aminooxyacetic acid has been researched along with Absence Seizure in 63 studies
Aminooxyacetic Acid: A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.
(aminooxy)acetic acid : A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of gamma-aminobutyric acid in tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of drugs affecting GABA and glutamic acid receptors on theophylline-induced seizures were investigated in mice." | 7.70 | Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. ( Amabeoku, GJ, 1999) |
| " For example, injection of the "indirect" excitotoxin aminooxyacetic acid (AOAA) into the EC of rats causes behavioral seizures and preferential loss of neurons in layer III of the medial EC." | 7.70 | Ultrastructure and immunocytochemical distribution of GABA in layer III of the rat medial entorhinal cortex following aminooxyacetic acid-induced seizures. ( Eid, T; Ottersen, OP; Schwarcz, R, 1999) |
| "The effects of muscimol, aminooxyacetic acid (AOAA), diamino-n-butyric acid (DABA), baclofen, bicuculline, picrotoxin, strychnine, diazepam, phenobarbitone and phenytoin on cimetidine-induced seizures were studied in mice." | 7.68 | Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents. ( Amabeoku, GJ; Chikuni, O, 1993) |
| " The influence of some GABAergic agents on tonic seizures elicited by chloroquine was investigated in mice." | 7.68 | Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice. ( Amabeoku, G, 1992) |
| "Immature rats are more susceptible to clonic seizures induced by aminooxyacetic acid (AOAA) than mature and senile rats." | 7.68 | Age dependency of the susceptibility of rats to aminooxyacetic acid seizures. ( Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W, 1992) |
| "The effects of some GABAergic agents on seizures induced by quinine were studied in mice." | 7.68 | Effects of some GABAergic agents on quinine-induced seizures in mice. ( Amabeoku, GJ; Chikuni, O, 1992) |
| "Glutamic acid diethyl ester (GDEE) is a glutamate antagonist which acts preferentially at the quisqualate-sensitive receptor and has been shown to be an effective anticonvulsant in alcohol withdrawal and homocysteine-induced seizures but ineffective in other seizure models." | 7.67 | Inhibition of quisqualate-induced seizures by glutamic acid diethyl ester and anti-epileptic drugs. ( Freed, WJ; Schwarz, SS, 1986) |
| "Mefloquine dose dependently induced tonic seizures in mice." | 5.33 | Gamma-aminobutyric acid and mefloquine-induced seizures in mice. ( Amabeoku, GJ; Farmer, CC, 2005) |
| "AOAA also induced clonic convulsions in mice subjected to intracerebroventricular administration of the drug with a CD50 of 0." | 5.28 | Seizures induced by aminooxyacetic acid in mice: pharmacological characteristics. ( Calderazzo-Filho, LS; Cavalheiro, EA; Dziki, M; Turski, WA; Urbanska, E, 1991) |
| "These experiments suggest that seizures and neurotoxicity produced by AOAA are mediated indirectly via NMDA receptor activation." | 5.28 | Focal injection of aminooxyacetic acid produces seizures and lesions in rat hippocampus: evidence for mediation by NMDA receptors. ( Du, F; French, ED; McMaster, OG; Schwarcz, R, 1991) |
| "At higher doses the AOAA itself caused seizures even in the absence of hyperbaric oxygen." | 5.26 | Protection against high-pressure oxygen seizures by amino-oxyacetic acid. ( Beckman, DL; Iams, SG, 1978) |
