aminopropionitrile has been researched along with Aortic Aneurysm, Thoracic in 27 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
Aortic Aneurysm, Thoracic: An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Given the controversy regarding the appropriate dose of β-aminopropionitrile for induction of aortic dissection models in rats, the purpose of this study was to explore the most suitable concentration of β-aminopropionitrile to establish a high-incidence and low-mortality aortic dissection model." | 8.02 | Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats. ( Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X, 2021) |
| "This study compared three β-aminopropionitrile (BAPN) treatment rats to find the optimal BAPN model for thoracic aortic dissection and aneurysm in one study." | 7.79 | Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage. ( Jing, ZP; Li, HY; Li, JS; Wang, L; Zhang, L, 2013) |
| "This study uncovered an important and previously unrecognized role of hyperuricemia in mediating the pathogenesis of TAAD, and uric acid-lowering drug may represent a promising therapeutic approach for TAAD." | 4.31 | Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice. ( Cai, Z; Dai, R; Fu, Y; Gong, Z; Kong, W; Li, W; Li, Z; Luo, C; Shen, Y; Wang, J; Wu, H; Yang, L; Yu, F; Zhang, T; Zhang, X; Zhao, H; Zhao, Y; Zhu, J, 2023) |
| "Given the controversy regarding the appropriate dose of β-aminopropionitrile for induction of aortic dissection models in rats, the purpose of this study was to explore the most suitable concentration of β-aminopropionitrile to establish a high-incidence and low-mortality aortic dissection model." | 4.02 | Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats. ( Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X, 2021) |
| "This study compared three β-aminopropionitrile (BAPN) treatment rats to find the optimal BAPN model for thoracic aortic dissection and aneurysm in one study." | 3.79 | Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage. ( Jing, ZP; Li, HY; Li, JS; Wang, L; Zhang, L, 2013) |
| "β-aminopropionitrile monofumarate was administrated in mice to induce TAD." | 1.91 | Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice. ( Chen, D; Chen, Q; Cutillas, PR; Li, D; Liu, C; Luo, J; Niu, K; Pearce, SWA; Shao, Y; Wu, Q; Xiao, Q; Yang, M; Yang, Z; Zhang, C; Zhang, L; Zhao, L; Zhou, X, 2023) |
| "Combination of METH and BAPN caused thoracic aortic aneurysm/dissection in 60% of rats." | 1.72 | Methamphetamine induces thoracic aortic aneurysm/dissection through C/EBPβ. ( Cai, DP; Chen, SY; Guo, D; Luo, BY; Tian, Q; Wang, HJ; Xie, WB; Xu, ZZ; Yang, Q; Zhou, J; Zhou, RM, 2022) |
| "The incidence and mortality of aortic dissection (AD) are increasing." | 1.72 | ALDH ( Cui, Y; Liu, Z; Luo, C; Wang, S; Zhou, B, 2022) |
| "Thoracic aortic dissection (TAD) is associated with matrix changes, biochemical changes, and inflammatory markers like interleukin-1 beta (IL-1β)." | 1.56 | Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model. ( Chu, YX; Guo, LL; Jing, ZP; Li, JS; Sun, YD; Tian, P; Wu, MT; Yeung, KK; Zhang, L; Zhang, LW, 2020) |
| "Azelnidipine treatment reduced the pathologic findings normally associated with aneurysm formation within the aortic wall." | 1.39 | Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects. ( Hirata, Y; Kitagawa, T; Kurobe, H; Matsuoka, Y; Maxfield, MW; Sata, M; Sugasawa, N, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (40.74) | 24.3611 |
| 2020's | 16 (59.26) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, S | 1 |
| Liu, Z | 3 |
| Xie, N | 2 |
| Huang, C | 1 |
| Li, Z | 5 |
| Yu, F | 3 |
| Fu, Y | 6 |
| Cui, Q | 1 |
| Kong, W | 6 |
| Luo, BY | 1 |
