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aminolevulinic acid and Sarcoma

aminolevulinic acid has been researched along with Sarcoma in 6 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.

Research Excerpts

ExcerptRelevanceReference
"In this context, we, for the first time, assessed 5-aminolevulinic acid (5-ALA)-PDT-mediated anti-cancer activity and its molecular mechanism after continuous wave (CW) and pulse radiation (PR) on three different histological types (liposarcoma, chondrosarcoma, and osteosarcoma) of CMST cells by WST-1, Annexin V, ROS, acridine orange/propidium iodide staining, RT-PCR, and western blot analysis."8.31Comparison of the anti-cancer activity of 5-aminolevulinic acid-mediated photodynamic therapy after continuous wave and pulse irradiation in different histological types of canine mammary sarcoma tumors. ( Armutak, EI; Baykal, A; Deveci Ozkan, A; Guney Eskiler, G; Kaleli, S; Kamanli, AF; Kasikci, G; Lim, HS; Ozten, O; Turna, O; Yildirim, F; Yildiz, SZ, 2023)
"In this article, we present the case of a seven-year-old boy who received surgical treatment for a left frontal tumor after oral administration of 5-aminolevulinic acid (5-ALA); the definitive histological diagnosis of which was meningeal sarcoma."7.81Fluorescence-guided resection with 5-aminolevulinic acid of meningeal sarcoma in a child. ( Bernal García, LM; Cabezudo Artero, JM; López Macías, M; Marcelo Zamorano, MB; Royano Sánchez, M, 2015)
"The role of multi-drug resistance (MDR1) and its product, P-glycoprotein (P-gp) on 5-aminolevulinic acid hexyl ester (Hexyl-ALA) mediated phototoxicity was determined with human uterine sarcoma cells, MES-SA control and MDR1 expressing MES-SA-Dx5."7.74Effects of photoactivated 5-aminolevulinic acid hexyl ester on MDR1 over-expressing human uterine sarcoma cells. ( Chu, ES; Ho, RJ; Shi, M; Yow, CM, 2008)
"Meningeal sarcomas are rare, highly aggressive malignant tumors, predominately affecting the pediatric population and have a poor prognosis in spite of treatment."5.42Fluorescence-guided resection with 5-aminolevulinic acid of meningeal sarcoma in a child. ( Bernal García, LM; Cabezudo Artero, JM; López Macías, M; Marcelo Zamorano, MB; Royano Sánchez, M, 2015)
"In this context, we, for the first time, assessed 5-aminolevulinic acid (5-ALA)-PDT-mediated anti-cancer activity and its molecular mechanism after continuous wave (CW) and pulse radiation (PR) on three different histological types (liposarcoma, chondrosarcoma, and osteosarcoma) of CMST cells by WST-1, Annexin V, ROS, acridine orange/propidium iodide staining, RT-PCR, and western blot analysis."4.31Comparison of the anti-cancer activity of 5-aminolevulinic acid-mediated photodynamic therapy after continuous wave and pulse irradiation in different histological types of canine mammary sarcoma tumors. ( Armutak, EI; Baykal, A; Deveci Ozkan, A; Guney Eskiler, G; Kaleli, S; Kamanli, AF; Kasikci, G; Lim, HS; Ozten, O; Turna, O; Yildirim, F; Yildiz, SZ, 2023)
"In this article, we present the case of a seven-year-old boy who received surgical treatment for a left frontal tumor after oral administration of 5-aminolevulinic acid (5-ALA); the definitive histological diagnosis of which was meningeal sarcoma."3.81Fluorescence-guided resection with 5-aminolevulinic acid of meningeal sarcoma in a child. ( Bernal García, LM; Cabezudo Artero, JM; López Macías, M; Marcelo Zamorano, MB; Royano Sánchez, M, 2015)
"The role of multi-drug resistance (MDR1) and its product, P-glycoprotein (P-gp) on 5-aminolevulinic acid hexyl ester (Hexyl-ALA) mediated phototoxicity was determined with human uterine sarcoma cells, MES-SA control and MDR1 expressing MES-SA-Dx5."3.74Effects of photoactivated 5-aminolevulinic acid hexyl ester on MDR1 over-expressing human uterine sarcoma cells. ( Chu, ES; Ho, RJ; Shi, M; Yow, CM, 2008)
"Meningeal sarcomas are rare, highly aggressive malignant tumors, predominately affecting the pediatric population and have a poor prognosis in spite of treatment."1.42Fluorescence-guided resection with 5-aminolevulinic acid of meningeal sarcoma in a child. ( Bernal García, LM; Cabezudo Artero, JM; López Macías, M; Marcelo Zamorano, MB; Royano Sánchez, M, 2015)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Turna, O1
Deveci Ozkan, A1
Guney Eskiler, G1
Baykal, A1
Ozten, O1
Yildirim, F1
Armutak, EI1
Kamanli, AF1
Lim, HS1
Kaleli, S1
Kasikci, G1
Yildiz, SZ1
Horii, S1
Mori, S1
Ogata, R1
Nukaga, S1
Nishida, R1
Kishi, S1
Sasaki, R1
Ikemoto, A1
Owari, T1
Maesaka, F1
Honoki, K1
Miyake, M1
Tanaka, Y1
Fujimoto, K1
Fujiwara-Tani, R1
Kuniyasu, H1
Bernal García, LM1
Cabezudo Artero, JM1
Royano Sánchez, M1
Marcelo Zamorano, MB1
López Macías, M1
Chu, ES1
Yow, CM1
Shi, M1
Ho, RJ1
Kelleher, DK2
Bastian, J1
Thews, O2
Vaupel, P2
Frank, J1
Lambert, C1
Biesalski, HK1

