aminopropionitrile has been researched along with Pregnancy in 32 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Kyphoscoliosis was produced in a high incidence in the fetuses at the level of the upper thoracic spine as early as 24 hours after treatment." | 5.26 | Congenital kyphoscoliosis and spinal cord lesion produced in the rat by beta-aminopropionitrile. ( Nogami, H; Oohira, A; Tamaki, K; Terashima, Y, 1977) |
| "Cleft palate was induced in 420 embryos of Sprague-Dawley rats with a single oral dose of 600 mg/kg beta-aminoproprionitrile (BAPN) on embryonal day 15, 7 hours." | 1.28 | Diagnosis of induced cleft palate in rats from defective patterns of differentiation of isoenzymes. ( Granström, G; Jacobsson, C; Kirkeby, S, 1992) |
| "Kyphoscoliosis was produced in a high incidence in the fetuses at the level of the upper thoracic spine as early as 24 hours after treatment." | 1.26 | Congenital kyphoscoliosis and spinal cord lesion produced in the rat by beta-aminopropionitrile. ( Nogami, H; Oohira, A; Tamaki, K; Terashima, Y, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (84.38) | 18.7374 |
| 1990's | 4 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Segond, N | 1 |
| Degrelle, SA | 1 |
| Berndt, S | 1 |
| Clouqueur, E | 1 |
| Rouault, C | 1 |
| Saubamea, B | 1 |
| Dessen, P | 1 |
| Fong, KS | 1 |
| Csiszar, K | 1 |
| Badet, J | 1 |
| Evain-Brion, D | 1 |
| Fournier, T | 1 |
| Joneja, MG | 3 |
| Wiley, MJ | 2 |
| Salo, DF | 1 |
| Martino, LJ | 1 |
| Tucci, SM | 1 |
| Okada, E | 1 |
| Bunge, RP | 1 |
| Diewert, VM | 1 |
| Yeowell, HN | 1 |
| Marshall, MK | 1 |
| Walker, LC | 1 |
| Ha, V | 1 |
| Pinnell, SR | 1 |
| Jacobsson, C | 2 |
| Granström, G | 2 |
| Dembinski, J | 1 |
| Heyl, W | 1 |
| Steidel, K | 1 |
| Hermanns, B | 1 |
| Hörnchen, H | 1 |
| Schröder, W | 1 |
| Nogami, H | 1 |
| Terashima, Y | 1 |
| Tamaki, K | 1 |
| Oohira, A | 1 |
| Mato, M | 1 |
| Uchiyama, Y | 1 |
| Aikawa, E | 1 |
| Smiley, GR | 1 |
| Kirkeby, S | 1 |
| Simpson, MN | 1 |
| Freeman, SJ | 1 |
| Steele, CE | 1 |
| Posner, HS | 1 |
| King, CT | 3 |
| Horigan, E | 1 |
| Wilk, AL | 3 |
| Pratt, RM | 2 |
| Barrow, MV | 3 |
| Steffek, AJ | 6 |
| Bradley, KH | 1 |
| McConnell, SD | 1 |
| Crystal, RG | 1 |
| Kagan, HM | 1 |
| Hewitt, NA | 1 |
| Salcedo, LL | 1 |
| Franzblau, C | 1 |
| Hendrickx, AG | 1 |
| Nanda, V | 1 |
| Nanda, R | 1 |
| Waddell, WJ | 1 |
| Verrusio, AC | 1 |
| Watkins, CA | 1 |
| Horigan, EA | 1 |
| Simpson, CF | 1 |
| Willis, LS | 1 |
| Fyfe, FW | 1 |
| Gillman, T | 1 |
| Oneson, IB | 1 |
| Stivers, FE | 2 |
| Steffer, AJ | 1 |
| Yarington, CT | 2 |
| Roll, R | 1 |
| Bär, F | 1 |
| Herd, K | 1 |
| Orbison, JL | 1 |
1 review available for aminopropionitrile and Pregnancy
| Article | Year |
|---|---|
The Cantrell-sequence: a result of maternal exposure to aminopropionitriles?
Topics: Abnormalities, Multiple; Adult; Aminopropionitrile; Fatal Outcome; Female; Humans; Infant, Newborn; | 1997 |
31 other studies available for aminopropionitrile and Pregnancy
| Article | Year |
|---|---|
Transcriptome analysis of PPARγ target genes reveals the involvement of lysyl oxidase in human placental cytotrophoblast invasion.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Female; Gene Expression Profiling; Gene Expression R | 2013 |
Inhibition of beta-aminopropionitrile (beta APN)-induced skeletal teratogenesis by the flavonoid beta-hydroxyethylrutosides (HR) in hamster fetuses.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Bone and Bones; Collagen; Cricetinae; Fema | 1982 |
Teratogenic effects of proline analogue L-azetidine-2-carboxylic acid in hamster fetuses.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Azetidinecarboxylic Acid; Azetines; Bone a | 1981 |
Sister chromatid exchange frequency in mouse embryo chromosomes following in utero exposure to beta-aminopropionitrile.
Topics: Aminopropionitrile; Animals; Chromosomes; Crossing Over, Genetic; Dose-Response Relationship, Drug; | 1981 |
Basal lamina deficiency in Schwann cells induced by beta-aminopropionitrile (BAPN) in rat dorsal root ganglion culture.
