aminopropionitrile has been researched along with Aortic Dissection in 44 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Angiotensin II (AngII) has been widely used to promotes aortic dissections in mice." | 8.12 | Smooth Muscle Cell Relaxation Worsens Aortic Dilatation and Clinical Presentation in a BAPN/Angiotensin II-Induced Aortic Dissection Model in Rats. ( Darmon, A; Dupont, S; El Bitar, S; Jondeau, G; Michel, JB; Pellenc, Q, 2022) |
| "Given the controversy regarding the appropriate dose of β-aminopropionitrile for induction of aortic dissection models in rats, the purpose of this study was to explore the most suitable concentration of β-aminopropionitrile to establish a high-incidence and low-mortality aortic dissection model." | 8.02 | Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats. ( Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X, 2021) |
| " The model was established by administering angiotensin II (Ang II) and β-aminopropionitrile (BAPN), a lysyl oxidase inhibitor, to mice to induce hypertension and degeneration of the elastic lamina, which would eventually result in the onset of an aortic aneurysm." | 7.96 | Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice. ( Chuma, M; Goda, M; Hosooka, M; Ishizawa, K; Izawa-Ishizawa, Y; Kagimoto, Y; Kondo, M; Matsuoka, R; Saito, N; Takechi, K; Tsuneyama, K; Yagi, K; Zamami, Y, 2020) |
| "This study compared three β-aminopropionitrile (BAPN) treatment rats to find the optimal BAPN model for thoracic aortic dissection and aneurysm in one study." | 7.79 | Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage. ( Jing, ZP; Li, HY; Li, JS; Wang, L; Zhang, L, 2013) |
| "25% beta-aminopropionitrile monofumarate (BAPN)-induced aortic dissection and histopathologic findings in a rat model." | 7.71 | An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats. ( Aoka, Y; Aomi, S; Hagiwara, N; Kasanuki, H; Kawana, M; Nagashima, H; Sakomura, Y; Sakuta, A; Uto, K, 2002) |
| "Thoracic aortic dissection (TAD) is a life-threatening disease that is characterized by an inflammatory response." | 5.51 | Involvement of B cells in the pathophysiology of β-aminopropionitrile-induced thoracic aortic dissection in mice. ( Gao, Y; Guo, J; Pan, L; Sun, W; Tu, Y; Wang, Z; Yang, Z; Yu, C; Zhao, J; Zheng, J, 2019) |
| "This study uncovered an important and previously unrecognized role of hyperuricemia in mediating the pathogenesis of TAAD, and uric acid-lowering drug may represent a promising therapeutic approach for TAAD." | 4.31 | Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice. ( Cai, Z; Dai, R; Fu, Y; Gong, Z; Kong, W; Li, W; Li, Z; Luo, C; Shen, Y; Wang, J; Wu, H; Yang, L; Yu, F; Zhang, T; Zhang, X; Zhao, H; Zhao, Y; Zhu, J, 2023) |
| " Angiotensin II (AngII) has been widely used to promotes aortic dissections in mice." | 4.12 | Smooth Muscle Cell Relaxation Worsens Aortic Dilatation and Clinical Presentation in a BAPN/Angiotensin II-Induced Aortic Dissection Model in Rats. ( Darmon, A; Dupont, S; El Bitar, S; Jondeau, G; Michel, JB; Pellenc, Q, 2022) |
