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aminooxyacetic acid and Akinetic-Rigid Variant of Huntington Disease

aminooxyacetic acid has been researched along with Akinetic-Rigid Variant of Huntington Disease in 2 studies

Aminooxyacetic Acid: A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.
(aminooxy)acetic acid : A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of gamma-aminobutyric acid in tissues.

Research Excerpts

ExcerptRelevanceReference
"Seven patients with Huntington disease were treated with aminooxyacetic acid (AOAA), an inhibitor of gamma-aminobutyric acid aminotransferase (GABA-T), in an effort to alleviate symptoms by increasing brain GABA content."9.05Failure of aminooxyacetic acid therapy in Huntington disease. ( Allan, BM; Baird, PA; Hansen, S; MacLeod, PM; Perry, TL; Wright, JM, 1980)
"Seven patients with Huntington disease were treated with aminooxyacetic acid (AOAA), an inhibitor of gamma-aminobutyric acid aminotransferase (GABA-T), in an effort to alleviate symptoms by increasing brain GABA content."5.05Failure of aminooxyacetic acid therapy in Huntington disease. ( Allan, BM; Baird, PA; Hansen, S; MacLeod, PM; Perry, TL; Wright, JM, 1980)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Perry, TL2
Wright, JM1
Hansen, S2
Allan, BM1
Baird, PA1
MacLeod, PM1

Trials

1 trial available for aminooxyacetic acid and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Failure of aminooxyacetic acid therapy in Huntington disease.
    Neurology, 1980, Volume: 30, Issue:7 Pt 1

    Topics: Acetates; Adult; Amino Acids; Aminooxyacetic Acid; Double-Blind Method; Female; Humans; Huntington D

1980

Other Studies

1 other study available for aminooxyacetic acid and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Biochemical effects in man and rat of three drugs which can increase brain GABA content.
    Journal of neurochemistry, 1978, Volume: 30, Issue:4

    Topics: Acetates; Adult; Amino Acids; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyri

1978