Other Studies

6 other studies available for aminolevulinic acid and Sarcoma

ArticleYear
Comparison of the anti-cancer activity of 5-aminolevulinic acid-mediated photodynamic therapy after continuous wave and pulse irradiation in different histological types of canine mammary sarcoma tumors.
    Lasers in medical science, 2023, Feb-13, Volume: 38, Issue:1

    Topics: Aminolevulinic Acid; Animals; Apoptosis; Cell Line, Tumor; Chondrosarcoma; Dogs; Liposarcoma; Photoc

2023
5-Aminolevrinic Acid Exhibits Dual Effects on Stemness in Human Sarcoma Cell Lines under Dark Conditions.
    International journal of molecular sciences, 2023, Mar-24, Volume: 24, Issue:7

    Topics: Aminolevulinic Acid; Apoptosis; Cell Death; Cell Line; Heme Oxygenase-1; Humans; Protoporphyrins; Sa

2023
Fluorescence-guided resection with 5-aminolevulinic acid of meningeal sarcoma in a child.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015, Volume: 31, Issue:7

    Topics: Aminolevulinic Acid; Child; Diagnostic Imaging; Humans; Male; Meningeal Neoplasms; Neurosurgical Pro

2015
Effects of photoactivated 5-aminolevulinic acid hexyl ester on MDR1 over-expressing human uterine sarcoma cells.
    Toxicology letters, 2008, Volume: 181, Issue:1

    Topics: Aminolevulinic Acid; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter

2008
Enhanced effects of aminolaevulinic acid-based photodynamic therapy through local hyperthermia in rat tumours.
    British journal of cancer, 2003, Jul-21, Volume: 89, Issue:2

    Topics: Aminolevulinic Acid; Animals; Cell Death; Disease Models, Animal; Hyperthermia, Induced; Male; Photo

2003
Intensified oxidative and nitrosative stress following combined ALA-based photodynamic therapy and local hyperthermia in rat tumors.
    International journal of cancer, 2003, Dec-20, Volume: 107, Issue:6

    Topics: Aminolevulinic Acid; Animals; Apoptosis; Cell Division; Gene Expression Regulation, Neoplastic; Glut

2003