aminopropionitrile has been researched along with Disease Models, Animal in 103 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Angiotensin II (AngII) has been widely used to promotes aortic dissections in mice." | 8.12 | Smooth Muscle Cell Relaxation Worsens Aortic Dilatation and Clinical Presentation in a BAPN/Angiotensin II-Induced Aortic Dissection Model in Rats. ( Darmon, A; Dupont, S; El Bitar, S; Jondeau, G; Michel, JB; Pellenc, Q, 2022) |
| "Given the controversy regarding the appropriate dose of β-aminopropionitrile for induction of aortic dissection models in rats, the purpose of this study was to explore the most suitable concentration of β-aminopropionitrile to establish a high-incidence and low-mortality aortic dissection model." | 8.02 | Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats. ( Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X, 2021) |
| " The model was established by administering angiotensin II (Ang II) and β-aminopropionitrile (BAPN), a lysyl oxidase inhibitor, to mice to induce hypertension and degeneration of the elastic lamina, which would eventually result in the onset of an aortic aneurysm." | 7.96 | Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice. ( Chuma, M; Goda, M; Hosooka, M; Ishizawa, K; Izawa-Ishizawa, Y; Kagimoto, Y; Kondo, M; Matsuoka, R; Saito, N; Takechi, K; Tsuneyama, K; Yagi, K; Zamami, Y, 2020) |
| "NO-NIF has the potential to be a new, nifedipine-derived therapeutic drug for suppressing aortic aneurysm formation by directly improving aortic structure with its strong ability to reduce oxidative stress and inflammation." | 7.88 | Nitrosonifedipine, a Photodegradation Product of Nifedipine, Suppresses Pharmacologically Induced Aortic Aneurysm Formation. ( Chuma, M; Fujino, H; Fukushima, K; Horinouchi, Y; Ikeda, Y; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kohara, Y; Sairyo, E; Sakurada, T; Takechi, K; Tamaki, T; Tsuchiya, K; Yoshizumi, M; Zamami, Y, 2018) |
| "This study compared three β-aminopropionitrile (BAPN) treatment rats to find the optimal BAPN model for thoracic aortic dissection and aneurysm in one study." | 7.79 | Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage. ( Jing, ZP; Li, HY; Li, JS; Wang, L; Zhang, L, 2013) |
| "25% beta-aminopropionitrile monofumarate (BAPN)-induced aortic dissection and histopathologic findings in a rat model." | 7.71 | An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats. ( Aoka, Y; Aomi, S; Hagiwara, N; Kasanuki, H; Kawana, M; Nagashima, H; Sakomura, Y; Sakuta, A; Uto, K, 2002) |
| "Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices." | 5.56 | Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020) |
| "This study uncovered an important and previously unrecognized role of hyperuricemia in mediating the pathogenesis of TAAD, and uric acid-lowering drug may represent a promising therapeutic approach for TAAD." | 4.31 | Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice. ( Cai, Z; Dai, R; Fu, Y; Gong, Z; Kong, W; Li, W; Li, Z; Luo, C; Shen, Y; Wang, J; Wu, H; Yang, L; Yu, F; Zhang, T; Zhang, X; Zhao, H; Zhao, Y; Zhu, J, 2023) |
| "The clamped rat aorta showed luminal dilation, elastin fiber breaks, neointimal hyperplasia, and dissection (days 0-90)." | 4.12 | Intramural injection of pluronic gel loaded with drugs to alleviate arterial injury. ( Bai, H; Dardik, A; Sun, P; Wei, S; Xing, Y; Zhang, L, 2022) |
| " Angiotensin II (AngII) has been widely used to promotes aortic dissections in mice." | 4.12 | Smooth Muscle Cell Relaxation Worsens Aortic Dilatation and Clinical Presentation in a BAPN/Angiotensin II-Induced Aortic Dissection Model in Rats. ( Darmon, A; Dupont, S; El Bitar, S; Jondeau, G; Michel, JB; Pellenc, Q, 2022) |
| "Angiotensin II (AngII) is a potential contributor to the development of abdominal aortic aneurysm (AAA)." | 4.02 | Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm. ( Choi, ET; Cicalese, S; Cooper, HA; Eguchi, S; Kasahara, S; Kawai, T; Okuno, K; Otaka, N; Preston, KJ; Rizzo, V; Scalia, R; Uchida, HA, 2021) |
| "Given the controversy regarding the appropriate dose of β-aminopropionitrile for induction of aortic dissection models in rats, the purpose of this study was to explore the most suitable concentration of β-aminopropionitrile to establish a high-incidence and low-mortality aortic dissection model." | 4.02 | Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats. ( Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X, 2021) |
