aminooxyacetic acid has been researched along with Colorectal Neoplasms in 2 studies
Aminooxyacetic Acid: A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.
(aminooxy)acetic acid : A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of gamma-aminobutyric acid in tissues.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In colorectal and ovarian cancers, an increase in the intratumor production of hydrogen sulfide (H2S) from cystathionine β-synthase (CBS) plays an important role in promoting the cellular bioenergetics, proliferation, and migration of cancer cells." | 2.52 | The therapeutic potential of cystathionine β-synthetase/hydrogen sulfide inhibition in cancer. ( Chao, C; Coletta, C; Hellmich, MR; Szabo, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hellmich, MR | 1 |
| Coletta, C | 1 |
| Chao, C | 1 |
| Szabo, C | 1 |
| Hao, Y | 1 |
| Samuels, Y | 1 |
| Li, Q | 1 |
| Krokowski, D | 1 |
| Guan, BJ | 1 |
| Wang, C | 1 |
| Jin, Z | 1 |
| Dong, B | 1 |
| Cao, B | 1 |
| Feng, X | 1 |
| Xiang, M | 1 |
| Xu, C | 1 |
| Fink, S | 1 |
| Meropol, NJ | 1 |
| Xu, Y | 1 |
| Conlon, RA | 1 |
| Markowitz, S | 1 |
| Kinzler, KW | 1 |
| Velculescu, VE | 1 |
| Brunengraber, H | 1 |
| Willis, JE | 1 |
| LaFramboise, T | 1 |
| Hatzoglou, M | 1 |
| Zhang, GF | 1 |
| Vogelstein, B | 1 |
| Wang, Z | 1 |
1 review available for aminooxyacetic acid and Colorectal Neoplasms
| Article | Year |
|---|---|
The therapeutic potential of cystathionine β-synthetase/hydrogen sulfide inhibition in cancer.
Topics: Aminooxyacetic Acid; Animals; Antineoplastic Agents; Cell Proliferation; Colorectal Neoplasms; Cysta | 2015 |
1 other study available for aminooxyacetic acid and Colorectal Neoplasms
| Article | Year |
|---|---|
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.
Topics: Activating Transcription Factor 4; Adenocarcinoma; Adenosine Triphosphate; Aminooxyacetic Acid; Anim | 2016 |