aminopropionitrile has been researched along with Cicatrix in 26 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(1) No toxic signs or symptoms and no unusual laboratory determinations were observed in five patients with posterior urethral strictures treated by dilatation of the urethra and administration of 1 gm per day of beta-aminopropionitrile (BAPN) for twenty-one days." | 9.04 | Administration of beta-aminopropionitrile to human beings with urethral strictures: A prelimary report. ( Madden, JW; Peacock, EE, 1978) |
| "Beta-aminopropionitrile fumarate, an inhibitor of collagen cross-linking, was used topically in patients after filtration surgery for difficult cases of glaucoma (aphakic, repeat surgery, neovascular)." | 7.67 | Effects of beta-aminopropionitrile after glaucoma filtration surgery: pilot human trial. ( Kimbrough, R; Moorhead, LC; Smith, J; Stewart, R, 1987) |
| "(1) No toxic signs or symptoms and no unusual laboratory determinations were observed in five patients with posterior urethral strictures treated by dilatation of the urethra and administration of 1 gm per day of beta-aminopropionitrile (BAPN) for twenty-one days." | 5.04 | Administration of beta-aminopropionitrile to human beings with urethral strictures: A prelimary report. ( Madden, JW; Peacock, EE, 1978) |
| " The most advanced research involves prevention of the development of helical structure and transport of collagen by administration of proline analogues and controlled induction of lathyrism by administration of Beta-aminopropionitrile." | 4.75 | Pharmacological control of surgical scar tissue. ( Peacock, EE, 1978) |
| "Beta-aminopropionitrile fumarate, an inhibitor of collagen cross-linking, was used topically in patients after filtration surgery for difficult cases of glaucoma (aphakic, repeat surgery, neovascular)." | 3.67 | Effects of beta-aminopropionitrile after glaucoma filtration surgery: pilot human trial. ( Kimbrough, R; Moorhead, LC; Smith, J; Stewart, R, 1987) |
| " Ten patients with massive keloids, resistant to conventional therapy by excision, grafting, and/or intralesional injection of steroids, have been treated by excising the keloid, grafting the defect, inducing lathyrism with Beta aminopropionitrile fumurate or penicillamine and administering colchicine." | 3.66 | Pharmacologic control of surface scarring in human beings. ( Peacock, EE, 1981) |
| "Analysis of the area of scar and the intensity of stain was performed with Mocha image analysis software." | 1.30 | Pharmacologic inhibition of collagen in an experimental model of subglottic stenosis. ( Doolin, EJ; Santos, MC; Strande, LF; Tsuno, K, 1998) |
| "Pharmacologic inhibition of scar formation minimized distortion and contracture of intracardiac prosthetic patches and decreased adhesions." | 1.27 | Pharmacologic inhibition of scar contracture of intracardiac prosthetic patches. ( Doolin, EJ; Miginsky, MP; Moulton, AL; Richards, WO, 1984) |
| "In other situations, as in the treatment of keloids, physicians may wish to introduce drugs known to reduce scar formation into the biologic environment in which wound healing ensues." | 1.26 | Wound healing: a review. IV. Systemic medications affecting wound healing. ( Pollack, SV, 1982) |
| "Histological evaluation of the treated scar tissue was consistent with lathyrism." | 1.26 | Inhibition of collagen cross-linking: a new approach to ocular scarring. ( Moorhead, LC, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (96.15) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richards, WO | 1 |
| Doolin, EJ | 2 |
| Miginsky, MP | 1 |
| Moulton, AL | 1 |
| Pollack, SV | 1 |
| Peacock, EE | 12 |
| Moorhead, LC | 2 |
| Tsuno, K | 1 |
| Strande, LF | 1 |
| Santos, MC | 1 |
| Madden, JW | 2 |
| Jackson, DS | 1 |
| Labandter, H | 1 |
| Diegelmann, R | 1 |
| Cohen, IK | 2 |
| Arem, AJ | 1 |
| Rasmussen, D | 1 |
| Chvapil, M | 4 |
| Gibeault, JD | 1 |
| Cravens, RB | 1 |
| Camus, JP | 1 |
| Koeger, AC | 1 |
| Smith, J | 1 |
| Stewart, R | 1 |
| Kimbrough, R | 1 |
| Arem, A | 1 |
| Speer, DP | 2 |
| Feldman, S | 1 |
| Bora, FW | 1 |
| Lane, JM | 1 |
| Prockop, DJ | 1 |
| Brendel, K | 1 |
| Weiner, LJ | 1 |
| Davis, WM | 1 |
| Balis, JU | 1 |
| Chan, AS | 1 |
| Conen, PE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma[NCT00307606] | Phase 4 | 40 participants (Anticipated) | Interventional | 2005-12-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for aminopropionitrile and Cicatrix
| Article | Year |
|---|---|
Pharmacological control of surgical scar tissue.
Topics: Aminopropionitrile; Animals; Cicatrix; Colchicine; Collagen; Connective Tissue; Humans; Lathyrism; P | 1978 |
Possible modification of scar tissue by biochemical methods.
Topics: Aminopropionitrile; Animals; Cicatrix; Collagen; Cortisone; Humans; Hydroxylysine; Hydroxyproline; L | 1979 |
[D-penicillamine and collagen].
