Page last updated: 2024-10-16

aminolevulinic acid and Skin Diseases

aminolevulinic acid has been researched along with Skin Diseases in 88 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Skin Diseases: Diseases involving the DERMIS or EPIDERMIS.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy and safety of LPDL alone versus LPDL in photodynamic therapy with methylaminolevulinic acid (MAL-LPDL) for acne vulgaris."5.13Long-pulsed dye laser versus long-pulsed dye laser-assisted photodynamic therapy for acne vulgaris: A randomized controlled trial. ( Haedersdal, M; Togsverd-Bo, K; Wiegell, SR; Wulf, HC, 2008)
"A literature review and results of new clinical trials with regards to photorejuvenation and acne vulgaris treatments with 5-aminolevulinic acid photodynamic therapy are presented."4.825-aminolevulinic acid photodynamic therapy: where we have been and where we are going. ( Gold, MH; Goldman, MP, 2004)
"Short-contact, full-face 5-aminolevulinic acid photodynamic therapy treatments with a variety of lasers and light sources have shown to be successful in treating all facets of photorejuvenation and the associated actinic keratoses as well as disorders of sebaceous glands, including acne vulgaris."4.825-aminolevulinic acid photodynamic therapy: where we have been and where we are going. ( Gold, MH; Goldman, MP, 2004)
"In order to evaluate the possible therapeutical effects of reduced glutathione in subjects affected by acquired or congenital heme biosynthesis alterations, two groups of subjects have been considered: the first, of 5 subjects with abnormal lead absorption, the second of 10 patients suffering from porphyria cutanea tarda (PCT)."3.68[Evaluation of the effects of reduced glutathione in subjects with acquired and congenital changes in heme biosynthesis]. ( Alessio, L; Buizza, P; De Panfilis, G; De Vincentiis, A; Ferioli, A; Leali, C; Pasolini, G, 1992)
" Over the following 2 years, some investigators noted and formally reported the continued occurrence of serious adverse events in excess of those described with other approved cutaneous PDT treatments."2.79Prolonged adverse events following photodynamic therapy: regulatory implications. ( Anderson, SJ; Dixon, AJ; Mazzurco, JD; Steinman, HK, 2014)
" It is of concern that this ALA product and lamp could be promoted and used widely in Australia following these reports of significant adverse events and continued lack of TGA approval."2.79Prolonged adverse events following photodynamic therapy: regulatory implications. ( Anderson, SJ; Dixon, AJ; Mazzurco, JD; Steinman, HK, 2014)
"Development of new skin cancers."2.79Prolonged adverse events following photodynamic therapy: regulatory implications. ( Anderson, SJ; Dixon, AJ; Mazzurco, JD; Steinman, HK, 2014)
"The efficacy for lichenoid dermatoses was dependent on the clinical variant (erosive and scleroatrophic were more responsive than hypertrophic)."2.78A retrospective analysis of real-life practice of off-label photodynamic therapy using methyl aminolevulinate (MAL-PDT) in 20 Italian dermatology departments. Part 1: inflammatory and aesthetic indications. ( Aronson, E; Calzavara-Pinton, PG; Rossi, MT; Sala, R, 2013)
"The non-acute porphyrias are porphyria cutanea tarda, erythropoietic protoporphyria, X-linked protoporphyria, and the rare congenital erythropoietic porphyria."2.61Clinical Guide and Update on Porphyrias. ( Doss, MO; Schuppan, D; Stölzel, U, 2019)
"Aminolevulinic acid is a prodrug that is metabolized intracellularly to form the photosensitizing molecule protoporphyrin IX (PpIX)."2.42Photodynamic therapy and topical aminolevulinic acid: an overview. ( Gupta, AK; Ryder, JE, 2003)
"Photodynamic therapy (PDT) for cancer patients has developed into an important new clinical treatment modality in the past 25-years."2.405-Aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges. ( Berg, K; Giercksky, KE; Kongshaug, M; Moan, J; Nesland, JM; Peng, Q; Warloe, T, 1997)
"5-aminolevulinic acid is an early intermediate product in the synthesis of heme."2.40[Use of 5-aminolevulinic acid in photochemotherapy and fluorescence diagnostics]. ( Bech, O; Berg, K; Moan, J; Peng, Q, 1998)
"5-Aminolevulinic acid (5-ALA) is a crucial precursor of heme, which is essential for CII, complex III, complex IV (CIV) and cytochrome c activities."1.915-Aminolevulinic acid bypasses mitochondrial complex I deficiency and corrects physiological dysfunctions in Drosophila. ( Ando, K; Asada, A; Ishii, T; Ishizuka, M; Noguchi, M; Nozawa, N; Saito, T; Shinno, K; Takahashi, K, 2023)
"Methyl nicotinate (MN) is a thermogenic and vasodilating substance that facilitates the topical tissue penetration of some compounds."1.56MAL-associated methyl nicotinate for topical PDT improvement. ( Bagnato, VS; Buzza, HH; Ciol, H; Inada, NM; Leite, IS; Romano, RA; Stringasci, MD, 2020)
"Sarcoidosis is a systemic granulomatous disease."1.35Photodynamic therapy as an alternative treatment for cutaneous sarcoidosis. ( Bieber, T; Novak, N; Wilsmann-Theis, D, 2008)
"The main adverse effect in PDT treatment is pain."1.34Pain and photodynamic therapy. ( Brogaard, HM; Jemec, GB; Lindeburg, KE, 2007)
" at the dosage of 600-1200 mg for a variable period of 3-5 days in the first group, for 7-10 days in the patients with PCT."1.28[Evaluation of the effects of reduced glutathione in subjects with acquired and congenital changes in heme biosynthesis]. ( Alessio, L; Buizza, P; De Panfilis, G; De Vincentiis, A; Ferioli, A; Leali, C; Pasolini, G, 1992)
"The porphyrias are caused by hereditary defects in the synthesis of heme."1.27The porphyrias. ( Rosen, T; Sekula, SA; Tschen, JA, 1986)