| "Penicillin seizures do not cause a change in levels of GABA, but result in a decrease in glutamate within the focus." | 5.26 | Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures. ( Collins, RC; Mehta, S, 1978) |
| "The effects of drugs affecting GABA and glutamic acid receptors on theophylline-induced seizures were investigated in mice." | 3.70 | Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. ( Amabeoku, GJ, 1999) |
| " For example, injection of the "indirect" excitotoxin aminooxyacetic acid (AOAA) into the EC of rats causes behavioral seizures and preferential loss of neurons in layer III of the medial EC." | 3.70 | Ultrastructure and immunocytochemical distribution of GABA in layer III of the rat medial entorhinal cortex following aminooxyacetic acid-induced seizures. ( Eid, T; Ottersen, OP; Schwarcz, R, 1999) |
| "In the experiments carried out on Albino-Swiss mice it was found, that bilateral clamping of carotid arteries (BCCA) for 30 min produce the increase of GABA content in hippocampus, striatum and frontal cortex and decrease of the seizures susceptibility to bicuculline, investigated 7 days after surgery." | 3.69 | Influence of bilateral clamping of carotid arteries on the seizures susceptibility and central action of AOAA in mice. ( Józwiak, L; Kleinrok, Z; Sieklucka-Dziuba, M; Tokarski, R, 1996) |
| "The effects of muscimol, aminooxyacetic acid (AOAA), diamino-n-butyric acid (DABA), baclofen, bicuculline, picrotoxin, strychnine, diazepam, phenobarbitone and phenytoin on cimetidine-induced seizures were studied in mice." | 3.68 | Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents. ( Amabeoku, GJ; Chikuni, O, 1993) |
| " The influence of some GABAergic agents on tonic seizures elicited by chloroquine was investigated in mice." | 3.68 | Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice. ( Amabeoku, G, 1992) |
| "Immature rats are more susceptible to clonic seizures induced by aminooxyacetic acid (AOAA) than mature and senile rats." | 3.68 | Age dependency of the susceptibility of rats to aminooxyacetic acid seizures. ( Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W, 1992) |
| "The effects of some GABAergic agents on seizures induced by quinine were studied in mice." | 3.68 | Effects of some GABAergic agents on quinine-induced seizures in mice. ( Amabeoku, GJ; Chikuni, O, 1992) |
| "Glutamic acid diethyl ester (GDEE) is a glutamate antagonist which acts preferentially at the quisqualate-sensitive receptor and has been shown to be an effective anticonvulsant in alcohol withdrawal and homocysteine-induced seizures but ineffective in other seizure models." | 3.67 | Inhibition of quisqualate-induced seizures by glutamic acid diethyl ester and anti-epileptic drugs. ( Freed, WJ; Schwarz, SS, 1986) |
| "Seven GABAmimetic drugs, namely cetyl gamma-aminobutyric acid (cetyl GABA), 4,5,6,7-tetrahydroisoxazolo [5,4-c]pyridine-3-ol, progabide, aminooxyacetic acid, alpha-acetylenic GABA, (-)-nipecotic acid ethyl ester and (+/-)-cis-4-hydroxynipecotic acid methyl ester, were tested for their potency to block "major" (generalized clonic-tonic) seizures in gerbils, induced by blowing at the animals with compressed air." | 3.66 | High anticonvulsant potency of gamma-aminobutyric acid (GABA)mimetic drugs in gerbils with genetically determined epilepsy. ( Frey, HH; Löscher, W; Reiche, R; Schultz, D, 1983) |