| " The model was established by administering angiotensin II (Ang II) and β-aminopropionitrile (BAPN), a lysyl oxidase inhibitor, to mice to induce hypertension and degeneration of the elastic lamina, which would eventually result in the onset of an aortic aneurysm." | 3.96 | Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice. ( Chuma, M; Goda, M; Hosooka, M; Ishizawa, K; Izawa-Ishizawa, Y; Kagimoto, Y; Kondo, M; Matsuoka, R; Saito, N; Takechi, K; Tsuneyama, K; Yagi, K; Zamami, Y, 2020) |
| "NO-NIF has the potential to be a new, nifedipine-derived therapeutic drug for suppressing aortic aneurysm formation by directly improving aortic structure with its strong ability to reduce oxidative stress and inflammation." | 3.88 | Nitrosonifedipine, a Photodegradation Product of Nifedipine, Suppresses Pharmacologically Induced Aortic Aneurysm Formation. ( Chuma, M; Fujino, H; Fukushima, K; Horinouchi, Y; Ikeda, Y; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kohara, Y; Sairyo, E; Sakurada, T; Takechi, K; Tamaki, T; Tsuchiya, K; Yoshizumi, M; Zamami, Y, 2018) |
| "Angiotensin II (Ang II) has been implicated in the development of abdominal aortic aneurysm (AAA)." | 3.81 | Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model. ( Choi, E; Daugherty, A; Eguchi, S; Elliott, KJ; Forrester, SJ; Fukuda, Y; Kawai, T; Kobayashi, T; Obama, T; Rizzo, V; Takayanagi, T; Taro, Y; Tsuji, T, 2015) |
| "This study compared three β-aminopropionitrile (BAPN) treatment rats to find the optimal BAPN model for thoracic aortic dissection and aneurysm in one study." | 3.79 | Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage. ( Jing, ZP; Li, HY; Li, JS; Wang, L; Zhang, L, 2013) |
| "To investigate thoracic aortic longitudinal elastic strength in β-aminopropionitrile (BAPN) treated rat model of aortic dissection (AD)." | 3.78 | [Biomechanical properties study of aorta in β-aminopropionitrile-induced rat model]. ( Bao, JM; Jing, ZP; Lin, C; Lu, H; Lu, QS; Wang, L; Zhang, L, 2012) |
| "25% beta-aminopropionitrile monofumarate (BAPN)-induced aortic dissection and histopathologic findings in a rat model." | 3.71 | An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats. ( Aoka, Y; Aomi, S; Hagiwara, N; Kasanuki, H; Kawana, M; Nagashima, H; Sakomura, Y; Sakuta, A; Uto, K, 2002) |
| "We studied ventilation distribution using the single-breath washout technique in rats with two types of induced emphysema: panacinar-like (by instilled elastase) and centriacinar-like (by inhaled CdCl2 combined with oral intake of beta-aminopropionitrile)." | 3.70 | Intrapulmonary gas mixing in panacinar- and centriacinar-induced emphysema in rats. ( González Mangado, N; Paiva, M; Peces-Barba, G; Rubio, ML; Sánchez-Cifuentes, MV; Verbanck, S, 1998) |
| "Saccular cerebral aneurysms were successfully induced in two monkeys treated with ligation of the common carotid artery, experimental hypertension, and beta-aminopropionitrile feeding." | 3.67 | Experimental induction of cerebral aneurysms in monkeys. ( Hashimoto, N; Hazama, F; Kang, Y; Kikuchi, H; Kim, C; Kojima, M, 1987) |
| "The underlying etiology of the toxic oil syndrome may be related to any of several toxic contaminants." | 2.38 | Synergistic vascular toxicity and fatty acid anilides in the toxic oil syndrome. ( Ansari, GA; Boor, PJ; Jerrells, TR; Kaphalia, BS; Khan, MF, 1991) |
| "While fibrosis is primarily characterized by an accumulation of extracellular matrix (ECM) components, there are changes in ECM architecture during fibrosis that relate more closely to functional muscle stiffness." | 1.72 | Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor. ( Brashear, SE; Christiansen, BA; Hu, LY; Jbeily, EH; Smith, LR; Wohlgemuth, RP, 2022) |
| "The incidence and mortality of aortic dissection (AD) are increasing." | 1.72 | ALDH ( Cui, Y; Liu, Z; Luo, C; Wang, S; Zhou, B, 2022) |
| "Thoracic aortic dissection (TAD) is associated with matrix changes, biochemical changes, and inflammatory markers like interleukin-1 beta (IL-1β)." | 1.56 | Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model. ( Chu, YX; Guo, LL; Jing, ZP; Li, JS; Sun, YD; Tian, P; Wu, MT; Yeung, KK; Zhang, L; Zhang, LW, 2020) |