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-199010 (11.36)18.7374
1990's5 (5.68)18.2507
2000's34 (38.64)29.6817
2010's31 (35.23)24.3611
2020's8 (9.09)2.80

Authors

AuthorsStudies
do Amparo Manoel, C1
de Sousa Mariano, S1
da Silva Ramos, E1
Paolillo, FR1
de Aro, AA1
Mendes, C1
Venturini, LM1
Silveira, PCL1
Bagnato, VS2
de Andrade, TAM1
Mackay, AM1
Yu, Y1
Li, J2
Zou, Y1
Yin, R1
Nozawa, N1
Noguchi, M1
Shinno, K1
Saito, T2
Asada, A1
Ishii, T1
Takahashi, K1
Ishizuka, M1
Ando, K1
Bhatia, N1
Monfrecola, G1
Megna, M1
Rovati, C1
Arisi, M2
Rossi, M1
Calzavara-Pinton, I1
Fabbrocini, G1
Calzavara-Pinton, P2
Stringasci, MD1
Ciol, H1
Romano, RA1
Buzza, HH1
Leite, IS1
Inada, NM1
Liu, D1
Zhao, S1
Chen, M1
Wu, L1
Dalal, KS1
Bridgeman, MB1
Wen, X1
Li, Y1
Hamblin, MR1
Theresia, C1
Zheng, J1
Chen, XY1
Alique-García, S1
Company-Quiroga, J1
Horcajada-Reales, C1
Echeverría-García, B1
Tardío-Dovao, JC1
Borbujo, J1
Siegel, DM1
Nguyen, K1
Khachemoune, A1
Lim, CM1
Grillo, M1
Harrison, P1
Nguyen, AM1
Gordon, L1
Stölzel, U1
Doss, MO1
Schuppan, D1
Basset-Seguin, N3
Anderson, SJ1
Steinman, HK1
Mazzurco, JD1
Dixon, AJ1
Wang, D1
Liang, J1
Xu, J1
Chen, L1
Kürten, V1
Neumann, NJ2
Frank, J1
Haedersdal, M2
Erlendsson, AM1
Paasch, U1
Anderson, RR2
Juhasz, ML1
Levin, MK1
Marmur, ES1
Wilsmann-Theis, D1
Bieber, T1
Novak, N1
Yang, J1
Xia, Y1
Liu, X1
Jiang, S1
Xiong, L1
Piergiacomo, CP1
Mariachiara, A1
Sereni, E1
Elena, S1
Ortel, B1
Bernhard, O1
O'Neill, J1
Fien, S1
Zeitouni, NC1
Tyrrell, JS1
Campbell, SM1
Curnow, A2
Li, Q1
Jiao, B1
Long, HA1
Penrose, C1
Mercer, SE1
Shim-Chang, H1
Oh, EK1
Jin, SE1
Kim, JK1
Park, JS1
Park, Y1
Kim, CK1
Tyrrell, J1
Thorn, C1
Shore, A1
Campbell, S1
Hasegawa, T1
Suga, Y1
Mizuno, Y1
Haruna, K1
Ikeda, S1
Moore, MM1
Reyna, C1
Hope, RH1
Ibbotson, S2
Gomes, J1
Ventura, F1
da Luz Duarte, M1
Brito, C1
Li, X1
Zhou, ZP1
Hu, L1
Zhang, WJ1
Li, W1
Dragicevic-Curic, N1
Fahr, A1
Calzavara-Pinton, PG3
Rossi, MT2
Aronson, E1
Sala, R3
Valentine, RM1
Ibbotson, SH2
Wood, K1
Brown, CT1
Moseley, H2
Gupta, AK1
Ryder, JE1
Kormeili, T1
Yamauchi, PS1
Lowe, NJ1
Gold, MH2
Goldman, MP1
Akita, Y1
Kozaki, K1
Nakagawa, A1
Ito, S1
Tamada, Y2
Fujiwara, S1
Nishikawa, N1
Uchida, K1
Yoshikawa, K1
Noguchi, T1
Miyaishi, O1
Shimozato, K1
Saga, S1
Matsumoto, Y2
Thissen, MR1
Kuijpers, DI1
Neumann, HA1
Larkö, O1
Wennberg, AM2
Foley, P3
Fergin, P1
Takeda, H1
Kaneko, T1
Harada, K1
Matsuzaki, Y1
Nakano, H1
Hanada, K1
Mikasa, K1
Watanabe, D1
Kondo, C1
Bäumler, W1
Ackermann, G1
Abels, C2
Szeimies, RM4
Gilaberte, Y1
Serra-Guillén, C1
de las Heras, ME1
Ruiz-Rodríguez, R1
Fernández-Lorente, M1
Benvenuto-Andrade, C1
González-Rodríguez, S1
