aminooxyacetic acid has been researched along with Akinetic-Rigid Variant of Huntington Disease in 2 studies
Aminooxyacetic Acid: A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.
(aminooxy)acetic acid : A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of gamma-aminobutyric acid in tissues.
Excerpt | Relevance | Reference |
---|---|---|
"Seven patients with Huntington disease were treated with aminooxyacetic acid (AOAA), an inhibitor of gamma-aminobutyric acid aminotransferase (GABA-T), in an effort to alleviate symptoms by increasing brain GABA content." | 9.05 | Failure of aminooxyacetic acid therapy in Huntington disease. ( Allan, BM; Baird, PA; Hansen, S; MacLeod, PM; Perry, TL; Wright, JM, 1980) |
"Seven patients with Huntington disease were treated with aminooxyacetic acid (AOAA), an inhibitor of gamma-aminobutyric acid aminotransferase (GABA-T), in an effort to alleviate symptoms by increasing brain GABA content." | 5.05 | Failure of aminooxyacetic acid therapy in Huntington disease. ( Allan, BM; Baird, PA; Hansen, S; MacLeod, PM; Perry, TL; Wright, JM, 1980) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Perry, TL | 2 |
Wright, JM | 1 |
Hansen, S | 2 |
Allan, BM | 1 |
Baird, PA | 1 |
MacLeod, PM | 1 |
1 trial available for aminooxyacetic acid and Akinetic-Rigid Variant of Huntington Disease
Article | Year |
---|---|
Failure of aminooxyacetic acid therapy in Huntington disease.
Topics: Acetates; Adult; Amino Acids; Aminooxyacetic Acid; Double-Blind Method; Female; Humans; Huntington D | 1980 |
1 other study available for aminooxyacetic acid and Akinetic-Rigid Variant of Huntington Disease
Article | Year |
---|---|
Biochemical effects in man and rat of three drugs which can increase brain GABA content.
Topics: Acetates; Adult; Amino Acids; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyri | 1978 |