| "Given the controversy regarding the appropriate dose of β-aminopropionitrile for induction of aortic dissection models in rats, the purpose of this study was to explore the most suitable concentration of β-aminopropionitrile to establish a high-incidence and low-mortality aortic dissection model." | 4.02 | Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats. ( Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X, 2021) |
| " The model was established by administering angiotensin II (Ang II) and β-aminopropionitrile (BAPN), a lysyl oxidase inhibitor, to mice to induce hypertension and degeneration of the elastic lamina, which would eventually result in the onset of an aortic aneurysm." | 3.96 | Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice. ( Chuma, M; Goda, M; Hosooka, M; Ishizawa, K; Izawa-Ishizawa, Y; Kagimoto, Y; Kondo, M; Matsuoka, R; Saito, N; Takechi, K; Tsuneyama, K; Yagi, K; Zamami, Y, 2020) |
| " Using an aortic dissection model in SR-A1-deficient mice and their wild type littermates, we found that SR-A1 deficiency aggravated beta-aminopropionitrile monofumarate induced thoracic aortic dilation, false lumen formation, extracellular matrix degradation, vascular inflammation and accumulation of apoptotic cells." | 3.91 | Scavenger receptor A1 attenuates aortic dissection via promoting efferocytosis in macrophages. ( Bai, H; Ben, J; Chen, Q; Chen, S; Huang, J; Jiang, Y; Li, X; Yang, Q; Zhang, H; Zhang, Z; Zhou, W; Zhou, Z; Zhu, X, 2019) |
| "This study compared three β-aminopropionitrile (BAPN) treatment rats to find the optimal BAPN model for thoracic aortic dissection and aneurysm in one study." | 3.79 | Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage. ( Jing, ZP; Li, HY; Li, JS; Wang, L; Zhang, L, 2013) |
| "To investigate thoracic aortic longitudinal elastic strength in β-aminopropionitrile (BAPN) treated rat model of aortic dissection (AD)." | 3.78 | [Biomechanical properties study of aorta in β-aminopropionitrile-induced rat model]. ( Bao, JM; Jing, ZP; Lin, C; Lu, H; Lu, QS; Wang, L; Zhang, L, 2012) |
| "25% beta-aminopropionitrile monofumarate (BAPN)-induced aortic dissection and histopathologic findings in a rat model." | 3.71 | An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats. ( Aoka, Y; Aomi, S; Hagiwara, N; Kasanuki, H; Kawana, M; Nagashima, H; Sakomura, Y; Sakuta, A; Uto, K, 2002) |
| "β-aminopropionitrile monofumarate was administrated in mice to induce TAD." | 1.91 | Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice. ( Chen, D; Chen, Q; Cutillas, PR; Li, D; Liu, C; Luo, J; Niu, K; Pearce, SWA; Shao, Y; Wu, Q; Xiao, Q; Yang, M; Yang, Z; Zhang, C; Zhang, L; Zhao, L; Zhou, X, 2023) |
| "Combination of METH and BAPN caused thoracic aortic aneurysm/dissection in 60% of rats." | 1.72 | Methamphetamine induces thoracic aortic aneurysm/dissection through C/EBPβ. ( Cai, DP; Chen, SY; Guo, D; Luo, BY; Tian, Q; Wang, HJ; Xie, WB; Xu, ZZ; Yang, Q; Zhou, J; Zhou, RM, 2022) |
| "The incidence and mortality of aortic dissection (AD) are increasing." | 1.72 | ALDH ( Cui, Y; Liu, Z; Luo, C; Wang, S; Zhou, B, 2022) |
| "However, the role of IL-5 in acute aortic dissection (AAD) has barely been explored." | 1.56 | IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis. ( Ren, Q; Ren, W; Ruan, Y; Wang, J; Wang, Z; Wu, Z; Yu, A, 2020) |