| "However, the role of IL-5 in acute aortic dissection (AAD) has barely been explored." | 1.56 | IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis. ( Ren, Q; Ren, W; Ruan, Y; Wang, J; Wang, Z; Wu, Z; Yu, A, 2020) |
| "Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices." | 1.56 | Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020) |
| "Large animal models to study abdominal aortic aneurysms are sparse." | 1.51 | Porcine Model of Infrarenal Abdominal Aortic Aneurysm. ( Ailawadi, G; Cullen, JM; Dahl, JJ; Johnston, WF; Lu, G; Montgomery, WG; Salmon, M; Scott, EJ; Shannon, AH; Spinosa, MD; Tyerman, Z; Upchurch, GR, 2019) |
| "Aortic dissection is a severe inflammatory vascular disease with high mortality and limited therapeutic options." | 1.51 | Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway ( Jiang, C; Kong, W; Li, X; Lian, G; Liu, H; Pang, Y; Sun, L; Wang, X; Zhang, L; Zhang, T; Zhang, X; Zhang, Y, 2019) |
| "β-Aminopropionitrile (BAPN) is a compound known to cause aortic aneurysms by inhibiting lysyl oxidase, a collagen cross-linking enzyme." | 1.51 | A novel swine model of abdominal aortic aneurysm. ( Ailawadi, G; Cullen, JM; Fashandi, AZ; Johnston, WF; Lu, G; Montgomery, WG; Salmon, M; Shannon, AH; Sharma, A; Spinosa, MD; Su, G; Upchurch, GR, 2019) |
| " A mouse model of lathyrism using subcutaneous injection of up to 500 mg/kg β-aminopropionitrile (BAPN) was developed and characterized (60 animals across 4 dosage groups)." | 1.42 | Bone fracture toughness and strength correlate with collagen cross-link maturity in a dose-controlled lathyrism mouse model. ( Gong, B; Kohn, DH; McNerny, EM; Morris, MD, 2015) |
| "Azelnidipine treatment reduced the pathologic findings normally associated with aneurysm formation within the aortic wall." | 1.39 | Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects. ( Hirata, Y; Kitagawa, T; Kurobe, H; Matsuoka, Y; Maxfield, MW; Sata, M; Sugasawa, N, 2013) |
| " A β-APN dosage of 5 mg/0." | 1.38 | Effect of defective collagen synthesis on epithelial implant interface: lathyritic model in dogs. An experimental preliminary study. ( Acikgoz, G; Cengiz, MI; Kirtiloğlu, T; Trisi, P; Wang, HL, 2012) |
| "In the experimental group, lathyrism was induced by a once daily subcutaneous administration of beta-APN at a dose of 5mg in 0." | 1.35 | Ultrastructural and histomorphometric alterations of rat jaw bones after experimental induction of lathyrism. ( Bashir, MH; El Rouby, DH; Korany, NS, 2008) |
| "Lathyrism has been reviewed in respect to four overlapping phases: finding an animal model for neurolathyrism, characterizing osteolathyrism in respect to its possible use as an animal model for human diseases, such as Marfan's syndrome, idiopathic juvenile scoliosis, etc." | 1.27 | Lathyrism: mini-review and a comment on the lack of effect of protease inhibitors on osteolathyrism. ( Arunatut, O; Buranarugsa, MW; Yeager, VL, 1985) |
| "The induction of centriacinar emphysema was attributed specifically to NO2 exposure." | 1.27 | Nitrogen-dioxide-induced emphysema in rats. Lack of worsening by beta-aminopropionitrile treatment. ( Blank, J; Burdette, L; Glasgow, JE; Pietra, GG; Weinbaum, G, 1988) |
| "Cerebral aneurysms were induced in rats treated with unilateral ligation of the common carotid artery and hypertension produced by renal infarction with or without beta-aminopropionitrile, one of the lathyrogens." | 1.26 | Experimentally induced cerebral aneurysms in rats: Part VI. Hypertension. ( Handa, H; Hashimoto, N; Hazama, F; Nagata, I, 1980) |
| "Histological evaluation of the treated scar tissue was consistent with lathyrism." | 1.26 | Inhibition of collagen cross-linking: a new approach to ocular scarring. ( Moorhead, LC, 1981) |
| "Among them, cerebral aneurysms were never found in rats without carotid ligation." | 1.26 | Experimentally induced cerebral aneurysms in rats: Part V. Relation of hemodynamics in the circle of Willis to formation of aneurysms. ( Handa, H; Hashimoto, N; Hazama, F; Nagata, I, 1980) |
| "Experimental cerebral aneurysms were induced in rats in which the left carotid artery was ligated." | 1.26 | Experimental intracranial aneurysms in rats. A gross and microscopic study. ( Popoff, N; Robertson, JT; Stadlan, EM; Suzuki, S; White, RP, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (23.30) | 18.7374 |
| 1990's | 6 (5.83) | 18.2507 |
