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aminolevulinic acid and Vulvar Neoplasms

aminolevulinic acid has been researched along with Vulvar Neoplasms in 28 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Vulvar Neoplasms: Tumors or cancer of the VULVA.

Research Excerpts

ExcerptRelevanceReference
"We present one case of vulvar extramammary Paget's disease (EMPD), that is a female patient with lesions in the vulva and involving the urethra."1.91Efficacy of hematoporphyrin injection (HpD) photodynamic therapy in the treatment of widespread extramammary Paget's disease. ( Li, Y; Liu, R; Liu, X; Ma, G; Ma, T; Tang, Y; Xiang, X, 2023)
"Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer."1.35[Photodynamic therapy in vulvar intraepithelial neoplasia]. ( Biniszkiewicz, T; Kellas-Sleczka, S; Kozak-Darmas, I; Olejek, A; Sieroń, A, 2008)
"In the present study, five patients with extramammary Paget's disease with a total of eight lesions first underwent carbon dioxide (CO2) laser abrasion, followed by 3 h of occlusive application of aminolaevulinic acid (ALA) and then 100 J/cm2 irradiation with a 630-nm excimer dye laser."1.35Photodynamic therapy following carbon dioxide laser enhances efficacy in the treatment of extramammary Paget's disease. ( Fukui, T; Matsumoto, Y; Tamada, Y; Watanabe, D, 2009)
"In this study, we have assessed: (a) HPV infection; (b) HLA expression; and (c) immune infiltrating cells in VIN biopsies from responders and nonresponders to determine whether these factors may limit response to topical 5-aminolevulinic acid-based PDT."1.31Immunological and viral factors associated with the response of vulval intraepithelial neoplasia to photodynamic therapy. ( Abdel-Hady, ES; Corbitt, G; Duggan-Keen, M; Hampson, IN; Kitchener, HC; Martin-Hirsch, P; Moore, JV; Stern, PL, 2001)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.14)18.2507
2000's15 (53.57)29.6817
2010's7 (25.00)24.3611
2020's4 (14.29)2.80

Authors

AuthorsStudies
Mossakowska, BJ1
Shahmoradi Ghahe, S1
Cysewski, D1
Fabisiewicz, A1
Tudek, B1
Siedlecki, JA1
Xiang, X1
Li, Y1
Tang, Y1
Liu, R1
Ma, T1
Liu, X1
Ma, G1
Iwai, Y1
Fujiwara, H1
Zhao, S1
Liu, D1
Shi, W1
Kang, Y1
Li, Q1
Liu, Q1
Chen, M1
Li, F1
Su, J1
Zhang, Y1
Wu, L1
Leufflen, L1
Francois, A1
Salleron, J1
Barlier, C1
Dolivet, G1
Marchal, F1
Bezdetnaya, L1
Rioli, DI1
Samimi, M1
Beneton, N1
Hainaut, E1
Martin, L1
Misery, L1
Quereux, G1
Fontanelli, R2
Papadia, A1
Martinelli, F1
Lorusso, D1
Grijuela, B1
Merola, M1
Solima, E2
Ditto, A2
Raspagliesi, F2
Maździarz, A1
Zielińska, A1
Alkhalayla, H1
Spiewankiewicz, B2
Vicentini, C1
Carpentier, O1
Lecomte, F1
Thecua, E1
Mortier, L1
Mordon, SR1
Olejek, A2
Kozak-Darmas, I1
Biniszkiewicz, T2
Kellas-Sleczka, S1
Sieroń, A2
Fukui, T1
Watanabe, D1
Tamada, Y1
Matsumoto, Y1
Zawislak, A1
Donnelly, RF2
McCluggage, WG2
Price, JH2
McClelland, HR2
Woolfson, AD2
Dobbs, S1
Maxwell, P1
McCarron, PA3
Ballester, I1
Belinchón, I1
Guijarro, J1
Oltra, F1
Toledo, F1
Cuesta, L1
Daayana, S1
Winters, U1
Stern, PL2
Kitchener, HC3
Akoel, KM1
Welfel, J1
Gottwald, L1
Suzin, J1
Zawislak, AA2
Dobbs, SP1
Nowakowski, Z1
Stelmachów, J1
Gerulewicz, G1
Hillemanns, P2
Wang, X1
Staehle, S1
Michels, W1
Dannecker, C2
Ma, LW1
Juzenas, P1
Lani, V1
Woolfson, A1
Moan, J1
Rossi, G1
Hanozet, F1
Kusamura, S1
Martin-Hirsch, PL1
Whitehurst, C1
Buckley, CH1
Moore, JV2
Henta, T1
Itoh, Y1
Kobayashi, M1
Ninomiya, Y1
Ishibashi, A1
Untch, M1
Baumgartner, R1
Stepp, H1
Diebold, J1
Weingandt, H1
Pröve, F1
Korell, M1
Kurwa, HA1
Barlow, RJ1
Neill, S1
Fehr, MK2
Hornung, R2
Schwarz, VA2
Simeon, R1
Haller, U2
Wyss, P2
Urban, A1
Drebkowski, A1
Abdel-Hady, ES1
Martin-Hirsch, P1
Duggan-Keen, M1
Corbitt, G1
Hampson, IN1
Degen, A1
Fink, D1