| "Thoracic aortic dissection (TAD) is associated with matrix changes, biochemical changes, and inflammatory markers like interleukin-1 beta (IL-1β)." | 1.56 | Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model. ( Chu, YX; Guo, LL; Jing, ZP; Li, JS; Sun, YD; Tian, P; Wu, MT; Yeung, KK; Zhang, L; Zhang, LW, 2020) |
| "The hallmarks of aortic dissection comprise aortic inflammatory cell infiltration and elastic fiber disruption, highlighting the involvement of macrophage." | 1.51 | Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway ( Jiang, C; Kong, W; Li, X; Lian, G; Liu, H; Pang, Y; Sun, L; Wang, X; Zhang, L; Zhang, T; Zhang, X; Zhang, Y, 2019) |
| "Thoracic aortic dissection (TAD) is an aggressive and life-threatening vascular disease and there is no effective means of early diagnosis of dissection." | 1.48 | Identification of type IV collagen exposure as a molecular imaging target for early detection of thoracic aortic dissection. ( Du, J; Jia, L; Li, P; Li, Y; Qi, F; Xu, C; Xu, FJ; Xu, K; Yu, B; Zhang, Y, 2018) |
| "Acute aortic dissection is one of the most lethal cardiovascular disease." | 1.48 | CD40L promotes development of acute aortic dissection via induction of inflammation and impairment of endothelial cell function. ( Dai, L; Han, L; Jiang, WJ; Lan, F; Li, HY; Liu, O; Zhang, HJ; Zhao, YF, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.82) | 18.7374 |
| 1990's | 1 (2.27) | 18.2507 |
| 2000's | 1 (2.27) | 29.6817 |
| 2010's | 15 (34.09) | 24.3611 |
| 2020's | 24 (54.55) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, S | 2 |
| Liu, Z | 3 |
| Xie, N | 2 |
| Huang, C | 1 |
| Li, Z | 5 |
| Yu, F | 3 |
| Fu, Y | 6 |
| Cui, Q | 1 |
| Kong, W | 7 |
| Luo, BY | 1 |
| Zhou, J | 1 |
| Guo, D | 1 |
| Yang, Q | 2 |
| Tian, Q | 1 |
| Cai, DP | 1 |
| Zhou, RM | 1 |
| Xu, ZZ | 1 |
| Wang, HJ | 1 |
| Chen, SY | 1 |
| Xie, WB | 1 |
| Luo, C | 3 |
| Zhou, B | 2 |
| Cui, Y | 1 |
| Wang, S | 2 |
| Zhang, C | 4 |
| Niu, K | 2 |
| Ren, M | 1 |
| Zhou, X | 2 |
| Yang, Z | 3 |
| Yang, M | 2 |
| Wang, X | 3 |
| Luo, J | 3 |
| Shao, Y | 4 |
| Chen, D | 3 |
| Gao, S | 1 |
| Ge, S | 1 |
| Wu, Q | 2 |
| Xiao, Q | 2 |
| Xie, Y | 1 |
| Gao, R | 1 |
| Gao, Y | 3 |
| Dong, Z | 2 |
| Ge, J | 2 |
| Pellenc, Q | 1 |
| El Bitar, S | 1 |
| Darmon, A | 1 |
| Dupont, S | 1 |
| Michel, JB | 1 |
| Jondeau, G | 1 |
| Yang, YY | 2 |
| Jiao, XL | 2 |
| Yu, HH | 2 |
| Li, LY | 2 |
| Li, J | 2 |
| Zhang, XP | 2 |
| Qin, YW | 2 |
| Yang, X | 2 |
| Xu, C | 2 |
| Yao, F | 1 |
| Ding, Q | 1 |
| Liu, H | 4 |
| Wang, D | 2 |
| Huang, J | 3 |
| Shen, Y | 2 |
| Yang, W | 1 |
| Wang, L | 4 |
| Ma, Q | 2 |
| Zhu, J | 2 |
| Xu, F | 1 |
| Cong, X | 1 |
| Gong, Z | 3 |
| Yang, S | 1 |
| Ma, Z | 1 |
| Zhu, L | 1 |
| An, P | 1 |
| Zhao, W | 1 |
| Xia, Y | 1 |
| Qi, J | 1 |
| Luo, Y | 1 |
| Yang, L | 1 |
| Wu, H | 1 |
| Zhao, Y | 1 |
| Dai, R | 2 |
| Zhang, X | 5 |
| Cai, Z | 1 |
| Li, W | 2 |
| Zhao, H | 1 |
| Zhang, T | 2 |
| Wang, J | 2 |
| Pearce, SWA | 1 |
| Chen, Q | 2 |
| Liu, C | 2 |
| Li, D | 2 |
| Cutillas, PR | 1 |
| Zhao, L | 1 |
| Zhang, L | 7 |
| Huang, SS | 1 |