| "The intramuscular injection of aminooxyacetic acid (AOAA) into mice elevated the concentration of gamma-aminobutyric acid (GABA) in the brain, inhibited glutamic acid decarboxylase activity and delayed the onset of isonicotinic acid hydrazide induced seizures." | 3.65 | A dual mechanism for the anticonvulsant action of aminooxyacetic acid. ( Peesker, SJ; Wood, JD, 1976) |
| "An attempt was made to determine the effects of genetic and temporal factors on the inhibitory action of aminooxyacetic acid on priming for audiogenic seizures." | 3.65 | Effect of aminooxyacetic acid on audiogenic seizure priming in C57BL/6J and SJL/J mice. ( Fuller, JL; Siporin, S, 1976) |
| "Mefloquine dose dependently induced tonic seizures in mice." | 1.33 | Gamma-aminobutyric acid and mefloquine-induced seizures in mice. ( Amabeoku, GJ; Farmer, CC, 2005) |
| "The interval until convulsion due to picrotoxin was also prolonged by the administration of DMP combined with diazepam and valproic acid (VPA)." | 1.31 | Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain. ( Aoyagi, Y; Ohta, A; Watanabe, Y; Yamada, K, 2001) |
| "Nitric oxide may be involved in seizure phenomena even though data often seem to be contradictory." | 1.29 | NG-nitro-L-arginine, a nitric oxide synthase inhibitor, and seizure susceptibility in four seizure models in mice. ( Borowicz, KK; Błaszczak, P; Czuczwar, SJ; Drelewska, E; Kleinrok, Z; Urbańska, EM, 1996) |
| "These experiments suggest that seizures and neurotoxicity produced by AOAA are mediated indirectly via NMDA receptor activation." | 1.28 | Focal injection of aminooxyacetic acid produces seizures and lesions in rat hippocampus: evidence for mediation by NMDA receptors. ( Du, F; French, ED; McMaster, OG; Schwarcz, R, 1991) |
| "AOAA also induced clonic convulsions in mice subjected to intracerebroventricular administration of the drug with a CD50 of 0." | 1.28 | Seizures induced by aminooxyacetic acid in mice: pharmacological characteristics. ( Calderazzo-Filho, LS; Cavalheiro, EA; Dziki, M; Turski, WA; Urbanska, E, 1991) |
| "However, lidocaine-induced convulsions were enhanced by AOAA." | 1.28 | Some correlations between local anesthetic-induced convulsions and gamma-aminobutyric acid in rat spinal cord. ( Kawaguchi, M; Ouchi, K; Sato, T; Sawaki, K, 1991) |
| "Gabapentin was administered at a dose of 23 mg/kg i." | 1.28 | Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain. ( Hönack, D; Löscher, W; Taylor, CP, 1991) |
| "In kindled rats, 31 days after the last seizure, the number of GABA-immunoreactive cells that could be observed after AOAA-treatment was significantly lower (35% ipsilateral and 25% contralateral) when compared to AOAA-treated controls." | 1.28 | Decrease in GABA immunoreactivity and alteration of GABA metabolism after kindling in the rat hippocampus. ( Huisman, E; Kamphuis, W; Lopes da Silva, FH; Wadman, WJ, 1989) |
| "The bicuculline induced convulsions were markedly potentiated during the first hour but completely blocked from 2-6 h after AOAA." | 1.27 | Aminooxyacetic acid induced accumulation of GABA in the rat brain. Interaction with GABA receptors and distribution in compartments. ( Gomes, C; Leite, JR; Pagliusi, SR; Trolin, G, 1983) |