| 2000's | 2 (1.94) | 29.6817 |
| 2010's | 36 (34.95) | 24.3611 |
| 2020's | 35 (33.98) | 2.80 |
| Authors | Studies |
|---|---|
| Rowbottom, MW | 1 |
| Bain, G | 1 |
| Calderon, I | 1 |
| Lasof, T | 1 |
| Lonergan, D | 1 |
| Lai, A | 1 |
| Huang, F | 1 |
| Darlington, J | 1 |
| Prodanovich, P | 1 |
| Santini, AM | 1 |
| King, CD | 1 |
| Goulet, L | 1 |
| Shannon, KE | 1 |
| Ma, GL | 1 |
| Nguyen, K | 1 |
| MacKenna, DA | 1 |
| Evans, JF | 1 |
| Hutchinson, JH | 1 |
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 3 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Zhang, S | 2 |
| Liu, Z | 3 |
| Xie, N | 2 |
| Huang, C | 1 |
| Li, Z | 3 |
| Yu, F | 2 |
| Fu, Y | 5 |
| Cui, Q | 1 |
| Kong, W | 6 |
| Ding, YC | 1 |
| Zhang, XJ | 1 |
| Zhang, JX | 1 |
| Zhai, ZY | 1 |
| Zhang, MX | 1 |
| Jiang, BH | 1 |
| Berman, AG | 3 |
| Romary, DJ | 2 |
| Kerr, KE | 1 |
| Gorazd, NE | 1 |
| Wigand, MM | 1 |
| Patnaik, SS | 1 |
| Finol, EA | 1 |
| Cox, AD | 1 |
| Goergen, CJ | 3 |
| Tan, Y | 1 |
| Reed-Maldonado, AB | 2 |
| Wang, G | 2 |
| Banie, L | 2 |
| Peng, D | 1 |
| Zhou, F | 1 |
| Chen, Y | 1 |
| Wang, Z | 3 |
| Lin, G | 2 |
| Lue, TF | 2 |
| Bai, H | 1 |
| Sun, P | 1 |
| Wei, S | 1 |
| Zhang, L | 7 |
| Xing, Y | 1 |
| Dardik, A | 1 |
| Sawada, H | 2 |
| Ohno-Urabe, S | 3 |
| Ye, D | 1 |
| Franklin, MK | 2 |
| Moorleghen, JJ | 1 |
| Howatt, DA | 1 |
| Mullick, AE | 1 |
| Daugherty, A | 3 |
| Lu, HS | 2 |
| Luo, C | 2 |
| Zhou, B | 2 |
| Cui, Y | 1 |
| Wang, S | 2 |
| Zhang, C | 3 |
| Niu, K | 1 |
| Ren, M | 1 |
| Zhou, X | 1 |
| Yang, Z | 1 |
| Yang, M | 1 |
| Wang, X | 3 |
| Luo, J | 2 |
| Shao, Y | 3 |
| Chen, D | 2 |
| Gao, S | 1 |
| Ge, S | 1 |
| Wu, Q | 1 |
| Xiao, Q | 1 |
| Brashear, SE | 1 |
| Wohlgemuth, RP | 1 |
| Hu, LY | 1 |
| Jbeily, EH | 1 |
| Christiansen, BA | 1 |
| Smith, LR | 1 |
| Pellenc, Q | 1 |
| El Bitar, S | 1 |
| Darmon, A | 1 |
| Dupont, S | 1 |
| Michel, JB | 1 |
| Jondeau, G | 1 |
| Gong, Z | 3 |
| Huang, J | 1 |
| Wang, D | 1 |
| Yang, S | 1 |
| Ma, Z | 1 |
| Ma, Q | 1 |
| Okuno, K | 2 |
| Torimoto, K | 1 |
| Cicalese, SM | 1 |
| Hashimoto, T | 1 |
| Sparks, MA | 1 |
| Rizzo, V | 3 |
| Eguchi, S | 3 |
| Zhu, L | 1 |
| An, P | 1 |
| Zhao, W | 1 |
| Xia, Y | 1 |
| Qi, J | 1 |
| Luo, Y | 1 |
| Yang, L | 1 |
| Wu, H | 1 |
| Zhao, Y | 2 |
| Dai, R | 2 |
| Zhang, X | 4 |
| Cai, Z | 1 |
| Shen, Y | 1 |
| Zhao, H | 2 |
| Zhang, T | 2 |
| Zhu, J | 1 |
| Wang, J | 2 |
| Weiss, D | 3 |
| Rego, BV | 2 |
| Cavinato, C | 2 |
| Li, DS | 1 |
| Kawamura, Y | 1 |
| Emuna, N | 1 |
| Humphrey, JD | 2 |
| Huang, SS | 1 |
| Liu, R | 1 |
| Chang, S | 1 |
| Li, X | 2 |
| Weng, X | 1 |
| Ge, J | 1 |
| Lian, G | 1 |
| Zhang, Y | 1 |
| Sun, L | 1 |
| Liu, H | 3 |
| Pang, Y | 1 |
| Jiang, C | 1 |
| Atluri, K | 1 |
| Brouillette, MJ | 1 |
| Seol, D | 1 |
| Khorsand, B | 1 |
| Sander, E | 1 |
| Salem, AK | 1 |
| Fredericks, D | 1 |
| Petersen, E | 1 |
| Smith, S | 1 |
| Fowler, TP | 1 |
| Martin, JA | 1 |
| Fashandi, AZ | 3 |
| Spinosa, M | 1 |
| Salmon, M | 3 |
| Su, G | 5 |
| Montgomery, W | 1 |
| Mast, A | 1 |
| Lu, G | 5 |
| Hawkins, RB | 2 |
| Cullen, JM | 4 |
| Sharma, AK | 2 |
| Ailawadi, G | 6 |
| Upchurch, GR | 7 |
| Shannon, AH | 2 |
| Dahl, JJ | 1 |
| Scott, EJ | 1 |
| Tyerman, Z | 1 |
| Spinosa, MD | 3 |
| Montgomery, WG | 3 |
| Johnston, WF | 2 |
| Ren, W | 2 |
| Wu, Z | 1 |
| Ren, Q | 1 |
| Yu, A | 1 |
| Ruan, Y | 2 |
| Shimoda, Y | 1 |
| Nakayama, N | 1 |
| Moriwaki, T | 1 |
| Abumiya, T | 1 |
| Kawabori, M | 1 |
| Kurisu, K | 1 |
| Gekka, M | 1 |
| Hokari, M | 1 |
| Ito, Y | 1 |
| Houkin, K | 1 |
| Wu, AK | 1 |
| Zaid, U | 1 |
| Villalta, JD | 1 |
| Wang, K | 1 |
| Zhao, J | 1 |
| Zhang, W | 2 |
| Zhu, M | 1 |
| Xu, M | 1 |
| Li, D | 1 |
| Shi, H | 1 |
| Zhang, M | 1 |
| Shi, J | 1 |
| Dong, Z | 1 |
| Lu, H | 2 |
| Sun, J | 2 |
| Liang, W | 1 |
| Chang, Z | 1 |
| Rom, O | 1 |
| Zhao, G | 3 |
| Xiong, W | 1 |
| Wang, H | 1 |
| Zhu, T | 1 |
| Guo, Y | 1 |
| Chang, L | 1 |
| Garcia-Barrio, MT | 1 |
| Zhang, J | 1 |
| Chen, YE | 1 |
| Fan, Y | 1 |
| Cooper, HA | 1 |
| Cicalese, S | 1 |
| Preston, KJ | 1 |
| Kawai, T | 2 |
| Choi, ET | 1 |
| Kasahara, S | 1 |
| Uchida, HA | 1 |
| Otaka, N | 1 |
| Scalia, R | 1 |
| Hayashi-Hori, M | 1 |
| Aoki, H | 2 |
| Matsukuma, M | 1 |
| Majima, R | 1 |
| Hashimoto, Y | 1 |
| Ito, S | 1 |
| Hirakata, S | 1 |
| Nishida, N | 1 |