| Liu, R | 1 |
| Chang, S | 1 |
| Li, X | 3 |
| Weng, X | 1 |
| Lian, G | 1 |
| Zhang, Y | 2 |
| Sun, L | 1 |
| Pang, Y | 1 |
| Jiang, C | 1 |
| Ren, W | 1 |
| Wang, Z | 3 |
| Wu, Z | 1 |
| Ren, Q | 1 |
| Yu, A | 1 |
| Ruan, Y | 1 |
| Wang, K | 1 |
| Zhao, J | 2 |
| Zhang, W | 2 |
| Zhu, M | 1 |
| Xu, M | 1 |
| Shi, H | 1 |
| Zhang, M | 1 |
| Shi, J | 1 |
| Hayashi-Hori, M | 1 |
| Aoki, H | 1 |
| Matsukuma, M | 1 |
| Majima, R | 1 |
| Hashimoto, Y | 1 |
| Ito, S | 1 |
| Hirakata, S | 1 |
| Nishida, N | 1 |
| Furusho, A | 1 |
| Ohno-Urabe, S | 1 |
| Fukumoto, Y | 1 |
| Li, G | 1 |
| Huang, S | 1 |
| Qiao, B | 1 |
| Li, Y | 3 |
| Du, J | 3 |
| Li, P | 3 |
| Piao, J | 1 |
| Park, JS | 1 |
| Hwang, DY | 1 |
| Hong, HS | 1 |
| Son, Y | 1 |
| Guo, LL | 1 |
| Wu, MT | 1 |
| Zhang, LW | 1 |
| Chu, YX | 1 |
| Tian, P | 1 |
| Jing, ZP | 4 |
| Li, JS | 2 |
| Sun, YD | 1 |
| Yeung, KK | 1 |
| Kondo, M | 1 |
| Izawa-Ishizawa, Y | 1 |
| Goda, M | 1 |
| Hosooka, M | 1 |
| Kagimoto, Y | 1 |
| Saito, N | 1 |
| Matsuoka, R | 1 |
| Zamami, Y | 1 |
| Chuma, M | 1 |
| Yagi, K | 1 |
| Takechi, K | 1 |
| Tsuneyama, K | 1 |
| Ishizawa, K | 1 |
| Qi, X | 1 |
| Wang, F | 1 |
| Chun, C | 1 |
| Saldarriaga, L | 1 |
| Jiang, Z | 2 |
| Pruitt, EY | 1 |
| Arnaoutakis, GJ | 1 |
| Upchurch, GR | 1 |
| Lv, X | 1 |
| Hu, Y | 1 |
| Chen, X | 2 |
| Chen, L | 1 |
| Lin, Y | 1 |
| Hou, Y | 1 |
| Qiu, T | 1 |
| Yang, Y | 1 |
| Li, Q | 1 |
| Chen, SW | 1 |
| Chou, SH | 1 |
| Tung, YC | 1 |
| Hsiao, FC | 1 |
| Ho, CT | 1 |
| Chan, YH | 1 |
| Wu, VC | 1 |
| Chou, AH | 1 |
| Hsu, ME | 1 |
| Lin, PJ | 1 |
| Kao, WWY | 1 |
| Chu, PH | 1 |
| Zheng, X | 1 |
| Xu, K | 1 |
| Qi, F | 1 |
| Yu, B | 2 |
| Jia, L | 2 |
| Xu, FJ | 1 |
| Han, L | 1 |
| Dai, L | 1 |
| Zhao, YF | 1 |
| Li, HY | 2 |
| Liu, O | 1 |
| Lan, F | 1 |
| Jiang, WJ | 1 |
| Zhang, HJ | 1 |
| Chen, B | 1 |
| Liu, L | 1 |
| Sun, J | 1 |
| You, B | 1 |
| Liu, Y | 1 |
| Zhao, G | 2 |
| He, L | 1 |
| Yu, C | 2 |
| Zhao, T | 1 |
| Cao, F | 1 |
| Zheng, J | 2 |
| Ma, B | 1 |
| Sun, W | 1 |
| Guo, J | 1 |
| Tu, Y | 1 |
| Pan, L | 1 |
| Zhang, Z | 1 |
| Jiang, Y | 1 |
| Zhou, Z | 1 |
| Chen, S | 1 |
| Zhou, W | 1 |
| Bai, H | 1 |
| Zhang, H | 1 |
| Ben, J | 1 |
| Zhu, X | 1 |
| Anzai, A | 1 |
| Shimoda, M | 1 |
| Endo, J | 1 |
| Kohno, T | 1 |
| Katsumata, Y | 1 |
| Matsuhashi, T | 1 |
| Yamamoto, T | 1 |
| Ito, K | 1 |
| Yan, X | 1 |
| Shirakawa, K | 1 |
| Shimizu-Hirota, R | 1 |
| Yamada, Y | 1 |
| Ueha, S | 1 |
| Shinmura, K | 1 |
| Okada, Y | 1 |
| Fukuda, K | 1 |
| Sano, M | 1 |
| Wang, Y | 1 |
| Zhao, ZM | 1 |
| Zhang, GX | 1 |
| Yang, F | 1 |
| Yan, Y | 1 |
| Liu, SX | 1 |
| Li, SH | 1 |
| Wang, GK | 1 |
| Xu, ZY | 1 |
| Kanematsu, Y | 1 |
| Kanematsu, M | 1 |
| Kurihara, C | 1 |
| Tsou, TL | 1 |
| Nuki, Y | 1 |
| Liang, EI | 1 |
| Makino, H | 1 |
| Hashimoto, T | 1 |
| Pei, YF | 1 |
| Liao, MF | 1 |
| Lu, QS | 2 |
| Zhuang, YF | 1 |
| Zhang, SM | 1 |
| Lu, H | 1 |
| Lin, C | 1 |
| Bao, JM | 1 |
| Nagashima, H | 1 |
| Uto, K | 1 |
| Sakomura, Y | 1 |
| Aoka, Y | 1 |
| Sakuta, A | 1 |
| Aomi, S | 1 |
| Hagiwara, N | 1 |
| Kawana, M | 1 |
| Kasanuki, H | 1 |
| WAIBEL, PE | 2 |
| LOVELADY, HG | 1 |
