Eisenhauer, EA; Lopez, P; Muldal, A; Norris, BD; Pritchard, KI; Trudeau, ME; Vandenberg, TA; Verma, SS1
Chou, TC; Otter, GM; Sirotnak, FM1
Hortobagyi, GN; Ibrahim, N1
Jansen, G; Jolivet, J; Kathmann, I; Molthoff, C; Pinard, MF; Ratnam, M; Schornagel, JH; Westerhof, R1
Holmes, FA2
Bawle, EV; Conard, JV; Weiss, L1
Baselga, J; D'Andrea, G; Fennelly, D; Gilewski, T; Hudis, C; Moynahan, ME; Norton, L; Raptis, G; Seidman, AD; Sklarin, N; Surbone, A; Templeton, MA; Theodoulou, M; Yao, TJ1
Gandara, DR; Kuriakose, P; Perez, EA1
de Graeff, A; Dullemond-Westland, A; Schornagel, JH; ten Bokkel Huinink, WW; van Deijk, WA; van der Vegt, S; Verweij, J1
Budman, D; Currie, VE; Thongprasert, S1

Reviews

2 review(s) available for aminopterin and Breast Neoplasms

ArticleYear
Paclitaxel combination therapy in the treatment of metastatic breast cancer: a review.
    Seminars in oncology, 1996, Volume: 23, Issue:5 Suppl 11

    Topics: Aminopterin; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drugs, Investigational; Female; Fluorouracil; Genetic Therapy; Humans; Leucovorin; Neoplasm Metastasis; Oncogenes; Paclitaxel; Radiotherapy, Adjuvant

1996
Paclitaxel combination therapy in the treatment of metastatic breast cancer.
    Seminars in oncology, 1996, Volume: 23, Issue:5 Suppl 12

    Topics: Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Doxorubicin; Drug Interactions; Drug Synergism; Epirubicin; Fluorouracil; Humans; Ifosfamide; Neoplasm Metastasis; Paclitaxel

1996

Trials

5 trial(s) available for aminopterin and Breast Neoplasms

ArticleYear
Phase II trial of 10-EDAM in the treatment of metastatic breast cancer.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:1

    Topics: Adult; Aged; Agranulocytosis; Alopecia; Aminopterin; Anemia; Antineoplastic Agents; Breast Neoplasms; Disease Progression; Female; Humans; Leukopenia; Middle Aged; Nausea; Survival Analysis; Time Factors; Treatment Outcome

2007
Phase II study of weekly edatrexate as first-line chemotherapy for metastatic breast cancer: a National Cancer Institute of Canada Clinical Trials Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Breast Neoplasms; Drug Administration Schedule; Female; Folic Acid Antagonists; Humans; Injections, Intravenous; Middle Aged; Neoplasm Metastasis; Treatment Outcome

1993
Phase I study of escalating doses of edatrexate in combination with paclitaxel in patients with metastatic breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:2

    Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Metastasis; Paclitaxel; Treatment Outcome

1999
Phase I trial of edatrexate in advanced breast and other cancers.
    Cancer investigation, 2002, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Infusions, Intravenous; Karnofsky Performance Status; Lung Neoplasms; Maximum Tolerated Dose; Melanoma; Menopause; Middle Aged; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome

2002
Phase II study of edatrexate in chemotherapy-naive patients with metastatic breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antineoplastic Agents; Breast Neoplasms; Drug Evaluation; Female; Folic Acid Antagonists; Humans; Middle Aged; Neoplasm Metastasis

1992

Other Studies

7 other study(ies) available for aminopterin and Breast Neoplasms

ArticleYear
The effect of the folic acid antagonist, 4-aminopteroylglutamic acid, on the growth of transplanted mammary tumors in C3H mice.
    Proceedings of the staff meetings. Mayo Clinic, 1949, Apr-27, Volume: 24, Issue:9

    Topics: Aminopterin; Animals; Breast Neoplasms; Folic Acid Antagonists; Humans; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; Vitamin B Complex; Vitamins

1949
Radiation recall dermatitis induced by edatrexate in a patient with breast cancer.
    Cancer investigation, 1995, Volume: 13, Issue:6

    Topics: Adult; Aminopterin; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Drug Eruptions; Female; Humans; Radiodermatitis

1995
Schedule-dependent synergism of taxol or taxotere with edatrexate against human breast cancer cells in vitro.
    Cancer chemotherapy and pharmacology, 1996, Volume: 37, Issue:3

    Topics: Adenocarcinoma; Aminopterin; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Docetaxel; Drug Administration Schedule; Drug Synergism; Humans; Paclitaxel; Prospective Studies; Taxoids; Tumor Cells, Cultured

1996
Paclitaxel-containing combination chemotherapy for metastatic breast cancer.
    Seminars in oncology, 1996, Volume: 23, Issue:1 Suppl 1

    Topics: Aminopterin; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cyclophosphamide; Drug Administration Schedule; Female; Humans; Mitoxantrone; Paclitaxel; Vinblastine; Vinorelbine

1996
Functional aspects of membrane folate receptors in human breast cancer cells with transport-related resistance to methotrexate.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:3

    Topics: Aminopterin; Antimetabolites, Antineoplastic; Binding Sites; Breast Neoplasms; Carrier Proteins; Cell Membrane; DNA, Complementary; Female; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Polymerase Chain Reaction; Quinazolines; Receptors, Cell Surface; RNA, Messenger; Spectrometry, Fluorescence; Structure-Activity Relationship; Tetrahydrofolates; Thiophenes; Tumor Cells, Cultured

1996
Adult and two children with fetal methotrexate syndrome.
    Teratology, 1998, Volume: 57, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Abortifacient Agents; Adult; Aminopterin; Breast Neoplasms; Child; Child, Preschool; Craniofacial Abnormalities; Female; Fetal Diseases; Humans; Hypertelorism; Limb Deformities, Congenital; Male; Methotrexate; Pregnancy; Pregnancy Complications, Neoplastic; Syndrome; Teratogens

1998
Phase II trial of 10-deaza-aminopterin in advanced breast cancer.
    Cancer treatment reports, 1987, Volume: 71, Issue:1

    Topics: Adult; Aged; Aminopterin; Breast Neoplasms; Drug Evaluation; Humans; Inflammation; Middle Aged; Mucous Membrane

1987