| "The acute effects of seizures were also studied in both S/D rats and audiogenic seizure rats." | 1.27 | Effects of seizures and antiepileptic drugs on benzodiazepine receptors in rat brain. ( Laird, H; Mimaki, T; Yabuuchi, H; Yamamura, HI, 1984) |
| "Thus, the seizure-facilitating nigral efferents may be subject to inhibition by both GABA and opiates and may normally be driven by substance P." | 1.27 | Role of the substantia nigra in GABA-mediated anticonvulsant actions. ( Gale, K, 1986) |
| "3 Five min after seizure induced by the inhalant convulsant flurothyl there was no rise in GABA content in these brain regions but a similar marked degree of inhibition of GABA synthesis." | 1.27 | Inhibition of the rate of GABA synthesis in regions of rat brain following a convulsion. ( Green, AR; Metz, A; Minchin, MC; Vincent, ND, 1987) |
| "At higher doses the AOAA itself caused seizures even in the absence of hyperbaric oxygen." | 1.26 | Protection against high-pressure oxygen seizures by amino-oxyacetic acid. ( Beckman, DL; Iams, SG, 1978) |
| "The onset of convulsions induced by these convulsants coincides with the fall in GABA content and GAD activity in the mesencephalon area, and in contrast, the cessation of the convulsions by PN supplement coincides with the recovery in both the parameters." | 1.26 | Effect of antivitamin B6 on regional GABA metabolism in mouse brain and its relation to convulsions. ( Abe, M; Matsuda, M, 1979) |
| "When the convulsions were protected by pretreatment with AOAA, the decreased GABA releases in both the conditions rose to or above the normal levels." | 1.26 | Release of gamma-aminobutyric acid from isolated brain synaptosomes during semicarbazide-induced convulsions. ( Asakura, T; Hoshino, M; Matsuda, M, 1979) |
| "Phenytoin was less potent than apomorphine with GHBA or apomorphine given together with AOAA." | 1.26 | Effect of combined dopaminergic and GABA-ergic stimulation on ouabain-induced epileptiform activity. ( Kacz, D; Stach, R, 1977) |
| "Penicillin seizures do not cause a change in levels of GABA, but result in a decrease in glutamate within the focus." | 1.26 | Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures. ( Collins, RC; Mehta, S, 1978) |
| "Prominal reduced the severity of convulsions in pp'DDT-treated animals." | 1.26 | A possible neurochemical basis of the central stimulatory effects of pp'DDT. ( Jaffery, FN; Matin, MA; Siddiqui, RA, 1981) |
| "During the convulsions by TSC 16hr after the AOAA-pretreatment, the GABA content in synaptosomes was less than that from the group treated with AOAA alone, though its GABA level was higher than the normal level." | 1.26 | Relationship between gamma-aminobutyric acid metabolism and antivitamin B6-induced convulsions. ( Abe, M, 1978) |
| "Susceptibility to audiogenic seizures can be induced in some strains of resistant mice by exposure to an initial auditory stimulus (acoustic priming)." | 1.26 | Pharmacogenetic differences in audiogenic seizure priming of C57BL/6Bg and DBA/1Bg-asr mice. ( Cowen, JS; Maxson, SC; Sze, PY, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (73.02) | 18.7374 |
| 1990's | 14 (22.22) | 18.2507 |
| 2000's | 3 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DAVANZO, JP | 2 |
| MATTHEWS, RJ | 2 |
| STAFFORD, JE | 1 |