| Furusho, A | 1 |
| Fukumoto, Y | 1 |
| Li, G | 2 |
| Huang, S | 1 |
| Qiao, B | 1 |
| Li, Y | 2 |
| Du, J | 4 |
| Li, P | 2 |
| Guo, LL | 1 |
| Wu, MT | 1 |
| Zhang, LW | 1 |
| Chu, YX | 1 |
| Tian, P | 1 |
| Jing, ZP | 4 |
| Li, JS | 2 |
| Sun, YD | 1 |
| Yeung, KK | 1 |
| Kondo, M | 1 |
| Izawa-Ishizawa, Y | 2 |
| Goda, M | 1 |
| Hosooka, M | 1 |
| Kagimoto, Y | 1 |
| Saito, N | 1 |
| Matsuoka, R | 1 |
| Zamami, Y | 2 |
| Chuma, M | 2 |
| Yagi, K | 1 |
| Takechi, K | 2 |
| Tsuneyama, K | 1 |
| Ishizawa, K | 2 |
| Qi, X | 1 |
| Wang, F | 1 |
| Chun, C | 1 |
| Saldarriaga, L | 1 |
| Jiang, Z | 2 |
| Pruitt, EY | 1 |
| Arnaoutakis, GJ | 1 |
| Lv, X | 1 |
| Hu, Y | 1 |
| Chen, X | 2 |
| Chen, L | 1 |
| Lin, Y | 1 |
| Hou, Y | 1 |
| von Kleeck, R | 1 |
| Roberts, E | 1 |
| Castagnino, P | 1 |
| Bruun, K | 1 |
| Brankovic, SA | 1 |
| Hawthorne, EA | 1 |
| Xu, T | 1 |
| Tobias, JW | 1 |
| Assoian, RK | 1 |
| Kukida, M | 1 |
| Katsumata, Y | 2 |
| Su, W | 1 |
| Gong, MC | 1 |
| Chen, SW | 1 |
| Chou, SH | 1 |
| Tung, YC | 1 |
| Hsiao, FC | 1 |
| Ho, CT | 1 |
| Chan, YH | 1 |
| Wu, VC | 1 |
| Chou, AH | 1 |
| Hsu, ME | 1 |
| Lin, PJ | 1 |
| Kao, WWY | 1 |
| Chu, PH | 1 |
| Latorre, M | 1 |
| Tanski, BJ | 1 |
| Zheng, X | 1 |
| Yang, X | 1 |
| Yuan, Y | 1 |
| Li, M | 1 |
| Chen, Q | 1 |
| Me, R | 1 |
| Yu, Y | 1 |
| Gu, Q | 1 |
| Shi, G | 1 |
| Ke, B | 1 |
| Salmon, MD | 1 |
| Gao, L | 1 |
| Wu, C | 1 |
| Fu, F | 1 |
| You, X | 1 |
| Ma, X | 1 |
| Qin, F | 1 |
| Li, T | 1 |
| Wang, R | 1 |
| Yuan, J | 1 |
| Lai, H | 1 |
| Zhao, X | 1 |
| Qin, Y | 1 |
| Ding, Y | 1 |
| Chen, R | 1 |
| Labrie, M | 1 |
| Ding, Z | 1 |
| Zhou, J | 1 |
| Hu, J | 1 |
| Ma, D | 1 |
| Fang, Y | 1 |
| Gao, Q | 1 |
| Liu, C | 1 |
| Jia, L | 2 |
| Chen, B | 1 |
| Liu, L | 1 |
| You, B | 1 |
| Liu, Y | 2 |
| He, L | 1 |
| Yu, C | 1 |
| Zhao, T | 1 |
| Cao, F | 1 |
| Gao, Y | 1 |
| Zheng, J | 1 |
| Imanishi, M | 2 |
| Sakurada, T | 1 |
| Kohara, Y | 1 |
| Horinouchi, Y | 1 |
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| Tamaki, T | 2 |
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2 reviews available for aminopropionitrile and Disease Models, Animal
| Article | Year |
|---|---|
Synergistic vascular toxicity and fatty acid anilides in the toxic oil syndrome.
Topics: Allylamine; Aminopropionitrile; Anilides; Animals; Brassica; Cooking; Disease Models, Animal; Drug S | 1991 |
Experimental myopia in tree shrews.
Topics: Aminopropionitrile; Animals; Collagen; Disease Models, Animal; Eye; Eyelids; Myopia; Tupaiidae; Visi | 1990 |
101 other studies available for aminopropionitrile and Disease Models, Animal
| Article | Year |
|---|---|
Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2).
Topics: Administration, Oral; Amino Acid Oxidoreductases; Animals; Disease Models, Animal; Enzyme Inhibitors | 2017 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Pan-HDAC (Histone Deacetylase) Inhibitors Increase Susceptibility of Thoracic Aortic Aneurysm and Dissection in Mice.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cefixime | 2021 |
Progression and Regression of Abdominal Aortic Aneurysms in Mice.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Abdominal; Collagen; Disease Models, Animal; Disease P | 2021 |
Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition.
Topics: Administration, Topical; Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; | 2022 |
Microenergy acoustic pulse therapy restores urethral wall integrity and continence in a rat model of female stress incontinence.
Topics: Acoustics; Aminopropionitrile; Animals; Disease Models, Animal; Female; Rats; Rats, Sprague-Dawley; | 2022 |
Intramural injection of pluronic gel loaded with drugs to alleviate arterial injury.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Disease Models, Animal; Elastin; Hyperplasia; Lipopol | 2022 |
Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile-Induced Thoracic Aortopathy in Mice-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Angiotensinogen; Animals; Aortic Aneurysm, Thoracic; Aortic Rupt | 2022 |
ALDH
Topics: Aldehyde Dehydrogenase, Mitochondrial; Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aorti | 2022 |
Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease Models, Animal; Elastin; Hum | 2022 |
Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor.
