aminopropionitrile has been researched along with Inflammation in 11 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using an aortic dissection model in SR-A1-deficient mice and their wild type littermates, we found that SR-A1 deficiency aggravated beta-aminopropionitrile monofumarate induced thoracic aortic dilation, false lumen formation, extracellular matrix degradation, vascular inflammation and accumulation of apoptotic cells." | 3.91 | Scavenger receptor A1 attenuates aortic dissection via promoting efferocytosis in macrophages. ( Bai, H; Ben, J; Chen, Q; Chen, S; Huang, J; Jiang, Y; Li, X; Yang, Q; Zhang, H; Zhang, Z; Zhou, W; Zhou, Z; Zhu, X, 2019) |
| "However, the role of IL-5 in acute aortic dissection (AAD) has barely been explored." | 1.56 | IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis. ( Ren, Q; Ren, W; Ruan, Y; Wang, J; Wang, Z; Wu, Z; Yu, A, 2020) |
| "Acute aortic dissection is one of the most lethal cardiovascular disease." | 1.48 | CD40L promotes development of acute aortic dissection via induction of inflammation and impairment of endothelial cell function. ( Dai, L; Han, L; Jiang, WJ; Lan, F; Li, HY; Liu, O; Zhang, HJ; Zhao, YF, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, C | 2 |
| Niu, K | 1 |
| Ren, M | 1 |
| Zhou, X | 1 |
| Yang, Z | 1 |
| Yang, M | 1 |
| Wang, X | 1 |
| Luo, J | 2 |
| Shao, Y | 1 |
| Chen, D | 1 |
| Gao, S | 1 |
| Ge, S | 1 |
| Wu, Q | 1 |
| Xiao, Q | 1 |
| Zhu, L | 1 |
| An, P | 1 |
| Zhao, W | 1 |
| Xia, Y | 1 |
| Qi, J | 1 |
| Luo, Y | 1 |
| Ren, W | 1 |
| Wang, Z | 1 |
| Wang, J | 1 |
| Wu, Z | 1 |
| Ren, Q | 1 |
| Yu, A | 1 |
| Ruan, Y | 1 |
| Han, L | 1 |
| Dai, L | 1 |
| Zhao, YF | 1 |
| Li, HY | 1 |
| Liu, O | 1 |
| Lan, F | 1 |
| Jiang, WJ | 1 |
| Zhang, HJ | 2 |
| Zhang, Z | 1 |
| Jiang, Y | 1 |
| Zhou, Z | 1 |
| Huang, J | 1 |
| Chen, S | 1 |
| Zhou, W | 1 |
| Yang, Q | 1 |
| Bai, H | 1 |
| Zhang, H | 1 |
| Ben, J | 1 |
| Zhu, X | 1 |
| Li, X | 1 |
| Chen, Q | 1 |
| Jia, LX | 1 |
| Zhang, WM | 1 |
| Li, TT | 1 |
| Wang, YL | 1 |
| Qin, YW | 1 |
| Gu, H | 1 |
| Du, J | 1 |
| BRUEMMER, NC | 1 |
| LALICH, JJ | 1 |
| MUELLER, GC | 1 |
| GRIES, G | 1 |
| LINDNER, J | 1 |
| Chvapil, M | 1 |
| Pierce, GF | 1 |
| Brown, D | 1 |
| Mustoe, TA | 1 |
| Joós, A | 1 |
| Kádár, A | 1 |
| Jellinek, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety And Efficacy Of Topical Platelet Rich Plasma And Thrombin Coagulum In The Treatment Of Recalcitrant Venous Stasis Ulcers[NCT02802995] | Phase 3 | 15 participants (Actual) | Interventional | 2016-05-31 | Terminated (stopped due to Resource issue) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 other studies available for aminopropionitrile and Inflammation
| Article | Year |
|---|---|
Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease Models, Animal; Elastin; Hum | 2022 |
Low Zinc Alleviates the Progression of Thoracic Aortic Dissection by Inhibiting Inflammation.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease | 2023 |
IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Dissection; Apoptosis; Case-Control Studi | 2020 |
CD40L promotes development of acute aortic dissection via induction of inflammation and impairment of endothelial cell function.
Topics: Aminopropionitrile; Animals; Aortic Dissection; Blood Platelets; Case-Control Studies; CD40 Ligand; | 2018 |
Scavenger receptor A1 attenuates aortic dissection via promoting efferocytosis in macrophages.
Topics: Aminopropionitrile; Animals; Aortic Dissection; Apoptosis; Enzyme Inhibitors; Gene Expression Regula | 2019 |
Mechanical stretch-induced endoplasmic reticulum stress, apoptosis and inflammation contribute to thoracic aortic aneurysm and dissection.
Topics: Activating Transcription Factor 4; Aminopropionitrile; Animals; Aorta; Aortic Aneurysm, Thoracic; Ap | 2015 |
Effect of beta-aminopropionitrile on incorporation of glycine by croton oil pouches in rats.
Topics: Abdominal Wall; Aminopropionitrile; Animals; Croton Oil; Cyanides; Fabaceae; Glycine; Inflammation; | 1957 |
[COMPARATIVE STUDIES ON THE COLLAGEN BREAKDOWN IN INFLAMED AND LATHYRITICALLY CHANGED TISSUES].
Topics: Aminopropionitrile; Collagen; Cyanides; Hydroxyproline; Inflammation; Lathyrism; Rats; Research; Ten | 1963 |
Pharmacology of fibrosis: definitions, limits and perspectives.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid Deficiency; Biopo | 1975 |
Quantitative analysis of inflammatory cell influx, procollagen type I synthesis, and collagen cross-linking in incisional wounds: influence of PDGF-BB and TGF-beta 1 therapy.
Topics: Aminopropionitrile; Animals; Collagen; Fibroblasts; Inflammation; Macrophages; Monocytes; Neutrophil | 1991 |
[Changes caused by copper deficient diet and beta amino propionitrile administration in chickens].
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Aorta; Chick Embryo; Chickens; Copper; Die | 1974 |