Guillén-Barona, C1
Silva, JN1
Filipe, P1
Morlière, P1
Mazière, JC1
Freitas, JP1
Cirne de Castro, JL1
Santus, R1
Bryld, LE1
Jemec, GB2
Biron, J1
Ghaffar, SA1
Clements, SE1
Lear, JT1
Braathen, LR1
Bissonnette, R1
Pariser, D1
Roelandts, R1
Morton, CA3
Venturini, M1
Lindeburg, KE1
Brogaard, HM1
Redbord, KP1
Hanke, CW1
Togsverd-Bo, K1
Wiegell, SR1
Wulf, HC1
Ibraham, NG1
Friedland, ML1
Levere, RD1
Bissell, DM1
Stewart, PM1
Hensley, WJ1
Romeo, G1
Waldenström, J1
Magnin, PH1
del C Batlle, AM1
de Xifra, EA1
Lenczner, M1
Parera, VE1
Stella, AM1
Hines, JD1
Peng, Q2
Warloe, T1
Berg, K2
Moan, J2
Kongshaug, M1
Giercksky, KE1
Nesland, JM1
Fritsch, C2
Goerz, G1
Ruzicka, T2
Bech, O1
Dierickx, CC1
Goldenhersh, M1
Dwyer, P1
Stratigos, A1
Mihm, M1
Lehmann, P1
Fischer, F1
Dickson, EF1
Pottier, RH1
Wieland, H1
Brown, SB2
Collins, S1
Jenkinson, H1
Kurwa, H1
Langmack, K1
McKenna, K1
Pearse, AD1
Stringer, M1
Taylor, DK1
Wong, G1
Rhodes, LE1
Karrer, S2
Wimmershoff, MB1
Landthaler, M2
Taylor, EL1
Ferioli, A1
De Vincentiis, A1
Buizza, P1
Pasolini, G1
Leali, C1
De Panfilis, G1
Alessio, L1
Sekula, SA1
Tschen, JA1
Rosen, T1
Chan, KM1
Ladenson, JH1
Vaidya, HC1
Kanan, R1
Siepker, LJ1
Kramer, S1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Fluorescence and Thermal Imaging of the Skin Before and During Photodynamic Therapy[NCT03167762]18 participants (Actual)Interventional2017-06-22Completed
Evaluation of the Formulation of 5-aminolevulinic Acid With Dimethylsulfoxide in Photodynamic Therapy for Treatment of Actinic Keratosis[NCT01459393]Phase 3137 participants (Actual)Interventional2010-11-30Completed
A Randomized Half-side Comparative Trial of Fractional Laser-assisted Daylight Photodynamic Therapy Versus Daylight Photodynamic Therapy in Organ Transplant Recipients With Multiple Actinic Keratoses of the Scalp or Forehead[NCT01898936]12 participants (Actual)Interventional2013-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

38 reviews available for aminolevulinic acid and Skin Diseases

ArticleYear
The evolution of clinical guidelines for antimicrobial photodynamic therapy of skin.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2022, Volume: 21, Issue:3

    Topics: Aminolevulinic Acid; Anti-Bacterial Agents; Humans; Photochemotherapy; Photosensitizing Agents; Skin

2022
The Interventions to Minimize Pain During Photodynamic Therapy With 5-Aminolevulinic Acid for the Treatment of Cutaneous Diseases.
    Journal of drugs in dermatology : JDD, 2023, Nov-01, Volume: 22, Issue:11

    Topics: Aminolevulinic Acid; Humans; Levulinic Acids; Pain; Photochemotherapy; Skin Diseases; United States

