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aminopropionitrile and Body Weight

aminopropionitrile has been researched along with Body Weight in 36 studies

Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" β-Aminopropionitrile (BAPN), an inhibitor of LOX activity, significantly attenuated the increase in body weight and cardiac hypertrophy observed in HFD rats."7.83The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats. ( Bartolomé, MV; Cachofeiro, V; Galán, M; Islas, F; Jurado-López, R; López-Andrés, N; Luaces, M; Martínez-González, J; Martínez-Martínez, E; Miana, M; Rodríguez, C, 2016)
"We have developed a model of aortic smooth muscle necrosis in adult Sprague Dawley rats by feeding them two vascular toxins (allylamine HCl, or AA, and beta-aminopropionitrile, or betaAPN) in concert for 10 days."7.70Allylamine and beta-aminopropionitrile induced aortic medial necrosis: mechanisms of synergism. ( Boor, PJ; Kumar, D; Trent, MB, 1998)
"beta-Aminopropionitrile (beta APN), an agent that prevents collagen accumulation in tissues, was evaluated for its ability to prevent excess collagen formation in bleomycin-induced pulmonary fibrosis in the hamster."7.66beta-Aminopropionitrile prevents bleomycin-induced pulmonary fibrosis in the hamster. ( Berg, RA; Edelman, NH; Ianni, BD; Kerr, JS; Pietra, GG; Prockop, DJ; Riley, DJ, 1982)
" β-Aminopropionitrile (BAPN), an inhibitor of LOX activity, significantly attenuated the increase in body weight and cardiac hypertrophy observed in HFD rats."3.83The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats. ( Bartolomé, MV; Cachofeiro, V; Galán, M; Islas, F; Jurado-López, R; López-Andrés, N; Luaces, M; Martínez-González, J; Martínez-Martínez, E; Miana, M; Rodríguez, C, 2016)
"We have developed a model of aortic smooth muscle necrosis in adult Sprague Dawley rats by feeding them two vascular toxins (allylamine HCl, or AA, and beta-aminopropionitrile, or betaAPN) in concert for 10 days."3.70Allylamine and beta-aminopropionitrile induced aortic medial necrosis: mechanisms of synergism. ( Boor, PJ; Kumar, D; Trent, MB, 1998)
"We tested the efficacy of 2 antifibrotic agents, the proline analogue cis-4-hydroxy-L-proline (cHyp) and the lathyrogen beta-aminopropionitrile (BAPN), on experimental silicosis in hamsters."3.67Treatment of experimental silicosis with antifibrotic agents. ( Geismar, LS; Kerr, JS; Riley, DJ; Trelstad, RL, 1988)
"Phenytoin has a beneficial effect on wound healing and on the healing of bone fractures, while beta-aminopropionitrile (BAPN) has an adverse effect on both."3.67Effect of phenytoin and/or beta-aminoproprionitrile on a surgically induced periosteal wound. ( Kuebel, MA; Taylor, JJ; Yeager, VL, 1985)
"beta-Aminopropionitrile (beta APN), an agent that prevents collagen accumulation in tissues, was evaluated for its ability to prevent excess collagen formation in bleomycin-induced pulmonary fibrosis in the hamster."3.66beta-Aminopropionitrile prevents bleomycin-induced pulmonary fibrosis in the hamster. ( Berg, RA; Edelman, NH; Ianni, BD; Kerr, JS; Pietra, GG; Prockop, DJ; Riley, DJ, 1982)
"To investigate a putative role for semicarbazide-sensitive amine oxidase (SSAO) in arterial extracellular matrix (ECM) organization, we compared arteries of growing Brown Norway (BN) rats after chronic administration of semicarbazide (SCZ) and beta-aminopropionitrile (BAPN), two inhibitors with different properties and relative specificities for SSAO and lysyl oxidase (LOX)."1.35Comparison of the effects of semicarbazide and beta-aminopropionitrile on the arterial extracellular matrix in the Brown Norway rat. ( Challande, P; Kakou, A; Lacolley, P; Mercier, N; Osborne-Pellegrin, M, 2009)
"Thus, in pressure-overloaded cardiac hypertrophy with coronary hypertension, coronary reserve seems to be determined by medial hypertrophy independently of collagen deposition, but collagen deposition plays an important role in the reversal of vasodilator reserve after relief of the overload."1.28Collagen deposition and the reversal of coronary reserve in cardiac hypertrophy. ( Isoyama, S; Ito, N; Satoh, K; Takishima, T, 1992)
" Commercially available DMAPN metabolites, administered by gavage, produced toxic effects less adverse than DMAPN."1.28Studies on the mechanism of urotoxic effects of N,N'-dimethylaminopropionitrile in rats and mice. 1. Biochemical and morphologic characterization of the injury and its relationship to metabolism. ( Ahmed, AE; Farooqui, MY; Frankenberg, L; Ghanayem, BI; Mumtaz, MM; Rajaraman, S, 1991)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199025 (69.44)18.7374
1990's7 (19.44)18.2507
2000's1 (2.78)29.6817
2010's3 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ida, T1
Kaku, M1
Kitami, M1
Terajima, M1
Rosales Rocabado, JM1
Akiba, Y1
Nagasawa, M1
Yamauchi, M1
Uoshima, K1
Martínez-Martínez, E1
Rodríguez, C1
Galán, M1
Miana, M1
Jurado-López, R1
Bartolomé, MV1
Luaces, M1
Islas, F1
Martínez-González, J1
López-Andrés, N1
Cachofeiro, V1
Ren, W1
Liu, Y1
Wang, X1
Jia, L1
Piao, C1
Lan, F1
Du, J1
Mercier, N1
Kakou, A1
Challande, P1
Lacolley, P1
Osborne-Pellegrin, M1
Kohn, RR1
Leash, AM1
Riley, DJ4
Kerr, JS4
Berg, RA2
Ianni, BD1
Pietra, GG1
Edelman, NH1
Prockop, DJ1
Frank, MM1
Trelstad, RL2
Frankel, HM1
Hoffman, DL1
Owen, JA1
Chvapil, M1
Chang, K1
Uitto, J1
Rowold, EA1
Grant, GA1
Kilo, C1
Williamson, JR1
Taverne, AA1
Kumar, D2
Trent, MB1
Boor, PJ2
Bing, OH1
Fanburg, BL1
Brooks, WW1
Matsushita, S1
Gibson, KD1
Segen, BJ1
Doller, HJ1
LaBella, F1
Vivian, S2
Ogawa, M1
Ozaki, M1
LaBella, FS1
Isoyama, S1
Ito, N1
Satoh, K1
Takishima, T1
Nakashima, Y1
Sueishi, K1
Mumtaz, MM1
Farooqui, MY1
Ghanayem, BI1
Rajaraman, S1
Frankenberg, L1
Ahmed, AE1
Yamaguchi, Y1
Yamada, K1
Kitagawa, S1
Kunitomo, M1
Hysmith, RM1
Ohshima, S1
Nakamura, G1
Chiba, M1
Geismar, LS1
Cox, RH1
Bashey, R1
Jimenez, S1
Kramer, MJ1
Chae, CU1
Yu, SY1
Kuebel, MA1
Yeager, VL1
Taylor, JJ1
Bar, A1
Hurwitz, S1
Barrow, MV1
Steffek, AJ1
Tipton, CM1
Matthes, RD1
Sandage, DS1
Saedi, S1
Nyhus, LM1
Gabrys, BF1
Kusakari, K1
Bombeck, CT1
Lalich, JJ2
Paik, WC1
Allen, JR1
Hall, BK1
Krista, LM1
Waibel, PE1
Sautter, JH1
Shoffner, RN1
Angevine, DM1
Balis, JU1
Chan, AS1
Conen, PE1
Levene, CI1
Bye, I1
Saffiotti, U1