Topics: Aminopropionitrile; Animals; Collagen; Disease Models, Animal; Fibrosis; Mice; Mice, Inbred mdx; Mus | 2022 |
Smooth Muscle Cell Relaxation Worsens Aortic Dilatation and Clinical Presentation in a BAPN/Angiotensin II-Induced Aortic Dissection Model in Rats.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Dilatation; Disease Models, Animal; | 2022 |
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice.
Topics: Aminopropionitrile; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; C | 2023 |
Smooth muscle angiotensin II type 1A receptor is required for abdominal aortic aneurysm formation induced by angiotensin II plus β-aminopropionitrile.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Hum | 2023 |
Low Zinc Alleviates the Progression of Thoracic Aortic Dissection by Inhibiting Inflammation.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease | 2023 |
Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice.
Topics: Allopurinol; Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Mode | 2023 |
Effects of Age, Sex, and Extracellular Matrix Integrity on Aortic Dilatation and Rupture in a Mouse Model of Marfan Syndrome.
Topics: Aminopropionitrile; Animals; Collagen; Dilatation; Disease Models, Animal; Extracellular Matrix; Fem | 2023 |
Gut Microbiota-Derived Tryptophan Metabolite Indole-3-aldehyde Ameliorates Aortic Dissection.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Models, Animal; G | 2023 |
High-frequency murine ultrasound provides enhanced metrics of BAPN-induced AAA growth.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Biomechanical Phenomena; | 2019 |
Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway
Topics: Acriflavine; ADAM17 Protein; Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease | 2019 |
Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis.
Topics: Aminopropionitrile; Animals; Collagen; Contracture; Disease Models, Animal; Fibrosis; Hydroxyproline | 2020 |
Female Mice Exhibit Abdominal Aortic Aneurysm Protection in an Established Rupture Model.
Topics: Administration, Oral; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm | 2020 |
Porcine Model of Infrarenal Abdominal Aortic Aneurysm.
Topics: Aminopropionitrile; Angioplasty, Balloon; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Col | 2019 |
IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Dissection; Apoptosis; Case-Control Studi | 2020 |
Induction of large cerebral aneurysms by intraperitoneal administration of β-aminopropionitrile fumarate in male rats.
Topics: Aminopropionitrile; Animals; Disease Models, Animal; Intracranial Aneurysm; Male; Rats; Rats, Spragu | 2022 |
Delayed Treatment With Low-intensity Extracorporeal Shock Wave Therapy in an Irreversible Rat Model of Stress Urinary Incontinence.
Topics: Aminopropionitrile; Animals; Deoxyuridine; Dilatation; Disease Models, Animal; Extracorporeal Shockw | 2020 |
Resveratrol Attenuates Aortic Dissection by Increasing Endothelial Barrier Function Through the SIRT1 Pathway.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm; Aortic Dissection; Ce | 2020 |
Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Aminopropionitrile; Aneurysm, Ruptured; Angiotensin II; Animals; | 2020 |
Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm.
Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneu | 2021 |
Therapeutic Effect of Rapamycin on Aortic Dissection in Mice.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Cell Cycle Checkpoints; Cell Line; D | 2020 |
Effects of Extracellular Matrix Softening on Vascular Smooth Muscle Cell Dysfunction.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cell Ded | 2020 |
Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model.
Topics: Aminopropionitrile; Animals; Antibodies; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2020 |
Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; At | 2020 |
A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs).
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Disease Mode | 2020 |
Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Diss | 2021 |
Arterial stiffness and cardiac dysfunction in Hutchinson-Gilford Progeria Syndrome corrected by inhibition of lysyl oxidase.
Topics: Aging, Premature; Aminopropionitrile; Animals; Disease Models, Animal; Female; Heart Diseases; Lamin | 2021 |
Authentication of In Situ Measurements for Thoracic Aortic Aneurysms in Mice.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Dilatation, Pathologic; Dis | 2021 |
Expression and role of lumican in acute aortic dissection: A human and mouse study.
Topics: Acute Disease; Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Dissection; Aortic Rupture | 2021 |
Biomechanical consequences of compromised elastic fiber integrity and matrix cross-linking on abdominal aortic aneurysmal enlargement.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; E | 2021 |
Bilateral superior cervical ganglionectomy attenuates the progression of β-aminopropionitrile-induced aortic dissection in rats.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Dissection; Arterial Pressure; Disease Models, Animal; Di | 2018 |
Crosslinking Enzyme Lysyl Oxidase Modulates Scleral Remodeling in Form-Deprivation Myopia.
Topics: Aminopropionitrile; Animals; Biomechanical Phenomena; Blotting, Western; Collagen Type I; Disease Mo | 2018 |
A novel reproducible model of aortic aneurysm rupture.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Rupture; Cytokines; Disease Models, Anima | 2018 |
Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism.
Topics: Aminopropionitrile; Animals; Cell Proliferation; Collagen Type I; Collagen Type III; Disease Models, | 2018 |
FAK-ERK activation in cell/matrix adhesion induced by the loss of apolipoprotein E stimulates the malignant progression of ovarian cancer.
