aminopropionitrile has been researched along with Neoplasms in 7 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following our recently published work on the discovery of aminomethylenethiophenes (AMTs) as potent, orally bioavailable LOX/LOXL2 inhibitors, we report herein the discovery of a series of dual LOX/LOXL2 inhibitors, as well as a subseries of LOXL2-selective inhibitors, bearing an aminomethylenethiazole (AMTz) scaffold." | 1.56 | 2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth. ( Aljarah, M; Brown, M; Challinor, M; Johnson, L; Lawrence, R; Leung, LMH; Lopes, F; Marais, R; Mcleary, R; Niculescu-Duvaz, D; Pearce, SP; Smithen, DA; Springer, C; Tang, H; Thomson, G, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Smithen, DA | 1 |
| Leung, LMH | 1 |
| Challinor, M | 1 |
| Lawrence, R | 1 |
| Tang, H | 2 |
| Niculescu-Duvaz, D | 2 |
| Pearce, SP | 1 |
| Mcleary, R | 1 |
| Lopes, F | 2 |
| Aljarah, M | 1 |
| Brown, M | 1 |
| Johnson, L | 2 |
| Thomson, G | 1 |
| Marais, R | 2 |
| Springer, C | 2 |
| Sun, R | 1 |
| Wu, X | 1 |
| Mao, Y | 1 |
| Wang, H | 1 |
| Bian, C | 1 |
| Lv, P | 1 |
| Zhao, Z | 1 |
| Li, X | 1 |
| Fu, W | 1 |
| Lu, J | 1 |
| Cao, Z | 1 |
| Liburkin-Dan, T | 1 |
| Nir-Zvi, I | 1 |
| Razon, H | 1 |
| Kessler, O | 1 |
| Neufeld, G | 1 |
| Zhang, C | 1 |
| Xu, M | 1 |
| Zeng, Z | 1 |
| Wei, X | 1 |
| He, S | 1 |
| Huang, J | 1 |
| Pu, K | 1 |
| Leung, L | 1 |
| Saturno, G | 1 |
| Viros, A | 1 |
| Smith, D | 1 |
| Di Leva, G | 1 |
| Morrison, E | 1 |
| Dhomen, N | 1 |
| Granchi, C | 1 |
| Funaioli, T | 1 |
| Erler, JT | 1 |
| Giaccia, AJ | 1 |
| Macchia, M | 1 |
| Minutolo, F | 1 |
| Chvapil, M | 1 |
| Kielar, F | 1 |
| Liska, F | 1 |
| Silhankova, A | 1 |
| Brendel, K | 1 |
7 other studies available for aminopropionitrile and Neoplasms
| Article | Year |
|---|---|
2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth.
Topics: Amination; Amino Acid Oxidoreductases; Animals; Antineoplastic Agents; Enzyme Inhibitors; Female; Hu | 2020 |
A facile turn-on chemiluminescence probe for sensitive imaging on aminopeptidase N activity.
Topics: Aminopropionitrile; Animals; CD13 Antigens; Leucine; Luminescence; Mice; Molecular Docking Simulatio | 2022 |
Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated Genes.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; DNA, Complementary; HEK293 Cells; Humans; Mucoprotei | 2022 |
A Polymeric Extracellular Matrix Nanoremodeler for Activatable Cancer Photo-Immunotherapy.
Topics: Aminopropionitrile; Collagen; Extracellular Matrix; Immunotherapy; Neoplasms | 2023 |
Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface.
Topics: Aminopropionitrile; Animals; Biosensing Techniques; Cell Line, Tumor; Cell Membrane; Cell Proliferat | 2017 |
Bioreductively activated lysyl oxidase inhibitors against hypoxic tumours.
Topics: Aminopropionitrile; Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Enzyme Inhibitors; Humans | 2009 |
Synthesis and evaluation of long-acting D-penicillamine derivatives.
Topics: Adenocarcinoma; Alcohols; Aminopropionitrile; Animals; Cicatrix, Hypertrophic; Collagen; Connective | 2005 |