Other Studies

36 other studies available for aminopropionitrile and Body Weight

ArticleYear
Extracellular matrix with defective collagen cross-linking affects the differentiation of bone cells.
    PloS one, 2018, Volume: 13, Issue:9

    Topics: 3T3 Cells; Aminopropionitrile; Animals; Body Weight; Cell Differentiation; Collagen Type I; Dose-Res

2018
The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats.
    Journal of molecular and cellular cardiology, 2016, Volume: 92

    Topics: Aminopropionitrile; Animals; Aorta; Blood Pressure; Body Weight; Diet, High-Fat; Extracellular Matri

2016
β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice.
    Scientific reports, 2016, 06-22, Volume: 6

    Topics: Actins; Aminopropionitrile; Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Blood Pressure; Body

2016
Comparison of the effects of semicarbazide and beta-aminopropionitrile on the arterial extracellular matrix in the Brown Norway rat.
    Toxicology and applied pharmacology, 2009, Sep-15, Volume: 239, Issue:3

    Topics: Amine Oxidase (Copper-Containing); Aminopropionitrile; Animals; Aorta, Thoracic; Body Weight; Caroti

2009
Long-term lathyrogen administration to rats, with special reference to aging.
    Experimental and molecular pathology, 1967, Volume: 7, Issue:3

