Page last updated: 2024-10-21

aminopropionitrile and Abdominal Aortic Aneurysm

aminopropionitrile has been researched along with Abdominal Aortic Aneurysm in 19 studies

Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.

Research Excerpts

ExcerptRelevanceReference
"Angiotensin II (AngII)-activated epidermal growth factor receptor has been implicated in abdominal aortic aneurysm (AAA) development."7.85Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm. ( Boyer, MJ; Cooper, HA; Eguchi, S; Forrester, SJ; Hashimoto, T; Kawai, T; Kobayashi, T; Kwok, HF; Obama, T; Preston, KJ; Rizzo, V; Scalia, R; Takayanagi, T; Tsuji, T, 2017)
"Angiotensin II (AngII) is a potential contributor to the development of abdominal aortic aneurysm (AAA)."4.02Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm. ( Choi, ET; Cicalese, S; Cooper, HA; Eguchi, S; Kasahara, S; Kawai, T; Okuno, K; Otaka, N; Preston, KJ; Rizzo, V; Scalia, R; Uchida, HA, 2021)
"Angiotensin II (AngII)-activated epidermal growth factor receptor has been implicated in abdominal aortic aneurysm (AAA) development."3.85Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm. ( Boyer, MJ; Cooper, HA; Eguchi, S; Forrester, SJ; Hashimoto, T; Kawai, T; Kobayashi, T; Kwok, HF; Obama, T; Preston, KJ; Rizzo, V; Scalia, R; Takayanagi, T; Tsuji, T, 2017)
"Angiotensin II (Ang II) has been implicated in the development of abdominal aortic aneurysm (AAA)."3.81Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model. ( Choi, E; Daugherty, A; Eguchi, S; Elliott, KJ; Forrester, SJ; Fukuda, Y; Kawai, T; Kobayashi, T; Obama, T; Rizzo, V; Takayanagi, T; Taro, Y; Tsuji, T, 2015)
"Large animal models to study abdominal aortic aneurysms are sparse."1.51Porcine Model of Infrarenal Abdominal Aortic Aneurysm. ( Ailawadi, G; Cullen, JM; Dahl, JJ; Johnston, WF; Lu, G; Montgomery, WG; Salmon, M; Scott, EJ; Shannon, AH; Spinosa, MD; Tyerman, Z; Upchurch, GR, 2019)
"β-Aminopropionitrile (BAPN) is a compound known to cause aortic aneurysms by inhibiting lysyl oxidase, a collagen cross-linking enzyme."1.51A novel swine model of abdominal aortic aneurysm. ( Ailawadi, G; Cullen, JM; Fashandi, AZ; Johnston, WF; Lu, G; Montgomery, WG; Salmon, M; Shannon, AH; Sharma, A; Spinosa, MD; Su, G; Upchurch, GR, 2019)
"Azelnidipine treatment reduced the pathologic findings normally associated with aneurysm formation within the aortic wall."1.39Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects. ( Hirata, Y; Kitagawa, T; Kurobe, H; Matsuoka, Y; Maxfield, MW; Sata, M; Sugasawa, N, 2013)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.26)29.6817
2010's11 (57.89)24.3611
2020's7 (36.84)2.80

Authors

AuthorsStudies
Ding, YC1
Zhang, XJ1
Zhang, JX1
Zhai, ZY1
Zhang, MX1
Jiang, BH1
Berman, AG3
Romary, DJ2
Kerr, KE1
Gorazd, NE1
Wigand, MM1
Patnaik, SS1
Finol, EA1
Cox, AD1
Goergen, CJ3
Okuno, K2
Torimoto, K1
Cicalese, SM1
Hashimoto, T3
Sparks, MA1
Rizzo, V4
Eguchi, S4
Fashandi, AZ2
Spinosa, M1
Salmon, M3
Su, G4
Montgomery, W1
Mast, A1
Lu, G4
Hawkins, RB1
Cullen, JM3
Sharma, AK2
Ailawadi, G5
Upchurch, GR5
Shannon, AH2
Dahl, JJ1
Scott, EJ1
Tyerman, Z1
Spinosa, MD2
Montgomery, WG2
Johnston, WF2
Lu, H1
Sun, J1
Liang, W1
Chang, Z1
Rom, O1
Zhao, Y1
Zhao, G1
Xiong, W1
Wang, H1
Zhu, T1
Guo, Y1
Chang, L1
Garcia-Barrio, MT1
Zhang, J1
Chen, YE1
Fan, Y1
Cooper, HA2
Cicalese, S1
Preston, KJ2
Kawai, T3
Choi, ET1
Kasahara, S1
Uchida, HA1
Otaka, N1
Scalia, R2
Weiss, D2
Latorre, M1
Rego, BV1
Cavinato, C1
Tanski, BJ1
Humphrey, JD1
Takayanagi, T2
Forrester, SJ2
Obama, T2
Tsuji, T2
Kobayashi, T2
Boyer, MJ1
Kwok, HF1
Sharma, A1
Kurobe, H1
Matsuoka, Y1
Hirata, Y1
Sugasawa, N1
Maxfield, MW1
Sata, M1
Kitagawa, T1
English, SJ1
Piert, MR1
Diaz, JA1
Gordon, D1
Ghosh, A1
DʼAlecy, LG1
Whitesall, SE1
DeRoo, EP1
Watt, T1
Henke, PK1
Eliason, JL1
Fukuda, Y1
Taro, Y1
Elliott, KJ1
Choi, E1
Daugherty, A1
Imanishi, M1
Chiba, Y1
Tomita, N1
Matsunaga, S1
Nakagawa, T1
Ueno, M1
Yamamoto, K1
Tamaki, T1
Tomita, S1
Davis, JP1
Schaheen, B1
Downs, E1
Roy, RJ1
Kanematsu, Y1
Kanematsu, M1
Kurihara, C1
Tsou, TL1
Nuki, Y1
Liang, EI1
Makino, H1
Remus, EW1
O'Donnell, RE1
Rafferty, K1
Joseph, G1
Csiszar, K1
Fong, SF1
Taylor, WR1
Huffman, MD1
Curci, JA1
Moore, G1
Kerns, DB1
Starcher, BC1
Thompson, RW1

