aminolevulinic acid has been researched along with Tuberous Sclerosis in 2 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The facial angiofbromas due to tuberous sclerosis complex produced significant social and emotional distress for affected individuals, but there is no specific therapeutic strategy up to now." | 1.51 | Photodynamic therapy in a patient with facial angiofibromas due to tuberous sclerosis complex. ( Chen, P; Guo, J; He, S; Jiang, L; Li, C; Li, Q; Li, S; Peng, X; Shi, M; Wang, Q; Zeng, K; Zhu, M, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, M | 1 |
| He, S | 1 |
| Chen, P | 1 |
| Li, Q | 1 |
| Zhu, M | 1 |
| Guo, J | 1 |
| Jiang, L | 1 |
| Wang, Q | 1 |
| Peng, X | 1 |
| Li, S | 1 |
| Li, C | 1 |
| Zeng, K | 1 |
| Weinberger, CH | 1 |
| Endrizzi, B | 1 |
| Hook, KP | 1 |
| Lee, PK | 1 |
2 other studies available for aminolevulinic acid and Tuberous Sclerosis
| Article | Year |
|---|---|
Photodynamic therapy in a patient with facial angiofibromas due to tuberous sclerosis complex.
Topics: Adolescent; Aminolevulinic Acid; Angiofibroma; Facial Neoplasms; Humans; Male; Microwaves; Photochem | 2019 |
Treatment of angiofibromas of tuberous sclerosis with 5-aminolevulinic acid blue light photodynamic therapy followed by immediate pulsed dye laser.
Topics: Adolescent; Adult; Aminolevulinic Acid; Angiofibroma; Child; Combined Modality Therapy; Facial Neopl | 2009 |