2023
A Critical Reappraisal of Off-Label Use of Photodynamic Therapy for the Treatment of Non-Neoplastic Skin Conditions.
    Dermatology (Basel, Switzerland), 2021, Volume: 237, Issue:2

    Topics: Acne Vulgaris; Aminolevulinic Acid; Cosmetic Techniques; Humans; Lichen Sclerosus et Atrophicus; Off

2021
The application of physical pretreatment in photodynamic therapy for skin diseases.
    Lasers in medical science, 2021, Volume: 36, Issue:7

    Topics: Aminolevulinic Acid; Humans; Keratosis, Actinic; Neoplasm Recurrence, Local; Photochemotherapy; Phot

2021
Photodynamic therapy in dermatology beyond non-melanoma cancer: An update.
    Photodiagnosis and photodynamic therapy, 2017, Volume: 19

    Topics: Acne Vulgaris; Aminolevulinic Acid; Collagen; Humans; Photochemotherapy; Photosensitizing Agents; Po

2017
Topical ALA-PDT as alternative therapeutic option in treatment-recalcitrant dermatosis: Report of 4 cases.
    Photodiagnosis and photodynamic therapy, 2017, Volume: 20

    Topics: Acne Vulgaris; Adolescent; Adult; Aged, 80 and over; Aminolevulinic Acid; Condylomata Acuminata; Fem

2017
An update on topical photodynamic therapy for clinical dermatologists.
    The Journal of dermatological treatment, 2019, Volume: 30, Issue:8

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Dermatologists; Humans; Light;

2019
Clinical Guide and Update on Porphyrias.
    Gastroenterology, 2019, Volume: 157, Issue:2

    Topics: Aminolevulinic Acid; Gastroenterology; Gastrointestinal Diseases; Humans; Nervous System Diseases; P

2019
[PDT panoramic view. Principle, photosensitizers, light sources and validated indications in dermatology].
    Annales de dermatologie et de venereologie, 2013, Volume: 140 Suppl 2

    Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Clinical Trials as Topic; Humans; Kerat

2013
[Diagnosis of the porphyrias : From A (as in aminolevulinic acid) to Z (as in zinc protoporphyrin)].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2016, Volume: 67, Issue:3

    Topics: Aminolevulinic Acid; Biomarkers; Diagnosis, Differential; Porphyrias; Protoporphyrins; Reproducibili

2016
Translational medicine in the field of ablative fractional laser (AFXL)-assisted drug delivery: A critical review from basics to current clinical status.
    Journal of the American Academy of Dermatology, 2016, Volume: 74, Issue:5

    Topics: Administration, Cutaneous; Aminolevulinic Acid; Anesthetics; Animals; Cicatrix; Controlled Clinical

2016
The Two Faces of Fractionated Photodynamic Therapy: Increasing Efficacy With Light Fractionation or Adjuvant Use of Fractional Laser Technology.
    Journal of drugs in dermatology : JDD, 2016, Nov-01, Volume: 15, Issue:11

    Topics: Administration, Cutaneous; Aminolevulinic Acid; Clinical Trials as Topic; Combined Modality Therapy;

2016
A critical reappraisal of off-label indications for topical photodynamic therapy with aminolevulinic acid and methylaminolevulinate.
    Reviews on recent clinical trials, 2010, Volume: 5, Issue:2

    Topics: Aminolevulinic Acid; Humans; Photochemotherapy; Rejuvenation; Skin Diseases; Skin Neoplasms

2010
Liposomes in topical photodynamic therapy.
    Expert opinion on drug delivery, 2012, Volume: 9, Issue:8

    Topics: Aminolevulinic Acid; Drug Carriers; Humans; Light; Liposomes; Mesoporphyrins; Photochemotherapy; Pho

2012
Photodynamic therapy and topical aminolevulinic acid: an overview.
    American journal of clinical dermatology, 2003, Volume: 4, Issue:10

    Topics: Administration, Topical; Aminolevulinic Acid; Humans; Photochemotherapy; Photosensitizing Agents; Sk

2003
Topical photodynamic therapy in clinical dermatology.
    The British journal of dermatology, 2004, Volume: 150, Issue:6

    Topics: Adult; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Keratosis; Phot

2004
5-aminolevulinic acid photodynamic therapy: where we have been and where we are going.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2004, Volume: 30, Issue:8

    Topics: Acne Vulgaris; Administration, Cutaneous; Aminolevulinic Acid; Clinical Trials as Topic; Humans; Ker

2004
[The wider application of photodynamic therapy in dermatology].
    Nederlands tijdschrift voor geneeskunde, 2005, Jan-29, Volume: 149, Issue:5

    Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Dermatology; Humans; Keratosis; Photoch

