Page last updated: 2024-10-16

aminolevulinic acid and Renal Insufficiency

aminolevulinic acid has been researched along with Renal Insufficiency in 5 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
"The quantification of delta-aminolevulinic acid (ALA) and porphobilinogen (PBG) in urine are the first-line tests for diagnosis and monitoring of acute hepatic porphyrias (AHP)."4.31Quantification of Urine and Plasma Porphyrin Precursors Using LC-MS in Acute Hepatic Porphyrias: Improvement in Routine Diagnosis and in the Monitoring of Kidney Failure Patients. ( Dessendier, N; Gouya, L; Junot, C; Lefebvre, T; Manceau, H; Moulouel, B; Nguyen, AL; Poli, A; Puy, H; Schmitt, C; Talbi, N, 2023)
" We have investigated the effect of repetitive acute attacks on renal function and the effect of total or five-sixth nephrectomy causing renal insufficiency on hepatic heme synthesis in the porphobilinogen deaminase (PBGD)-deficient (AIP) mouse."3.78Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse. ( Enríquez de Salamanca, R; Fontanellas, A; Harper, P; Mauleón, I; Prieto, J; Salido, E; Sampedro, A; Sardh, E; Unzu, C, 2012)
"Headache is common in PRES, though headache associated with PRES was not identified as a separate entity in the 2018 International Classification of Headache Disorders."2.72Posterior Reversible Encephalopathy Syndrome. ( Gao, V; Gewirtz, AN; Parauda, SC; Robbins, MS, 2021)
"Associations with PRES include renal failure, preeclampsia and eclampsia, autoimmune conditions, and immunosuppression."2.72Posterior Reversible Encephalopathy Syndrome. ( Gao, V; Gewirtz, AN; Parauda, SC; Robbins, MS, 2021)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Poli, A1
Manceau, H1
Nguyen, AL1
Moulouel, B1
Dessendier, N1
Talbi, N1
Puy, H1
Junot, C1
Gouya, L1
Schmitt, C1
Lefebvre, T1
Gewirtz, AN1
Gao, V1
Parauda, SC1
Robbins, MS1
Unzu, C1
Sampedro, A1
Sardh, E1
Mauleón, I1
Enríquez de Salamanca, R1
Prieto, J1
Salido, E1
Harper, P1
Fontanellas, A1
Bruneau, N1
St-Vil, D1
Luks, FI1
LaBerge, JM1
Bensoussan, AL1
Blanchard, H1
Goujon, R1
Philibert, E1
Bernard, P1
Normand, J1
Boucherat, M1

Reviews

1 review available for aminolevulinic acid and Renal Insufficiency

ArticleYear
Posterior Reversible Encephalopathy Syndrome.
    Current pain and headache reports, 2021, Feb-25, Volume: 25, Issue:3

    Topics: Acute Chest Syndrome; Aminolevulinic Acid; Anemia, Sickle Cell; Autoimmune Diseases; Blood-Brain Bar

2021

Other Studies

4 other studies available for aminolevulinic acid and Renal Insufficiency

ArticleYear
Quantification of Urine and Plasma Porphyrin Precursors Using LC-MS in Acute Hepatic Porphyrias: Improvement in Routine Diagnosis and in the Monitoring of Kidney Failure Patients.
    Clinical chemistry, 2023, 10-03, Volume: 69, Issue:10

    Topics: Aminolevulinic Acid; Chromatography, Liquid; Humans; Porphobilinogen; Porphyrias; Porphyrias, Hepati

2023
Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Enzyme Activation; Female; Heme; Hydroxymethyl

2012
[Surgical and metabolic aspects of liver transplantation for tyrosinemia].
    Annales de chirurgie, 1993, Volume: 47, Issue:9

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Central Nervous System Diseas

1993
Determination of plasma delta-aminolaevulinic acid levels. Applications.
    Annales de biologie clinique, 1992, Volume: 50, Issue:10-11

    Topics: Aminolevulinic Acid; Anticonvulsants; Female; Humans; Lead Poisoning; Male; Porphyrias; Renal Dialys

1992