aminopropionitrile has been researched along with Aneurysm, Thoracic Aortic in 27 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Given the controversy regarding the appropriate dose of β-aminopropionitrile for induction of aortic dissection models in rats, the purpose of this study was to explore the most suitable concentration of β-aminopropionitrile to establish a high-incidence and low-mortality aortic dissection model." | 8.02 | Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats. ( Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X, 2021) |
| "This study compared three β-aminopropionitrile (BAPN) treatment rats to find the optimal BAPN model for thoracic aortic dissection and aneurysm in one study." | 7.79 | Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage. ( Jing, ZP; Li, HY; Li, JS; Wang, L; Zhang, L, 2013) |
| "This study uncovered an important and previously unrecognized role of hyperuricemia in mediating the pathogenesis of TAAD, and uric acid-lowering drug may represent a promising therapeutic approach for TAAD." | 4.31 | Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice. ( Cai, Z; Dai, R; Fu, Y; Gong, Z; Kong, W; Li, W; Li, Z; Luo, C; Shen, Y; Wang, J; Wu, H; Yang, L; Yu, F; Zhang, T; Zhang, X; Zhao, H; Zhao, Y; Zhu, J, 2023) |
| "Given the controversy regarding the appropriate dose of β-aminopropionitrile for induction of aortic dissection models in rats, the purpose of this study was to explore the most suitable concentration of β-aminopropionitrile to establish a high-incidence and low-mortality aortic dissection model." | 4.02 | Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats. ( Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X, 2021) |
| "This study compared three β-aminopropionitrile (BAPN) treatment rats to find the optimal BAPN model for thoracic aortic dissection and aneurysm in one study." | 3.79 | Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage. ( Jing, ZP; Li, HY; Li, JS; Wang, L; Zhang, L, 2013) |
| "β-aminopropionitrile monofumarate was administrated in mice to induce TAD." | 1.91 | Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice. ( Chen, D; Chen, Q; Cutillas, PR; Li, D; Liu, C; Luo, J; Niu, K; Pearce, SWA; Shao, Y; Wu, Q; Xiao, Q; Yang, M; Yang, Z; Zhang, C; Zhang, L; Zhao, L; Zhou, X, 2023) |
| "Combination of METH and BAPN caused thoracic aortic aneurysm/dissection in 60% of rats." | 1.72 | Methamphetamine induces thoracic aortic aneurysm/dissection through C/EBPβ. ( Cai, DP; Chen, SY; Guo, D; Luo, BY; Tian, Q; Wang, HJ; Xie, WB; Xu, ZZ; Yang, Q; Zhou, J; Zhou, RM, 2022) |
| "The incidence and mortality of aortic dissection (AD) are increasing." | 1.72 | ALDH ( Cui, Y; Liu, Z; Luo, C; Wang, S; Zhou, B, 2022) |
| "Thoracic aortic dissection (TAD) is associated with matrix changes, biochemical changes, and inflammatory markers like interleukin-1 beta (IL-1β)." | 1.56 | Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model. ( Chu, YX; Guo, LL; Jing, ZP; Li, JS; Sun, YD; Tian, P; Wu, MT; Yeung, KK; Zhang, L; Zhang, LW, 2020) |
| "Azelnidipine treatment reduced the pathologic findings normally associated with aneurysm formation within the aortic wall." | 1.39 | Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects. ( Hirata, Y; Kitagawa, T; Kurobe, H; Matsuoka, Y; Maxfield, MW; Sata, M; Sugasawa, N, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (40.74) | 24.3611 |
| 2020's | 16 (59.26) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, S | 1 |
| Liu, Z | 3 |
| Xie, N | 2 |
| Huang, C | 1 |
| Li, Z | 5 |
| Yu, F | 3 |
| Fu, Y | 6 |
| Cui, Q | 1 |
| Kong, W | 6 |
| Luo, BY | 1 |
| Zhou, J | 1 |
| Guo, D | 1 |
| Yang, Q | 1 |
| Tian, Q | 1 |
| Cai, DP | 1 |
| Zhou, RM | 1 |
| Xu, ZZ | 1 |
| Wang, HJ | 1 |
| Chen, SY | 1 |