2005
Photodynamic therapy.
    The Australasian journal of dermatology, 2005, Volume: 46 Suppl 3

    Topics: Administration, Topical; Aminolevulinic Acid; Antimetabolites, Antineoplastic; Cryotherapy; Fluorour

2005
Pain, pain relief and other practical issues in photodynamic therapy.
    The Australasian journal of dermatology, 2005, Volume: 46 Suppl 3

    Topics: Administration, Topical; Aminolevulinic Acid; Analgesia; Humans; Pain; Patient Education as Topic; P

2005
Photodynamic therapy of dermatoses other than non-melanoma skin cancer.
    The Australasian journal of dermatology, 2005, Volume: 46 Suppl 3

    Topics: Administration, Topical; Aminolevulinic Acid; Humans; Keratosis; Photochemotherapy; Photosensitizing

2005
[Fluorescence diagnosis in dermatology].
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2003, Volume: 1, Issue:7

    Topics: Aminolevulinic Acid; Image Processing, Computer-Assisted; Optical Imaging; Protoporphyrins; Skin Dis

2003
[Photodynamic therapy in dermatology].
    Actas dermo-sifiliograficas, 2006, Volume: 97, Issue:2

    Topics: Aminolevulinic Acid; Esthetics; Forecasting; Humans; Infrared Rays; Low-Level Light Therapy; Photoch

2006
Photodynamic therapies: principles and present medical applications.
    Bio-medical materials and engineering, 2006, Volume: 16, Issue:4 Suppl

    Topics: Aminolevulinic Acid; Bowen's Disease; Clinical Trials as Topic; Humans; Light; Lipoproteins, LDL; Ma

2006
Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005.
    Journal of the American Academy of Dermatology, 2007, Volume: 56, Issue:1

    Topics: Aminolevulinic Acid; Australia; Basal Cell Nevus Syndrome; Bowen's Disease; Carcinoma, Basal Cell; C

2007
Photodynamic therapy: update 2006. Part 2: Clinical results.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:4

    Topics: Aminolevulinic Acid; Drug Approval; Humans; Photochemotherapy; Photosensitizing Agents; Randomized C

2007
Heme metabolism in erythroid and hepatic cells.
    Progress in hematology, 1983, Volume: 13

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Coproporphyrinogen Oxidase; Erythrocytes; Erythro

1983
Laboratory evaluation in porphyria.
    Seminars in liver disease, 1982, Volume: 2, Issue:2

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Carrier State; Chemistry, Clinical; Diagnosis, Differen

1982
The hepatic porphyrias.
    Progress in medical genetics, 1980, Volume: 4

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Chemical Phenom

1980
The porphyrias--a review.
    Haematologia, 1981, Volume: 14, Issue:3

    Topics: Acute Disease; Aged; Alcoholism; Aminolevulinic Acid; Feces; Female; Heme; Humans; Iron; Liver Disea

1981
5-Aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges.
    Cancer, 1997, Jun-15, Volume: 79, Issue:12

    Topics: Aminolevulinic Acid; Forecasting; Heme; Humans; Neoplasms; Photochemotherapy; Protoporphyrins; Resea

1997
Photodynamic therapy in dermatology.
    Archives of dermatology, 1998, Volume: 134, Issue:2

    Topics: Administration, Cutaneous; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cel

1998
[Use of 5-aminolevulinic acid in photochemotherapy and fluorescence diagnostics].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1998, Mar-20, Volume: 118, Issue:8

    Topics: Aminolevulinic Acid; Fluorescence; Heme; Humans; Photochemotherapy; Protoporphyrins; Skin Diseases;

1998
Topical 5-aminolaevulinic acid photodynamic therapy for the treatment of skin conditions other than non-melanoma skin cancer.
    The British journal of dermatology, 2002, Volume: 146, Issue:2

    Topics: Acne Vulgaris; Aminolevulinic Acid; Humans; Lymphoma, T-Cell; Photochemotherapy; Photosensitizing Ag

2002
Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group.
    The British journal of dermatology, 2002, Volume: 146, Issue:4

    Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Health Care Costs; Humans; Keratosis; L

2002
The advantages of aminolevulinic acid photodynamic therapy in dermatology.
    The Journal of dermatological treatment, 2002, Volume: 13 Suppl 1

    Topics: Aminolevulinic Acid; Humans; Photochemotherapy; Photosensitizing Agents; Skin Diseases

2002
Non-oncologic indications for ALA-PDT.
    The Journal of dermatological treatment, 2002, Volume: 13 Suppl 1

    Topics: Aminolevulinic Acid; Humans; Lichen Sclerosus et Atrophicus; Papillomavirus Infections; Photochemoth

2002
The emerging role of 5-ALA-PDT in dermatology: is PDT superior to standard treatments?
    The Journal of dermatological treatment, 2002, Volume: 13 Suppl 1

    Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Humans; Keratosis; Photochemotherapy; P

2002

Trials

5 trials available for aminolevulinic acid and Skin Diseases

ArticleYear
Prolonged adverse events following photodynamic therapy: regulatory implications.
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Australia; Biopsy; Early Termination of Clinical Trial

2014
A retrospective analysis of real-life practice of off-label photodynamic therapy using methyl aminolevulinate (MAL-PDT) in 20 Italian dermatology departments. Part 1: inflammatory and aesthetic indications.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2013, Volume: 12, Issue:1

    Topics: Acne Vulgaris; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Italy; Light; Ma

2013
A retrospective analysis of real-life practice of off-label photodynamic therapy using methyl aminolevulinate (MAL-PDT) in 20 Italian dermatology departments. Part 2: oncologic and infectious indications.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2013, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Italy; Light; Male;

2013
Topical photodynamic therapy for dermatologic disorders: results and complications.
    Journal of drugs in dermatology : JDD, 2007, Volume: 6, Issue:12

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Dermatitis, Phototox

2007
Long-pulsed dye laser versus long-pulsed dye laser-assisted photodynamic therapy for acne vulgaris: A randomized controlled trial.
    Journal of the American Academy of Dermatology, 2008, Volume: 58, Issue:3

    Topics: Acne Vulgaris; Adult; Aminolevulinic Acid; Edema; Erythema; Female; Fluorescence; Humans; Laser Ther

2008

Other Studies

45 other studies available for aminolevulinic acid and Skin Diseases

ArticleYear
Photobiomodulation and photodynamic therapy applied after electrocauterization for skin healing optimization in rats.
    Journal of biophotonics, 2022, Volume: 15, Issue:5

    Topics: Aminolevulinic Acid; Animals; Electrocoagulation; Female; Photochemotherapy; Rats; Rats, Wistar; Ski

2022
5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) for acneform rash induced by erlotinib: A case report.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 39

    Topics: Acne Vulgaris; Aminolevulinic Acid; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydroc

2022
5-Aminolevulinic acid bypasses mitochondrial complex I deficiency and corrects physiological dysfunctions in Drosophila.
    Human molecular genetics, 2023, 08-07, Volume: 32, Issue:16

    Topics: Adenosine Triphosphate; Aminolevulinic Acid; Animals; Drosophila; Heme Oxygenase-1; Lactates; Mitoch

2023
MAL-associated methyl nicotinate for topical PDT improvement.
    Journal of photochemistry and photobiology. B, Biology, 2020, Volume: 213

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Cell Line; Cell Survival; Humans; Male; NAD;

2020
Drugs to treat dermatologic disorders.
    Nursing, 2017, Volume: 47, Issue:5

    Topics: Aminolevulinic Acid; Antibodies, Monoclonal, Humanized; Calcitriol; Dermatologic Agents; Humans; Ski

2017
Idiopathic elastosis perforans serpiginosa with satisfactory response after 5-ALA photodynamic therapy.
    Photodiagnosis and photodynamic therapy, 2018, Volume: 21

    Topics: Adult; Aminolevulinic Acid; Female; Humans; Photochemotherapy; Photosensitizing Agents; Skin Disease

2018
Let there be light: update on coding for photodynamic therapy and lasers.
    Cutis, 2018, Volume: 101, Issue:3

    Topics: Aminolevulinic Acid; Humans; Laser Therapy; Photochemotherapy; Photosensitizing Agents; Skin Disease

2018
Photodynamic therapy: A real-world analysis of outcomes of photodynamic therapy in an Australian tertiary dermatology clinic.
    The Australasian journal of dermatology, 2019, Volume: 60, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Aminolevulinic Acid; Australia; Cohort Studies; Dermatology; Female; H

2019
Effective treatment of d-penicillamine induced elastosis perforans serpiginosa with ALA-PDT.
    Photodiagnosis and photodynamic therapy, 2015, Volume: 12, Issue:1

    Topics: Adult; Aminolevulinic Acid; Chelating Agents; Humans; Male; Penicillamine; Photochemotherapy; Photos

2015
Photodynamic therapy as an alternative treatment for cutaneous sarcoidosis.
    Dermatology (Basel, Switzerland), 2008, Volume: 217, Issue:4

    Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Ear, External; Eye; Female; Humans; Male; Phot

2008
Desferrioxamine shows different potentials for enhancing 5-aminolaevulinic acid-based photodynamic therapy in several cutaneous cell lines.
    Lasers in medical science, 2010, Volume: 25, Issue:2

    Topics: Aminolevulinic Acid; Cell Death; Cell Line; Deferoxamine; Drug Synergism; Fibroblasts; Humans; Iron

2010
Drug-induced photosensitivity.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Aminolevulinic Acid; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Ca