    Topics: Aging; Aminopropionitrile; Animals; Body Weight; Female; Growth; Lathyrism; Longevity; Male; Nitrile

1967
beta-Aminopropionitrile prevents bleomycin-induced pulmonary fibrosis in the hamster.
    The American review of respiratory disease, 1982, Volume: 125, Issue:1

    Topics: Aminopropionitrile; Animals; Bleomycin; Body Weight; Collagen; Cricetinae; Lung; Lung Volume Measure

1982
Reduction of chronic hypoxic pulmonary hypertension in the rat by beta-aminopropionitrile.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 57, Issue:6

    Topics: Aminopropionitrile; Animals; Body Weight; Chronic Disease; Heart Ventricles; Hematocrit; Hemodynamic

1984
Healing of skin incision wounds treated with topically applied BAPN free base in the rat.
    Experimental and molecular pathology, 1983, Volume: 39, Issue:2

    Topics: Administration, Topical; Aminopropionitrile; Animals; Body Weight; Collagen; Dose-Response Relations

1983
Increased collagen cross-linkages in experimental diabetes: reversal by beta-aminopropionitrile and D-penicillamine.
    Diabetes, 1980, Volume: 29, Issue:10

    Topics: Amino Acids; Aminopropionitrile; Animals; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, E

1980
Collagen responsible for tooth eruption? A study of the eruption of rat incisors.
    Australian orthodontic journal, 1993, Volume: 12, Issue:4

    Topics: Aminoacetonitrile; Aminopropionitrile; Animals; Body Weight; Collagen; Female; Lathyrism; Penicillam

1993
Allylamine and beta-aminopropionitrile induced aortic medial necrosis: mechanisms of synergism.
    Toxicology, 1998, Feb-06, Volume: 125, Issue:2-3

    Topics: Allylamine; Aminopropionitrile; Analysis of Variance; Animals; Aorta; Body Weight; Diet; Drug Synerg

1998
The effect of lathyrogen beta-amino proprionitrile (BAPN) on the mechanical properties of experimentally hypertrophied rat cardiac muscle.
    Circulation research, 1978, Volume: 43, Issue:4

    Topics: Aminopropionitrile; Animals; Body Weight; Cardiomegaly; Heart Ventricles; Hydroxyproline; Male; Myoc

1978
Changes in chemical composition of chick embryos treated with a beta-xyloside and a lathyrogen.
    Teratology, 1979, Volume: 19, Issue:3

    Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Body Weight; Chick Embryo; Chondroitin Sul

1979
Beta-aminopropiontrile promotes longevity in mice.
    Experimental gerontology, 1978, Volume: 13, Issue:3-4

    Topics: Aging; Aminopropionitrile; Animals; Body Weight; Longevity; Male; Mice

1978
Inhibitory effect of beta-aminopropionitrile on the development of hypertension in spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1978, Volume: 28, Issue:5

    Topics: Aminopropionitrile; Animals; Body Weight; Collagen; Hypertension; Male; Norepinephrine; Rats; Time F

1978
Effect of beta-aminopropionitrile or prednisolone on survival of male LAF/J mice.
    Experimental gerontology, 1975, Volume: 10, Issue:3-4

    Topics: Aminopropionitrile; Animals; Body Weight; Life Expectancy; Longevity; Male; Mice; Prednisolone

1975
Collagen deposition and the reversal of coronary reserve in cardiac hypertrophy.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 20, Issue:4

    Topics: Aminopropionitrile; Animals; Arteries; Blood Flow Velocity; Blood Pressure; Body Weight; Carbon Diox

1992
Alteration of elastic architecture in the lathyritic rat aorta implies the pathogenesis of aortic dissecting aneurysm.
    The American journal of pathology, 1992, Volume: 140, Issue:4

    Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Body Weight;

1992
Studies on the mechanism of urotoxic effects of N,N'-dimethylaminopropionitrile in rats and mice. 1. Biochemical and morphologic characterization of the injury and its relationship to metabolism.
    Journal of toxicology and environmental health, 1991, Volume: 33, Issue:1

    Topics: Aminopropionitrile; Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Dose-Response Relationshi

1991
Atherosclerosis mouse model induced by a high-cholesterol diet supplemented with beta-aminopropionitrile: effects of various anti-atherosclerotic agents on the biochemical parameters.
    Japanese journal of pharmacology, 1990, Volume: 54, Issue:2

    Topics: 4-Aminobenzoic Acid; Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Body Weight; Cholesterol;

1990
Allylamine and beta-aminopropionitrile-induced vascular injury: an in vivo and in vitro study.
    Toxicology and applied pharmacology, 1990, Volume: 103, Issue:2