| Xie, WB | 1 |
| Sawada, H | 2 |
| Ohno-Urabe, S | 2 |
| Ye, D | 1 |
| Franklin, MK | 2 |
| Moorleghen, JJ | 1 |
| Howatt, DA | 1 |
| Mullick, AE | 1 |
| Daugherty, A | 2 |
| Lu, HS | 2 |
| Luo, C | 3 |
| Zhou, B | 2 |
| Cui, Y | 1 |
| Wang, S | 2 |
| Yang, YY | 2 |
| Jiao, XL | 2 |
| Yu, HH | 2 |
| Li, LY | 2 |
| Li, J | 2 |
| Zhang, XP | 2 |
| Qin, YW | 3 |
| Yang, X | 1 |
| Xu, C | 1 |
| Yao, F | 1 |
| Ding, Q | 1 |
| Liu, H | 2 |
| Wang, D | 2 |
| Huang, J | 2 |
| Shen, Y | 2 |
| Yang, W | 1 |
| Wang, L | 3 |
| Ma, Q | 2 |
| Zhu, J | 2 |
| Xu, F | 1 |
| Cong, X | 1 |
| Gong, Z | 3 |
| Yang, S | 1 |
| Ma, Z | 1 |
| Zhu, L | 1 |
| An, P | 1 |
| Zhao, W | 1 |
| Xia, Y | 1 |
| Qi, J | 1 |
| Luo, J | 2 |
| Luo, Y | 1 |
| Yang, L | 1 |
| Wu, H | 1 |
| Zhao, Y | 1 |
| Dai, R | 2 |
| Zhang, X | 4 |
| Cai, Z | 1 |
| Li, W | 2 |
| Zhao, H | 1 |
| Zhang, T | 1 |
| Wang, J | 1 |
| Yang, M | 1 |
| Zhou, X | 1 |
| Pearce, SWA | 1 |
| Yang, Z | 1 |
| Chen, Q | 1 |
| Niu, K | 1 |
| Liu, C | 2 |
| Li, D | 1 |
| Shao, Y | 2 |
| Zhang, C | 2 |
| Chen, D | 2 |
| Wu, Q | 1 |
| Cutillas, PR | 1 |
| Zhao, L | 1 |
| Xiao, Q | 1 |
| Zhang, L | 4 |
| Huang, SS | 1 |
| Liu, R | 1 |
| Chang, S | 1 |
| Li, X | 1 |
| Weng, X | 1 |
| Ge, J | 1 |
| Li, G | 1 |
| Huang, S | 1 |
| Qiao, B | 1 |
| Li, Y | 2 |
| Du, J | 4 |
| Li, P | 2 |
| Guo, LL | 1 |
| Wu, MT | 1 |
| Zhang, LW | 1 |
| Chu, YX | 1 |
| Tian, P | 1 |
| Jing, ZP | 3 |
| Li, JS | 2 |
| Sun, YD | 1 |
| Yeung, KK | 1 |
| Lv, X | 1 |
| Hu, Y | 1 |
| Chen, X | 2 |
| Chen, L | 1 |
| Lin, Y | 1 |
| Hou, Y | 1 |
| Kukida, M | 1 |
| Katsumata, Y | 2 |
| Su, W | 1 |
| Gong, MC | 1 |
| Wang, X | 2 |
| Qiu, T | 1 |
| Yang, Y | 1 |
| Li, Q | 1 |
| Jia, L | 2 |
| Chen, B | 1 |
| Liu, L | 1 |
| Sun, J | 1 |
| Zhang, W | 1 |
| You, B | 1 |
| Liu, Y | 2 |
| Zhao, G | 2 |
| He, L | 1 |
| Yu, C | 1 |
| Wang, Z | 1 |
| Zhao, T | 1 |
| Cao, F | 1 |
| Gao, Y | 1 |
| Zheng, J | 1 |
| Yu, B | 1 |
| Ma, B | 1 |
| Li, HY | 1 |
| Kurobe, H | 1 |
| Matsuoka, Y | 1 |
| Hirata, Y | 1 |
| Sugasawa, N | 1 |
| Maxfield, MW | 1 |
| Sata, M | 1 |
| Kitagawa, T | 1 |
| Anzai, A | 1 |
| Shimoda, M | 1 |
| Endo, J | 1 |
| Kohno, T | 1 |
| Matsuhashi, T | 1 |
| Yamamoto, T | 1 |
| Ito, K | 1 |
| Yan, X | 1 |
| Shirakawa, K | 1 |
| Shimizu-Hirota, R | 1 |
| Yamada, Y | 1 |
| Ueha, S | 1 |
| Shinmura, K | 1 |
| Okada, Y | 1 |
| Fukuda, K | 1 |
| Sano, M | 1 |
| Jia, LX | 1 |
| Zhang, WM | 1 |
| Zhang, HJ | 1 |
| Li, TT | 1 |
| Wang, YL | 1 |
| Gu, H | 1 |
| Ren, W | 1 |
| Piao, C | 1 |
| Lan, F | 1 |
| Imanishi, M | 1 |
| Chiba, Y | 1 |
| Tomita, N | 1 |
| Matsunaga, S | 1 |
| Nakagawa, T | 1 |
| Ueno, M | 1 |
| Yamamoto, K | 1 |
| Tamaki, T | 1 |
| Tomita, S | 1 |
| Kanematsu, Y | 1 |
| Kanematsu, M | 1 |
| Kurihara, C | 1 |
| Tsou, TL | 1 |
| Nuki, Y | 1 |
| Liang, EI | 1 |
| Makino, H | 1 |
| Hashimoto, T | 1 |
| Pei, YF | 1 |
| Liao, MF | 1 |
| Lu, QS | 1 |
| Zhuang, YF | 1 |
| Zhang, SM | 1 |
27 other studies available for aminopropionitrile and Aneurysm, Thoracic Aortic
| Article | Year |
|---|---|
Pan-HDAC (Histone Deacetylase) Inhibitors Increase Susceptibility of Thoracic Aortic Aneurysm and Dissection in Mice.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cefixime | 2021 |
Methamphetamine induces thoracic aortic aneurysm/dissection through C/EBPβ.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; CCAAT-Enhancer-Binding Pr | 2022 |
Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile-Induced Thoracic Aortopathy in Mice-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Angiotensinogen; Animals; Aortic Aneurysm, Thoracic; Aortic Rupt | 2022 |
ALDH
Topics: Aldehyde Dehydrogenase, Mitochondrial; Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aorti | 2022 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Topics: Aminopropionitrile; Angiopoietin-Like Protein 8; Animals; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2023 |