2009
ALA-PDT for the treatment of cutaneous pseudolymphoma: a case report.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:6

    Topics: Aminolevulinic Acid; Humans; Male; Middle Aged; Photochemotherapy; Photosensitizing Agents; Pseudoly

2010
The relationship between protoporphyrin IX photobleaching during real-time dermatological methyl-aminolevulinate photodynamic therapy (MAL-PDT) and subsequent clinical outcome.
    Lasers in surgery and medicine, 2010, Volume: 42, Issue:7

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Female; Humans

2010
Pseudoepitheliomatous hyperplasia treated by photodynamic therapy with variable irradiation dose and concentration of photosensitizer.
    Photomedicine and laser surgery, 2011, Volume: 29, Issue:2

    Topics: Adult; Aminolevulinic Acid; Epidermis; Female; Humans; Hyperplasia; Middle Aged; Photochemotherapy;

2011
Photodynamic therapy for the treatment of cutaneous sarcoidosis.
    Journal of the American Academy of Dermatology, 2011, Volume: 65, Issue:1

    Topics: Aminolevulinic Acid; Black or African American; Esthetics; Facial Dermatoses; Female; Follow-Up Stud

2011
Retained topical delivery of 5-aminolevulinic acid using cationic ultradeformable liposomes for photodynamic therapy.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Sep-18, Volume: 44, Issue:1-2

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Cations; Drug Compounding; Drug Stability; In

2011
Oxygen saturation and perfusion changes during dermatological methylaminolaevulinate photodynamic therapy.
    The British journal of dermatology, 2011, Volume: 165, Issue:6

    Topics: Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Microcirculation; Oxygen; Photochemoth

2011
Photodynamic therapy using intense pulsed light for cutaneous sarcoidosis.
    The Journal of dermatology, 2012, Volume: 39, Issue:6

    Topics: Administration, Topical; Aminolevulinic Acid; Female; Humans; Middle Aged; Photochemotherapy; Sarcoi

2012
Severe cutaneous reaction to photodynamic therapy with blue light.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:9

    Topics: Aminolevulinic Acid; Follow-Up Studies; Humans; Keratosis, Actinic; Male; Middle Aged; Photochemothe

2011
Oxygen saturation and perfusion changes during photodynamic therapy: use of noninvasive monitoring.
    The British journal of dermatology, 2011, Volume: 165, Issue:6

    Topics: Aminolevulinic Acid; Female; Humans; Male; Oxygen; Photochemotherapy; Photosensitizing Agents; Skin

2011
Colloid milium successfully treated with MAL-PDT.
    International journal of dermatology, 2013, Volume: 52, Issue:6

    Topics: Aminolevulinic Acid; Colloids; Facial Dermatoses; Humans; Male; Middle Aged; Photochemotherapy; Phot

2013
Apoptotic cell death induced by 5-aminolaevulinic acid-mediated photodynamic therapy of hypertrophic scar-derived fibroblasts.
    The Journal of dermatological treatment, 2014, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aminolevulinic Acid; Apoptosis; Cells, Cultured; Child; Cicatrix, Hypertrophic; F

2014
Modelling fluorescence in clinical photodynamic therapy.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2013, Volume: 12, Issue:1

    Topics: Aminolevulinic Acid; Humans; Models, Theoretical; Monte Carlo Method; Photobleaching; Photochemother

2013
Cyclooxygenase-2 is a possible target of treatment approach in conjunction with photodynamic therapy for various disorders in skin and oral cavity.
    The British journal of dermatology, 2004, Volume: 151, Issue:2

    Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Squamous Cell; Cell Division; Cell Line, Tumor; Cyc

2004
Practical aspects of methyl aminolaevulinate photodynamic therapy.
    The Australasian journal of dermatology, 2005, Volume: 46 Suppl 3

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Dose-Response Relationship, Drug; Drug Admini

2005
Methyl aminolaevulinate photodynamic therapy in practice: treatment protocol.
    The Australasian journal of dermatology, 2005, Volume: 46 Suppl 3

    Topics: Administration, Topical; Aminolevulinic Acid; Clinical Protocols; Dose-Response Relationship, Drug;

2005
Successful treatment of lymphadenosis benigna cutis with topical photodynamic therapy with delta-aminolevulinic acid.
    Dermatology (Basel, Switzerland), 2005, Volume: 211, Issue:3

    Topics: Adolescent; Aminolevulinic Acid; Female; Humans; Photochemotherapy; Photosensitizing Agents; Pseudol

2005
Topical 5-aminolevulinic acid-based photodynamic therapy for the treatment of a patient with cutaneous pseudolymphoma.
    Journal of the American Academy of Dermatology, 2005, Volume: 53, Issue:5

    Topics: Administration, Topical; Aminolevulinic Acid; Female; Humans; Middle Aged; Photochemotherapy; Photos

