Page last updated: 2024-10-21

aminopropionitrile and Invasiveness, Neoplasm

aminopropionitrile has been researched along with Invasiveness, Neoplasm in 6 studies

Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.

Research Excerpts

ExcerptRelevanceReference
"However, the direct impact of LOX on cervical cancer cell motility remains poorly understood."5.39Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. ( Chen, J; Chen, L; Li, S; Li, W; Wang, Y; Xiao, X; Yan, G; Yang, X, 2013)
"However, the direct impact of LOX on cervical cancer cell motility remains poorly understood."1.39Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. ( Chen, J; Chen, L; Li, S; Li, W; Wang, Y; Xiao, X; Yan, G; Yang, X, 2013)
"The human gastric cancer cell line HGC-27 cells were cultured in vitro, and treated with different concentration of β-aminopropionitrile (BAPN)."1.37[Effect of lysyl oxidase on migration and adhesion of human gastric cancer HGC-27 cells in vitro]. ( Han, M; Huang, L; Lin, JJ; Ma, BJ; Song, TG; Sun, BJ; Wang, YQ; Zhao, JN, 2011)
"Treatment of the invasive breast cancer cell lines, Hs578T and MDA-MB-231, with beta-aminopropionitrile (betaAPN), an irreversible inhibitor of LOX catalytic activity, leads to a significant decrease in cell motility/migration and adhesion formation."1.33Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism. ( Csiszar, K; Fogelgren, B; Fong, SF; Hendrix, MJ; Hess, AR; Kirschmann, DA; Payne, SL; Seftor, EA; Wiley, EL, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ma, BJ1
Huang, L1
Han, M1
Wang, YQ1
Zhao, JN1
Sun, BJ1
Lin, JJ1
Song, TG1
Yang, X1
Li, S1
Li, W1
Chen, J1
Xiao, X1
Wang, Y1
Yan, G1
Chen, L1
Teppo, S1
Sundquist, E1
Vered, M1
Holappa, H1
Parkkisenniemi, J1
Rinaldi, T1
Lehenkari, P1
Grenman, R1
Dayan, D1
Risteli, J1
Salo, T1
Nyberg, P1
Kirschmann, DA2
Seftor, EA2
Fong, SF2
Nieva, DR1
Sullivan, CM1
Edwards, EM1
Sommer, P2
Csiszar, K2
Hendrix, MJ2
Payne, SL1
Fogelgren, B1
Hess, AR1
Wiley, EL1
Bouez, C1
Reynaud, C1
Noblesse, E1
Thépot, A1
Gleyzal, C1
Kanitakis, J1
Perrier, E1
Damour, O1

Other Studies

6 other studies available for aminopropionitrile and Invasiveness, Neoplasm

ArticleYear
[Effect of lysyl oxidase on migration and adhesion of human gastric cancer HGC-27 cells in vitro].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:5

    Topics: Aminopropionitrile; Cell Adhesion; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug

2011
Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells.
    Oncology reports, 2013, Volume: 29, Issue:2

    Topics: Actins; Aminopropionitrile; Cadherins; Cell Movement; Enzyme Inhibitors; Epithelial-Mesenchymal Tran

2013
The hypoxic tumor microenvironment regulates invasion of aggressive oral carcinoma cells.
    Experimental cell research, 2013, Feb-15, Volume: 319, Issue:4

    Topics: Aged; Aminopropionitrile; Carcinoma, Squamous Cell; Cell Migration Assays; Cell Movement; Enzyme Inh

2013
A molecular role for lysyl oxidase in breast cancer invasion.
    Cancer research, 2002, Aug-01, Volume: 62, Issue:15

    Topics: Aminopropionitrile; Breast Neoplasms; Enzyme Inhibitors; Humans; Isoenzymes; Neoplasm Invasiveness;

2002
Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism.
    Cancer research, 2005, Dec-15, Volume: 65, Issue:24

    Topics: Aminopropionitrile; Breast Neoplasms; Catalase; Cell Adhesion; Cell Movement; Enzyme Activation; Fem

2005
The lysyl oxidase LOX is absent in basal and squamous cell carcinomas and its knockdown induces an invading phenotype in a skin equivalent model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Mar-01, Volume: 12, Issue:5

    Topics: Aminopropionitrile; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cells, Cultured; Collagen; Derm

2006