Page last updated: 2024-09-05

aminopterin and Adenocarcinoma

aminopterin has been researched along with Adenocarcinoma in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's6 (50.00)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Azzoli, CG; Dunne, M; Ginsberg, M; Huntington, M; James, L; Kris, MG; Krug, LM; May, J; Miller, V; Patel, JD; Saunders, M; Sirotnak, FM; Subzwari, S; Tyson, L1
Abbruzzeese, J; Berghorn, E; Hausheer, F; Hoff, PM; Hutto, T; Johansen, M; Madden, T; Newman, RA; Ni, D; Zukowski, T1
Cheng, EW; Currie, VE; Yagoda, A1
Abbruzzese, JL; Ajani, JA; Belt, RJ; Bready, B; Dubovsky, DW; Mangold, C; Moore, DF; Pazdur, R; Wade, JL; Winn, RJ1
Chou, TC; Hack, FM; Perez, EA; Webber, LM1
Otter, GM; Schmid, FA; Sirotnak, FM1
Chou, TC; Otter, GM; Sirotnak, FM1
Johnson, CA; Otter, GM; Piper, JR; Ramamurthy, B; Sirotnak, FM1
Casper, ES; Johnson, B; Kelsen, DP; Schwartz, GK1
Montgomery, JA; Otter, GM; Piper, JR; Schmid, FA; Sirotnak, FM1
Hynes, JB; Kumar, A; Tomazic, A; Washtien, WL1
Periman, P; Rabson, AS; Tyrrell, S1

Trials

4 trial(s) available for aminopterin and Adenocarcinoma

ArticleYear
Pralatrexate with vitamin supplementation in patients with previously treated, advanced non-small cell lung cancer: safety and efficacy in a phase 1 trial.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2011, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Tissue Distribution; Vitamin B 12; Vitamin B Complex

2011
Final results of a phase I and pharmacokinetic study of gamma-methylene-10-deazaaminopterin (MDAM) administered intravenously daily for five consecutive days in patients with solid tumors.
    Cancer chemotherapy and pharmacology, 2004, Volume: 53, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aminopterin; Colorectal Neoplasms; Female; Folic Acid Antagonists; Humans; Male; Maximum Tolerated Dose; Methotrexate; Middle Aged

2004
Phase II trial of edatrexate in patients with advanced pancreatic adenocarcinoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminopterin; Antineoplastic Agents; Female; Humans; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Survival Rate

1994
Phase II trial of edatrexate in patients with advanced pancreatic adenocarcinoma.
    Investigational new drugs, 1992, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aminopterin; Antineoplastic Agents; Bile Duct Neoplasms; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms

1992

Other Studies

8 other study(ies) available for aminopterin and Adenocarcinoma

ArticleYear
Phase II trial of 10-deaza-aminopterin in patients with advanced colorectal cancer.
    American journal of clinical oncology, 1983, Volume: 6, Issue:4

    Topics: Adenocarcinoma; Aminopterin; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Humans; Rectal Neoplasms

1983
Schedule-dependent synergism of edatrexate and cisplatin in combination in the A549 lung-cancer cell line as assessed by median-effect analysis.
    Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Aminopterin; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Humans; Lung Neoplasms; Tumor Cells, Cultured

1993
Markedly improved efficacy of edatrexate compared to methotrexate in a high-dose regimen with leucovorin rescue against metastatic murine solid tumors.
    Cancer research, 1993, Feb-01, Volume: 53, Issue:3

    Topics: Adenocarcinoma; Aminopterin; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fibrosarcoma; Leucovorin; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma, Experimental; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Salvage Therapy

1993
Schedule-dependent synergism of taxol or taxotere with edatrexate against human breast cancer cells in vitro.
    Cancer chemotherapy and pharmacology, 1996, Volume: 37, Issue:3

    Topics: Adenocarcinoma; Aminopterin; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Docetaxel; Drug Administration Schedule; Drug Synergism; Humans; Paclitaxel; Prospective Studies; Taxoids; Tumor Cells, Cultured

1996
Analogues of 10-deazaaminopterin and 5-alkyl-5,10-dideazaaminopterin with the 4-substituted 1-naphthoyl group in the place of 4-substituted benzoyl.
    Journal of medicinal chemistry, 1996, Jan-19, Volume: 39, Issue:2

    Topics: Adenocarcinoma; Alkylation; Aminopterin; Animals; Antineoplastic Agents; Cell Division; Mammary Neoplasms, Experimental; Mice; Tumor Cells, Cultured

1996
Structural design, biochemical properties, and evidence for improved therapeutic activity of 5-alkyl derivatives of 5-deazaaminopterin and 5-deazamethotrexate compared to methotrexate in murine tumor models.
    Cancer research, 1988, Oct-15, Volume: 48, Issue:20

    Topics: Adenocarcinoma; Alkylation; Aminopterin; Animals; Drug Compounding; Epithelium; Intestine, Small; Kinetics; Mammary Neoplasms, Experimental; Methotrexate; Mice; Sarcoma 180; Structure-Activity Relationship

1988
Synthesis of 5-chloro-5,8-dideaza analogues of folic acid and aminopterin targeted for colon adenocarcinoma.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Adenocarcinoma; Aminopterin; Cell Line; Chemical Phenomena; Chemistry; Colonic Neoplasms; Humans; Quinazolines; Structure-Activity Relationship

1987
Herpesvirus saimiri in marmoset-mouse hybrid cell lines.
    Journal of the National Cancer Institute, 1972, Volume: 49, Issue:2

    Topics: Adenocarcinoma; Aminopterin; Animals; Cell Line; Chromosomes; Culture Media; Haplorhini; Herpesviridae; Hybrid Cells; In Vitro Techniques; Lymphocytes; Mice; Virus Cultivation; Virus Replication

1972