    Topics: Allylamine; Amines; Aminopropionitrile; Animals; Aorta; Body Weight; Cells, Cultured; Dose-Response

1990
Effects of lathyrogens on the mechanical strength of the periodontal ligament in the rat mandibular first molar.
    Journal of periodontal research, 1989, Volume: 24, Issue:5

    Topics: Acetonitriles; Aminoacetonitrile; Aminopropionitrile; Animals; Body Weight; Cysteamine; Dose-Respons

1989
Treatment of experimental silicosis with antifibrotic agents.
    Toxicology, 1988, Dec-30, Volume: 53, Issue:2-3

    Topics: Aminopropionitrile; Animals; Body Weight; Bone and Bones; Cricetinae; Hydroxyproline; Lung; Male; Me

1988
Effects of chronic beta-aminoproprionitrile treatment on rat carotid artery.
    Blood vessels, 1988, Volume: 25, Issue:2

    Topics: Administration, Oral; Aminopropionitrile; Animals; Blood Pressure; Body Weight; Carotid Arteries; Co

1988
Damage and repair of lung connective tissue in rats exposed to toxic levels of oxygen.
    The American review of respiratory disease, 1987, Volume: 135, Issue:2

    Topics: Aging; Aminopropionitrile; Animals; Biomechanical Phenomena; Body Weight; Bronchi; Collagen; Connect

1987
Effect of phenytoin and/or beta-aminoproprionitrile on a surgically induced periosteal wound.
    Journal of experimental pathology, 1985,Summer, Volume: 2, Issue:2

    Topics: Administration, Oral; Aminopropionitrile; Animals; Body Weight; Cartilage; Fractures, Bone; Male; Pe

1985
Bone ash, duodenal 45Ca absorption and calcium-binding protein in chicks fed lathyrogens.
    Comparative biochemistry and physiology. A, Comparative physiology, 1974, Apr-01, Volume: 47, Issue:4

    Topics: Aminopropionitrile; Animals; Body Weight; Bone and Bones; Calcium; Calcium Radioisotopes; Chickens;

1974
Teratologic and other embryotoxic effects of beta-aminopropionitrile in rats.
    Teratology, 1974, Volume: 10, Issue:2

    Topics: Abdominal Muscles; Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Body Weight; Bone and B

1974
In situ measurement of junction strength and ligament elongation in rats.
    Journal of applied physiology, 1974, Volume: 37, Issue:5

    Topics: Aminopropionitrile; Animals; Body Weight; Elasticity; Female; Femoral Artery; Femur; Hypophysectomy;

1974
Pharmacological prevention of esophageal stricture: an experimental study in the cat.
    The American surgeon, 1973, Volume: 39, Issue:8

    Topics: Aminopropionitrile; Animals; Body Weight; Burns, Chemical; Cats; Esophageal Stenosis; Esophagoscopy;

1973
Production of arterial hemosiderosis in rhesus monkeys following the ingestion of -aminopropionitrile.
    Laboratory investigation; a journal of technical methods and pathology, 1971, Volume: 25, Issue:4

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Arteries; Body Weight; Collagen; Disease Models, Anim

1971
Skeletal defects in embryonic chicks induced by administration of beta-aminopropionitrile.
    Teratology, 1972, Volume: 5, Issue:1

    Topics: Abnormalities, Drug-Induced; Alkaline Phosphatase; Aminopropionitrile; Animals; Body Weight; Bone an

1972
Aortic rupture, body weight, and blood pressure in the turkey as influenced by strain, dietary fat, beta-aminopropionitrile fumarate, and diethylstilbestrol.
    Poultry science, 1969, Volume: 48, Issue:6

    Topics: Aminopropionitrile; Animals; Aortic Rupture; Blood Pressure; Body Weight; Dietary Fats; Diethylstilb

1969
Dysostosis in adult rats after prolonged beta-aminopropionitrile feeding.
    Archives of pathology, 1970, Volume: 90, Issue:1

    Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Autopsy; Body Weight; Diet; Disease Models, Ani

1970
The effect of postlathyritic medial scar on the progression of experimental atherosclerosis in rats.
    Experimental and molecular pathology, 1968, Volume: 8, Issue:1

    Topics: Aminopropionitrile; Animal Nutritional Physiological Phenomena; Animals; Aorta; Arteriosclerosis; Ba

1968
The effect of beta-aminopropionitrile on silicotic pulmonary fibrosis in the rat.
    British journal of experimental pathology, 1968, Volume: 49, Issue:2

    Topics: Aminopropionitrile; Animals; Body Weight; Collagen; Female; Lung; Male; Nitriles; Organ Size; Pulmon

1968