aminopropionitrile has been researched along with Cleft Palate in 15 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
Cleft Palate: Congenital fissure of the soft and/or hard palate, due to faulty fusion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cranial nerve palsy/paresis was only seen in HFM and thalidomide-induced malformations." | 1.30 | Teratological studies on craniofacial malformations. ( Jacobsson, C, 1997) |
| "Cleft palate was induced in 420 embryos of Sprague-Dawley rats with a single oral dose of 600 mg/kg beta-aminoproprionitrile (BAPN) on embryonal day 15, 7 hours." | 1.28 | Diagnosis of induced cleft palate in rats from defective patterns of differentiation of isoenzymes. ( Granström, G; Jacobsson, C; Kirkeby, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diewert, VM | 1 |
| Jacobsson, C | 3 |
| Granström, G | 2 |
| Burdi, AR | 1 |
| Mato, M | 1 |
| Uchiyama, Y | 1 |
| Aikawa, E | 1 |
| Smiley, GR | 1 |
| Kirkeby, S | 1 |
| Posner, HS | 1 |
| King, CT | 3 |
| Horigan, E | 1 |
| Wilk, AL | 2 |
| Pratt, RM | 1 |
| Barrow, MV | 2 |
| Steffek, AJ | 5 |
| Hendrickx, AG | 1 |
| Simpson, CF | 1 |
| Miller, EJ | 1 |
| Verrusio, AC | 1 |
| Watkins, CA | 1 |
| Horigan, EA | 1 |
| Stivers, FE | 1 |
| Yarington, CT | 1 |
2 reviews available for aminopropionitrile and Cleft Palate
| Article | Year |
|---|---|
Cleft lip and palate research: an updated state of the art. Section I. Epidemiology, etiology, and pathogenesis of cleft lip and palate.
Topics: Aminopropionitrile; Animals; Asian People; Chromosomes, Human; Cleft Lip; Cleft Palate; Collagen; En | 1977 |
Lathyrism: a review.
Topics: Abnormalities, Drug-Induced; Amino Acid Oxidoreductases; Aminopropionitrile; Aneurysm; Animals; Aort | 1974 |
13 other studies available for aminopropionitrile and Cleft Palate
| Article | Year |
|---|---|
Correlation between alterations in Meckel's cartilage and induction of cleft palate with beta-aminoproprionitrile in the rat.
Topics: Aminopropionitrile; Animals; Cleft Palate; Face; Female; Gestational Age; Pregnancy; Rats; Skull | 1981 |
Effects of vitamin B6 on beta-aminoproprionitrile-induced palatal cleft formation in the rat.
Topics: Administration, Oral; Aminopropionitrile; Animals; Cleft Palate; Diet; Drug Interactions; Female; Ge | 1997 |
Teratological studies on craniofacial malformations.
Topics: Alkaline Phosphatase; Aminopropionitrile; Amniotic Fluid; Animals; Branchial Region; Cartilage; Clef | 1997 |
Ultrastructural changes in rat palatal epithelium after beta-aminopropionitrile.
Topics: Aminopropionitrile; Animals; Animals, Newborn; Cell Nucleus; Cleft Palate; Desmosomes; Epithelium; F | 1975 |
Diagnosis of induced cleft palate in rats from defective patterns of differentiation of isoenzymes.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Amniotic Fluid; Animals; Cleft Palate; Clinical Enz | 1992 |
Significance of cleft palate induced by chemicals in the rat and mouse.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cleft Palate; Cortisone; Female; Mice; Nit | 1972 |
Fetal outcome from prolonged versus acute drug administration in the pregnant rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cleft Palate; Collagen; Demyelinating Dise | 1972 |
Inhibition of collagen cross-linking associated with beta-aminopropionitrile-induced cleft palate in the rat.
Topics: Administration, Oral; Aminopropionitrile; Animals; Cleft Palate; Collagen; Female; Gestational Age; | 1972 |
Teratologic and other embryotoxic effects of beta-aminopropionitrile in rats.
Topics: Abdominal Muscles; Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Body Weight; Bone and B | 1974 |
Lathyrogen-induced malformations in baboons: a preliminary report.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Bone and Bones; Cesarean Section; Cleft Pa | 1972 |
Cleft palate in rodents after maternal treatment with various lathyrogenic agents.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animal Feed; Animals; Cleft Palate; Female; Nitrile | 1972 |
Metabolism of -aminopropionitrile and its teratogenic activity in rats.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Aminopropionitrile; Animals; Carbon Isotopes; Cle | 1972 |
The effect of lathyrogens on developing midfacial structures in the rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cartilage; Cleft Palate; Diet; Face; Femal | 1971 |