Targeting endothelial tight junctions to predict and protect thoracic aortic aneurysm and dissection.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Mice; Signal Transduction | 2023 |
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice.
Topics: Aminopropionitrile; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; C | 2023 |
Low Zinc Alleviates the Progression of Thoracic Aortic Dissection by Inhibiting Inflammation.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease | 2023 |
Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice.
Topics: Allopurinol; Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Mode | 2023 |
Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Dissection, Thoracic Aort | 2023 |
Gut Microbiota-Derived Tryptophan Metabolite Indole-3-aldehyde Ameliorates Aortic Dissection.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Models, Animal; G | 2023 |
Effects of Extracellular Matrix Softening on Vascular Smooth Muscle Cell Dysfunction.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cell Ded | 2020 |
Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model.
Topics: Aminopropionitrile; Animals; Antibodies; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissecti | 2020 |
Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Diss | 2021 |
Authentication of In Situ Measurements for Thoracic Aortic Aneurysms in Mice.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Dilatation, Pathologic; Dis | 2021 |
Dexamethasone reduces the formation of thoracic aortic aneurysm and dissection in a murine model.
Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Dexamethasone; Macrophage | 2021 |
Interleukin-3 stimulates matrix metalloproteinase 12 production from macrophages promoting thoracic aortic aneurysm/dissection.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cells, C | 2018 |
Postnatal deficiency of ADAMTS1 ameliorates thoracic aortic aneurysm and dissection in mice.
Topics: ADAMTS1 Protein; Aminopropionitrile; Animals; Aorta; Aortic Aneurysm, Thoracic; Aortic Dissection; D | 2018 |
Rapamycin prevents thoracic aortic aneurysm and dissection in mice.
Topics: Aminopropionitrile; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aortic Aneurysm, Thoracic; A | 2019 |
Comparison of β-aminopropionitrile-induced aortic dissection model in rats by different administration and dosage.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic R | 2013 |
Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects.
Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aorta, Thor | 2013 |
Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.
Topics: Acute Disease; Adventitia; Aged; Aminopropionitrile; Angiotensin II; Animals; Antibodies, Monoclonal | 2015 |
Mechanical stretch-induced endoplasmic reticulum stress, apoptosis and inflammation contribute to thoracic aortic aneurysm and dissection.
Topics: Activating Transcription Factor 4; Aminopropionitrile; Animals; Aorta; Aortic Aneurysm, Thoracic; Ap | 2015 |
β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice.
Topics: Actins; Aminopropionitrile; Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Blood Pressure; Body | 2016 |
Hypoxia-Inducible Factor-1α in Smooth Muscle Cells Protects Against Aortic Aneurysms-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abd | 2016 |
Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.
Topics: Aminopropionitrile; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, A | 2010 |
Dramatic decrease of aortic longitudinal elastic strength in a rat model of aortic dissection.
Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic R | 2012 |