aminooxyacetic acid has been researched along with Cardiovascular Stroke in 5 studies
Aminooxyacetic Acid: A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.
(aminooxy)acetic acid : A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of gamma-aminobutyric acid in tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aminooxyacetic acid (AOAA) is an inhibitor of aspartate aminotransferase in the aspartate-arginosuccinate shunt." | 1.56 | Aminooxyacetic acid attenuates post-infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice. ( Chen, W; Hui, J; Li, J; Pan, L; Shen, Z; Zhang, Y; Zhao, P; Zhao, Y; Zhou, W, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, P | 1 |
| Zhou, W | 1 |
| Zhang, Y | 1 |
| Li, J | 1 |
| Zhao, Y | 1 |
| Pan, L | 1 |
| Shen, Z | 1 |
| Chen, W | 1 |
| Hui, J | 1 |
| Jespersen, NR | 1 |
| Yokota, T | 1 |
| Støttrup, NB | 3 |
| Bergdahl, A | 1 |
| Paelestik, KB | 1 |
| Povlsen, JA | 1 |
| Dela, F | 1 |
| Bøtker, HE | 3 |
| Løfgren, B | 2 |
| Birkler, RD | 1 |
| Nielsen, JM | 1 |
| Wang, L | 1 |
| Caldarone, CA | 1 |
| Kristiansen, SB | 2 |
| Contractor, H | 1 |
| Johannsen, M | 1 |
| Nielsen, TT | 2 |
| González-Loyola, A | 1 |
| Barba, I | 1 |
| Kimose, HH | 1 |
| Nielsen-Kudsk, JE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cardiac Mitochondrial Function After Heart Transplantation[NCT04105803] | 64 participants (Anticipated) | Observational | 2019-04-25 | Enrolling by invitation | |||
| Cardiac Mitochondrial Function in Explanted Human Hearts[NCT04500938] | 24 participants (Anticipated) | Observational | 2020-08-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for aminooxyacetic acid and Cardiovascular Stroke
| Article | Year |
|---|---|
Aminooxyacetic acid attenuates post-infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice.
Topics: Aminooxyacetic Acid; Animals; Anti-Inflammatory Agents; Caspase 1; Heart; Heart Diseases; Interleuki | 2020 |
Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Cardiotonic Agents; Cell Respiration; Citric Acid Cycle | 2017 |
Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Cardiotonic Agents; Cell Respiration; Citric Acid Cycle | 2017 |
Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Cardiotonic Agents; Cell Respiration; Citric Acid Cycle | 2017 |
Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Cardiotonic Agents; Cell Respiration; Citric Acid Cycle | 2017 |
Inhibition of the malate-aspartate shuttle by pre-ischaemic aminooxyacetate loading of the heart induces cardioprotection.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Cardiotonic Agents; Cell Respiration; Energy Metabolism | 2010 |
Mitochondrial metabolism revisited: a route to cardioprotection.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Cardiotonic Agents; Cell Respiration; Energy Metabolism | 2010 |
Cardioprotection by L-glutamate during postischaemic reperfusion: reduced infarct size and enhanced glycogen resynthesis in a rat insulin-free heart model.
Topics: Aminooxyacetic Acid; Animals; Enzyme Inhibitors; Glutamic Acid; Glyburide; Glycogen; Hypoglycemic Ag | 2008 |