Page last updated: 2024-10-21

aminopropionitrile and Breast Neoplasms

aminopropionitrile has been researched along with Breast Neoplasms in 6 studies

Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"Development of metastases was monitored by in vivo bioluminescence imaging, and tumor-induced osteolysis was assessed by micro-computed tomography (microCT)."5.35The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells. ( Ayres, F; Bondareva, A; Boyd, SK; Downey, CM; Hallgrimsson, B; Jirik, FR; Liu, W, 2009)
"Development of metastases was monitored by in vivo bioluminescence imaging, and tumor-induced osteolysis was assessed by micro-computed tomography (microCT)."1.35The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells. ( Ayres, F; Bondareva, A; Boyd, SK; Downey, CM; Hallgrimsson, B; Jirik, FR; Liu, W, 2009)
"Treatment of the invasive breast cancer cell lines, Hs578T and MDA-MB-231, with beta-aminopropionitrile (betaAPN), an irreversible inhibitor of LOX catalytic activity, leads to a significant decrease in cell motility/migration and adhesion formation."1.33Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism. ( Csiszar, K; Fogelgren, B; Fong, SF; Hendrix, MJ; Hess, AR; Kirschmann, DA; Payne, SL; Seftor, EA; Wiley, EL, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Zhu, S1
Zhang, T1
Gao, H1
Jin, G1
Yang, J1
He, X1
Guo, H1
Xu, F1
Chang, J1
Lucas, MC1
Leonte, LE1
Garcia-Montolio, M1
Singh, LB1
Findlay, AD1
Deodhar, M1
Foot, JS1
Jarolimek, W1
Timpson, P1
Erler, JT1
Cox, TR1
Bondareva, A1
Downey, CM1
Ayres, F1
Liu, W1
Boyd, SK1
Hallgrimsson, B1
Jirik, FR1
Barry-Hamilton, V1
Spangler, R1
Marshall, D1
McCauley, S1
Rodriguez, HM1
Oyasu, M1
Mikels, A1
Vaysberg, M1
Ghermazien, H1
Wai, C1
Garcia, CA1
Velayo, AC1
Jorgensen, B1
Biermann, D1
Tsai, D1
Green, J1
Zaffryar-Eilot, S1
Holzer, A1
Ogg, S1
Thai, D1
Neufeld, G1
Van Vlasselaer, P1
Smith, V1
Kirschmann, DA2
Seftor, EA2
Fong, SF2
Nieva, DR1
Sullivan, CM1
Edwards, EM1
Sommer, P1
Csiszar, K2
Hendrix, MJ2
Payne, SL1
Fogelgren, B1
Hess, AR1
Wiley, EL1

Other Studies

6 other studies available for aminopropionitrile and Breast Neoplasms

ArticleYear
Combination Therapy of Lox Inhibitor and Stimuli-Responsive Drug for Mechanochemically Synergistic Breast Cancer Treatment.
    Advanced healthcare materials, 2023, Volume: 12, Issue:21

    Topics: Aminopropionitrile; Breast Neoplasms; Collagen; Extracellular Matrix; Female; Humans; Quinones; Tumo

2023
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.
    Oncotarget, 2017, Apr-18, Volume: 8, Issue:16

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Antineoplastic Agents; Apoptosis; Breast Ne

2017
The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells.
    PloS one, 2009, Volume: 4, Issue:5

    Topics: Aminopropionitrile; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Prolife

2009
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment.
    Nature medicine, 2010, Volume: 16, Issue:9

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Antibodies, Monoclonal; Breast Neoplasms; C

2010
A molecular role for lysyl oxidase in breast cancer invasion.
    Cancer research, 2002, Aug-01, Volume: 62, Issue:15

    Topics: Aminopropionitrile; Breast Neoplasms; Enzyme Inhibitors; Humans; Isoenzymes; Neoplasm Invasiveness;

2002
Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism.
    Cancer research, 2005, Dec-15, Volume: 65, Issue:24

    Topics: Aminopropionitrile; Breast Neoplasms; Catalase; Cell Adhesion; Cell Movement; Enzyme Activation; Fem

2005