aminooxyacetic acid has been researched along with Neoplasms in 2 studies
Aminooxyacetic Acid: A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.
(aminooxy)acetic acid : A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of gamma-aminobutyric acid in tissues.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "KRas-driven cancer cells use glutaminolysis to generate the tricarboxylic acid cycle intermediate α-ketoglutarate via a transamination reaction between glutamate and oxaloacetate." | 1.72 | Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells. ( Foster, DA; Frias, MA; Hatipoglu, A; Levy, T; Menon, D, 2022) |
| "Kinetic modeling of cancer glycolysis revealed that oxamate inhibition of LDH, PYK and ENO was insufficient to achieve glycolysis flux inhibition." | 1.46 | Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism. ( Del Mazo-Monsalvo, I; Marín-Hernández, Á; Moreno-Sánchez, R; Rodríguez-Enríquez, S; Saavedra, E, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hatipoglu, A | 1 |
| Menon, D | 1 |
| Levy, T | 1 |
| Frias, MA | 1 |
| Foster, DA | 1 |
| Moreno-Sánchez, R | 1 |
| Marín-Hernández, Á | 1 |
| Del Mazo-Monsalvo, I | 1 |
| Saavedra, E | 1 |
| Rodríguez-Enríquez, S | 1 |
2 other studies available for aminooxyacetic acid and Neoplasms
| Article | Year |
|---|---|
Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells.
Topics: Adenosine Diphosphate Ribose; Aminooxyacetic Acid; ATP Citrate (pro-S)-Lyase; Glutamates; Glutamine; | 2022 |
Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism.
Topics: Aminooxyacetic Acid; Animals; Antineoplastic Agents; Cell Line, Tumor; Computer Simulation; Dichloro | 2017 |