Topics: Aminopropionitrile; Animals; Apolipoproteins E; Cell Adhesion; Cell Line, Tumor; Cell Transformation | 2018 |
Interleukin-3 stimulates matrix metalloproteinase 12 production from macrophages promoting thoracic aortic aneurysm/dissection.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cells, C | 2018 |
Postnatal deficiency of ADAMTS1 ameliorates thoracic aortic aneurysm and dissection in mice.
Topics: ADAMTS1 Protein; Aminopropionitrile; Animals; Aorta; Aortic Aneurysm, Thoracic; Aortic Dissection; D | 2018 |
Nitrosonifedipine, a Photodegradation Product of Nifedipine, Suppresses Pharmacologically Induced Aortic Aneurysm Formation.
Topics: Aminopropionitrile; Angiotensin II; Animals; Antigens, Differentiation; Antioxidants; Aortic Aneurys | 2018 |
Rapamycin prevents thoracic aortic aneurysm and dissection in mice.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aortic Aneurysm, Thoracic; A | 2019 |
A novel swine model of abdominal aortic aneurysm.
Topics: Aminopropionitrile; Angioplasty, Balloon; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Col | 2019 |
The Effect of Polydeoxyribonucleotide Extracted from Salmon Sperm on the Restoration of Bisphosphonate-Related Osteonecrosis of the Jaw.
Topics: Administration, Topical; Aminopropionitrile; Animals; Biological Products; Bisphosphonate-Associated | 2019 |
Increased aortic stiffness and attenuated lysyl oxidase activity in obesity.
Topics: Adipocytes; Adipose Tissue; Adult; Aminopropionitrile; Animals; Aorta, Abdominal; Case-Control Studi | 2013 |
Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic R | 2013 |
Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects.
Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aorta, Thor | 2013 |
Hypoxia-inducible factor 1-regulated lysyl oxidase is involved in Staphylococcus aureus abscess formation.
Topics: Abscess; Aminopropionitrile; Animals; Bacterial Load; Disease Models, Animal; Extracellular Matrix P | 2013 |
Increased 18F-FDG uptake is predictive of rupture in a novel rat abdominal aortic aneurysm rupture model.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Biomarker | 2015 |
Bone fracture toughness and strength correlate with collagen cross-link maturity in a dose-controlled lathyrism mouse model.
Topics: 3T3 Cells; Aminopropionitrile; Animals; Biomechanical Phenomena; Collagen; Disease Models, Animal; F | 2015 |
Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Ru | 2015 |
Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.
Topics: Acute Disease; Adventitia; Aged; Aminopropionitrile; Angiotensin II; Animals; Antibodies, Monoclonal | 2015 |
Mechanical stretch-induced endoplasmic reticulum stress, apoptosis and inflammation contribute to thoracic aortic aneurysm and dissection.
Topics: Activating Transcription Factor 4; Aminopropionitrile; Animals; Aorta; Aortic Aneurysm, Thoracic; Ap | 2015 |
Cardioprotective effects of lysyl oxidase inhibition against volume overload-induced extracellular matrix remodeling.
Topics: Aminopropionitrile; Animals; Arteriovenous Fistula; Cardiotonic Agents; Disease Models, Animal; Extr | 2016 |
KLF15 Overexpression Protects β-Aminopropionitrile-Induced Aortic Rupture in Rodent Model via Inhibiting Connective Tissue Growth Factor.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Aortic Rupture; Cells, Cultured; Collagen Type | 2017 |
β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice.
Topics: Actins; Aminopropionitrile; Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Blood Pressure; Body | 2016 |
Hypoxia-Inducible Factor-1α in Smooth Muscle Cells Protects Against Aortic Aneurysms-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abd | 2016 |
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Antineoplastic Agents; Apoptosis; Breast Ne | 2017 |
A novel chronic advanced stage abdominal aortic aneurysm murine model.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Chronic D | 2017 |
Ultrastructural and histomorphometric alterations of rat jaw bones after experimental induction of lathyrism.
Topics: Alveolar Process; Aminopropionitrile; Animals; Cell Count; Disease Models, Animal; Image Processing, | 2008 |
Effect of defective collagen synthesis on epithelial implant interface: lathyritic model in dogs. An experimental preliminary study.
Topics: Aminopropionitrile; Animals; Bone Density; Bone Remodeling; Collagen; Connective Tissue; Dental Impl | 2012 |
Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Angiotensin II; Animals; Animals, Newborn; Cardiomeg | 2012 |
Dramatic decrease of aortic longitudinal elastic strength in a rat model of aortic dissection.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic R | 2012 |
The role of lysyl oxidase family members in the stabilization of abdominal aortic aneurysms.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic An | 2012 |
[Biomechanical properties study of aorta in β-aminopropionitrile-induced rat model].
Topics: Aminopropionitrile; Animals; Aorta; Aortic Dissection; Biomechanical Phenomena; Disease Models, Anim | 2012 |
An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats.
Topics: Aminopropionitrile; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anim | 2002 |
Experimentally induced cerebral aneurysms in rats: Part VI. Hypertension.
Topics: Aminopropionitrile; Animals; Cerebral Arteries; Circle of Willis; Desoxycorticosterone; Disease Mode | 1980 |
The B-aminopropionitrile-fed turkey: a model for detecting potential drug action on arterial tissue.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Diseases; Disease Models, Ani | 1983 |
Inhibition of collagen cross-linking: a new approach to ocular scarring.
Topics: Aminopropionitrile; Animals; Cicatrix; Collagen; Conjunctiva; Disease Models, Animal; Rabbits; Wound | 1981 |
Experimentally induced cerebral aneurysms in rats: Part V. Relation of hemodynamics in the circle of Willis to formation of aneurysms.