Reviews

2 reviews available for aminolevulinic acid and Vulvar Neoplasms

ArticleYear
Clinical and immunological response to photodynamic therapy in the treatment of vulval intraepithelial neoplasia.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2011, Volume: 10, Issue:5

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Papillomaviridae; Papillomavirus Infections;

2011
[Use of photodynamic methods in diagnosis and therapy of epithelial vulvar diseases].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2000, Volume: 53, Issue:9-10

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Condylomata Acuminata; Female; Humans; Photochemotherapy; Ph

2000

Trials

7 trials available for aminolevulinic acid and Vulvar Neoplasms

ArticleYear
Photodynamic therapy with M-ALA as non surgical treatment option in patients with primary extramammary Paget's disease.
    Gynecologic oncology, 2013, Volume: 130, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Middle Aged; Paget Disease, Extramamma

2013
Comparison of efficiency of photodynamic diagnostics with topical use of the 3% and 15% aminolevulinic acid in the detection of vulvar lesions.
    Photodiagnosis and photodynamic therapy, 2013, Volume: 10, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Dose-Response Relationship, Drug; Female;

2013
Clinical and immunohistochemical assessment of vulval intraepithelial neoplasia following photodynamic therapy using a novel bioadhesive patch-type system loaded with 5-aminolevulinic acid.
    Photodiagnosis and photodynamic therapy, 2009, Volume: 6, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Drug Carriers; Female; Humans; Middle Age

2009
Facilitated delivery of ALA to inaccessible regions via bioadhesive patch systems.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2006, Volume: 25, Issue:1-2

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma in Situ; Drug Delivery Systems; Female; Herp

2006
Photodynamic therapy using a methyl ester of 5-aminolevulinic acid in recurrent Paget's disease of the vulva: a pilot study.
    Gynecologic oncology, 2006, Volume: 103, Issue:2

    Topics: Aged; Aminolevulinic Acid; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Paget Disease, E

2006
Photodynamic therapy of vulvar intraepithelial neoplasia using 5-aminolevulinic acid.
    International journal of cancer, 2000, Mar-01, Volume: 85, Issue:5

    Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Middle Aged; Photochemotherapy;

2000
Photodynamic therapy of vulvar intraepithelial neoplasia III using topically applied 5-aminolevulinic acid.
    Gynecologic oncology, 2001, Volume: 80, Issue:1

    Topics: Administration, Topical; Adult; Aminolevulinic Acid; Carcinoma in Situ; Disease-Free Survival; Feasi

2001

Other Studies

19 other studies available for aminolevulinic acid and Vulvar Neoplasms

ArticleYear
Mechanisms of Resistance to Photodynamic Therapy (PDT) in Vulvar Cancer.
    International journal of molecular sciences, 2022, Apr-08, Volume: 23, Issue:8

    Topics: Aminolevulinic Acid; Female; Heme; Humans; Photochemotherapy; Photosensitizing Agents; Protoporphyri

2022
Efficacy of hematoporphyrin injection (HpD) photodynamic therapy in the treatment of widespread extramammary Paget's disease.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 42

    Topics: Aminolevulinic Acid; Female; Hematoporphyrin Derivative; Hematoporphyrins; Humans; Paget Disease, Ex

2023
Fluorescence imaging of lymphangioma circumscriptum of the vulva with aminolevulinic acid and target-type narrow band ultraviolet light.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 43