| LIENER, IE | 1 |
| BALL, RA | 1 |
| SAUTTER, JH | 1 |
| POMEROY, BS | 1 |
| Nakashima, Y | 1 |
| Sueishi, K | 1 |
| Hosoda, Y | 1 |
| Suzuki, M | 1 |
| O'Neal, RM | 1 |
44 other studies available for aminopropionitrile and Aortic Dissection
| Article | Year |
|---|---|
Pan-HDAC (Histone Deacetylase) Inhibitors Increase Susceptibility of Thoracic Aortic Aneurysm and Dissection in Mice.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cefixime | 2021 |
Methamphetamine induces thoracic aortic aneurysm/dissection through C/EBPβ.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; CCAAT-Enhancer-Binding Pr | 2022 |
ALDH
Topics: Aldehyde Dehydrogenase, Mitochondrial; Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aorti | 2022 |
Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease Models, Animal; Elastin; Hum | 2022 |
11S Proteasome Activator REGγ Promotes Aortic Dissection by Inhibiting RBM3 (RNA Binding Motif Protein 3) Pathway.
Topics: Aminopropionitrile; Animals; Aortic Dissection; Mice; Proteasome Endopeptidase Complex; RNA-Binding | 2023 |
Smooth Muscle Cell Relaxation Worsens Aortic Dilatation and Clinical Presentation in a BAPN/Angiotensin II-Induced Aortic Dissection Model in Rats.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Dilatation; Disease Models, Animal; | 2022 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Targeting endothelial tight junctions to predict and protect thoracic aortic aneurysm and dissection.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Mice; Signal Transduction | 2023 |
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice.
Topics: Aminopropionitrile; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; C | 2023 |
Low Zinc Alleviates the Progression of Thoracic Aortic Dissection by Inhibiting Inflammation.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease | 2023 |
Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice.
Topics: Allopurinol; Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Mode | 2023 |
Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Dissection, Thoracic Aort | 2023 |
Gut Microbiota-Derived Tryptophan Metabolite Indole-3-aldehyde Ameliorates Aortic Dissection.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Models, Animal; G | 2023 |
Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway
Topics: Acriflavine; ADAM17 Protein; Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease | 2019 |
IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Dissection; Apoptosis; Case-Control Studi | 2020 |
Resveratrol Attenuates Aortic Dissection by Increasing Endothelial Barrier Function Through the SIRT1 Pathway.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm; Aortic Dissection; Ce | 2020 |
Therapeutic Effect of Rapamycin on Aortic Dissection in Mice.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Cell Cycle Checkpoints; Cell Line; D | 2020 |
Effects of Extracellular Matrix Softening on Vascular Smooth Muscle Cell Dysfunction.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cell Ded | 2020 |
Substance P blocks β-aminopropionitrile-induced aortic injury through modulation of M2 monocyte-skewed monocytopoiesis.