| YOENG, GA | 1 |
| WINGERSON, F | 1 |
| Amabeoku, GJ | 4 |
| Farmer, CC | 1 |
| Löscher, W | 5 |
| Vetter, M | 2 |
| Mimaki, T | 1 |
| Yabuuchi, H | 1 |
| Laird, H | 1 |
| Yamamura, HI | 1 |
| Kleinrok, Z | 4 |
| Czuczwar, SJ | 2 |
| Kozicka, M | 1 |
| Iadarola, MJ | 2 |
| Gale, K | 3 |
| Pagliusi, SR | 1 |
| Gomes, C | 1 |
| Leite, JR | 1 |
| Trolin, G | 1 |
| Frey, HH | 1 |
| Reiche, R | 1 |
| Schultz, D | 1 |
| Davison, AJ | 1 |
| Pericić, D | 1 |
| Manev, H | 1 |
| Tapia, R | 1 |
| Frieder, B | 1 |
| Karpiak, SE | 1 |
| Rapport, MM | 1 |
| Matin, MA | 2 |
| Jaffery, FN | 1 |
| Siddiqui, RA | 1 |
| Le Gal La Salle, G | 1 |
| McDonald, JW | 1 |
| Schoepp, DD | 1 |
| Chikuni, O | 2 |
| Urbańska, EM | 1 |
| Drelewska, E | 1 |
| Borowicz, KK | 1 |
| Błaszczak, P | 1 |
| Golovko, AI | 1 |
| Sofronov, GA | 1 |
| Kliuntina, TV | 1 |
| Kurganova, TA | 1 |
| Sieklucka-Dziuba, M | 1 |
| Tokarski, R | 1 |
| Józwiak, L | 1 |
| Eid, T | 1 |
| Schwarcz, R | 2 |
| Ottersen, OP | 1 |
| Yamada, K | 1 |
| Watanabe, Y | 1 |
| Aoyagi, Y | 1 |
| Ohta, A | 1 |
| Tominaga, K | 1 |
| Yamauchi, A | 1 |
| Shuto, H | 1 |
| Niizeki, M | 1 |
| Makino, K | 1 |
| Oishi, R | 1 |
| Kataoka, Y | 1 |
| Collins, RC | 1 |
| Mehta, S | 1 |
| Stach, R | 1 |
| Kacz, D | 1 |
| Stone, WE | 1 |
| Maxson, SC | 2 |
| Towle, AC | 1 |
| Sze, PY | 2 |
| Mares, P | 2 |
| Rokyta, R | 2 |
| Wood, JD | 3 |
| Russell, MP | 1 |
| Kurylo, E | 1 |
| Newstead, JD | 1 |
| György, L | 1 |
| Hoshino, M | 1 |
| Asakura, T | 1 |
| Matsuda, M | 3 |
| Abe, M | 3 |
| Yamashita, J | 1 |
| Hirata, Y | 1 |
| Beckman, DL | 1 |
| Iams, SG | 1 |
| Emson, PC | 1 |
| Cowen, JS | 1 |
| Siporin, S | 1 |
| Fuller, JL | 1 |
| Kar, PP | 1 |
| Anand, M | 1 |
| Peesker, SJ | 2 |
| Elazar, Z | 1 |
| Gottesfeld, Z | 1 |
| Lahan, GD | 1 |
| Mustapha, FB | 1 |
| Osuide, G | 1 |
| Stansfield, F | 1 |
| Ostrovskaia, RU | 1 |
| Zuboskaia, AM | 1 |
| Boĭko, SS | 1 |
| Murakami, Y | 2 |
| Murakami, K | 1 |
| Turski, W | 1 |
| Dziki, M | 2 |
| Parada, J | 1 |
| Cavalheiro, EA | 2 |
| Amabeoku, G | 1 |
| McMaster, OG | 1 |
| Du, F | 1 |
| French, ED | 1 |
| Turski, WA | 1 |
| Urbanska, E | 1 |
| Calderazzo-Filho, LS | 1 |
| Sawaki, K | 1 |
| Ouchi, K | 1 |
| Sato, T | 1 |
| Kawaguchi, M | 1 |
| Hönack, D | 1 |
| Taylor, CP | 1 |
| Paul, V | 1 |
| Krishnamoorthy, MS | 1 |
| Kamphuis, W | 1 |
| Huisman, E | 1 |
| Wadman, WJ | 1 |
| Lopes da Silva, FH | 1 |
| Zouhar, A | 1 |
| Koryntová, H | 1 |
| Marĕs, J | 1 |
| Schwarz, SS | 1 |
| Freed, WJ | 1 |
| Green, AR | 1 |
| Metz, A | 1 |
| Minchin, MC | 1 |
| Vincent, ND | 1 |
1 review available for aminooxyacetic acid and Absence Seizure
| Article | Year |
|---|---|
Cellular compartments of GABA in brain and their relationship to anticonvulsant activity.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; | 1981 |
62 other studies available for aminooxyacetic acid and Absence Seizure
| Article | Year |
|---|---|
STUDIES ON THE MECHANISM OF ACTION OF AMINOOXYACETIC ACID. I. REVERSAL OF AMINOOXYACETIC ACID-INDUCED CONVULSIONS BY VARIOUS AGENTS.
Topics: Acetates; Acetone; Aldehydes; Aminooxyacetic Acid; Antidotes; Cats; Electroencephalography; Glycine; | 1964 |
STUDIES ON THE MECHANISM OF ACTION OF AMINOOXYACETIC ACID. II. POSSIBLE PYRIDOXINE DEFICIENCY AS A MECHANISM OF ACTION OF AMINOOXYACETIC ACID TOXICITY.