Topics: Aminopropionitrile; Arthritis, Rheumatoid; Autoantibodies; Bronchi; Cicatrix; Collagen; Collagen Dis | 1986 |
Collagen modifications.
Topics: Aminopropionitrile; Animals; Antigens; Biocompatible Materials; Biological Dressings; Cicatrix; Coll | 1985 |
Biology of wound repair.
Topics: Aminopropionitrile; Cicatrix; Collagen; Connective Tissue; Dactinomycin; Epithelium; Fibroblasts; Hu | 1973 |
Biologic principles affecting repair of flexor tendons.
Topics: Adult; Aminopropionitrile; Blood Vessels; Child, Preschool; Cicatrix; Collagen; Connective Tissue; C | 1971 |
1 trial available for aminopropionitrile and Cicatrix
| Article | Year |
|---|---|
Administration of beta-aminopropionitrile to human beings with urethral strictures: A prelimary report.
Topics: Aminopropionitrile; Cicatrix; Clinical Trials as Topic; Collagen; Drug Evaluation; Drug Hypersensiti | 1978 |
19 other studies available for aminopropionitrile and Cicatrix
| Article | Year |
|---|---|
Pharmacologic inhibition of scar contracture of intracardiac prosthetic patches.
Topics: Aminopropionitrile; Animals; Bioprosthesis; Blood Vessel Prosthesis; Cicatrix; Contracture; Dogs; He | 1984 |
Wound healing: a review. IV. Systemic medications affecting wound healing.
Topics: Adrenal Cortex Hormones; Aminopropionitrile; Animals; Anti-Inflammatory Agents; Anticoagulants; Anti | 1982 |
Pharmacologic control of surface scarring in human beings.
Topics: Adolescent; Adult; Aged; Aminopropionitrile; Child; Cicatrix; Colchicine; Drug Administration Schedu | 1981 |
Control of wound healing and scar formation in surgical patients.
Topics: Adolescent; Aminopropionitrile; Animals; Child; Cicatrix; Colchicine; Collagen; Dermatologic Surgica | 1981 |
Inhibition of collagen cross-linking: a new approach to ocular scarring.
Topics: Aminopropionitrile; Animals; Cicatrix; Collagen; Conjunctiva; Disease Models, Animal; Rabbits; Wound | 1981 |
Pharmacologic inhibition of collagen in an experimental model of subglottic stenosis.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Cicatrix; Collagen; Dexamethasone; Dogs; Glot | 1998 |
Some biologic and technical considerations in the repair of long tendons.
Topics: Aminopropionitrile; Animals; Cadaver; Cicatrix; Collagen; Connective Tissue; Dogs; Fingers; Foreign- | 1977 |
Potentiation of colchicine-induced collagenolysis.
Topics: Aminopropionitrile; Animals; Cicatrix; Colchicine; Collagen; Drug Therapy, Combination; Female; Prol | 1978 |
Monoamine oxidase inhibition during control of scar formation.
Topics: Aminopropionitrile; Animals; Cicatrix; Pargyline; Rats; Wound Healing | 1977 |
Pharmacology of fibrosis: definitions, limits and perspectives.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid Deficiency; Biopo | 1975 |
Transport of beta-aminopropionitrile through intact skin or scar tissue.
Topics: Absorption; Administration, Cutaneous; Aminopropionitrile; Animals; Carbon Radioisotopes; Cicatrix; | 1989 |
Effects of beta-aminopropionitrile after glaucoma filtration surgery: pilot human trial.
Topics: Administration, Topical; Adult; Aminopropionitrile; Cicatrix; Glaucoma; Humans; Intraocular Pressure | 1987 |
Can collagen metabolism be controlled: theoretical considerations.
Topics: Aminopropionitrile; Animals; Burns; Cicatrix; Collagen; Humans; Lysine; Proline; Wound Healing | 1985 |
The control of peritendinous adhesions using topical beta-aminopropionitrile base.
Topics: Administration, Topical; Aminopropionitrile; Animals; Biomechanical Phenomena; Chickens; Cicatrix; C | 1985 |
Inhibitors of collagen biosynthesis as a means of controlling scar formation in tendon injury.
Topics: Aminopropionitrile; Animals; Chelating Agents; Cicatrix; Collagen; Hindlimb; Hydroxyproline; Penicil | 1972 |
Use of large-molecular-weight compounds to produce local lathyrism in healing wounds.
Topics: Aminopropionitrile; Animals; Chick Embryo; Cicatrix; Disease Models, Animal; Lathyrism; Penicillamin | 1973 |
Prevention of esophageal stenosis with induced lathyrism.
Topics: Aminopropionitrile; Animals; Cicatrix; Collagen; Dogs; Esophageal Stenosis; Granulation Tissue; Lath | 1971 |
The effect of postlathyritic medial scar on the progression of experimental atherosclerosis in rats.
Topics: Aminopropionitrile; Animal Nutritional Physiological Phenomena; Animals; Aorta; Arteriosclerosis; Ba | 1968 |
Symposium on biological control of scar tissue.
Topics: Aminopropionitrile; Animals; Cicatrix; Collagen; Humans; Hydroxyproline; Nitriles; Penicillamine; Ri | 1968 |