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aminooxyacetic acid and Amyotrophic Lateral Sclerosis

aminooxyacetic acid has been researched along with Amyotrophic Lateral Sclerosis in 2 studies

Aminooxyacetic Acid: A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.
(aminooxy)acetic acid : A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of gamma-aminobutyric acid in tissues.

Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spalloni, A1
Greco, V1
Ciriminna, G1
Corasolla Carregari, V1
Marini, F1
Pieroni, L1
Mercuri, NB1
Urbani, A1
Longone, P1
Mali, Y1
Zisapel, N1

Other Studies

2 other studies available for aminooxyacetic acid and Amyotrophic Lateral Sclerosis

ArticleYear
Impact of Pharmacological Inhibition of Hydrogen Sulphide Production in the SOD1G93A-ALS Mouse Model.
    International journal of molecular sciences, 2019, May-24, Volume: 20, Issue:10

    Topics: Aminooxyacetic Acid; Amyotrophic Lateral Sclerosis; Animals; Brain; Cells, Cultured; Cystathionine b

2019
VEGF up-regulation by G93A superoxide dismutase and the role of malate-aspartate shuttle inhibition.
    Neurobiology of disease, 2010, Volume: 37, Issue:3

    Topics: Aminooxyacetic Acid; Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Carbon Dioxide; Cell Lin

2010