Topics: Aminopropionitrile; Animals; Collagen; Female; Ganglia, Spinal; Microscopy, Electron; Myelin Sheath; | 1981 |
Correlation between alterations in Meckel's cartilage and induction of cleft palate with beta-aminoproprionitrile in the rat.
Topics: Aminopropionitrile; Animals; Cleft Palate; Face; Female; Gestational Age; Pregnancy; Rats; Skull | 1981 |
Regulation of lysyl oxidase mRNA in dermal fibroblasts from normal donors and patients with inherited connective tissue disorders.
Topics: Aminopropionitrile; Ascorbic Acid; Bleomycin; Cell Line; Collagen; Connective Tissue Diseases; DNA P | 1994 |
Effects of vitamin B6 on beta-aminoproprionitrile-induced palatal cleft formation in the rat.
Topics: Administration, Oral; Aminopropionitrile; Animals; Cleft Palate; Diet; Drug Interactions; Female; Ge | 1997 |
Congenital kyphoscoliosis and spinal cord lesion produced in the rat by beta-aminopropionitrile.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cartilage; Collagen; Female; Kyphosis; Pre | 1977 |
The morphogenesis of beta-aminopropionitrile-induced rib malformation in fetal golden Syrian hamsters.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cartilage; Collagen; Cricetinae; Female; G | 1978 |
Ultrastructural changes in rat palatal epithelium after beta-aminopropionitrile.
Topics: Aminopropionitrile; Animals; Animals, Newborn; Cell Nucleus; Cleft Palate; Desmosomes; Epithelium; F | 1975 |
Diagnosis of induced cleft palate in rats from defective patterns of differentiation of isoenzymes.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Amniotic Fluid; Animals; Cleft Palate; Clinical Enz | 1992 |
Embryotoxic action of beta-aminopropionitrile during early organogenesis in rats.
Topics: Aminopropionitrile; Animals; Female; Pregnancy; Rats; Rats, Inbred Strains; Teratogens | 1987 |
Significance of cleft palate induced by chemicals in the rat and mouse.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cleft Palate; Cortisone; Female; Mice; Nit | 1972 |
Fetal outcome from prolonged versus acute drug administration in the pregnant rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cleft Palate; Collagen; Demyelinating Dise | 1972 |
Inhibition of collagen cross-linking associated with beta-aminopropionitrile-induced cleft palate in the rat.
Topics: Administration, Oral; Aminopropionitrile; Animals; Cleft Palate; Collagen; Female; Gestational Age; | 1972 |
Teratologic and other embryotoxic effects of beta-aminopropionitrile in rats.
Topics: Abdominal Muscles; Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Body Weight; Bone and B | 1974 |
Lung collagen composition and synthesis. Characterization and changes with age.
Topics: Age Factors; Amino Acids; Aminopropionitrile; Animals; Animals, Newborn; Carbon Radioisotopes; Colla | 1974 |
Catalytic activity of aortic lysyl oxidase in an insoluble enzyme-substrate complex.
Topics: Amino Acid Oxidoreductases; Amino Acids; Aminopropionitrile; Animals; Antimetabolites; Aorta; Bindin | 1974 |
Lathyrogen-induced malformations in baboons: a preliminary report.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Bone and Bones; Cesarean Section; Cleft Pa | 1972 |
Cell proliferation and cell function of the mesenchymal cells of lathyritic rats, as revealed by the nuclear size.
Topics: Aminopropionitrile; Animals; Cell Division; Cell Nucleus; Female; Lathyrism; Maternal-Fetal Exchange | 1972 |
Whole-body autoradiography of the distribution of beta-aminopropionitrile in pregnant mice and rat fetuses.
Topics: Aminopropionitrile; Animals; Autoradiography; Carbon Radioisotopes; Chromatography, Thin Layer; Fema | 1974 |
Cleft palate in rodents after maternal treatment with various lathyrogenic agents.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animal Feed; Animals; Cleft Palate; Female; Nitrile | 1972 |
Metabolism of -aminopropionitrile and its teratogenic activity in rats.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Aminopropionitrile; Animals; Carbon Isotopes; Cle | 1972 |
Caution against the use of lathyrogens.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Aneurysm; Animals; Arteriosclerosis; Bone Diseases; | 1972 |
Ectopia cordis (ectocardia) and gastroschisis induced in rats by maternal administration of the lathyrogen, beta-aminopropionitrile (BAPN).
Topics: Abdomen; Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Female; Fetus; Gestational Age; H | 1972 |
A combined quantitative chemical, light, and electron microscope study of aortic development in normal and nitrile-treated mice. Possible implications for elucidating nitrile-induced aortic lesions and regarding the genesis of spontaneous arterial lesions
Topics: Aminopropionitrile; Animals; Aorta; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Collagen; De | 1968 |
The effect of lathyrogens on developing mid-facial structures in the rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Diet; Female; Jaw Abnormalities; Lathyrism | 1970 |
The effect of lathyrogens on developing midfacial structures in the rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cartilage; Cleft Palate; Diet; Face; Femal | 1971 |
[Studies on the teratogenic effect of beta-aminopropionitril in pregnant female mice].
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Bone and Bones; Embryo, Mammalian; Embryon | 1968 |
Lathyrism in the fetal rat. Evidence for impairment of elastin formation.
Topics: Aminopropionitrile; Animals; Congenital Abnormalities; Cyanides; Elastin; Female; Fetal Death; Fetal | 1966 |