Page last updated: 2024-10-16

aminolevulinic acid and Sarcopenia

aminolevulinic acid has been researched along with Sarcopenia in 2 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Sarcopenia: Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles.

Research Excerpts

ExcerptRelevanceReference
" Although this study suggests safe administration and the possibility of ALA improving hand grip strength in patients with sarcopenia, further investigation is required."7.30Efficacy and Safety of 5-Aminolevulinic Acid Combined with Iron on Skeletal Muscle Mass Index and Physical Performance of Patients with Sarcopenia: A Multicenter, Double-Blinded, Randomized-Controlled Trial (ALADDIN Study). ( Abe, Y; Hiyoshi, T; Inoue, I; Kaga, H; Kuribayashi, N; Seino, H; Tamura, Y; Watada, H; Yoshii, H, 2023)
" This study aimed to assess the efficacy and dose dependency of ALA combined with iron in sarcopenia by measuring skeletal muscle mass index (SMI)."7.30Efficacy and Safety of 5-Aminolevulinic Acid Combined with Iron on Skeletal Muscle Mass Index and Physical Performance of Patients with Sarcopenia: A Multicenter, Double-Blinded, Randomized-Controlled Trial (ALADDIN Study). ( Abe, Y; Hiyoshi, T; Inoue, I; Kaga, H; Kuribayashi, N; Seino, H; Tamura, Y; Watada, H; Yoshii, H, 2023)
"Sarcopenia is a geriatric syndrome characterized by decreased physical performance, muscle mass, and strength."7.30Efficacy and Safety of 5-Aminolevulinic Acid Combined with Iron on Skeletal Muscle Mass Index and Physical Performance of Patients with Sarcopenia: A Multicenter, Double-Blinded, Randomized-Controlled Trial (ALADDIN Study). ( Abe, Y; Hiyoshi, T; Inoue, I; Kaga, H; Kuribayashi, N; Seino, H; Tamura, Y; Watada, H; Yoshii, H, 2023)
"Recently, sarcopenia has attracted attention as therapeutic target because it constitutes a risk factor for metabolic and cardiovascular diseases."5.46Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid. ( Endo, S; Fujii, C; Fujii, K; Hagiwara, A; Inoue, H; Itoh, H; Kawai, T; Mitsuishi, M; Miyashita, K; Muraki, A; Nakajima, M; Ryuzaki, M; Sato, M; Tamaki, M; Tanaka, T; Uto, A, 2017)
" Although this study suggests safe administration and the possibility of ALA improving hand grip strength in patients with sarcopenia, further investigation is required."3.30Efficacy and Safety of 5-Aminolevulinic Acid Combined with Iron on Skeletal Muscle Mass Index and Physical Performance of Patients with Sarcopenia: A Multicenter, Double-Blinded, Randomized-Controlled Trial (ALADDIN Study). ( Abe, Y; Hiyoshi, T; Inoue, I; Kaga, H; Kuribayashi, N; Seino, H; Tamura, Y; Watada, H; Yoshii, H, 2023)
" This study aimed to assess the efficacy and dose dependency of ALA combined with iron in sarcopenia by measuring skeletal muscle mass index (SMI)."3.30Efficacy and Safety of 5-Aminolevulinic Acid Combined with Iron on Skeletal Muscle Mass Index and Physical Performance of Patients with Sarcopenia: A Multicenter, Double-Blinded, Randomized-Controlled Trial (ALADDIN Study). ( Abe, Y; Hiyoshi, T; Inoue, I; Kaga, H; Kuribayashi, N; Seino, H; Tamura, Y; Watada, H; Yoshii, H, 2023)
"Sarcopenia is a geriatric syndrome characterized by decreased physical performance, muscle mass, and strength."3.30Efficacy and Safety of 5-Aminolevulinic Acid Combined with Iron on Skeletal Muscle Mass Index and Physical Performance of Patients with Sarcopenia: A Multicenter, Double-Blinded, Randomized-Controlled Trial (ALADDIN Study). ( Abe, Y; Hiyoshi, T; Inoue, I; Kaga, H; Kuribayashi, N; Seino, H; Tamura, Y; Watada, H; Yoshii, H, 2023)
"Recently, sarcopenia has attracted attention as therapeutic target because it constitutes a risk factor for metabolic and cardiovascular diseases."1.46Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid. ( Endo, S; Fujii, C; Fujii, K; Hagiwara, A; Inoue, H; Itoh, H; Kawai, T; Mitsuishi, M; Miyashita, K; Muraki, A; Nakajima, M; Ryuzaki, M; Sato, M; Tamaki, M; Tanaka, T; Uto, A, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Tamura, Y1
Kaga, H1
Abe, Y1
Yoshii, H1
Seino, H1
Hiyoshi, T1
Kuribayashi, N1
Inoue, I1
Watada, H1
Fujii, C1
Miyashita, K1
Mitsuishi, M1
Sato, M1
Fujii, K1
Inoue, H1
Hagiwara, A1
Endo, S1
Uto, A1
Ryuzaki, M1
Nakajima, M1
Tanaka, T1
Tamaki, M1
Muraki, A1
Kawai, T1
Itoh, H1

Trials

1 trial available for aminolevulinic acid and Sarcopenia

ArticleYear
Efficacy and Safety of 5-Aminolevulinic Acid Combined with Iron on Skeletal Muscle Mass Index and Physical Performance of Patients with Sarcopenia: A Multicenter, Double-Blinded, Randomized-Controlled Trial (ALADDIN Study).
    Nutrients, 2023, Jun-24, Volume: 15, Issue:13

    Topics: Aged; Aminolevulinic Acid; Animals; Hand Strength; Humans; Iron; Mice; Muscle Strength; Muscle, Skel

2023

Other Studies

1 other study available for aminolevulinic acid and Sarcopenia

ArticleYear
Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid.
    Scientific reports, 2017, 06-21, Volume: 7, Issue:1

    Topics: Aminolevulinic Acid; Animals; Blood Glucose; Body Weight; Disease Models, Animal; Electron Transport

2017