| Zhou, J | 1 |
| Guo, D | 1 |
| Yang, Q | 1 |
| Tian, Q | 1 |
| Cai, DP | 1 |
| Zhou, RM | 1 |
| Xu, ZZ | 1 |
| Wang, HJ | 1 |
| Chen, SY | 1 |
| Xie, WB | 1 |
| Sawada, H | 2 |
| Ohno-Urabe, S | 2 |
| Ye, D | 1 |
| Franklin, MK | 2 |
| Moorleghen, JJ | 1 |
| Howatt, DA | 1 |
| Mullick, AE | 1 |
| Daugherty, A | 2 |
| Lu, HS | 2 |
| Luo, C | 3 |
| Zhou, B | 2 |
| Cui, Y | 1 |
| Wang, S | 2 |
| Yang, YY | 2 |
| Jiao, XL | 2 |
| Yu, HH | 2 |
| Li, LY | 2 |
| Li, J | 2 |
| Zhang, XP | 2 |
| Qin, YW | 3 |
| Yang, X | 1 |
| Xu, C | 1 |
| Yao, F | 1 |
| Ding, Q | 1 |
| Liu, H | 2 |
| Wang, D | 2 |
| Huang, J | 2 |
| Shen, Y | 2 |
| Yang, W | 1 |
| Wang, L | 3 |
| Ma, Q | 2 |
| Zhu, J | 2 |
| Xu, F | 1 |
| Cong, X | 1 |
| Gong, Z | 3 |
| Yang, S | 1 |
| Ma, Z | 1 |
| Zhu, L | 1 |
| An, P | 1 |
| Zhao, W | 1 |
| Xia, Y | 1 |
| Qi, J | 1 |
| Luo, J | 2 |
| Luo, Y | 1 |
| Yang, L | 1 |
| Wu, H | 1 |
| Zhao, Y | 1 |
| Dai, R | 2 |
| Zhang, X | 4 |
| Cai, Z | 1 |
| Li, W | 2 |
| Zhao, H | 1 |
| Zhang, T | 1 |
| Wang, J | 1 |
| Yang, M | 1 |
| Zhou, X | 1 |
| Pearce, SWA | 1 |
| Yang, Z | 1 |
| Chen, Q | 1 |
| Niu, K | 1 |
| Liu, C | 2 |
| Li, D | 1 |
| Shao, Y | 2 |
| Zhang, C | 2 |
| Chen, D | 2 |
| Wu, Q | 1 |
| Cutillas, PR | 1 |
| Zhao, L | 1 |
| Xiao, Q | 1 |
| Zhang, L | 4 |
| Huang, SS | 1 |
| Liu, R | 1 |
| Chang, S | 1 |
| Li, X | 1 |
| Weng, X | 1 |
| Ge, J | 1 |
| Li, G | 1 |
| Huang, S | 1 |
| Qiao, B | 1 |
| Li, Y | 2 |
| Du, J | 4 |
| Li, P | 2 |
| Guo, LL | 1 |
| Wu, MT | 1 |
| Zhang, LW | 1 |
| Chu, YX | 1 |
| Tian, P | 1 |
| Jing, ZP | 3 |
| Li, JS | 2 |
| Sun, YD | 1 |
| Yeung, KK | 1 |
| Lv, X | 1 |
| Hu, Y | 1 |
| Chen, X | 2 |
| Chen, L | 1 |
| Lin, Y | 1 |
| Hou, Y | 1 |
| Kukida, M | 1 |
| Katsumata, Y | 2 |
| Su, W | 1 |
| Gong, MC | 1 |
| Wang, X | 2 |
| Qiu, T | 1 |
| Yang, Y | 1 |
| Li, Q | 1 |
| Jia, L | 2 |
| Chen, B | 1 |
| Liu, L | 1 |
| Sun, J | 1 |
| Zhang, W | 1 |
| You, B | 1 |
| Liu, Y | 2 |
| Zhao, G | 2 |
| He, L | 1 |
| Yu, C | 1 |
| Wang, Z | 1 |
| Zhao, T | 1 |
| Cao, F | 1 |
| Gao, Y | 1 |
| Zheng, J | 1 |
| Yu, B | 1 |
| Ma, B | 1 |
| Li, HY | 1 |
| Kurobe, H | 1 |
| Matsuoka, Y | 1 |
| Hirata, Y | 1 |
| Sugasawa, N | 1 |
| Maxfield, MW | 1 |
| Sata, M | 1 |
| Kitagawa, T | 1 |
| Anzai, A | 1 |
| Shimoda, M | 1 |
| Endo, J | 1 |
| Kohno, T | 1 |
| Matsuhashi, T | 1 |
| Yamamoto, T | 1 |
| Ito, K | 1 |
| Yan, X | 1 |
| Shirakawa, K | 1 |
| Shimizu-Hirota, R | 1 |
| Yamada, Y | 1 |
| Ueha, S | 1 |
| Shinmura, K | 1 |
| Okada, Y | 1 |
| Fukuda, K | 1 |
| Sano, M | 1 |
| Jia, LX | 1 |
| Zhang, WM | 1 |
| Zhang, HJ | 1 |
| Li, TT | 1 |
| Wang, YL | 1 |
| Gu, H | 1 |
| Ren, W | 1 |
| Piao, C | 1 |
| Lan, F | 1 |
| Imanishi, M | 1 |
| Chiba, Y | 1 |
| Tomita, N | 1 |
| Matsunaga, S | 1 |
| Nakagawa, T | 1 |
| Ueno, M | 1 |
| Yamamoto, K | 1 |
| Tamaki, T | 1 |
| Tomita, S | 1 |
| Kanematsu, Y | 1 |
| Kanematsu, M | 1 |
| Kurihara, C | 1 |
| Tsou, TL | 1 |
| Nuki, Y | 1 |
| Liang, EI | 1 |
| Makino, H | 1 |
| Hashimoto, T | 1 |
| Pei, YF | 1 |
| Liao, MF | 1 |
| Lu, QS | 1 |
| Zhuang, YF | 1 |
| Zhang, SM | 1 |
27 other studies available for aminopropionitrile and Aortic Aneurysm, Thoracic
| Article | Year |
|---|---|
Pan-HDAC (Histone Deacetylase) Inhibitors Increase Susceptibility of Thoracic Aortic Aneurysm and Dissection in Mice.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cefixime | 2021 |
Methamphetamine induces thoracic aortic aneurysm/dissection through C/EBPβ.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; CCAAT-Enhancer-Binding Pr | 2022 |
Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile-Induced Thoracic Aortopathy in Mice-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Angiotensinogen; Animals; Aortic Aneurysm, Thoracic; Aortic Rupt | 2022 |