Topics: Acetates; Amino Acids; Aminooxyacetic Acid; Oximes; Pharmacology; Rats; Research; Seizures; Toxicolo | 1964 |
Gamma-aminobutyric acid and mefloquine-induced seizures in mice.
Topics: Acetanilides; Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Chi-Square Distribution; Disease Mo | 2005 |
Drug-induced changes in GABA content of nerve endings in 11 rat brain regions. Correlation to pharmacological effects.
Topics: Acetates; Aminooxyacetic Acid; Animals; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric | 1984 |
Effects of seizures and antiepileptic drugs on benzodiazepine receptors in rat brain.
Topics: Acoustic Stimulation; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Cerebral Cortex; Flunitr | 1984 |
Effect of dopaminergic and GABA-ergic drugs given alone or in combination on the anticonvulsant action of phenobarbital and diphenylhydantoin in the electroshock test in mice.
Topics: Amantadine; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Baclofen; Dopamine; Electroshock | 1980 |
Aminooxyacetic acid induced accumulation of GABA in the rat brain. Interaction with GABA receptors and distribution in compartments.
Topics: 3-Mercaptopropionic Acid; Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Brain; Cell Compartme | 1983 |
High anticonvulsant potency of gamma-aminobutyric acid (GABA)mimetic drugs in gerbils with genetically determined epilepsy.
Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Diazepam; Disease Models, An | 1983 |
Relationship between drug-induced increases of GABA levels in discrete brain areas and different pharmacological effects in rats.
Topics: Aminooxyacetic Acid; Analgesics; Animals; Body Temperature; Brain Chemistry; Female; gamma-Aminobuty | 1984 |
Aminooxyacetic acid provides transient protection against seizures induced by hyperbaric oxygen.
Topics: Acetates; Aminooxyacetic Acid; Animals; Anticonvulsants; Atmospheric Pressure; Brain Chemistry; Chic | 1983 |
Effect of phenoxybenzamine on the GABA system and on convulsive activity.
Topics: Aminooxyacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; g | 1983 |
Seizure protection and increased nerve-terminal GABA: delayed effects of GABA transaminase inhibition.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Aminooxyacetic Acid; Animals; Brain; Cell Compartmenta | 1980 |
A comparative study of the pharmacology of inhibitors of GABA-metabolism.
Topics: 4-Aminobutyrate Transaminase; Aminooxyacetic Acid; Animals; Anticonvulsants; Electroshock; Ethanolam | 1980 |
Convulsions and the function of GABAergic synapses.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Cats; Electroshock; gamma-Aminobutyric Acid; Mice; Ph | 1980 |
Effect of antiepileptic drugs and an anticonvulsant on epileptiform activity induced by antibodies to ganglioside.
Topics: Action Potentials; Aminooxyacetic Acid; Animals; Anticonvulsants; Cobalt; Diazepam; Disease Models, | 1982 |
A possible neurochemical basis of the central stimulatory effects of pp'DDT.
Topics: Acetylcholine; Aminooxyacetic Acid; Ammonia; Animals; Central Nervous System; Corpus Striatum; DDT; | 1981 |
Inhibition of kindling-induced generalized seizures by aminooxyacetic acid.
Topics: Acetates; Aminooxyacetic Acid; Amygdala; Animals; Anticonvulsants; Electric Stimulation; Electroence | 1980 |
Aminooxyacetic acid produces excitotoxic brain injury in neonatal rats.
Topics: Aminooxyacetic Acid; Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Brain; Corpus | 1993 |
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cimetidine; Diazepam; Female; M | 1993 |
NG-nitro-L-arginine, a nitric oxide synthase inhibitor, and seizure susceptibility in four seizure models in mice.
Topics: Aminooxyacetic Acid; Aminophylline; Animals; Convulsants; Drug Synergism; Electroshock; Enzyme Inhib | 1996 |
[The effect of aminooxyacetic acid on the antidote activity of diazepam after exposure to GABA-lytics].