Topics: Aminopropionitrile; Animals; Aortic Dissection; Humans; Mice; Mice, Inbred C57BL; Monocytes; Rats; R | 2021 |
Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model.
Topics: Aminopropionitrile; Animals; Antibodies; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2020 |
Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; At | 2020 |
A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs).
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Disease Mode | 2020 |
Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Diss | 2021 |
Dexamethasone reduces the formation of thoracic aortic aneurysm and dissection in a murine model.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Dexamethasone; Macrophage | 2021 |
Expression and role of lumican in acute aortic dissection: A human and mouse study.
Topics: Acute Disease; Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Dissection; Aortic Rupture | 2021 |
Bilateral superior cervical ganglionectomy attenuates the progression of β-aminopropionitrile-induced aortic dissection in rats.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Dissection; Arterial Pressure; Disease Models, Animal; Di | 2018 |
Identification of type IV collagen exposure as a molecular imaging target for early detection of thoracic aortic dissection.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Dissection; Cell Line; Collagen Type IV; Early Diagnosis; | 2018 |
CD40L promotes development of acute aortic dissection via induction of inflammation and impairment of endothelial cell function.
Topics: Aminopropionitrile; Animals; Aortic Dissection; Blood Platelets; Case-Control Studies; CD40 Ligand; | 2018 |
Interleukin-3 stimulates matrix metalloproteinase 12 production from macrophages promoting thoracic aortic aneurysm/dissection.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cells, C | 2018 |
Postnatal deficiency of ADAMTS1 ameliorates thoracic aortic aneurysm and dissection in mice.
Topics: ADAMTS1 Protein; Aminopropionitrile; Animals; Aorta; Aortic Aneurysm, Thoracic; Aortic Dissection; D | 2018 |
Rapamycin prevents thoracic aortic aneurysm and dissection in mice.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aortic Aneurysm, Thoracic; A | 2019 |
Involvement of B cells in the pathophysiology of β-aminopropionitrile-induced thoracic aortic dissection in mice.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Dissection; B-Lymphocytes; Male; Mice; Mice, In | 2019 |
Scavenger receptor A1 attenuates aortic dissection via promoting efferocytosis in macrophages.
Topics: Aminopropionitrile; Animals; Aortic Dissection; Apoptosis; Enzyme Inhibitors; Gene Expression Regula | 2019 |
Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic R | 2013 |
Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.
Topics: Acute Disease; Adventitia; Aged; Aminopropionitrile; Angiotensin II; Animals; Antibodies, Monoclonal | 2015 |
Dynamic autophagic activity affected the development of thoracic aortic dissection by regulating functional properties of smooth muscle cells.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Dissection; Apoptosis; Autophag | 2016 |
Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.
Topics: Aminopropionitrile; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, A | 2010 |
Dramatic decrease of aortic longitudinal elastic strength in a rat model of aortic dissection.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic R | 2012 |
[Biomechanical properties study of aorta in β-aminopropionitrile-induced rat model].
Topics: Aminopropionitrile; Animals; Aorta; Aortic Dissection; Biomechanical Phenomena; Disease Models, Anim | 2012 |
An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats.
Topics: Aminopropionitrile; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anim | 2002 |
INFLUENCE OF BETA-AMINOPROPIONITRILE ON DISSECTING ANEURYSM AND ON PLASMA AMINO ACIDS IN THE TURKEY.
Topics: Alanine; Amino Acids; Aminopropionitrile; Ammonia; Aneurysm; Animals; Aortic Dissection; Arginine; A | 1964 |
NATURAL AND EXPERIMENTAL DISSECTING ANEURYSMS IN TURKEYS.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm; Aortic Dissection; Aortic Rupture; Bone and Bones; Car | 1965 |
Alteration of elastic architecture in the lathyritic rat aorta implies the pathogenesis of aortic dissecting aneurysm.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Body Weight; | 1992 |
Angiolathyrism. III. Vasa vasorum in experimental dissecting aortic aneurysm.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm; Aortic Dissection; Histocytochemistry; Lathyrism; Male | 1968 |