Topics: Aminopropionitrile; Animals; Blood Pressure; Carotid Arteries; Carotid Artery Diseases; Circle of Wi | 1980 |
Experimental intracranial aneurysms in rats. A gross and microscopic study.
Topics: Aminopropionitrile; Animals; Carotid Arteries; Cerebral Arteries; Desoxycorticosterone; Disease Mode | 1980 |
Intrapulmonary gas mixing in panacinar- and centriacinar-induced emphysema in rats.
Topics: Administration, Inhalation; Administration, Oral; Aminopropionitrile; Animals; Breath Tests; Cadmium | 1998 |
Allylamine and beta-aminopropionitrile-induced vascular injury: enhanced expression of high-molecular-weight proteins.
Topics: Administration, Oral; Allylamine; Aminopropionitrile; Animals; Aorta; Collagen; Disease Models, Anim | 1998 |
Experimentally induced cerebral aneurysms in rats: part II.
Topics: Aminopropionitrile; Animals; Carotid Arteries; Desoxycorticosterone; Disease Models, Animal; Female; | 1979 |
[Experimental inducement of saccular cerebral aneurysms in rats (author's transl)].
Topics: Aminopropionitrile; Animals; Disease Models, Animal; Female; Hypertension; Intracranial Aneurysm; Li | 1979 |
[Chronic lathyrism, prolonged hyperlipidic diet, and atheroma in the rat].
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Arteriosclerosis; Chronic Disease; Diet, Atherogenic; | 1976 |
Galactosyl transferase assay. Application to experimental atherosclerosis.
Topics: Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Collagen; Diet, Atherogenic; Disease Models, A | 1976 |
Morphologic aspects of experimental esophageal lye strictures. II. Effect of steroid hormones, bougienage, and induced lathyrism on acute lye burns.
Topics: Adrenal Cortex Hormones; Aminopropionitrile; Animals; Burns, Chemical; Dilatation; Disease Models, A | 1977 |
Beta-aminopropionitrile as a radiation reaction preventive agent.
Topics: Aminopropionitrile; Animals; Collagen; Disease Models, Animal; Female; Humans; Hydroxyproline; Letha | 1976 |
Evaluation of drug treatments for proliferative vitreoretinopathy using vitreous microtensiometry.
Topics: Aminopropionitrile; Animals; Cattle; Disease Models, Animal; Drug Combinations; Equipment Design; Ev | 1991 |
Atherosclerosis mouse model induced by a high-cholesterol diet supplemented with beta-aminopropionitrile: effects of various anti-atherosclerotic agents on the biochemical parameters.
Topics: 4-Aminobenzoic Acid; Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Body Weight; Cholesterol; | 1990 |
Lathyrism: mini-review and a comment on the lack of effect of protease inhibitors on osteolathyrism.
Topics: Aminocaproates; Aminocaproic Acid; Aminopropionitrile; Animals; Aprotinin; Bone Diseases; Collagen; | 1985 |
The role of neutrophils in the development of cadmium chloride-induced emphysema in lathyrogen-fed hamsters.
Topics: Aminopropionitrile; Amitrole; Animals; Cadmium; Cadmium Chloride; Cricetinae; Disease Models, Animal | 1985 |
Nitrogen-dioxide-induced emphysema in rats. Lack of worsening by beta-aminopropionitrile treatment.
Topics: Aminopropionitrile; Analysis of Variance; Animals; Diet; Disease Models, Animal; Elastin; Germ-Free | 1988 |
Experimental induction of cerebral aneurysms in monkeys.
Topics: Aminopropionitrile; Animals; Carotid Arteries; Cerebral Angiography; Disease Models, Animal; Female; | 1987 |
[Reactivity of collagen and elastic fibers under various experimental conditons].
Topics: Aminopropionitrile; Animals; Collagen Diseases; Connective Tissue Cells; Disease Models, Animal; Ela | 1971 |
[Reactive pathological changes of the parenchyma in collagenosis induced by beta-aminopropionitrile].
Topics: Aminopropionitrile; Animals; Collagen Diseases; Disease Models, Animal; Glycosaminoglycans; Histolog | 1971 |
[Experimental clinical data on enterocyte activity in normal and pathological metabolism of connective tissue].
Topics: Administration, Oral; Aminopropionitrile; Animals; Collagen Diseases; Disease Models, Animal; Glycos | 1971 |
Pharmacology of fibrosis and tissue injury.
Topics: Aminopropionitrile; Animals; Asbestos; Collagen; Culture Techniques; Disease Models, Animal; Erythro | 1974 |
[Chronic lathyrism. Experimental model of the ageing of the connective tissue in man (author's transl)].
Topics: Aging; Aminopropionitrile; Animals; Aorta; Blood Vessels; Connective Tissue; Coronary Disease; Diabe | 1973 |
Use of large-molecular-weight compounds to produce local lathyrism in healing wounds.
Topics: Aminopropionitrile; Animals; Chick Embryo; Cicatrix; Disease Models, Animal; Lathyrism; Penicillamin | 1973 |
Production of arterial hemosiderosis in rhesus monkeys following the ingestion of -aminopropionitrile.
Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Arteries; Body Weight; Collagen; Disease Models, Anim | 1971 |
Liver regeneration and hepatic collagen deposition in rats with dimethjylnitrosamine-induced cirrhosis.
Topics: Aminopropionitrile; Animals; Collagen; Connective Tissue; Disease Models, Animal; Liver Cirrhosis, E | 1972 |
Dysostosis in adult rats after prolonged beta-aminopropionitrile feeding.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Autopsy; Body Weight; Diet; Disease Models, Ani | 1970 |