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Diazepam; Drug Interactions; GABA Agents; Male; Mice; | 1994 |
Influence of bilateral clamping of carotid arteries on the seizures susceptibility and central action of AOAA in mice.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Carotid Arteries; Femal | 1996 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cl | 1999 |
Ultrastructure and immunocytochemical distribution of GABA in layer III of the rat medial entorhinal cortex following aminooxyacetic acid-induced seizures.
Topics: Aminooxyacetic Acid; Animals; Entorhinal Cortex; gamma-Aminobutyric Acid; Immunohistochemistry; Male | 1999 |
Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Convulsants; Diazepam; | 2001 |
Ovariectomy aggravates convulsions and hippocampal gamma-aminobutyric acid inhibition induced by cyclosporin A in rats.
Topics: Aminooxyacetic Acid; Animals; Antirheumatic Agents; Cyclosporine; Dose-Response Relationship, Drug; | 2001 |
Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures.
Topics: Acetates; Alanine; Aminooxyacetic Acid; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Ani | 1978 |
Effect of combined dopaminergic and GABA-ergic stimulation on ouabain-induced epileptiform activity.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Cerebral Cortex; Drug Combinations; Drug Synergism; Elect | 1977 |
Effects of alterations in the metabolism of gamma-aminobutyrate on convulsant potencies.
Topics: 3-Mercaptopropionic Acid; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Diacetyl; Drug | 1977 |
Brain gamma-aminobutyric acid and acoustic priming in C57BL/6Bg mice.
Topics: Acoustic Stimulation; Alanine; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Brain Chem | 1977 |
Motor patterns of seizures during ontogenesis in rats [proceedings].
Topics: Aminooxyacetic Acid; Animals; Azoles; Injections, Intraperitoneal; Isoniazid; Rats; Seizures | 1979 |
Stability of synaptosomal GABA levels and their use in determining the in vivo effects of drugs: convulsant agents.
Topics: Acetates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; Hydrazines; Isoniazid; Kinet | 1979 |
Role of dopaminergic and GABA-ergic interactions in seizure susceptibility.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Dopamine; Electroshock; Female; gamma-Aminobutyric Acid; | 1979 |
Release of gamma-aminobutyric acid from isolated brain synaptosomes during semicarbazide-induced convulsions.
Topics: Aminooxyacetic Acid; Animals; Brain; Calcium; gamma-Aminobutyric Acid; Male; Mice; Potassium; Seizur | 1979 |
Effect of antivitamin B6 on regional GABA metabolism in mouse brain and its relation to convulsions.
Topics: 4-Aminobutyrate Transaminase; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; Glutamat | 1979 |
Running fit induced by injection of semicarbazide into the superior colliculus of the mouse.
Topics: Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid; Injections; Male; Mice; Pyridoxine; Ru | 1977 |
Protection against high-pressure oxygen seizures by amino-oxyacetic acid.
Topics: Acetates; Aminooxyacetic Acid; Animals; Cats; Dose-Response Relationship, Drug; Female; Hyperbaric O | 1978 |
Relationship between gamma-aminobutyric acid metabolism and antivitamin B6-induced convulsions.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminooxyacetic Acid; Animals; Brain; gamma-Aminobutyric Acid | 1978 |
Effects of chronic treatment with amino-oxyacetic acid or sodium n-dipropylacetate on brain GABA levels and the development and regression of cobalt epileptic foci in rats.
Topics: 4-Aminobutyrate Transaminase; Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Brain C | 1976 |
Pharmacogenetic differences in audiogenic seizure priming of C57BL/6Bg and DBA/1Bg-asr mice.
Topics: Acoustic Stimulation; Aminooxyacetic Acid; Animals; Brain Chemistry; Cycloheximide; Female; gamma-Am | 1977 |
Effect of aminooxyacetic acid on audiogenic seizure priming in C57BL/6J and SJL/J mice.