ALDH
Topics: Aldehyde Dehydrogenase, Mitochondrial; Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aorti | 2022 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Targeting endothelial tight junctions to predict and protect thoracic aortic aneurysm and dissection.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Mice; Signal Transduction | 2023 |
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice.
Topics: Aminopropionitrile; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; C | 2023 |
Low Zinc Alleviates the Progression of Thoracic Aortic Dissection by Inhibiting Inflammation.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease | 2023 |
Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice.
Topics: Allopurinol; Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Mode | 2023 |
Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Dissection, Thoracic Aort | 2023 |
Gut Microbiota-Derived Tryptophan Metabolite Indole-3-aldehyde Ameliorates Aortic Dissection.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Models, Animal; G | 2023 |
Effects of Extracellular Matrix Softening on Vascular Smooth Muscle Cell Dysfunction.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cell Ded | 2020 |
Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model.
Topics: Aminopropionitrile; Animals; Antibodies; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2020 |
Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Diss | 2021 |
Authentication of In Situ Measurements for Thoracic Aortic Aneurysms in Mice.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Dilatation, Pathologic; Dis | 2021 |
Dexamethasone reduces the formation of thoracic aortic aneurysm and dissection in a murine model.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Dexamethasone; Macrophage | 2021 |
Interleukin-3 stimulates matrix metalloproteinase 12 production from macrophages promoting thoracic aortic aneurysm/dissection.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cells, C | 2018 |
Postnatal deficiency of ADAMTS1 ameliorates thoracic aortic aneurysm and dissection in mice.
Topics: ADAMTS1 Protein; Aminopropionitrile; Animals; Aorta; Aortic Aneurysm, Thoracic; Aortic Dissection; D | 2018 |
Rapamycin prevents thoracic aortic aneurysm and dissection in mice.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aortic Aneurysm, Thoracic; A | 2019 |
Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic R | 2013 |
Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects.
Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aorta, Thor | 2013 |
Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.
Topics: Acute Disease; Adventitia; Aged; Aminopropionitrile; Angiotensin II; Animals; Antibodies, Monoclonal | 2015 |
Mechanical stretch-induced endoplasmic reticulum stress, apoptosis and inflammation contribute to thoracic aortic aneurysm and dissection.
Topics: Activating Transcription Factor 4; Aminopropionitrile; Animals; Aorta; Aortic Aneurysm, Thoracic; Ap | 2015 |
β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice.
Topics: Actins; Aminopropionitrile; Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Blood Pressure; Body | 2016 |
Hypoxia-Inducible Factor-1α in Smooth Muscle Cells Protects Against Aortic Aneurysms-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abd | 2016 |
Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.
Topics: Aminopropionitrile; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, A | 2010 |
Dramatic decrease of aortic longitudinal elastic strength in a rat model of aortic dissection.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic R | 2012 |