Other Studies

19 other studies available for aminopropionitrile and Abdominal Aortic Aneurysm

ArticleYear
Progression and Regression of Abdominal Aortic Aneurysms in Mice.
    Current medical science, 2021, Volume: 41, Issue:5

    Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Abdominal; Collagen; Disease Models, Animal; Disease P

2021
Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition.
    Scientific reports, 2022, 01-07, Volume: 12, Issue:1

    Topics: Administration, Topical; Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal;

2022
Smooth muscle angiotensin II type 1A receptor is required for abdominal aortic aneurysm formation induced by angiotensin II plus β-aminopropionitrile.
    Journal of molecular and cellular cardiology, 2023, Volume: 176

    Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Hum

2023
High-frequency murine ultrasound provides enhanced metrics of BAPN-induced AAA growth.
    American journal of physiology. Heart and circulatory physiology, 2019, 11-01, Volume: 317, Issue:5

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Biomechanical Phenomena;

2019
Female Mice Exhibit Abdominal Aortic Aneurysm Protection in an Established Rupture Model.
    The Journal of surgical research, 2020, Volume: 247

    Topics: Administration, Oral; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm

2020
Porcine Model of Infrarenal Abdominal Aortic Aneurysm.
    Journal of visualized experiments : JoVE, 2019, 11-21, Issue:153

    Topics: Aminopropionitrile; Angioplasty, Balloon; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Col

2019
Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB.
    Circulation, 2020, 08-04, Volume: 142, Issue:5

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Aminopropionitrile; Aneurysm, Ruptured; Angiotensin II; Animals;

2020
Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm.
    Cardiovascular research, 2021, 02-22, Volume: 117, Issue:3

    Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneu

2021
Biomechanical consequences of compromised elastic fiber integrity and matrix cross-linking on abdominal aortic aneurysmal enlargement.
    Acta biomaterialia, 2021, 10-15, Volume: 134

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; E

2021
Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 70, Issue:5

    Topics: ADAM17 Protein; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdo

2017
A novel swine model of abdominal aortic aneurysm.
    Journal of vascular surgery, 2019, Volume: 70, Issue:1

    Topics: Aminopropionitrile; Angioplasty, Balloon; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Col

2019
Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects.
    The Journal of thoracic and cardiovascular surgery, 2013, Volume: 146, Issue:6

    Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aorta, Thor

2013
Increased 18F-FDG uptake is predictive of rupture in a novel rat abdominal aortic aneurysm rupture model.
    Annals of surgery, 2015, Volume: 261, Issue:2

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Biomarker

2015
Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model.
    Clinical science (London, England : 1979), 2015, Volume: 128, Issue:9

    Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Ru

2015
Hypoxia-Inducible Factor-1α in Smooth Muscle Cells Protects Against Aortic Aneurysms-Brief Report.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:11

    Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abd

2016
A novel chronic advanced stage abdominal aortic aneurysm murine model.
    Journal of vascular surgery, 2017, Volume: 66, Issue:1

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Chronic D

2017
Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:5

    Topics: Aminopropionitrile; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, A

2010
The role of lysyl oxidase family members in the stabilization of abdominal aortic aneurysms.
    American journal of physiology. Heart and circulatory physiology, 2012, Oct-15, Volume: 303, Issue:8

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic An

2012
Functional importance of connective tissue repair during the development of experimental abdominal aortic aneurysms.
    Surgery, 2000, Volume: 128, Issue:3

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Connective Tissue; Desmos

2000