2005
[Dynamic phototherapy in dermatology: current uses and future perspectives].
    Annales de dermatologie et de venereologie, 2006, Volume: 133, Issue:5 Pt 1

    Topics: Aminolevulinic Acid; Humans; Photosensitizing Agents; Phototherapy; Porphyrins; Skin Diseases

2006
The bacterial flora of the skin surface following routine MAL-PDT.
    The Journal of dermatological treatment, 2006, Volume: 17, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Colony Count, Microbial; Female; Humans; Male;

2006
A novel skin cream containing a mixture of human growth factors and cytokines for the treatment of adverse events associated with photodynamic therapy.
    Journal of drugs in dermatology : JDD, 2006, Volume: 5, Issue:8

    Topics: Administration, Topical; Adult; Aminolevulinic Acid; Cytokines; Female; Growth Substances; Humans; O

2006
Epidermoid cysts mimicking recurrence of superficial basal cell carcinoma following photodynamic therapy.
    Clinical and experimental dermatology, 2007, Volume: 32, Issue:2

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Diagnosis, Differential; Epidermal Cyst; Female; Humans;

2007
Pain and photodynamic therapy.
    Dermatology (Basel, Switzerland), 2007, Volume: 215, Issue:3

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Middle Aged; Pain; Pain Measurem

2007
An acute attack of variegate porphyria complicated by severe autonomic neuropathy.
    Australian and New Zealand journal of medicine, 1981, Volume: 11, Issue:1

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Autonomic Nervous System Diseases; Female; Humans; Porpho

1981
Acquired and inherited porphyria: clinical and biochemical features.
    International journal of dermatology, 1982, Volume: 21, Issue:3

    Topics: Aminolevulinic Acid; Chromatography, Thin Layer; Erythrocytes; Female; Humans; Male; Pedigree; Porph

1982
Effects of alcohol on inborn errors of metabolism: porphyria cutanea tarda and hemochromatosis.
    Seminars in hematology, 1980, Volume: 17, Issue:2

    Topics: Alcoholism; Aminolevulinic Acid; Coproporphyrins; Ethanol; Hemochromatosis; Hemosiderosis; Humans; I

1980
Photodynamic therapy for nevus sebaceus with topical delta-aminolevulinic acid.
    Archives of dermatology, 1999, Volume: 135, Issue:6

    Topics: Administration, Topical; Adult; Aminolevulinic Acid; Female; Hamartoma; Humans; Photochemotherapy; P

1999
[Photodiagnostic tests. 3: Fluorescence diagnosis with delta-aminolevulinic acid-induced porphyrins (FDAP) in dermatology].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2000, Volume: 51, Issue:7

    Topics: Aminolevulinic Acid; Fluorescence; Humans; Porphyrins; Sensitivity and Specificity; Skin; Skin Disea

2000
An affordable, portable fluorescence imaging device for skin lesion detection using a dual wavelength approach for image contrast enhancement and aminolaevulinic acid-induced protoporphyrin IX. Part I. Design, spectral and spatial characteristics.
    Lasers in medical science, 2001, Volume: 16, Issue:3

    Topics: Aminolevulinic Acid; Equipment Design; Humans; Image Processing, Computer-Assisted; Photosensitizing

2001
Successful treatment of cutaneous sarcoidosis using topical photodynamic therapy.
    Archives of dermatology, 2002, Volume: 138, Issue:5

    Topics: Aged; Aminolevulinic Acid; Female; Humans; Photochemotherapy; Photosensitizing Agents; Recurrence; S

2002
[Evaluation of the effects of reduced glutathione in subjects with acquired and congenital changes in heme biosynthesis].
    Minerva medica, 1992, Volume: 83, Issue:5

    Topics: Aminolevulinic Acid; Coproporphyrins; Glutathione; Heme; Humans; Lead Poisoning; Porphyrias; Porphyr

1992
The porphyrias.
    American family physician, 1986, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Aminolevulinic Acid; beta Carotene; Bloodletting; Carotenoids; Child; Child, Pres

1986
Washington University case conference. Dual porphyria--an underdiagnosed entity?
    Clinical chemistry, 1987, Volume: 33, Issue:7

    Topics: Aminolevulinic Acid; Coproporphyrins; Diagnosis, Differential; Feces; Flavoproteins; Humans; Male; M

1987
Protoporphyrin accumulation by mitogen stimulated lymphocytes and protoporphyrinogen oxidase activity in patients with porphyria variegata and erythropoietic protoporphyria: evidence for deficiency of protoporphyrinogen oxidase and ferrochelatase in both
    British journal of haematology, 1985, Volume: 60, Issue:1

    Topics: Adult; Aminolevulinic Acid; Child; Edetic Acid; Ferrochelatase; Flavoproteins; Humans; Iron; Liver D

1985