    Topics: Aminolevulinic Acid; Female; Humans; Lymphangioma; Optical Imaging; Photochemotherapy; Photosensitiz

2023
Efficacy of a New Therapeutic Option for Vulvar Intraepithelial Neoplasia: Superficial Shaving Combined With Photodynamic Therapy.
    Lasers in surgery and medicine, 2020, Volume: 52, Issue:6

    Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Middle Aged; Patient Satisfaction; Ph

2020
Photodynamic diagnosis with methyl-5-aminolevulinate in squamous intraepithelial lesions of the vulva: Experimental research.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Cell Line; Computer Systems; Female; Hetero

2018
Efficacy and tolerance of photodynamic therapy for vulvar Paget's disease: a multicentric retrospective study.
    European journal of dermatology : EJD, 2018, Jun-01, Volume: 28, Issue:3

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Follow-Up Studies; Humans; Middle Aged; Neopla

2018
Treatment of a vulvar Paget's disease by photodynamic therapy with a new light emitting fabric based device.
    Lasers in surgery and medicine, 2017, Volume: 49, Issue:2

    Topics: Aminolevulinic Acid; Female; Humans; Middle Aged; Paget Disease, Extramammary; Photochemotherapy; Ph

2017
[Photodynamic therapy in vulvar intraepithelial neoplasia].
    Ginekologia polska, 2008, Volume: 79, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Dis

2008
Photodynamic therapy following carbon dioxide laser enhances efficacy in the treatment of extramammary Paget's disease.
    Acta dermato-venereologica, 2009, Volume: 89, Issue:2

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Combined Modality Therapy; Female; Humans; Lasers, Exc

2009
Photodynamic therapy of vulvar intraepithelial neoplasia using methyl aminolevulinate.
    The Journal of dermatological treatment, 2012, Volume: 23, Issue:2

    Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Photochemotherapy; Photosensitizing A

2012
[Photodynamic diagnosis of vulvar precancerous conditions and invasive cancers using 5-aminolevulinic acid].
    Ginekologia polska, 2003, Volume: 74, Issue:9

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Diagnostic Techniques, Obstetrical and Gynecological; Female

2003
Successful photodynamic therapy of vulval Paget's disease using a novel patch-based delivery system containing 5-aminolevulinic acid.
    BJOG : an international journal of obstetrics and gynaecology, 2004, Volume: 111, Issue:10

    Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Female; Humans; Paget Disease, Extramammary; P

2004
Diagnostic value of the PDD method in evaluation of vulvar lesions.
    European journal of gynaecological oncology, 2005, Volume: 26, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; Female; Humans; Microscopy; Middle Aged; Photochemotherapy; Photos

2005
Evaluation of different treatment modalities for vulvar intraepithelial neoplasia (VIN): CO(2) laser vaporization, photodynamic therapy, excision and vulvectomy.
    Gynecologic oncology, 2006, Volume: 100, Issue:2

    Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Gynecologic Surgical Procedures; Humans; Lase

2006
Photodynamic treatment for lower genital tract intraepithelial neoplasia.
    Lancet (London, England), 1998, May-09, Volume: 351, Issue:9113

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Photochemotherapy; Photosensitizing Agents;

1998
Photodynamic therapy for inoperable vulval Paget's disease using delta-aminolaevulinic acid: successful management of a large skin lesion.
    The British journal of dermatology, 1999, Volume: 141, Issue:2

    Topics: Aged; Aminolevulinic Acid; Female; Humans; Paget Disease, Extramammary; Photochemotherapy; Photosens

1999
Single-episode photodynamic therapy and vulval intraepithelial neoplasia type III resistant to conventional therapy.
    The British journal of dermatology, 2000, Volume: 143, Issue:5

    Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Photochemotherapy; Photosensitizing A

2000
Immunological and viral factors associated with the response of vulval intraepithelial neoplasia to photodynamic therapy.
    Cancer research, 2001, Jan-01, Volume: 61, Issue:1

    Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes

2001
Photodynamic therapy of vulvar and vaginal condyloma and intraepithelial neoplasia using topically applied 5-aminolevulinic acid.
    Lasers in surgery and medicine, 2002, Volume: 30, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aminolevulinic Acid; Condylomata Acuminata; Female

2002