Topics: Acetates; Acoustic Stimulation; Aminooxyacetic Acid; Animals; Female; Male; Mice; Mice, Inbred C57BL | 1976 |
Modification of pp' DDT induced convulsions by changes in the level of cerebral gamma-aminobutyric acid in mice.
Topics: Aminobutyrates; Aminooxyacetic Acid; Ammonia; Animals; Brain; DDT; gamma-Aminobutyric Acid; Hydroxyl | 1976 |
A dual mechanism for the anticonvulsant action of aminooxyacetic acid.
Topics: Acetates; Allyl Compounds; Aminooxyacetic Acid; Animals; Anticonvulsants; Behavior, Animal; Brain Ch | 1976 |
Effect of drug-induced increase of brain GABA levels on penicillin focus.
Topics: Acetates; Action Potentials; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain Chemistry; Cats; Ce | 1975 |
The anticonvulsant action of GABA-elevating agents: a re-evaluation.
Topics: Allyl Compounds; Aminobutyrates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Drug Evaluati | 1975 |
Proceedings: The effect of benzaldoxime-oxyacetic acid on electrically induced seizures in young chicks.
Topics: Acetates; Aminooxyacetic Acid; Animals; Animals, Newborn; Chickens; Female; Male; Oximes; Seizures | 1975 |
[Antagonistic effect of sodium hydroxybutyrate on several effects of aminoxyacetic acid].
Topics: Acetates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Hydroxybuty | 1975 |
Anticonvulsant activity of aminooxyacetic acid on convulsions induced by thiosemicarbazide.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; gamma-Aminobutyric A | 1976 |
The effect of castrix (2-chloro-4- dimethylamino-6-methylpyrimidine) on the distribution of B6 vitamers in mouse brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Isoniazid; Male; Mice; Penicillamine; Pyridoxa | 1976 |
Effects of some GABAergic agents on quinine-induced seizures in mice.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Diazepam; Male; Mice; Mice, Inb | 1992 |
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures.
Topics: Aging; Aminooxyacetic Acid; Animals; Anticonvulsants; Body Temperature; Brain; Carbamazepine; Clonaz | 1992 |
Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Chloroquine; Diazepam; gamma-Aminobutyric Ac | 1992 |
Focal injection of aminooxyacetic acid produces seizures and lesions in rat hippocampus: evidence for mediation by NMDA receptors.
Topics: Aminooxyacetic Acid; Animals; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-A | 1991 |
Seizures induced by aminooxyacetic acid in mice: pharmacological characteristics.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Cerebral Cortex; Cerebral Ventricles; Diazepam | 1991 |
Some correlations between local anesthetic-induced convulsions and gamma-aminobutyric acid in rat spinal cord.
Topics: Aminooxyacetic Acid; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyr | 1991 |
Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain.
Topics: Acetates; Amines; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxy | 1991 |
Synergistic anticonvulsant action of diazepam & clonazepam with amino-oxyacetic acid against isoniazid-induced convulsions in rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Clonazepam; Diazepam; Drug Therapy, Combination; Isoniazid; | 1989 |
Decrease in GABA immunoreactivity and alteration of GABA metabolism after kindling in the rat hippocampus.
Topics: Aminooxyacetic Acid; Animals; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Rats | 1989 |
EEG changes induced by convulsants interfering with GABAergic inhibition in rats. I. Cortical recordings.
Topics: 3-Mercaptopropionic Acid; Acetates; Aminooxyacetic Acid; Animals; Bicuculline; Cerebral Cortex; Elec | 1985 |
Role of the substantia nigra in GABA-mediated anticonvulsant actions.
Topics: Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Brain Diseases; Denervation; D | 1986 |
Inhibition of quisqualate-induced seizures by glutamic acid diethyl ester and anti-epileptic drugs.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Carbamazepine; Diazepam; Female; Glutamates; Mice; Ox | 1986 |
Inhibition of the rate of GABA synthesis in regions of rat brain following a convulsion.
Topics: Aminooxyacetic Acid; Animals; Brain; Flurothyl; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spe | 1987 |